2V6L

molecular model of a type iii secretion system needle

• Total interactions analyzed: 378
• Total true interactions: 62
• Strongest Interaction:
  • Chains: P-V
  • Int. Res.: 13
  • Norm. En. per Res.: -0.1568
• Hub Node: 1(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
0-P	0.0	0.0	-0.665	-0.665	14	0	0	160	0	0	0
0-U	0.0	0.0	-2.0311	-2.0311	14	0	0	234	0	0	0
0-V	0.0	0.0	-4.0248	-4.0248	60	5	0	988	0	0	0
1-Q	0.0	0.0	-0.6548	-0.6548	12	0	0	153	0	0	0
1-V	0.0	0.0	-2.0551	-2.0551	14	0	0	227	0	0	0
1-W	0.0	0.0	-6.7817	-6.7817	57	3	0	985	0	0	0
A-F	0.0	0.0	-4.0769	-4.0769	60	5	0	988	0	0	0
A-G	0.0	0.0	-2.0473	-2.0473	14	0	0	224	0	0	0
A-L	0.0	0.0	-0.6472	-0.6472	14	0	0	162	0	0	0
B-G	0.0	0.0	-6.8056	-6.8056	57	3	0	985	0	0	0
B-H	0.0	0.0	-2.0359	-2.0359	13	0	0	226	0	0	0
B-M	0.0	0.0	-0.6648	-0.6648	14	0	0	160	0	0	0
C-H	0.0	0.0	-5.4976	-5.4976	60	3	0	985	0	0	0
C-I	0.0	0.0	-2.0236	-2.0236	13	0	0	238	0	0	0
C-N	0.0	0.0	-0.6548	-0.6548	12	0	0	153	0	0	0
D-I	0.0	0.0	-3.265	-3.265	59	5	0	1006	0	0	0
D-J	0.0	0.0	-2.0366	-2.0366	14	0	0	227	0	0	0
D-O	0.0	0.0	-0.6387	-0.6387	14	0	0	157	0	0	0
E-J	0.0	0.0	-5.5073	-5.5073	59	3	0	981	0	0	0
E-K	0.0	0.0	-2.048	-2.048	14	0	0	226	0	0	0
E-P	0.0	0.0	-0.6514	-0.6514	13	0	0	161	0	0	0
F-K	0.0	0.0	-6.7167	-6.7167	58	3	0	991	0	0	0
F-L	0.0	0.0	-2.0226	-2.0226	13	0	0	226	0	0	0
F-Q	0.0	0.0	-0.6688	-0.6688	13	0	0	155	0	0	0
G-L	0.0	0.0	-3.9507	-3.9507	60	4	0	980	0	0	0
G-M	0.0	0.0	-2.0287	-2.0287	14	0	0	232	0	0	0
G-R	0.0	0.0	-0.6497	-0.6497	15	0	0	159	0	0	0
H-M	0.0	0.0	-4.0398	-4.0398	60	5	0	988	0	0	0
H-N	0.0	0.0	-2.0486	-2.0486	14	0	0	224	0	0	0
H-S	0.0	0.0	-0.6474	-0.6474	14	0	0	162	0	0	0
I-N	0.0	0.0	-6.7843	-6.7843	57	3	0	983	0	0	0
I-O	0.0	0.0	-2.0376	-2.0376	13	0	0	226	0	0	0
I-T	0.0	0.0	-0.6649	-0.6649	14	0	0	160	0	0	0
J-O	0.0	0.0	-5.4838	-5.4838	60	3	0	991	0	0	0
J-P	0.0	0.0	-2.0256	-2.0256	13	0	0	238	0	0	0
J-U	0.0	0.0	-0.6547	-0.6547	12	0	0	153	0	0	0
K-P	0.0	0.0	-3.2123	-3.2123	59	5	0	1007	0	0	0
K-Q	0.0	0.0	-2.0383	-2.0383	14	0	0	227	0	0	0
K-V	0.0	0.0	-0.6385	-0.6385	14	0	0	157	0	0	0
L-Q	0.0	0.0	-5.4562	-5.4562	59	3	0	981	0	0	0
L-R	0.0	0.0	-2.0489	-2.0489	14	0	0	226	0	0	0
L-W	0.0	0.0	-0.6512	-0.6512	13	0	0	161	0	0	0
M-R	0.0	0.0	-6.7138	-6.7138	58	3	0	991	0	0	0
M-S	0.0	0.0	-2.0245	-2.0245	13	0	0	226	0	0	0
