2V4J

the crystal structure of desulfovibrio vulgaris dissimilatory sulfite reductase bound to dsrc provides novel insights into the mechanism of sulfate respiration

• Total interactions analyzed: 15
• Total true interactions: 12
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 214
  • Norm. En. per Res.: -5.8205
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-356.9256	-169.953	-2026.17	-2553.0487	504	85	22	72737	20	127	152
A-C	-37.1101	-37.1585	-223.028	-297.2966	104	14	3	9125	1	33	20
A-D	-54.3866	-136.3209	-177.54	-368.2475	84	4	0	6627	8	49	46
A-E	-188.1661	-146.6682	-865.848	-1200.6823	213	32	8	34033	10	96	86
A-F	0.0	0.0	-0.3545	-0.3545	6	0	0	40	0	7	2
B-C	-26.3524	11.1481	-108.102	-123.3063	71	7	2	4706	0	22	16
B-D	-170.9514	-177.0609	-897.583	-1245.5953	214	37	9	34368	13	96	87
B-E	-32.6122	-41.5722	-155.812	-229.9964	62	7	0	5183	2	2	8
C-D	0.0	0.0	-0.4299	-0.4299	7	0	0	51	0	7	2
D-E	-392.5706	-166.0011	-2030.85	-2589.4217	506	91	25	73186	19	128	153
D-F	-32.6108	-36.523	-235.647	-304.7808	107	18	3	9558	1	34	22
E-F	-11.5453	8.0212	-105.536	-109.0601	75	5	1	4661	0	23	16

Interface residues

• A-B: ALA103A, ALA112A, ALA137B, ALA155B, ALA158B, ALA15B, ALA164B, ALA180B, ALA186A, ALA192A, ALA193A, ALA195B, ALA227A, ALA227B, ALA229B, ALA230A, ALA234B, ALA263A, ALA265A, ALA270B, ALA278A, ALA28A, ALA29A, ALA2B, ALA316A, ALA329B, ALA331A, ALA331B, ALA333A, ALA339A, ALA35B, ALA56B, ALA69B, ALA70B, ALA85B, ARG101A, ARG116A, ARG125A, ARG177B, ARG17B, ARG182A, ARG183B, ARG207A, ARG231A, ARG24B, ARG269A, ARG283A, ARG292B, ARG305A, ARG312B, ARG315A, ARG31A, ARG323A, ARG336B, ARG343B, ARG366B, ARG376A, ARG378A, ARG66B, ARG71B, ARG79B, ARG83A, ARG94B, ARG98B, ASN100B, ASN131A, ASN141B, ASN159A, ASN161A, ASN16B, ASN191B, ASN223A, ASN262A, ASN263B, ASN282A, ASN291B, ASN308B, ASN311A, ASN330B, ASN375A, ASN37B, ASN410A, ASN99B, ASN9B, ASP10A, ASP113A, ASP120A, ASP123A, ASP124B, ASP138A, ASP157B, ASP163A, ASP167B, ASP189A, ASP203A, ASP20B, ASP219A, ASP23A, ASP270A, ASP275A, ASP275B, ASP279B, ASP27B, ASP337A, ASP39A, ASP59A, ASP83B, ASP86A, ASP86B, CYS119A, CYS151B, CYS177A, CYS183A, CYS188B, CYS189B, CYS193B, CYS194A, CYS198B, CYS221A, CYS222B, CYS225A, CYS231B, CYS261B, CYS264B, CYS268B, CYS284A, CYS306A, CYS309A, CYS82B, CYS89B, GLN104A, GLN117A, GLN11A, GLN146B, GLN148A, GLN174B, GLN191A, GLN202A, GLN26A, GLN340A, GLN41A, GLU102B, GLU13A, GLU150A, GLU151A, GLU155A, GLU168B, GLU171B, GLU175A, GLU184A, GLU