2VDW

guanosine n7 methyl-transferase sub-complex (d1-d12) of the vaccinia virus mrna capping enzyme

• Total interactions analyzed: 28
• Total true interactions: 7
• Strongest Interaction:
  • Chains: G-H
  • Int. Res.: 151
  • Norm. En. per Res.: -3.2385
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-34.0152	-29.7507	-371.457	-435.2229	150	19	13	16147	5	36	35
A-F	-14.0689	4.7373	-150.732	-160.0637	79	5	2	6438	2	30	28
B-D	-39.301	-25.9639	-127.996	-193.2609	92	23	0	5202	0	66	55
C-D	-34.434	-30.9063	-378.15	-443.4902	151	18	13	16385	5	36	34
C-H	-19.0191	6.7025	-149.46	-161.7765	80	11	2	6633	2	31	29
E-F	-38.4006	-46.8933	-358.992	-444.2859	149	9	13	15972	4	36	36
G-H	-65.2288	-45.7418	-378.041	-489.0115	151	12	13	16690	3	38	36

Interface residues

• A-B: ALA255B, ALA41B, ALA802A, ARG114B, ARG163B, ARG251B, ARG281B, ARG49B, ARG55B, ARG592A, ARG794A, ARG808A, ARG812A, ASN126B, ASN127B, ASN234B, ASN235B, ASN243B, ASN250B, ASN42B, ASN51B, ASN54B, ASN570A, ASN785A, ASN7B, ASN800A, ASN818A, ASP132B, ASP238B, ASP2B, ASP52B, ASP587A, ASP588A, ASP784A, ASP787A, ASP807A, CYS581A, GLN229B, GLN46B, GLU125B, GLU240B, GLU247B, GLU254B, GLU38B, GLU3B, GLU612A, GLU793A, GLU806A, GLY162B, GLY40B, GLY611A, GLY704A, GLY801A, HIS260B, HIS278B, ILE117B, ILE130B, ILE166B, ILE242B, ILE47B, ILE4B, ILE577A, ILE709A, ILE791A, ILE792A, ILE799A, LEU128B, LEU246B, LEU256B, LEU262B, LEU263B, LEU282B, LEU34B, LEU37B, LEU45B, LEU53B, LEU575A, LEU576A, LEU586A, LEU708A, LEU782A, LYS111B, LYS134B, LYS244B, LYS277B, LYS31B, LYS573A, LYS583A, LYS591A, LYS607A, LYS706A, LYS768A, LYS796A, LYS797A, MET1B, MET579A, MET805A, PHE161B, PHE241B, PHE245B, PHE44B, PHE585A, PHE788A, PHE798A, PHE814A, PHE815A, PRO236B, PRO33B, PRO35B, SER119B, SER131B, SER261B, SER265B, SER32B, SER36B, SER48B, SER578A, SER582A, SER589A, SER795A, SER803A, SER842A, THR124B, THR239B, THR268B, THR574A, THR584A, THR710A, THR790A, THR804A, THR811A, TYR133B, TYR253B, TYR257B, TYR258B, TYR264B, TYR39B, TYR43B, TYR571A, TYR580A, TYR610A, TYR839A, VAL237B, VAL259B, VAL50B, VAL572A, VAL783A, VAL786A, VAL838A, VAL840A
• A-F: ALA101F, ALA105F, ARG106F, ARG112F, ARG142F, ARG560A, ARG562A, ARG92F, ASN107F, ASN226F, ASN558A, ASN731A, ASN737A, ASP102F, ASP139F, ASP146F, ASP224F, ASP76F, ASP828A, GLU72F, GLU736A, GLU742A, GLY826A, GLY91F, HIS729A, ILE155F, ILE727A, ILE728A, LEU103F, LEU732A, LEU75F, LEU827A, LYS108F, LYS111F, LYS156F, LYS223F, LYS559A, LYS723A, LYS724A, LYS730A, LYS88F, MET135F, MET739A, PHE138F, PHE726A, PRO143F, PRO158F, PRO71F, PRO733A, PRO754A, PRO760A, SER104F, SER221F, SER227F, SER734A, SER735A, SER73F, SER740A, SER758A, THR137F, THR557A, THR561A, THR725A, THR759A, TRP222F, TYR129F, TYR738A, TYR752A, TYR79F, TYR89F, TYR90F, VAL100F, VAL140F, VAL225F, VAL228F, VAL741A, VAL750A, VAL751A, VAL87F