M-X	0.0	0.0	-0.6685	-0.6685	13	0	0	155	0	0	0
N-S	0.0	0.0	-3.9536	-3.9536	60	4	0	978	0	0	0
N-T	0.0	0.0	-2.0303	-2.0303	14	0	0	234	0	0	0
N-Y	0.0	0.0	-0.65	-0.65	15	0	0	159	0	0	0
O-T	0.0	0.0	-4.0143	-4.0143	60	5	0	988	0	0	0
O-U	0.0	0.0	-2.0501	-2.0501	14	0	0	225	0	0	0
O-Z	0.0	0.0	-0.6478	-0.6478	14	0	0	162	0	0	0
P-U	0.0	0.0	-6.7732	-6.7732	57	3	0	985	0	0	0
P-V	0.0	0.0	-2.0384	-2.0384	13	0	0	226	0	0	0
Q-V	0.0	0.0	-5.5087	-5.5087	60	3	0	989	0	0	0
Q-W	0.0	0.0	-2.0265	-2.0265	13	0	0	238	0	0	0
R-W	0.0	0.0	-3.2126	-3.2126	59	5	0	1006	0	0	0
R-X	0.0	0.0	-2.04	-2.04	14	0	0	227	0	0	0
S-X	0.0	0.0	-5.4264	-5.4264	59	3	0	979	0	0	0
S-Y	0.0	0.0	-2.0509	-2.0509	14	0	0	226	0	0	0
T-Y	0.0	0.0	-6.7047	-6.7047	58	3	0	990	0	0	0
T-Z	0.0	0.0	-2.0259	-2.0259	13	0	0	226	0	0	0
U-Z	0.0	0.0	-3.9636	-3.9636	60	4	0	978	0	0	0

Interface residues

• 0-P: ALA38P, ALA770, ASN810, ASP35P, ASP730, GLN27P, GLN800, GLY28P, ILE780, LEU30P, LEU32P, LEU34P, PHE820, THR31P
• 0-U: ASN70, ASP20U, ASP21U, ASP80, ASP90, GLN24U, GLY22U, PHE19U, PRO60, THR23U, THR25U, THR40, VAL30, VAL50
• 0-V: ALA33V, ALA630, ALA63V, ALA760, ARG610, ASN620, ASN660, ASN70, ASP21V, ASP35V, ASP730, ASP750, ASP80, ASP90, GLN24V, GLN27V, GLN640, GLU17V, GLU29V, GLU49V, GLU56V, GLY22V, GLY28V, ILE710, ILE790, LEU120, LEU15V, LEU26V, LEU30V, LEU32V, LEU34V, LEU54V, LEU59V, LYS36V, LYS53V, LYS690, LYS720, PHE19V, PHE820, PRO60, SER130, SER140, SER160, SER52V, SER55V, SER650, THR110, THR18V, THR23V, THR25V, THR31V, THR40, THR670, THR67V, TRP100, TYR50V, TYR57V, TYR60V, VAL30, VAL680
• 1-Q: ALA38Q, ALA771, ASN811, ASP35Q, GLN27Q, GLN801, ILE781, LEU30Q, LEU32Q, LEU34Q, PHE821, THR31Q
• 1-V: ASN71, ASP20V, ASP21V, ASP81, ASP91, GLN24V, GLY22V, PHE19V, PRO61, THR23V, THR25V, THR41, VAL31, VAL51
• 1-W: ALA33W, ALA631, ALA63W, ALA761, ARG611, ASN621, ASN661, ASN71, ASP21W, ASP35W, ASP731, ASP751, ASP91, GLN24W, GLN27W, GLN641, GLU17W, GLU29W, GLU49W, GLU56W, GLY22W, GLY28W, ILE711, ILE781, ILE791, LEU121, LEU15W, LEU26W, LEU30W, LEU32W, LEU34W, LEU54W, LEU59W, LYS36W, LYS53W, LYS691, LYS721, PHE19W, PRO61, SER131, SER161, SER52W, SER55W, SER651, THR111, THR18W, THR23W, THR25W, THR31W, THR41, THR671, TRP101, TYR50W, TYR57W, TYR60W, VAL31, VAL681
