2VPD

decoding of methylated histone h3 tail by the pygo-bcl9 wnt signaling complex

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 37
  • Norm. En. per Res.: -5.8432
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-60.0308	5.9317	-192.476	-246.5751	60	7	15	7756	0	6	3
A-C	-27.39	-2.3214	-108.488	-138.1994	55	3	0	3958	0	7	14
A-D	-8.8803	-4.2611	-12.8083	-25.9497	21	1	0	762	0	3	0
B-C	-3.4839	-4.8725	-7.9898	-16.3462	18	0	0	539	0	2	0
B-D	-78.1148	0.735	-138.82	-216.1998	37	9	11	5260	0	0	1
C-D	-65.963	4.2126	-187.271	-249.0214	60	5	16	7787	0	5	3

Interface residues

• A-B: ALA185B, ALA188B, ALA189B, ALA191B, ALA361A, ALA378A, ALA384A, ALA386A, ALA388A, ALA397A, ARG369A, ASN186B, ASP393A, CYS359A, CYS371A, CYS392A, CYS395A, GLU183B, GLU190B, GLU198B, GLU360A, GLU376A, GLU385A, GLY373A, GLY380A, GLY391A, ILE200B, ILE345A, ILE357A, ILE370A, LEU193B, LEU381A, LEU382A, LYS175B, LYS187B, MET184B, MET374A, MET396A, PHE180B, PHE203B, SER181B, SER202B, SER362A, SER387A, THR182B, THR199B, THR372A, THR375A, THR377A, THR383A, TRP390A, TYR178B, TYR379A, VAL176B, VAL177B, VAL179B, VAL192B, VAL197B, VAL201B, VAL389A
• A-C: ALA356A, ALA361A, ALA361C, ALA384A, ALA384C, ALA386A, ALA386C, ALA388A, ARG369A, ASN351A, ASP338C, ASP352A, ASP352C, ASP353A, ASP355A, CYS359A, CYS359C, CYS363A, CYS363C, GLN354A, GLN364A, GLN364C, GLU360A, GLU360C, GLU376A, GLU385A, GLU385C, GLY333C, GLY380A, HIS334C, HIS368A, ILE357A, LEU358A, LEU358C, LEU381A, LEU382A, MET332C, PHE367A, SER335C, SER336C, SER337C, SER362A, SER362C, SER387A, SER387C, THR383A, THR383C, TRP366A, TRP366C, TRP390A, TYR341A, TYR379A, VAL350A, VAL389A, VAL389C
• A-D: ALA171D, ALA173D, ALA174D, ALA361A, ALA388A, ALA397A, ASP393A, CYS359A, CYS392A, CYS395A, GLN364A, GLU360A, GLY391A, LYS175D, MET172D, MET396A, SER362A, SER387A, TRP390A, VAL177D, VAL389A
• B-C: ALA173B, ALA174B, ALA361C, ALA386C, ALA388C, CYS359C, GLN364C, GLU360C, GLY391C, LYS175B, MET172B, MET332C, MET396C, SER362C, SER387C, TRP390C, VAL177B, VAL389C
• B-D: ALA171D, ALA173B, ALA173D, ALA174B, ALA174D, ALA185B, ALA188B, ALA188D, GLU183B, HIS204D, ILE200B, ILE200D, ILE205D, LYS175B, LYS175D, LYS187B, MET172B, MET172D, MET184B, MET184D, PHE180B, PHE180D, PHE203B, PHE203D, SER181B, SER181D, THR182B, TYR178B, TYR178D, VAL176B, VAL176D, VAL177B, VAL177D, VAL179B, VAL179D, VAL201B, VAL201D
• C-D: ALA185D, ALA188D, ALA189D, ALA191D, ALA361C, ALA378C, ALA384C, ALA386C, ALA388C, ALA397C, ARG369C, ASN186D, ASP393C, CYS359C, CYS371C, CYS392C, CYS395C, GLU183D, GLU190D, GLU198D, GLU360C, GLU376C, GLU385C, GLY373C, GLY380C, GLY391C, ILE200D, ILE345C, ILE357C, LEU193D, LEU358C, LEU381C, LEU382C, LYS175D, LYS187D, MET184D, MET374C, MET396C, PHE180D, PHE203D, SER181D, SER202D, SER362C, SER387C, THR182D, THR199D, THR372C, THR375C, THR377C, THR383C, TRP390C, TYR178D, TYR379C, VAL176D, VAL177D, VAL179D, VAL192D, VAL197D, VAL201D, VAL389C