• B-D: ALA101B, ALA101D, ALA105B, ALA105D, ALA116B, ALA116D, ARG106B, ARG106D, ARG112B, ARG112D, ARG114B, ARG114D, ARG142B, ARG142D, ARG92B, ARG92D, ASN107B, ASN107D, ASN127B, ASN127D, ASN226B, ASN226D, ASP102B, ASP102D, ASP115B, ASP115D, ASP139B, ASP139D, ASP146B, ASP146D, ASP224B, ASP224D, ASP59B, ASP59D, ASP76B, ASP76D, GLU113B, GLU113D, GLU125B, GLU125D, GLY91B, GLY91D, HIS66B, HIS66D, LEU61B, LEU61D, LEU75B, LEU75D, LYS108B, LYS108D, LYS223B, LYS223D, LYS62B, LYS62D, LYS88B, LYS88D, MET56B, MET56D, MET60B, MET60D, MET69B, PHE110B, PHE110D, PRO57B, PRO57D, PRO71B, PRO71D, SER227B, SER227D, SER93B, THR58B, THR58D, THR94B, THR94D, TRP222B, TRP222D, TYR129B, TYR129D, TYR79B, TYR79D, TYR89B, TYR89D, TYR90B, TYR90D, VAL100B, VAL100D, VAL225B, VAL225D, VAL228B, VAL228D, VAL87B, VAL87D
• C-D: ALA255D, ALA41D, ALA802C, ARG114D, ARG163D, ARG251D, ARG281D, ARG49D, ARG55D, ARG592C, ARG794C, ARG808C, ARG812C, ASN126D, ASN127D, ASN234D, ASN235D, ASN243D, ASN250D, ASN42D, ASN51D, ASN54D, ASN570C, ASN785C, ASN7D, ASN800C, ASN818C, ASP132D, ASP238D, ASP2D, ASP52D, ASP587C, ASP588C, ASP784C, ASP787C, ASP807C, CYS581C, GLN229D, GLN46D, GLU125D, GLU240D, GLU247D, GLU254D, GLU38D, GLU3D, GLU612C, GLU793C, GLU806C, GLY162D, GLY40D, GLY611C, GLY704C, GLY801C, HIS260D, HIS278D, ILE117D, ILE130D, ILE166D, ILE242D, ILE47D, ILE4D, ILE577C, ILE709C, ILE791C, ILE792C, ILE799C, LEU128D, LEU246D, LEU256D, LEU262D, LEU263D, LEU282D, LEU285D, LEU34D, LEU37D, LEU45D, LEU53D, LEU575C, LEU576C, LEU586C, LEU708C, LEU782C, LYS111D, LYS134D, LYS244D, LYS277D, LYS31D, LYS573C, LYS583C, LYS591C, LYS607C, LYS706C, LYS768C, LYS796C, LYS797C, MET1D, MET579C, MET805C, PHE161D, PHE241D, PHE245D, PHE44D, PHE585C, PHE788C, PHE798C, PHE814C, PHE815C, PRO236D, PRO33D, PRO35D, SER119D, SER131D, SER261D, SER265D, SER32D, SER36D, SER48D, SER578C, SER582C, SER589C, SER795C, SER803C, SER842C, THR124D, THR239D, THR268D, THR574C, THR584C, THR710C, THR790C, THR804C, THR811C, TYR133D, TYR253D, TYR257D, TYR258D, TYR264D, TYR39D, TYR43D, TYR571C, TYR580C, TYR610C, TYR839C, VAL237D, VAL259D, VAL50D, VAL572C, VAL783C, VAL786C, VAL838C, VAL840C
• C-H: ALA101H, ALA105H, ARG106H, ARG112H, ARG142H, ARG560C, ARG92H, ASN107H, ASN226H, ASN558C, ASN731C, ASN737C, ASP102H, ASP139H, ASP146H, ASP224H, ASP722C, ASP76H, ASP828C, GLU72H, GLU736C, GLU742C, GLY826C, GLY91H, HIS729C, ILE155H, ILE727C, ILE728C, LEU103H, LEU732C, LEU75H, LEU827C, LYS108H, LYS111H, LYS156H, LYS223H, LYS559C, LYS723C, LYS724C, LYS730C, LYS88H, MET135H, MET739C, PHE138H, PHE726C, PRO143H, PRO158H, PRO71H, PRO733C, PRO754C, PRO760C, SER104H, SER219H, SER221H, SER227H, SER734C, SER735C, SER73H, SER740C, SER758C, THR137H, THR557C, THR561C, THR725C, THR759C, TRP222H, TYR129H, TYR738C, TYR752C, TYR79H, TYR89H, TYR90H, VAL100H, VAL140H, VAL225H, VAL228H, VAL741C, VAL750C, VAL751C, VAL87H