• A-F: ALA33A, ALA63A, ALA63F, ALA76F, ARG61F, ASN62F, ASN66F, ASN7F, ASP21A, ASP35A, ASP73F, ASP75F, ASP8F, ASP9F, GLN24A, GLN27A, GLN64F, GLU17A, GLU29A, GLU49A, GLU56A, GLY22A, GLY28A, ILE71F, ILE79F, LEU12F, LEU15A, LEU26A, LEU30A, LEU32A, LEU34A, LEU54A, LEU59A, LYS36A, LYS53A, LYS69F, LYS72F, PHE19A, PHE82F, PRO6F, SER13F, SER14F, SER16F, SER52A, SER55A, SER65F, THR11F, THR18A, THR23A, THR25A, THR31A, THR4F, THR67A, THR67F, TRP10F, TYR50A, TYR57A, TYR60A, VAL3F, VAL68F
• A-G: ASN7G, ASP20A, ASP21A, ASP8G, ASP9G, GLN24A, GLY22A, PHE19A, PRO6G, THR23A, THR25A, THR4G, VAL3G, VAL5G
• A-L: ALA38A, ALA76L, ALA77L, ASN81L, ASP35A, ASP73L, GLN27A, GLN80L, GLY28A, ILE78L, LEU30A, LEU34A, PHE82L, THR31A
• B-G: ALA33B, ALA63B, ALA63G, ALA76G, ARG61G, ASN62G, ASN66G, ASN7G, ASP21B, ASP35B, ASP73G, ASP75G, ASP9G, GLN24B, GLN27B, GLN64G, GLU17B, GLU29B, GLU49B, GLU56B, GLY22B, GLY28B, ILE71G, ILE78G, ILE79G, LEU12G, LEU15B, LEU26B, LEU30B, LEU32B, LEU34B, LEU54B, LEU59B, LYS36B, LYS53B, LYS69G, LYS72G, PHE19B, PRO6G, SER13G, SER16G, SER52B, SER55B, SER65G, THR11G, THR18B, THR23B, THR25B, THR31B, THR4G, THR67G, TRP10G, TYR50B, TYR57B, TYR60B, VAL3G, VAL68G
• B-H: ASN7H, ASP20B, ASP21B, ASP8H, ASP9H, GLN24B, GLY22B, PHE19B, PRO6H, THR23B, THR4H, VAL3H, VAL5H
• B-M: ALA38B, ALA77M, ASN81M, ASP35B, ASP73M, GLN27B, GLN80M, GLY28B, ILE78M, LEU30B, LEU32B, LEU34B, PHE82M, THR31B
• C-H: ALA33C, ALA63C, ALA63H, ALA76H, ARG61H, ASN62H, ASN66H, ASN7H, ASP21C, ASP35C, ASP73H, ASP75H, ASP9H, GLN24C, GLN27C, GLN64H, GLU17C, GLU29C, GLU49C, GLU56C, GLY22C, GLY28C, ILE71H, ILE78H, ILE79H, LEU12H, LEU15C, LEU26C, LEU30C, LEU32C, LEU34C, LEU59C, LYS36C, LYS53C, LYS69H, LYS72H, PHE19C, PHE82H, PRO6H, SER13H, SER14H, SER16H, SER52C, SER55C, SER65H, THR11H, THR18C, THR23C, THR25C, THR31C, THR4H, THR67C, THR67H, TRP10H, TYR50C, TYR57C, TYR60C, VAL3H, VAL68H, VAL70H
• C-I: ASN7I, ASP20C, ASP21C, ASP8I, ASP9I, GLN24C, GLY22C, PHE19C, PRO6I, THR23C, THR4I, VAL3I, VAL5I
• C-N: ALA38C, ALA77N, ASN81N, ASP35C, GLN27C, GLN80N, ILE78N, LEU30C, LEU32C, LEU34C, PHE82N, THR31C
• D-I: ALA33D, ALA63D, ALA63I, ALA76I, ARG61I, ASN62I, ASN66I, ASN7I, ASP21D, ASP35D, ASP73I, ASP75I, ASP9I, GLN24D, GLN27D, GLN64I, GLU17D, GLU29D, GLU49D, GLU56D, GLY22D, GLY28D, ILE71I, ILE79I, LEU12I, LEU15D, LEU26D, LEU30D, LEU32D, LEU34D, LEU59D, LYS36D, LYS53D, LYS69I, LYS72I, PHE19D, PHE82I, PRO6I, SER13I, SER14I, SER16I, SER52D, SER55D, SER65I, THR11I, THR18D, THR23D, THR25D, THR31D, THR4I, THR67D, THR67I, TRP10I, TYR50D, TYR57D, TYR60D, VAL3I, VAL68I, VAL70I
