2VCV

glutathione transferase a3-3 in complex with glutathione and delta-4-androstene-3-17-dione

• Total interactions analyzed: 120
• Total true interactions: 31
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 145
  • Norm. En. per Res.: -3.2273
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-27.3392	-11.2381	-404.062	-442.6393	144	18	11	15753	1	43	41
A-E	0.0	-12.0018	-93.4217	-105.4235	56	1	0	3966	0	14	12
A-L	0.0	-1.8568	-0.2197	-2.0765	4	0	0	42	0	3	7
A-O	0.0	0.7579	-13.9879	-13.23	25	2	0	961	0	13	15
A-P	-9.1599	-2.5611	-8.4317	-20.1528	19	1	0	545	0	11	10
B-K	0.0	1.5164	-10.7071	-9.1907	33	0	0	1029	0	7	12
B-L	-9.0115	-0.3951	-22.3114	-31.7181	22	4	0	1162	0	5	11
B-N	0.0	0.6978	-33.2042	-32.5064	37	0	0	2001	0	15	14
B-P	0.0	0.0	-0.0112	-0.0112	4	0	0	12	0	4	6
C-D	-15.7219	-9.9599	-404.876	-430.5578	143	10	11	15748	0	43	41
C-E	0.0	0.0	-0.0187	-0.0187	2	0	0	10	0	1	1
C-F	0.0	-5.0861	-27.2986	-32.3847	32	1	0	1215	0	11	12
C-O	0.0	-14.7187	-102.501	-117.2197	61	2	0	4325	1	14	11
D-F	0.0	-17.1877	-6.3328	-23.5204	17	0	0	393	0	6	6
E-F	-30.1882	-15.2046	-422.565	-467.9578	145	22	11	16055	2	43	42
E-O	0.0	0.0	-0.316	-0.316	9	0	0	50	0	6	7
G-H	-33.4116	-16.8814	-420.356	-470.649	147	14	11	16042	2	44	41
G-I	0.0	0.0	-0.0664	-0.0664	4	0	0	29	0	4	4
G-J	-7.4155	-24.5926	-56.5771	-88.5852	38	7	0	2162	0	18	17
H-J	-6.1355	-18.3503	-16.3627	-40.8485	22	1	0	771	2	9	7
H-K	0.0	-13.6314	-95.1368	-108.7682	60	1	0	4057	0	14	12
H-M	0.0	0.0	-0.0037	-0.0037	5	0	0	6	0	1	2
I-J	-16.3724	-13.9613	-412.462	-442.7957	149	28	11	16133	0	44	40
J-M	0.0	-12.3051	-103.164	-115.4691	62	2	0	4287	0	14	11
K-L	-41.0342	-11.4548	-401.57	-454.059	149	24	10	15765	2	44	42
K-M	0.0	0.0	-7.2477	-7.2477	19	0	0	445	0	5	4
K-N	-3.7175	2.8377	-41.6422	-42.522	35	3	0	2083	0	9	10
L-N	-6.8577	5.8753	-13.7037	-14.6862	26	0	0	739	0	8	7
L-P	0.0	1.0604	-33.9766	-32.9162	42	1	0	2036	0	14	14
M-N	-2.3232	-14.7032	-406.547	-423.5734	146	20	11	16054	0	43	41
O-P	-11.8704	-18.387	-415.28	-445.5374	145	27	11	16224	2	43	41

Interface residues

• A-B: ALA100A, ALA100B, ALA135A, ALA135B, ALA70A, ALA70B, ALA76A, ALA76B, ALA90A, ALA90B, ARG113A, ARG113B, ARG131A, ARG131B, ARG155A, ARG155B, ARG15A, ARG45A, ARG45B, ARG69A, ARG69B, ARG89A, ARG89B, ASN73A, ASN73B, ASN80A, ASN80B, ASP101A, ASP101B, ASP47A, ASP47B, ASP61A, ASP61B, ASP85A, ASP85B, ASP93A, ASP93B, GLN53A, GLN53B, GLN54A, GLN54B, GLN67A, GLN67B, GLU104A, GLU116A, GLU126A, GLU126B, GLU137A, GLU137B, GLU88A, GLU88B, GLU97A, GLU97B, GLY48A, GLY48B, GLY62A, GLY62B, GLY98A, GLY98B, ILE60A, ILE60B, ILE71A, ILE71B, ILE75A, ILE75B, ILE86A, ILE86B, ILE92A, ILE92B, LEU102A, LEU102B, LEU140A, LEU140B, LEU148A, LEU148B, LEU160A, LEU160B, LEU41A, LEU41B, LEU50A, LEU50B, LEU65A, LEU65B, LEU72A, LEU72B, LEU91A, LEU91B, LYS127A, LYS127B, LYS129A, LYS138A, LYS138B, LYS64A, LYS64B, LYS78A, LYS78B, LYS87A, LYS87B, MET105A, MET51A, MET51B, MET57A, MET57B, MET63A, MET63B, MET94A, MET94B, MET99A, MET99B, PHE133A, PHE133B, PHE136A, PHE136B, PHE52A, PHE52B, PRO134A, PRO134B, SER130A, SER130B, SER49A, SER49B, SER77A, SER77B, THR68A, THR68B, THR96A, THR96B, TYR132A, TYR132B, TYR74A, TYR74B, TYR79A, TYR79B, TYR82A, TYR82B, TYR95A, TYR95B, VAL139A, VAL139B, VAL149B, VAL55A, VAL55B, VAL66A, VAL66B
• A-E: ALA208A, ALA210E, ARG13A, ARG13E, ARG204A, ARG204E, ASN11A, ASN11E, ASN190A, ASP171E, ASP209A, ASP209E, GLN199A, GLN199E, GLU168A, GLU168E, GLU169A, GLU169E, GLU17A, GLU17E, GLU29A, GLU29E, GLY201A, GLY201E, LEU170A, LEU170E, LEU198A, LEU198E, LYS195A, LYS195E, LYS196A, LYS196E, LYS205A, LYS205E, LYS211A, LYS211E, LYS4A, LYS4E, PHE197A, PHE197E, PRO200A, PRO200E, PRO203A, PRO203E, PRO206A, PRO206E, PRO207A, PRO207E, SER172E, SER202A, SER202E, TRP21A, TRP21E, TYR165E, TYR166A, TYR166E
• A-L: ASN46A, ASP47A, GLY48A, LYS4L
• A-O: ALA38A, ALA90O, ASN46A, ASP40A, ASP85O, GLN141O, GLU214A, GLU215A, GLU39A, GLU88O, GLY144O, GLY42A, HIS143O, ILE86O, LEU140O, LEU91O, LYS138O, LYS211A, LYS218A, LYS43A, LYS84O, LYS87O, SER142O, SER37A, VAL139O
• A-P: ALA38A, ARG221A, ARG45A, ASN46A, ASP47P, ASP61P, GLU39A, GLU59P, GLY42A, GLY48P, GLY62P, ILE60P, LEU65P, LYS218A, LYS64P, LYS78P, MET63P, SER49P, TYR74P
• B-K: ALA183B, ARG187B, ASN151B, ASN151K, ASN177B, ASP146B, ASP85K, GLN141B, GLN141K, GLN145B, GLN145K, GLU137B, GLU88K, GLY144B, GLY144K, GLY150K, HIS143B, HIS143K, LEU180B, LEU184B, LEU91K, LYS138B, LYS138K, LYS182B, LYS84K, LYS87K, PHE178B, PRO134B, PRO179B, SER142K, SER176B, THR186B, VAL149K
• B-L: ASN151B, ASN46L, ASP47L, ASP61L, GLN141B, GLN145B, GLU137B, GLU59L, GLY144B, GLY48L, GLY62L, HIS143B, ILE60L, LEU140B, LEU180B, LYS138B, LYS64L, MET63L, PRO134B, SER142B, SER49L, VAL139B
• B-N: ALA26B, ARG187B, ARG187N, ASN151B, ASN151N, ASN190B, ASN190N, ASN80B, ASN80N, ASP146B, ASP146N, ASP85B, ASP85N, GLN145B, GLN145N, GLY144B, GLY144N, GLY150B, GLY150N, GLY27B, GLY27N, GLY83B, GLY83N, LEU153B, LEU153N, LEU191B, LEU191N, LYS152B, LYS152N, LYS84B, LYS84N, PRO192B, PRO192N, THR193B, THR193N, TYR147B, TYR147N
• B-P: GLU126B, GLU31P, LYS129B, LYS4P