196A, GLU204A, GLU223B, GLU277B, GLU279A, GLU27A, GLU28B, GLU309B, GLU325B, GLU335B, GLU339B, GLU353A, GLU381A, GLU406A, GLU45B, GLU48B, GLU55A, GLU57B, GLU60A, GLU62A, GLU80B, GLY107A, GLY125B, GLY126A, GLY126B, GLY128A, GLY133B, GLY134A, GLY134B, GLY136B, GLY137A, GLY138B, GLY143A, GLY147B, GLY15A, GLY160B, GLY165A, GLY179A, GLY194B, GLY224A, GLY22B, GLY238A, GLY262B, GLY264A, GLY268A, GLY272A, GLY276B, GLY278B, GLY287B, GLY338A, GLY342A, GLY37A, GLY39B, GLY61A, GLY68A, GLY68B, GLY69A, GLY72A, GLY75A, GLY7B, GLY82A, GLY90B, GLY91B, HIS133A, HIS144B, HIS150B, HIS152B, HIS158A, HIS197B, HIS206A, HIS207B, HIS266A, HIS308A, HIS318A, HIS44B, HIS54B, HIS64A, HIS67A, HIS77B, HIS92B, HIS96A, HIS98A, ILE121A, ILE132B, ILE139A, ILE142B, ILE152A, ILE165B, ILE18B, ILE190B, ILE21B, ILE229A, ILE237A, ILE24A, ILE273B, ILE276A, ILE293B, ILE310A, ILE324B, ILE335A, ILE34B, ILE46B, ILE4B, ILE75B, ILE78B, ILE81A, ILE84B, LEU115A, LEU118A, LEU124A, LEU128B, LEU129A, LEU12A, LEU141A, LEU142A, LEU149A, LEU156A, LEU160A, LEU164A, LEU178A, LEU178B, LEU186B, LEU205A, LEU221B, LEU226B, LEU271B, LEU317A, LEU328A, LEU336A, LEU344A, LEU38A, LEU42B, LEU47B, LEU50A, LEU51A, LEU52B, LEU54A, LEU56A, LEU72B, LEU93B, LEU9A, LYS108A, LYS122B, LYS129B, LYS12B, LYS163B, LYS180A, LYS213A, LYS215A, LYS217A, LYS245A, LYS25A, LYS25B, LYS260A, LYS273A, LYS287A, LYS288B, LYS297B, LYS300B, LYS332A, LYS333B, LYS36A, LYS374A, LYS384A, LYS405A, LYS61B, LYS66A, LYS87B, LYS8A, MET104B, MET132A, MET14B, MET166B, MET176B, MET192B, MET199A, MET212B, MET259B, MET267B, MET284B, MET295B, MET307A, MET313A, MET341A, MET53B, MET73B, MET81B, PHE103B, PHE123B, PHE130B, PHE153A, PHE154A, PHE170B, PHE173B, PHE185A, PHE20A, PHE218A, PHE259A, PHE26B, PHE274A, PHE298B, PHE29B, PHE30B, PHE355A, PHE365B, PHE38B, PHE3B, PHE74A, PHE95B, PHE97A, PRO105A, PRO10B, PRO131B, PRO13B, PRO147A, PRO154B, PRO161B, PRO16A, PRO174A, PRO179B, PRO181B, PRO18A, PRO222A, PRO232B, PRO23B, PRO261A, PRO269B, PRO272B, PRO285A, PRO296B, PRO310B, PRO311B, PRO314A, PRO31B, PRO334A, PRO35A, PRO368B, PRO47A, PRO49B, PRO7A, SER106A, SER111A, SER127A, SER127B, SER135A, SER140B, SER14A, SER159B, SER175B, SER176A, SER181A, SER185B, SER190A, SER199B, SER19A, SER228A, SER22A, SER230B, SER232A, SER267A, SER274B, SER286A, SER290B, SER294B, SER299B, SER326A, SER328B, SER40B, SER57A, SER5B, SER6B, SER74B, THR130A, THR135B, THR136A, THR144A, THR145B, THR153B, THR156B, THR157A, THR162A, THR173A, THR198