• D-J: ASN7J, ASP20D, ASP21D, ASP8J, ASP9J, GLN24D, GLY22D, PHE19D, PRO6J, THR23D, THR25D, THR4J, VAL3J, VAL5J
• D-O: ALA38D, ALA76O, ALA77O, ASN81O, ASP35D, ASP73O, GLN27D, GLN80O, GLY28D, ILE78O, LEU30D, LEU34D, PHE82O, THR31D
• E-J: ALA33E, ALA63E, ALA63J, ALA76J, ARG61J, ASN62J, ASN66J, ASN7J, ASP21E, ASP35E, ASP73J, ASP75J, ASP8J, ASP9J, GLN24E, GLN27E, GLN64J, GLU17E, GLU29E, GLU49E, GLU56E, GLY22E, GLY28E, ILE71J, ILE78J, ILE79J, LEU12J, LEU15E, LEU26E, LEU30E, LEU32E, LEU34E, LEU54E, LEU59E, LYS36E, LYS53E, LYS69J, LYS72J, PHE19E, PRO6J, SER13J, SER14J, SER16J, SER52E, SER55E, SER65J, THR11J, THR18E, THR23E, THR25E, THR31E, THR4J, THR67J, TRP10J, TYR50E, TYR57E, TYR60E, VAL3J, VAL68J
• E-K: ASN7K, ASP20E, ASP21E, ASP8K, ASP9K, GLN24E, GLY22E, PHE19E, PRO6K, THR23E, THR25E, THR4K, VAL3K, VAL5K
• E-P: ALA38E, ALA77P, ASN81P, ASP35E, ASP73P, GLN27E, GLN80P, GLY28E, ILE78P, LEU30E, LEU34E, PHE82P, THR31E
• F-K: ALA33F, ALA63F, ALA63K, ALA76K, ARG61K, ASN62K, ASN66K, ASN7K, ASP21F, ASP35F, ASP73K, ASP75K, ASP9K, GLN24F, GLN27F, GLN64K, GLU17F, GLU29F, GLU49F, GLU56F, GLY22F, GLY28F, ILE71K, ILE78K, ILE79K, LEU12K, LEU15F, LEU26F, LEU30F, LEU32F, LEU34F, LEU54F, LEU59F, LYS36F, LYS53F, LYS69K, LYS72K, PHE19F, PRO6K, SER13K, SER14K, SER16K, SER52F, SER55F, SER65K, THR11K, THR18F, THR23F, THR25F, THR31F, THR4K, THR67K, TRP10K, TYR57F, TYR60F, VAL3K, VAL68K, VAL70K
• F-L: ASN7L, ASP20F, ASP21F, ASP8L, ASP9L, GLN24F, GLY22F, PHE19F, PRO6L, THR23F, THR4L, VAL3L, VAL5L
• F-Q: ALA38F, ALA77Q, ASN81Q, ASP35F, GLN27F, GLN80Q, GLY28F, ILE78Q, LEU30F, LEU32F, LEU34F, PHE82Q, THR31F
• G-L: ALA33G, ALA63G, ALA63L, ALA76L, ARG61L, ASN62L, ASN66L, ASN7L, ASP21G, ASP35G, ASP73L, ASP75L, ASP9L, GLN24G, GLN27G, GLN64L, GLU17G, GLU29G, GLU49G, GLU56G, GLY22G, GLY28G, ILE71L, ILE78L, ILE79L, LEU12L, LEU15G, LEU26G, LEU30G, LEU32G, LEU34G, LEU59G, LYS36G, LYS53G, LYS69L, LYS72L, PHE19G, PHE82L, PRO6L, SER13L, SER14L, SER16L, SER52G, SER55G, SER65L, THR11L, THR18G, THR23G, THR25G, THR31G, THR4L, THR67G, THR67L, TRP10L, TYR50G, TYR57G, TYR60G, VAL3L, VAL68L, VAL70L