• C-D: ALA100C, ALA100D, ALA135C, ALA135D, ALA70C, ALA70D, ALA76C, ALA76D, ALA90C, ALA90D, ARG131C, ARG131D, ARG155C, ARG155D, ARG15C, ARG15D, ARG221D, ARG45C, ARG45D, ARG69C, ARG69D, ARG89C, ARG89D, ASN73C, ASN73D, ASN80C, ASN80D, ASP101C, ASP101D, ASP47C, ASP47D, ASP61C, ASP61D, ASP85C, ASP85D, ASP93C, ASP93D, GLN53C, GLN53D, GLN54C, GLN54D, GLN67C, GLN67D, GLU126D, GLU137C, GLU137D, GLU88C, GLU88D, GLU97C, GLU97D, GLY48C, GLY48D, GLY62C, GLY62D, GLY98C, GLY98D, ILE60C, ILE60D, ILE71C, ILE71D, ILE75C, ILE75D, ILE86C, ILE86D, ILE92C, ILE92D, LEU102C, LEU102D, LEU140C, LEU140D, LEU148C, LEU148D, LEU160C, LEU160D, LEU163C, LEU41C, LEU41D, LEU50C, LEU50D, LEU65C, LEU65D, LEU72C, LEU72D, LEU91C, LEU91D, LYS127C, LYS127D, LYS138C, LYS138D, LYS64C, LYS64D, LYS78C, LYS78D, LYS87C, LYS87D, MET105C, MET105D, MET51C, MET51D, MET57C, MET57D, MET63C, MET63D, MET94C, MET94D, MET99C, MET99D, PHE133C, PHE133D, PHE136C, PHE136D, PHE52C, PHE52D, PRO134C, PRO134D, SER130C, SER130D, SER142D, SER49C, SER49D, SER77C, SER77D, THR68C, THR68D, THR96C, THR96D, TYR132C, TYR132D, TYR74C, TYR74D, TYR79C, TYR79D, TYR82C, TYR82D, TYR95C, TYR95D, VAL139C, VAL139D, VAL149C, VAL55C, VAL55D, VAL66C, VAL66D
• C-E: GLY62E, SER173C
• C-F: ALA119C, ALA122C, ARG131C, ASN151F, ASN177C, ASP118C, ASP85F, GLN141F, GLN145F, GLU116C, GLU126C, GLU88F, GLY144F, GLY150F, HIS143F, ILE121C, ILE124C, LEU123C, LEU140F, LEU91F, LYS120C, LYS125C, LYS127C, LYS129C, LYS138F, LYS84F, LYS87F, SER130C, SER142F, SER173C, SER176C, VAL139F
• C-O: ALA208O, ALA210C, ALA212C, ARG13C, ARG13O, ARG204C, ARG204O, ASN11C, ASN11O, ASN190O, ASP171C, ASP209C, ASP209O, GLN199C, GLN199O, GLU168C, GLU168O, GLU169C, GLU169O, GLU17C, GLU17O, GLU29C, GLU29O, GLY12C, GLY201C, GLY201O, LEU170C, LEU170O, LEU198C, LEU198O, LYS195C, LYS195O, LYS196C, LYS196O, LYS205C, LYS205O, LYS211C, LYS211O, LYS4C, LYS4O, PHE197C, PHE197O, PRO200C, PRO200O, PRO203C, PRO203O, PRO206C, PRO206O, PRO207C, PRO207O, SER172C, SER202C, SER202O, THR186O, TRP21C, TRP21O, TYR165C, TYR165O, TYR166C, TYR166O, VAL167C
• D-F: ALA183F, ALA38D, ARG187F, ARG221D, ARG45D, ASN151F, ASN190F, ASN46D, ASP146F, GLN145F, GLN53D, GLU39D, GLY144F, GLY42D, LEU180F, LEU184F, THR186F
