2V6B

crystal structure of lactate dehydrogenase from deinococcus radiodurans (apo form)

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 103
  • Norm. En. per Res.: -2.6116
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-41.5118	-5.5938	-269.666	-316.7716	132	18	13	11458	1	31	33
A-C	-6.5245	42.5405	-94.7455	-58.7295	60	10	0	4660	0	24	36
A-D	-34.1837	-30.1891	-197.127	-261.4999	102	17	11	8413	1	21	33
B-C	-27.6661	-47.4912	-193.84	-268.9972	103	27	11	8281	4	22	33
B-D	-23.1447	30.7801	-107.287	-99.6516	62	14	0	5069	0	23	37
C-D	-23.8358	-1.582	-274.436	-299.8537	135	15	13	11515	0	29	32

Interface residues

• A-B: ALA170A, ALA170B, ALA252A, ALA252B, ALA253A, ALA253B, ALA255A, ALA255B, ALA36A, ALA36B, ALA37A, ALA37B, ALA39A, ALA39B, ALA61A, ALA61B, ALA63A, ALA63B, ALA67A, ALA67B, ALA69A, ALA69B, ALA70A, ALA70B, ARG171A, ARG171B, ARG173A, ARG173B, ARG256A, ARG256B, ARG265A, ARG43A, ARG43B, ARG58A, ARG58B, ARG77A, ARG77B, ASN234A, ASP168A, ASP168B, ASP183A, ASP183B, ASP65A, ASP65B, GLN178A, GLN178B, GLN60A, GLN60B, GLU259A, GLU62A, GLU62B, GLU64A, GLU64B, GLY184A, GLY184B, GLY231A, GLY231B, GLY249A, GLY249B, GLY251A, GLY251B, GLY30A, GLY30B, GLY33A, GLY33B, GLY44A, GLY44B, GLY75A, GLY75B, HIS174A, HIS174B, HIS68A, HIS68B, HIS74A, HIS74B, ILE250A, ILE250B, ILE66A, ILE66B, LEU167A, LEU167B, LEU175A, LEU175B, LEU40A, LEU40B, LEU42A, LEU42B, LEU51A, LEU51B, LYS227A, MET176A, PHE172A, PHE172B, PHE31A, PHE31B, PHE38A, PHE38B, PRO71A, PRO71B, SER169B, SER34A, SER34B, SER45A, SER45B, SER73A, SER73B, THR185A, THR185B, THR232A, THR232B, THR246A, THR246B, THR29A, THR29B, THR35A, THR35B, THR76A, THR76B, TRP79A, TRP79B, TYR247A, TYR247B, TYR248A, TYR248B, VAL32A, VAL32B, VAL41A, VAL41B, VAL72A, VAL72B, VAL78A, VAL78B
• A-C: ALA260A, ALA260C, ALA70A, ALA70C, ARG256A, ARG256C, ARG263A, ARG263C, ARG265A, ARG265C, ARG266A, ARG266C, ARG295A, ARG295C, ARG43A, ARG43C, ARG77A, ARG77C, ASP264A, ASP264C, CYS46A, CYS46C, GLN92A, GLN92C, GLU259A, GLU259C, GLU48A, GLU48C, GLY44A, GLY44C, GLY75A, GLY75C, HIS74A, HIS74C, LEU262A, LEU262C, LEU40A, LEU40C, LEU42C, LYS23A, LYS23C, MET22A, MET22C, PRO71A, PRO71C, SER45A, SER45C, SER47A, SER47C, SER73A, SER73C, THR185A, THR185C, THR76A, THR76C, VAL261A, VAL41A, VAL41C, VAL72A, VAL72C
• A-D: ALA177A, ALA177D, ALA180A, ALA180D, ALA187A, ALA187D, ALA206A, ALA206D, ALA209A, ALA209D, ALA215A, ALA215D, ALA260A, ALA260D, ALA267A, ALA267D, ALA70A, ALA70D, ARG173A, ARG173D, ARG265A, ARG265D, ARG266A, ARG266D, ARG291A, ARG291D, ASP183A, ASP183D, ASP211A, ASP211D, ASP264A, ASP264D, GLN178A, GLN178D, GLN214A, GLN216A, GLN216D, GLY181A, GLY181D, GLY184A, GLY184D, GLY189A, GLY189D, GLY209A, GLY209D, HIS186A, HIS186D, HIS188A, HIS188D, HIS304A, HIS304D, HIS74A, HIS74D, LEU218A, LEU218D, LEU269A, LEU269D, LEU299A, LEU299D, LEU303A, LEU303D, LEU42A, LYS306A, LYS306D, MET207A, MET207D, MET209A, MET209D, PHE212A, PHE212D, PRO209A, PRO209D, PRO290A, PRO290D, PRO305A, PRO305D, PRO71A, PRO71D, SER205A, SER205D, SER301A, SER301D, SER73A, SER73D, THR185A, THR185D, THR302A, THR302D, TYR190A, TYR190D, VAL182A, VAL182D, VAL208A, VAL208D, VAL268A, VAL268D, VAL292A, VAL292D, VAL293A, VAL293D, VAL72A, VAL72D