• E-F: ALA255F, ALA41F, ALA802E, ARG114F, ARG163F, ARG251F, ARG281F, ARG49F, ARG55F, ARG592E, ARG794E, ARG808E, ARG812E, ASN126F, ASN127F, ASN234F, ASN235F, ASN243F, ASN250F, ASN42F, ASN51F, ASN54F, ASN570E, ASN590E, ASN785E, ASN7F, ASN800E, ASN818E, ASP132F, ASP238F, ASP52F, ASP587E, ASP588E, ASP784E, ASP787E, ASP807E, CYS581E, GLN229F, GLN46F, GLU125F, GLU240F, GLU247F, GLU254F, GLU38F, GLU3F, GLU612E, GLU793E, GLU806E, GLY162F, GLY40F, GLY611E, GLY704E, GLY801E, HIS260F, HIS278F, ILE117F, ILE130F, ILE166F, ILE242F, ILE47F, ILE4F, ILE577E, ILE791E, ILE792E, ILE799E, LEU128F, LEU246F, LEU256F, LEU262F, LEU263F, LEU34F, LEU37F, LEU45F, LEU53F, LEU575E, LEU576E, LEU586E, LEU708E, LEU782E, LYS111F, LYS134F, LYS244F, LYS31F, LYS573E, LYS583E, LYS591E, LYS607E, LYS706E, LYS768E, LYS796E, LYS797E, MET1F, MET579E, MET805E, PHE161F, PHE241F, PHE245F, PHE44F, PHE585E, PHE788E, PHE798E, PHE814E, PHE815E, PRO236F, PRO33F, PRO35F, SER131F, SER261F, SER265F, SER266F, SER269F, SER32F, SER36F, SER48F, SER578E, SER582E, SER589E, SER795E, SER803E, SER842E, THR124F, THR239F, THR268F, THR574E, THR584E, THR710E, THR790E, THR804E, THR811E, TYR133F, TYR253F, TYR257F, TYR258F, TYR264F, TYR39F, TYR43F, TYR571E, TYR580E, TYR610E, TYR839E, VAL237F, VAL259F, VAL50F, VAL572E, VAL781E, VAL783E, VAL786E, VAL838E, VAL840E
• G-H: ALA255H, ALA41H, ALA802G, ARG114H, ARG163H, ARG251H, ARG281H, ARG49H, ARG55H, ARG592G, ARG794G, ARG808G, ARG812G, ASN120H, ASN126H, ASN127H, ASN234H, ASN235H, ASN243H, ASN250H, ASN42H, ASN51H, ASN54H, ASN570G, ASN590G, ASN785G, ASN7H, ASN800G, ASN818G, ASP132H, ASP238H, ASP52H, ASP587G, ASP588G, ASP784G, ASP787G, ASP807G, CYS581G, GLN229H, GLN46H, GLU125H, GLU240H, GLU247H, GLU254H, GLU38H, GLU3H, GLU612G, GLU793G, GLU806G, GLY162H, GLY40H, GLY611G, GLY704G, GLY801G, HIS260H, HIS278H, ILE117H, ILE130H, ILE166H, ILE242H, ILE47H, ILE4H, ILE577G, ILE791G, ILE792G, ILE799G, LEU128H, LEU246H, LEU256H, LEU262H, LEU263H, LEU34H, LEU37H, LEU45H, LEU53H, LEU575G, LEU576G, LEU586G, LEU708G, LEU782G, LYS111H, LYS134H, LYS244H, LYS31H, LYS573G, LYS583G, LYS591G, LYS607G, LYS706G, LYS768G, LYS796G, LYS797G, MET1H, MET579G, MET805G, PHE161H, PHE241H, PHE245H, PHE44H, PHE585G, PHE788G, PHE798G, PHE814G, PHE815G, PRO236H, PRO33H, PRO35H, SER119H, SER131H, SER261H, SER265H, SER266H, SER269H, SER32H, SER36H, SER48H, SER578G, SER582G, SER589G, SER795G, SER803G, SER842G, THR124H, THR239H, THR268H, THR574G, THR584G, THR710G, THR790G, THR804G, THR811G, TYR133H, TYR253H, TYR257H, TYR258H, TYR264H, TYR39H, TYR43H, TYR571G, TYR580G, TYR610G, TYR839G, VAL237H, VAL259H, VAL50H, VAL572G, VAL781G, VAL783G, VAL786G, VAL838G, VAL840G