• E-F: ALA100E, ALA100F, ALA135E, ALA135F, ALA156E, ALA70E, ALA70F, ALA76E, ALA76F, ALA90E, ALA90F, ARG113E, ARG113F, ARG131E, ARG131F, ARG155E, ARG155F, ARG15E, ARG15F, ARG45E, ARG45F, ARG69E, ARG69F, ARG89E, ARG89F, ASN73E, ASN73F, ASN80E, ASN80F, ASP101E, ASP101F, ASP47E, ASP61E, ASP61F, ASP85E, ASP85F, ASP93E, ASP93F, GLN53E, GLN53F, GLN54E, GLN54F, GLN67E, GLN67F, GLU104E, GLU126E, GLU126F, GLU137E, GLU137F, GLU88E, GLU88F, GLU97E, GLU97F, GLY48E, GLY48F, GLY62E, GLY62F, GLY98E, GLY98F, ILE60E, ILE60F, ILE71E, ILE71F, ILE75E, ILE75F, ILE86E, ILE86F, ILE92E, ILE92F, LEU102E, LEU102F, LEU140E, LEU140F, LEU148E, LEU148F, LEU160E, LEU160F, LEU163E, LEU41E, LEU41F, LEU50E, LEU50F, LEU65E, LEU65F, LEU72E, LEU72F, LEU91E, LEU91F, LYS127E, LYS127F, LYS138E, LYS138F, LYS64E, LYS64F, LYS78E, LYS78F, LYS87E, LYS87F, MET105E, MET105F, MET51E, MET51F, MET57E, MET57F, MET63E, MET63F, MET94E, MET94F, MET99E, MET99F, PHE133E, PHE133F, PHE136E, PHE136F, PHE52E, PHE52F, PRO134E, PRO134F, SER130E, SER130F, SER49E, SER77E, SER77F, THR68E, THR68F, THR96E, THR96F, TYR132E, TYR132F, TYR74E, TYR74F, TYR79E, TYR79F, TYR82E, TYR82F, TYR95E, TYR95F, VAL139E, VAL139F, VAL149E, VAL149F, VAL55E, VAL55F, VAL66E, VAL66F
• E-O: ARG187O, ASP146O, GLN141O, GLN145O, GLU29E, GLU31E, GLY144O, LEU180O, LYS4E
• G-H: ALA100G, ALA100H, ALA135G, ALA135H, ALA70G, ALA70H, ALA76G, ALA76H, ALA90G, ALA90H, ARG113G, ARG113H, ARG131G, ARG131H, ARG155G, ARG155H, ARG15H, ARG221G, ARG45G, ARG45H, ARG69G, ARG69H, ARG89G, ARG89H, ASN46H, ASN73G, ASN73H, ASN80G, ASN80H, ASP101G, ASP101H, ASP47H, ASP61G, ASP61H, ASP85G, ASP85H, ASP93G, ASP93H, GLN53G, GLN53H, GLN54G, GLN54H, GLN67G, GLN67H, GLU104H, GLU116G, GLU126G, GLU126H, GLU137G, GLU137H, GLU88G, GLU88H, GLU97G, GLU97H, GLY48G, GLY48H, GLY62G, GLY62H, GLY98G, GLY98H, ILE60G, ILE60H, ILE71G, ILE71H, ILE75G, ILE75H, ILE86G, ILE86H, ILE92G, ILE92H, LEU102G, LEU102H, LEU140G, LEU140H, LEU148G, LEU148H, LEU160G, LEU160H, LEU41G, LEU41H, LEU50G, LEU50H, LEU65G, LEU65H, LEU72G, LEU72H, LEU91G, LEU91H, LYS127G, LYS127H, LYS129H, LYS138G, LYS138H, LYS64G, LYS64H, LYS78G, LYS78H, LYS87G, LYS87H, MET105G, MET105H, MET51G, MET51H, MET57G, MET57H, MET63G, MET63H, MET94G, MET94H, MET99G, MET99H, PHE133G, PHE133H, PHE136G, PHE136H, PHE220G, PHE52G, PHE52H, PRO134G, PRO134H, SER130G, SER130H, SER49H, SER77G, SER77H, THR68G, THR68H, THR96G, THR96H, TYR132G, TYR132H, TYR74G, TYR74H, TYR79G, TYR79H, TYR82G, TYR82H, TYR95G, TYR95H, VAL139G, VAL139H, VAL149G, VAL149H, VAL55G, VAL55H, VAL66G, VAL66H
• G-I: GLU126I, LYS127I, LYS43G, SER130I
• G-J: ALA38J, ARG217J, ARG221J, ARG45G, ARG45J, ASN46G, ASN46J, ASP40J, ASP47G, ASP47J, ASP61G, GLN53G, GLU39J, GLU59G, GLY42G, GLY42J, GLY48G, GLY48J, GLY62G, HIS8G, ILE219J, ILE60G, LEU41J, LEU44G, LEU50G, LEU65G, LYS218J, LYS43G, LYS43J, LYS64G, LYS6G, MET51G, MET57G, MET63G, PHE220J, PHE52G, SER37J, SER49G