• G-M: ASN7M, ASP20G, ASP21G, ASP8M, ASP9M, GLN24G, GLY22G, PHE19G, PRO6M, THR23G, THR25G, THR4M, VAL3M, VAL5M
• G-R: ALA38G, ALA76R, ALA77R, ASN81R, ASP35G, ASP73R, GLN27G, GLN80R, GLY28G, ILE78R, LEU30G, LEU32G, LEU34G, PHE82R, THR31G
• H-M: ALA33H, ALA63H, ALA63M, ALA76M, ARG61M, ASN62M, ASN66M, ASN7M, ASP21H, ASP35H, ASP73M, ASP75M, ASP8M, ASP9M, GLN24H, GLN27H, GLN64M, GLU17H, GLU29H, GLU49H, GLU56H, GLY22H, GLY28H, ILE71M, ILE79M, LEU12M, LEU15H, LEU26H, LEU30H, LEU32H, LEU34H, LEU54H, LEU59H, LYS36H, LYS53H, LYS69M, LYS72M, PHE19H, PHE82M, PRO6M, SER13M, SER14M, SER16M, SER52H, SER55H, SER65M, THR11M, THR18H, THR23H, THR25H, THR31H, THR4M, THR67H, THR67M, TRP10M, TYR50H, TYR57H, TYR60H, VAL3M, VAL68M
• H-N: ASN7N, ASP20H, ASP21H, ASP8N, ASP9N, GLN24H, GLY22H, PHE19H, PRO6N, THR23H, THR25H, THR4N, VAL3N, VAL5N
• H-S: ALA38H, ALA76S, ALA77S, ASN81S, ASP35H, ASP73S, GLN27H, GLN80S, GLY28H, ILE78S, LEU30H, LEU34H, PHE82S, THR31H
• I-N: ALA33I, ALA63I, ALA63N, ALA76N, ARG61N, ASN62N, ASN66N, ASN7N, ASP21I, ASP35I, ASP73N, ASP75N, ASP9N, GLN24I, GLN27I, GLN64N, GLU17I, GLU29I, GLU49I, GLU56I, GLY22I, GLY28I, ILE71N, ILE78N, ILE79N, LEU12N, LEU15I, LEU26I, LEU30I, LEU32I, LEU34I, LEU54I, LEU59I, LYS36I, LYS53I, LYS69N, LYS72N, PHE19I, PRO6N, SER13N, SER16N, SER52I, SER55I, SER65N, THR11N, THR18I, THR23I, THR25I, THR31I, THR4N, THR67N, TRP10N, TYR50I, TYR57I, TYR60I, VAL3N, VAL68N
• I-O: ASN7O, ASP20I, ASP21I, ASP8O, ASP9O, GLN24I, GLY22I, PHE19I, PRO6O, THR23I, THR4O, VAL3O, VAL5O
• I-T: ALA38I, ALA77T, ASN81T, ASP35I, ASP73T, GLN27I, GLN80T, GLY28I, ILE78T, LEU30I, LEU32I, LEU34I, PHE82T, THR31I
• J-O: ALA33J, ALA63J, ALA63O, ALA76O, ARG61O, ASN62O, ASN66O, ASN7O, ASP21J, ASP35J, ASP73O, ASP75O, ASP9O, GLN24J, GLN27J, GLN64O, GLU17J, GLU29J, GLU49J, GLU56J, GLY22J, GLY28J, ILE71O, ILE78O, ILE79O, LEU12O, LEU15J, LEU26J, LEU30J, LEU32J, LEU34J, LEU59J, LYS36J, LYS53J, LYS69O, LYS72O, PHE19J, PHE82O, PRO6O, SER13O, SER14O, SER16O, SER52J, SER55J, SER65O, THR11O, THR18J, THR23J, THR25J, THR31J, THR4O, THR67J, THR67O, TRP10O, TYR50J, TYR57J, TYR60J, VAL3O, VAL68O, VAL70O
• J-P: ASN7P, ASP20J, ASP21J, ASP8P, ASP9P, GLN24J, GLY22J, PHE19J, PRO6P, THR23J, THR4P, VAL3P, VAL5P
• J-U: ALA38J, ALA77U, ASN81U, ASP35J, GLN27J, GLN80U, ILE78U, LEU30J, LEU32J, LEU34J, PHE82U, THR31J