• B-C: ALA177B, ALA177C, ALA180B, ALA180C, ALA187B, ALA187C, ALA206B, ALA206C, ALA209B, ALA209C, ALA215B, ALA215C, ALA260B, ALA260C, ALA267B, ALA267C, ALA70B, ALA70C, ARG173B, ARG173C, ARG263B, ARG263C, ARG265B, ARG265C, ARG266B, ARG266C, ARG291B, ARG291C, ASP183B, ASP183C, ASP264B, ASP264C, GLN178B, GLN178C, GLN216B, GLN216C, GLY181B, GLY181C, GLY184B, GLY184C, GLY189B, GLY189C, GLY209B, GLY209C, HIS174B, HIS174C, HIS186B, HIS186C, HIS188B, HIS188C, HIS304B, HIS304C, HIS74B, HIS74C, LEU218C, LEU269B, LEU269C, LEU299B, LEU299C, LEU303B, LEU303C, LEU42B, LYS306B, LYS306C, MET207B, MET207C, MET209B, MET209C, PHE212B, PHE212C, PRO209B, PRO209C, PRO290B, PRO290C, PRO305B, PRO305C, PRO71B, PRO71C, SER204C, SER205B, SER205C, SER301B, SER301C, SER73B, SER73C, THR185B, THR185C, THR302B, THR302C, TYR190B, TYR190C, VAL182B, VAL182C, VAL208B, VAL208C, VAL268B, VAL268C, VAL292B, VAL292C, VAL293B, VAL293C, VAL72B, VAL72C
• B-D: ALA260B, ALA260D, ALA67D, ALA70B, ALA70D, ARG256B, ARG256D, ARG263B, ARG263D, ARG265B, ARG265D, ARG266B, ARG266D, ARG295B, ARG295D, ARG43B, ARG43D, ARG77B, ARG77D, ASP264B, ASP264D, CYS46B, CYS46D, GLN92B, GLN92D, GLU259B, GLU259D, GLU48B, GLU48D, GLY294D, GLY44B, GLY44D, GLY75B, GLY75D, HIS74B, HIS74D, LEU262B, LEU262D, LEU299D, LEU40B, LEU40D, LYS23B, LYS23D, MET22B, MET22D, PRO71B, PRO71D, SER45B, SER45D, SER47B, SER47D, SER73B, SER73D, THR185B, THR185D, THR76B, THR76D, VAL41B, VAL41D, VAL72B, VAL72D, VAL78D
• C-D: ALA170C, ALA170D, ALA252C, ALA252D, ALA253C, ALA253D, ALA255C, ALA255D, ALA36C, ALA36D, ALA37C, ALA37D, ALA39C, ALA39D, ALA61C, ALA61D, ALA63C, ALA63D, ALA67C, ALA67D, ALA69C, ALA69D, ALA70C, ALA70D, ARG171C, ARG171D, ARG173C, ARG173D, ARG256C, ARG256D, ARG265C, ARG265D, ARG43C, ARG43D, ARG58C, ARG58D, ARG77C, ARG77D, ASN234C, ASP168C, ASP168D, ASP183C, ASP183D, ASP65C, ASP65D, GLN178C, GLN178D, GLN60C, GLN60D, GLU230C, GLU259C, GLU259D, GLU62C, GLU62D, GLU64C, GLU64D, GLY184C, GLY184D, GLY231C, GLY231D, GLY249C, GLY249D, GLY251C, GLY251D, GLY30C, GLY30D, GLY33C, GLY33D, GLY44C, GLY44D, GLY75C, GLY75D, HIS174C, HIS174D, HIS186C, HIS68C, HIS68D, HIS74C, HIS74D, HIS80C, ILE250C, ILE250D, ILE66C, ILE66D, LEU167C, LEU167D, LEU175C, LEU175D, LEU40C, LEU40D, LEU42C, LEU42D, LEU51C, LEU51D, LYS227C, LYS227D, PHE172C, PHE172D, PHE31C, PHE31D, PHE38C, PHE38D, PRO71C, PRO71D, SER34C, SER34D, SER45C, SER73C, SER73D, THR185C, THR185D, THR232C, THR232D, THR246C, THR246D, THR29C, THR29D, THR35C, THR35D, THR76C, THR76D, TRP79C, TRP79D, TYR247C, TYR247D, TYR248C, TYR248D, VAL32C, VAL32D, VAL41C, VAL41D, VAL72C, VAL72D, VAL78C, VAL78D