2VPG

decoding of methylated histone h3 tail by the pygo-bcl9 wnt signaling complex

• Total interactions analyzed: 15
• Total true interactions: 7
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 54
  • Norm. En. per Res.: -4.2466
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-62.1252	5.4681	-167.349	-224.0061	55	7	14	6517	0	4	3
A-C	0.0	4.9509	-50.6209	-45.67	28	0	1	2105	0	1	2
A-P	-20.3753	0.0	-90.695	-111.0703	36	1	4	2993	0	0	0
B-P	0.0	0.0	-0.0679	-0.0679	5	0	0	29	0	0	0
C-D	-65.8935	5.3393	-168.762	-229.3162	54	8	14	6423	0	4	3
C-R	-19.8228	0.0	-89.2224	-109.0452	35	6	4	2982	0	0	0
D-R	0.0	0.0	-0.0545	-0.0545	5	0	0	27	0	0	0

Interface residues

• A-B: ALA175B, ALA185B, ALA188B, ALA189B, ALA191B, ALA361A, ALA378A, ALA384A, ALA386A, ALA388A, ALA397A, ARG369A, ASN186B, ASP393A, CYS359A, CYS371A, CYS392A, CYS395A, GLU183B, GLU190B, GLU360A, GLU376A, GLU385A, GLY174B, GLY373A, GLY380A, GLY391A, ILE345A, ILE357A, ILE370A, LEU193B, LEU381A, LEU382A, LYS187B, MET176B, MET184B, MET374A, MET396A, PHE180B, PHE367A, SER181B, SER362A, SER387A, THR182B, THR372A, THR375A, THR377A, TRP390A, TYR178B, TYR379A, VAL177B, VAL179B, VAL192B, VAL197B, VAL389A
• A-C: ARG369A, ARG369C, ASN348A, ASN348C, ASP393A, ASP393C, CYS343A, CYS343C, CYS346A, CYS346C, CYS371A, CYS371C, GLN354A, GLN354C, GLY344A, GLY344C, GLY373A, GLY373C, HIS368A, HIS368C, ILE345A, ILE345C, ILE370A, ILE370C, THR347A, THR347C, THR372A, THR372C
• A-P: ALA1P, ALA356A, ALA361A, ALA378A, ALA384A, ALA386A, ALA388A, ALA7P, ARG369A, ASP352A, ASP353A, ASP355A, CYS359A, GLN354A, GLN5P, GLU360A, GLU376A, GLU385A, GLY380A, GLY391A, ILE357A, LEU358A, LEU381A, LEU382A, MET374A, PHE367A, SER387A, THR377A, THR383A, THR3P, THR6P, TRP366A, TRP390A, TYR379A, VAL350A, VAL389A
• B-P: ALA1P, PHE180B, TYR178B, VAL177B, VAL179B
• C-D: ALA175D, ALA185D, ALA188D, ALA189D, ALA191D, ALA361C, ALA378C, ALA386C, ALA388C, ALA397C, ARG369C, ASN186D, ASP393C, CYS359C, CYS371C, CYS392C, CYS395C, GLU183D, GLU190D, GLU360C, GLU376C, GLU385C, GLY174D, GLY373C, GLY380C, GLY391C, ILE345C, ILE357C, ILE370C, LEU193D, LEU381C, LEU382C, LYS187D, LYS194D, MET176D, MET184D, MET374C, MET396C, PHE180D, SER181D, SER362C, SER387C, THR182D, THR372C, THR375C, THR377C, TRP390C, TYR178D, TYR379C, VAL177D, VAL179D, VAL192D, VAL197D, VAL389C
• C-R: ALA1R, ALA356C, ALA361C, ALA378C, ALA384C, ALA386C, ALA388C, ALA7R, ARG369C, ASP352C, ASP353C, ASP355C, CYS359C, GLN354C, GLN5R, GLU360C, GLU376C, GLU385C, GLY380C, GLY391C, ILE357C, LEU358C, LEU381C, LEU382C, MET374C, PHE367C, SER387C, THR383C, THR3R, THR6R, TRP366C, TRP390C, TYR379C, VAL350C, VAL389C
• D-R: ALA1R, PHE180D, TYR178D, VAL177D, VAL179D