• K-P: ALA33K, ALA63K, ALA63P, ALA76P, ARG61P, ASN62P, ASN66P, ASN7P, ASP21K, ASP35K, ASP73P, ASP75P, ASP9P, GLN24K, GLN27K, GLN64P, GLU17K, GLU29K, GLU49K, GLU56K, GLY22K, GLY28K, ILE71P, ILE79P, LEU12P, LEU15K, LEU26K, LEU30K, LEU32K, LEU34K, LEU59K, LYS36K, LYS53K, LYS69P, LYS72P, PHE19K, PHE82P, PRO6P, SER13P, SER14P, SER16P, SER52K, SER55K, SER65P, THR11P, THR18K, THR23K, THR25K, THR31K, THR4P, THR67K, THR67P, TRP10P, TYR50K, TYR57K, TYR60K, VAL3P, VAL68P, VAL70P
• K-Q: ASN7Q, ASP20K, ASP21K, ASP8Q, ASP9Q, GLN24K, GLY22K, PHE19K, PRO6Q, THR23K, THR25K, THR4Q, VAL3Q, VAL5Q
• K-V: ALA38K, ALA76V, ALA77V, ASN81V, ASP35K, ASP73V, GLN27K, GLN80V, GLY28K, ILE78V, LEU30K, LEU34K, PHE82V, THR31K
• L-Q: ALA33L, ALA63L, ALA63Q, ALA76Q, ARG61Q, ASN62Q, ASN66Q, ASN7Q, ASP21L, ASP35L, ASP73Q, ASP75Q, ASP8Q, ASP9Q, GLN24L, GLN27L, GLN64Q, GLU17L, GLU29L, GLU49L, GLU56L, GLY22L, GLY28L, ILE71Q, ILE78Q, ILE79Q, LEU12Q, LEU15L, LEU26L, LEU30L, LEU32L, LEU34L, LEU54L, LEU59L, LYS36L, LYS53L, LYS69Q, LYS72Q, PHE19L, PRO6Q, SER13Q, SER14Q, SER16Q, SER52L, SER55L, SER65Q, THR11Q, THR18L, THR23L, THR25L, THR31L, THR4Q, THR67Q, TRP10Q, TYR50L, TYR57L, TYR60L, VAL3Q, VAL68Q
• L-R: ASN7R, ASP20L, ASP21L, ASP8R, ASP9R, GLN24L, GLY22L, PHE19L, PRO6R, THR23L, THR25L, THR4R, VAL3R, VAL5R
• L-W: ALA38L, ALA77W, ASN81W, ASP35L, ASP73W, GLN27L, GLN80W, GLY28L, ILE78W, LEU30L, LEU34L, PHE82W, THR31L
• M-R: ALA33M, ALA63M, ALA63R, ALA76R, ARG61R, ASN62R, ASN66R, ASN7R, ASP21M, ASP35M, ASP73R, ASP75R, ASP9R, GLN24M, GLN27M, GLN64R, GLU17M, GLU29M, GLU49M, GLU56M, GLY22M, GLY28M, ILE71R, ILE78R, ILE79R, LEU12R, LEU15M, LEU26M, LEU30M, LEU32M, LEU34M, LEU54M, LEU59M, LYS36M, LYS53M, LYS69R, LYS72R, PHE19M, PRO6R, SER13R, SER14R, SER16R, SER52M, SER55M, SER65R, THR11R, THR18M, THR23M, THR25M, THR31M, THR4R, THR67R, TRP10R, TYR57M, TYR60M, VAL3R, VAL68R, VAL70R
• M-S: ASN7S, ASP20M, ASP21M, ASP8S, ASP9S, GLN24M, GLY22M, PHE19M, PRO6S, THR23M, THR4S, VAL3S, VAL5S
• M-X: ALA38M, ALA77X, ASN81X, ASP35M, GLN27M, GLN80X, GLY28M, ILE78X, LEU30M, LEU32M, LEU34M, PHE82X, THR31M