• H-J: ALA135H, ALA38J, ARG221J, ASP40J, ASP47J, GLN141H, GLU39J, GLY36J, HIS143H, ILE219J, LEU91H, LYS138H, LYS218J, LYS33J, LYS43J, LYS87H, PHE34J, PRO134H, SER142H, SER37J, TYR95H, VAL139H
• H-K: ALA208H, ALA208K, ALA210H, ARG13H, ARG13K, ARG204H, ARG204K, ASN11H, ASN11K, ASN190K, ASP171H, ASP209H, ASP209K, GLN199H, GLN199K, GLU168H, GLU168K, GLU169H, GLU169K, GLU17H, GLU17K, GLU29H, GLU29K, GLY12H, GLY12K, GLY201H, GLY201K, LEU170H, LEU170K, LEU198H, LEU198K, LYS195H, LYS195K, LYS196H, LYS196K, LYS205H, LYS205K, LYS211H, LYS211K, LYS4K, PHE197H, PHE197K, PRO200H, PRO200K, PRO203H, PRO203K, PRO206H, PRO206K, PRO207H, PRO207K, SER172H, SER172K, SER202H, SER202K, TRP21H, TRP21K, TYR165H, TYR165K, TYR166H, TYR166K
• H-M: ARG187H, GLU31M, LYS43M, PRO179H, THR186H
• I-J: ALA100I, ALA100J, ALA135I, ALA135J, ALA156I, ALA156J, ALA70I, ALA70J, ALA76I, ALA76J, ALA90I, ALA90J, ARG113I, ARG113J, ARG131I, ARG131J, ARG155I, ARG155J, ARG15J, ARG45I, ARG45J, ARG69I, ARG69J, ARG89I, ARG89J, ASN46I, ASN73I, ASN73J, ASN80I, ASN80J, ASP101I, ASP101J, ASP47I, ASP47J, ASP61I, ASP61J, ASP85I, ASP85J, ASP93I, ASP93J, GLN53I, GLN53J, GLN54I, GLN54J, GLN67I, GLN67J, GLU116I, GLU126I, GLU126J, GLU137I, GLU137J, GLU88I, GLU88J, GLU97I, GLU97J, GLY48I, GLY48J, GLY62I, GLY62J, GLY98I, GLY98J, ILE60I, ILE60J, ILE71I, ILE71J, ILE75I, ILE75J, ILE86I, ILE86J, ILE92I, ILE92J, LEU102I, LEU102J, LEU140I, LEU140J, LEU148I, LEU148J, LEU160I, LEU160J, LEU41I, LEU50I, LEU50J, LEU65I, LEU65J, LEU72I, LEU72J, LEU91I, LEU91J, LYS127I, LYS127J, LYS129I, LYS138I, LYS138J, LYS64I, LYS64J, LYS78I, LYS78J, LYS87I, LYS87J, MET105I, MET105J, MET51I, MET51J, MET57I, MET57J, MET63I, MET63J, MET94I, MET94J, MET99I, MET99J, PHE133I, PHE133J, PHE136I, PHE136J, PHE52I, PHE52J, PRO134I, PRO134J, PRO56J, SER130I, SER130J, SER142J, SER49I, SER49J, SER77I, SER77J, THR68I, THR68J, THR96I, THR96J, TYR132I, TYR132J, TYR74I, TYR74J, TYR79I, TYR79J, TYR82I, TYR82J, TYR95I, TYR95J, VAL139I, VAL139J, VAL149J, VAL55I, VAL55J, VAL58J, VAL66I, VAL66J
• J-M: ALA208J, ALA208M, ALA210J, ALA212J, ARG13J, ARG13M, ARG204J, ARG204M, ASN11J, ASN11M, ASN190M, ASP171J, ASP209J, ASP209M, GLN199J, GLN199M, GLU168J, GLU168M, GLU169J, GLU169M, GLU17J, GLU17M, GLU29J, GLU29M, GLY12J, GLY201J, GLY201M, LEU170J, LEU170M, LEU198J, LEU198M, LYS195J, LYS195M, LYS196J, LYS196M, LYS205J, LYS205M, LYS211J, LYS211M, LYS4J, LYS4M, PHE197J, PHE197M, PRO200J, PRO200M, PRO203J, PRO203M, PRO206J, PRO206M, PRO207J, PRO207M, SER172J, SER202J, SER202M, THR186M, TRP21J, TRP21M, TYR165J, TYR165M, TYR166J, TYR166M, VAL167J