• N-S: ALA33N, ALA63N, ALA63S, ALA76S, ARG61S, ASN62S, ASN66S, ASN7S, ASP21N, ASP35N, ASP73S, ASP75S, ASP9S, GLN24N, GLN27N, GLN64S, GLU17N, GLU29N, GLU49N, GLU56N, GLY22N, GLY28N, ILE71S, ILE78S, ILE79S, LEU12S, LEU15N, LEU26N, LEU30N, LEU32N, LEU34N, LEU59N, LYS36N, LYS53N, LYS69S, LYS72S, PHE19N, PHE82S, PRO6S, SER13S, SER14S, SER16S, SER52N, SER55N, SER65S, THR11S, THR18N, THR23N, THR25N, THR31N, THR4S, THR67N, THR67S, TRP10S, TYR50N, TYR57N, TYR60N, VAL3S, VAL68S, VAL70S
• N-T: ASN7T, ASP20N, ASP21N, ASP8T, ASP9T, GLN24N, GLY22N, PHE19N, PRO6T, THR23N, THR25N, THR4T, VAL3T, VAL5T
• N-Y: ALA38N, ALA76Y, ALA77Y, ASN81Y, ASP35N, ASP73Y, GLN27N, GLN80Y, GLY28N, ILE78Y, LEU30N, LEU32N, LEU34N, PHE82Y, THR31N
• O-T: ALA33O, ALA63O, ALA63T, ALA76T, ARG61T, ASN62T, ASN66T, ASN7T, ASP21O, ASP35O, ASP73T, ASP75T, ASP8T, ASP9T, GLN24O, GLN27O, GLN64T, GLU17O, GLU29O, GLU49O, GLU56O, GLY22O, GLY28O, ILE71T, ILE79T, LEU12T, LEU15O, LEU26O, LEU30O, LEU32O, LEU34O, LEU54O, LEU59O, LYS36O, LYS53O, LYS69T, LYS72T, PHE19O, PHE82T, PRO6T, SER13T, SER14T, SER16T, SER52O, SER55O, SER65T, THR11T, THR18O, THR23O, THR25O, THR31O, THR4T, THR67O, THR67T, TRP10T, TYR50O, TYR57O, TYR60O, VAL3T, VAL68T
• O-U: ASN7U, ASP20O, ASP21O, ASP8U, ASP9U, GLN24O, GLY22O, PHE19O, PRO6U, THR23O, THR25O, THR4U, VAL3U, VAL5U
• O-Z: ALA38O, ALA76Z, ALA77Z, ASN81Z, ASP35O, ASP73Z, GLN27O, GLN80Z, GLY28O, ILE78Z, LEU30O, LEU34O, PHE82Z, THR31O
• P-U: ALA33P, ALA63P, ALA63U, ALA76U, ARG61U, ASN62U, ASN66U, ASN7U, ASP21P, ASP35P, ASP73U, ASP75U, ASP9U, GLN24P, GLN27P, GLN64U, GLU17P, GLU29P, GLU49P, GLU56P, GLY22P, GLY28P, ILE71U, ILE78U, ILE79U, LEU12U, LEU15P, LEU26P, LEU30P, LEU32P, LEU34P, LEU54P, LEU59P, LYS36P, LYS53P, LYS69U, LYS72U, PHE19P, PRO6U, SER13U, SER16U, SER52P, SER55P, SER65U, THR11U, THR18P, THR23P, THR25P, THR31P, THR4U, THR67U, TRP10U, TYR50P, TYR57P, TYR60P, VAL3U, VAL68U
• P-V: ASN7V, ASP20P, ASP21P, ASP8V, ASP9V, GLN24P, GLY22P, PHE19P, PRO6V, THR23P, THR4V, VAL3V, VAL5V
• Q-V: ALA33Q, ALA63Q, ALA63V, ALA76V, ARG61V, ASN62V, ASN66V, ASN7V, ASP21Q, ASP35Q, ASP73V, ASP75V, ASP9V, GLN24Q, GLN27Q, GLN64V, GLU17Q, GLU29Q, GLU49Q, GLU56Q, GLY22Q, GLY28Q, ILE71V, ILE78V, ILE79V, LEU12V, LEU15Q, LEU26Q, LEU30Q, LEU32Q, LEU34Q, LEU59Q, LYS36Q, LYS53Q, LYS69V, LYS72V, PHE19Q, PHE82V, PRO6V, SER13V, SER14V, SER16V, SER52Q, SER55Q, SER65V, THR11V, THR18Q, THR23Q, THR25Q, THR31Q, THR4V, THR67Q, THR67V, TRP10V, TYR50Q, TYR57Q, TYR60Q, VAL3V, VAL68V, VAL70V