• K-L: ALA100K, ALA100L, ALA135K, ALA135L, ALA156L, ALA70K, ALA70L, ALA76K, ALA76L, ALA90K, ALA90L, ARG113K, ARG113L, ARG131K, ARG131L, ARG155K, ARG155L, ARG15K, ARG15L, ARG45K, ARG45L, ARG69K, ARG69L, ARG89K, ARG89L, ASN73K, ASN73L, ASN80K, ASN80L, ASP101K, ASP101L, ASP47K, ASP47L, ASP61K, ASP61L, ASP85K, ASP85L, ASP93K, ASP93L, GLN53K, GLN53L, GLN54K, GLN54L, GLN67K, GLN67L, GLU104K, GLU104L, GLU116K, GLU126K, GLU126L, GLU137K, GLU137L, GLU88K, GLU88L, GLU97K, GLU97L, GLY48K, GLY48L, GLY62K, GLY62L, GLY98K, GLY98L, ILE60K, ILE60L, ILE71K, ILE71L, ILE75K, ILE75L, ILE86K, ILE86L, ILE92K, ILE92L, LEU102K, LEU102L, LEU140K, LEU140L, LEU148K, LEU148L, LEU160K, LEU160L, LEU163L, LEU41K, LEU41L, LEU50K, LEU50L, LEU65K, LEU65L, LEU72K, LEU72L, LEU91K, LEU91L, LYS127K, LYS127L, LYS129K, LYS138K, LYS138L, LYS64K, LYS64L, LYS78K, LYS78L, LYS87K, LYS87L, MET105K, MET105L, MET51K, MET51L, MET57K, MET57L, MET63K, MET63L, MET94K, MET94L, MET99K, MET99L, PHE133K, PHE133L, PHE136K, PHE136L, PHE220K, PHE52K, PHE52L, PRO134K, PRO134L, SER130K, SER130L, SER49K, SER49L, SER77K, SER77L, THR68K, THR68L, THR96K, THR96L, TYR132K, TYR132L, TYR74K, TYR74L, TYR79K, TYR79L, TYR82K, TYR82L, TYR95K, TYR95L, VAL139K, VAL139L, VAL55K, VAL55L, VAL66K, VAL66L
• K-M: ARG45M, ASN177K, ASN46M, ASP171K, ASP47M, GLY48M, GLY62M, LEU174K, LYS125K, LYS129K, LYS182K, LYS43M, LYS64M, MET51M, PRO179K, SER172K, SER173K, SER176K, SER49M
• K-N: ALA135K, ARG131K, ASN151N, ASN177K, ASP146N, GLN141K, GLN141N, GLN145N, GLU126K, GLU137K, GLU137N, GLY144N, HIS143N, LEU140N, LEU174K, LEU180N, LYS127K, LYS129K, LYS138K, LYS138N, LYS84N, MET94N, PHE133K, PHE178K, PRO134K, PRO179K, PRO179N, SER130K, SER142K, SER142N, SER173K, SER176K, THR128K, TYR132K, VAL139N
• L-N: ALA183N, ARG187N, ARG221L, ARG45L, ASN46L, ASP146N, ASP47L, GLN141N, GLN145N, GLN53L, GLU137N, GLU39L, GLY144N, GLY42L, GLY48L, LEU140N, LEU180N, LEU181N, LEU184N, LYS182N, LYS43L, MET51L, PHE178N, PRO179N, SER176N, THR186N
• L-P: ALA26L, ALA26P, ARG187L, ARG187P, ASN151L, ASN151P, ASN190L, ASN190P, ASN80L, ASN80P, ASP146L, ASP146P, ASP85L, ASP85P, GLN145L, GLN145P, GLU88P, GLY144L, GLY144P, GLY150L, GLY150P, GLY27L, GLY27P, GLY83L, GLY83P, LEU153L, LEU153P, LEU191L, LEU191P, LEU81P, LYS152L, LYS152P, LYS84L, LYS84P, PRO192L, PRO192P, THR193L, THR193P, TYR147L, TYR147P, TYR79L, TYR79P
• M-N: ALA100M, ALA100N, ALA135M, ALA135N, ALA156N, ALA70M, ALA70N, ALA76M, ALA76N, ALA90M, ALA90N, ARG113M, ARG113N, ARG131M, ARG131N, ARG155M, ARG155N, ARG15N, ARG221M, ARG45M, ARG45N, ARG69M, ARG69N, ARG89M, ARG89N, ASN73M, ASN73N, ASN80M, ASN80N, ASP101M, ASP101N, ASP47M, ASP47N, ASP61M, ASP61N, ASP85M, ASP85N, ASP93M, ASP93N, GLN53M, GLN53N, GLN54M, GLN54N, GLN67M, GLN67N, GLU116M, GLU126M, GLU126N, GLU137M, GLU137N, GLU88M, GLU88N, GLU97M, GLU97N, GLY48M, GLY48N, GLY62M, GLY62N, GLY98M, GLY98N, ILE60M, ILE60N, ILE71M, ILE71N, ILE75M, ILE75N, ILE86M, ILE86N, ILE92M, ILE92N, LEU102M, LEU102N, LEU140M, LEU140N, LEU148M, LEU148N, LEU160M, LEU160N, LEU41M, LEU41N, LEU50M, LEU50N, LEU65M, LEU65N, LEU72M, LEU72N, LEU91M, LEU91N, LYS127M, LYS127N, LYS138M, LYS138N, LYS64M, LYS64N, LYS78M, LYS78N, LYS87M, LYS87N, MET105M, MET105N, MET51M, MET51N, MET57M, MET57N, MET63M, MET63N, MET94M, MET94N, MET99M, MET99N, PHE133M, PHE133N, PHE136M, PHE136N, PHE220M, PHE52M, PHE52N, PRO134M, PRO134N, SER130M, SER130N, SER49M, SER49N, SER77M, SER77N, THR68M, THR68N, THR96M, THR96N, TYR132M, TYR132N, TYR74M, TYR74N, TYR79M, TYR79N, TYR82M, TYR82N, TYR95M, TYR95N, VAL139M, VAL139N, VAL149N, VAL55M, VAL55N, VAL66M, VAL66N
• O-P: ALA100O, ALA100P, ALA135O, ALA135P, ALA156P, ALA70O, ALA70P, ALA76O, ALA76P, ALA90O, ALA90P, ARG131O, ARG131P, ARG155O, ARG155P, ARG15P, ARG221P, ARG45O, ARG45P, ARG69O, ARG69P, ARG89O, ARG89P, ASN73O, ASN73P, ASN80O, ASN80P, ASP101O, ASP101P, ASP47O, ASP47P, ASP61O, ASP61P, ASP85O, ASP85P, ASP93O, ASP93P, GLN53O, GLN53P, GLN54O, GLN54P, GLN67O, GLN67P, GLU104P, GLU126O, GLU126P, GLU137O, GLU137P, GLU88O, GLU88P, GLU97O, GLU97P, GLY48O, GLY48P, GLY62O, GLY62P, GLY98O, GLY98P, ILE60O, ILE60P, ILE71O, ILE71P, ILE75O, ILE75P, ILE86O, ILE86P, ILE92O, ILE92P, LEU102O, LEU102P, LEU140O, LEU140P, LEU148O, LEU148P, LEU160O, LEU160P, LEU41O, LEU41P, LEU50O, LEU50P, LEU65O, LEU65P, LEU72O, LEU72P, LEU91O, LEU91P, LYS127O, LYS127P, LYS138O, LYS138P, LYS64O, LYS64P, LYS78O, LYS78P, LYS87O, LYS87P, MET105O, MET105P, MET51O, MET51P, MET57O, MET57P, MET63O, MET63P, MET94O, MET94P, MET99O, MET99P, PHE133O, PHE133P, PHE136O, PHE136P, PHE220O, PHE52O, PHE52P, PRO134O, PRO134P, PRO56P, SER130O, SER130P, SER49O, SER49P, SER77O, SER77P, THR68O, THR68P, THR96O, THR96P, TYR132O, TYR132P, TYR74O, TYR74P, TYR79O, TYR79P, TYR82O, TYR82P, TYR95O, TYR95P, VAL139O, VAL139P, VAL149P, VAL55O, VAL58P, VAL66O, VAL66P