• Q-W: ASN7W, ASP20Q, ASP21Q, ASP8W, ASP9W, GLN24Q, GLY22Q, PHE19Q, PRO6W, THR23Q, THR4W, VAL3W, VAL5W
• R-W: ALA33R, ALA63R, ALA63W, ALA76W, ARG61W, ASN62W, ASN66W, ASN7W, ASP21R, ASP35R, ASP73W, ASP75W, ASP9W, GLN24R, GLN27R, GLN64W, GLU17R, GLU29R, GLU49R, GLU56R, GLY22R, GLY28R, ILE71W, ILE79W, LEU12W, LEU15R, LEU26R, LEU30R, LEU32R, LEU34R, LEU59R, LYS36R, LYS53R, LYS69W, LYS72W, PHE19R, PHE82W, PRO6W, SER13W, SER14W, SER16W, SER52R, SER55R, SER65W, THR11W, THR18R, THR23R, THR25R, THR31R, THR4W, THR67R, THR67W, TRP10W, TYR50R, TYR57R, TYR60R, VAL3W, VAL68W, VAL70W
• R-X: ASN7X, ASP20R, ASP21R, ASP8X, ASP9X, GLN24R, GLY22R, PHE19R, PRO6X, THR23R, THR25R, THR4X, VAL3X, VAL5X
• S-X: ALA33S, ALA63S, ALA63X, ALA76X, ARG61X, ASN62X, ASN66X, ASN7X, ASP21S, ASP35S, ASP73X, ASP75X, ASP8X, ASP9X, GLN24S, GLN27S, GLN64X, GLU17S, GLU29S, GLU49S, GLU56S, GLY22S, GLY28S, ILE71X, ILE78X, ILE79X, LEU12X, LEU15S, LEU26S, LEU30S, LEU32S, LEU34S, LEU54S, LEU59S, LYS36S, LYS53S, LYS69X, LYS72X, PHE19S, PRO6X, SER13X, SER14X, SER16X, SER52S, SER55S, SER65X, THR11X, THR18S, THR23S, THR25S, THR31S, THR4X, THR67X, TRP10X, TYR50S, TYR57S, TYR60S, VAL3X, VAL68X
• S-Y: ASN7Y, ASP20S, ASP21S, ASP8Y, ASP9Y, GLN24S, GLY22S, PHE19S, PRO6Y, THR23S, THR25S, THR4Y, VAL3Y, VAL5Y
• T-Y: ALA33T, ALA63T, ALA63Y, ALA76Y, ARG61Y, ASN62Y, ASN66Y, ASN7Y, ASP21T, ASP35T, ASP73Y, ASP75Y, ASP9Y, GLN24T, GLN27T, GLN64Y, GLU17T, GLU29T, GLU49T, GLU56T, GLY22T, GLY28T, ILE71Y, ILE78Y, ILE79Y, LEU12Y, LEU15T, LEU26T, LEU30T, LEU32T, LEU34T, LEU54T, LEU59T, LYS36T, LYS53T, LYS69Y, LYS72Y, PHE19T, PRO6Y, SER13Y, SER14Y, SER16Y, SER52T, SER55T, SER65Y, THR11Y, THR18T, THR23T, THR25T, THR31T, THR4Y, THR67Y, TRP10Y, TYR57T, TYR60T, VAL3Y, VAL68Y, VAL70Y
• T-Z: ASN7Z, ASP20T, ASP21T, ASP8Z, ASP9Z, GLN24T, GLY22T, PHE19T, PRO6Z, THR23T, THR4Z, VAL3Z, VAL5Z
• U-Z: ALA33U, ALA63U, ALA63Z, ALA76Z, ARG61Z, ASN62Z, ASN66Z, ASN7Z, ASP21U, ASP35U, ASP73Z, ASP75Z, ASP9Z, GLN24U, GLN27U, GLN64Z, GLU17U, GLU29U, GLU49U, GLU56U, GLY22U, GLY28U, ILE71Z, ILE78Z, ILE79Z, LEU12Z, LEU15U, LEU26U, LEU30U, LEU32U, LEU34U, LEU59U, LYS36U, LYS53U, LYS69Z, LYS72Z, PHE19U, PHE82Z, PRO6Z, SER13Z, SER14Z, SER16Z, SER52U, SER55U, SER65Z, THR11Z, THR18U, THR23U, THR25U, THR31U, THR4Z, THR67U, THR67Z, TRP10Z, TYR50U, TYR57U, TYR60U, VAL3Z, VAL68Z, VAL70Z