A, THR19B, THR233B, THR266B, THR312A, THR317B, THR409A, THR63A, THR64B, THR6A, THR76B, THR96B, THR97B, THR99A, TRP122A, TRP148B, TRP17A, TRP271A, TRP313B, TRP340B, TRP41B, TRP65A, TYR109A, TYR110A, TYR114A, TYR188A, TYR195A, TYR201A, TYR212A, TYR254A, TYR265B, TYR30A, TYR327B, TYR332B, TYR334B, TYR370B, TYR371B, TYR40A, TYR43B, TYR58A, TYR63B, TYR76A, TYR84A, TYR8B, VAL100A, VAL101B, VAL102A, VAL105B, VAL139B, VAL140A, VAL143B, VAL149B, VAL162B, VAL169B, VAL196B, VAL204B, VAL21A, VAL226A, VAL228B, VAL280A, VAL289B, VAL304A, VAL33B, VAL404A, VAL53A, VAL55B, VAL62B, VAL65B, VAL67B, VAL73A, VAL80A, VAL94A
• A-C: ALA209A, ALA63C, ALA95A, ARG101A, ARG172A, ARG207A, ARG376A, ARG378A, ARG385A, ARG67C, ARG83A, ASN170A, ASN375A, ASP14C, ASP16C, ASP203A, ASP367A, ASP86A, CYS104C, CYS85A, CYS93C, GLU150A, GLU15C, GLU204A, GLU35C, GLU371A, GLU372A, GLU377A, GLU37C, GLU3C, GLU79C, GLU82C, GLY103C, GLY166A, GLY168A, GLY17C, GLY373A, GLY38C, GLY68A, GLY69A, GLY72A, GLY75A, GLY77A, GLY78A, GLY79A, GLY82A, GLY87C, GLY89C, GLY91C, HIS206A, HIS67A, HIS96A, HIS98A, ILE39C, ILE62C, ILE68C, ILE70A, ILE81A, LEU149A, LEU77C, LYS100C, LYS213A, LYS215A, LYS34C, LYS374A, LYS66A, LYS71C, LYS76C, LYS78C, LYS90C, LYS94C, MET370A, MET65C, PHE18C, PHE210A, PHE74A, PHE84C, PRO101C, PRO208A, PRO211A, PRO64C, PRO85C, PRO88A, PRO88C, PRO99C, SER167A, SER169A, SER36C, SER70C, SER86C, THR102C, THR146A, TRP368A, TRP369A, TYR212A, TYR76A, TYR81C, TYR84A, VAL105C, VAL66C, VAL71A, VAL73A, VAL80A, VAL80C
• A-D: ALA333A, ALA333D, ALA339A, ALA339D, ARG426A, ARG426D, ARG432A, ARG432D, ARG434A, ARG434D, ARG437A, ARG437D, ASN282A, ASN282D, ASN410A, ASN410D, ASP337A, ASP337D, ASP86A, ASP86D, CYS85A, CYS85D, GLN340A, GLN340D, GLN87A, GLN87D, GLU381A, GLU381D, GLU60A, GLU60D, GLU62A, GLU62D, GLU89A, GLU89D, GLY338A, GLY338D, GLY61A, GLY61D, HIS435A, HIS435D, HIS64A, HIS64D, HIS67A, HIS67D, ILE335A, ILE335D, LEU336A, LEU336D, LEU436A, LEU436D, LEU56A, LEU56D, LYS287A, LYS287D, LYS332A, LYS332D, LYS433A, LYS433D, LYS66A, LYS66D, LYS90A, LYS90D, MET341A, MET341D, PRO334A, PRO334D, PRO411A, PRO411D, PRO88A, PRO88D, SER57A, SER57D, THR409A, THR409D, THR63A, THR63D, TRP65A, TRP65D, TYR412A, TYR412D, TYR431A, TYR431D, TYR84A, TYR84D
• A-E: ALA230A, ALA235E, ALA270E, ALA304E, ALA325A, ALA331A, ALA339A, ALA341E, ALA369E, ALA398A, ARG208E, ARG257E, ARG305A, ARG343E, ARG348E, ARG366E, ARG374E, ARG385A, ARG408A, ARG426A, ARG432A, ARG434A, ARG437A, ASN191E, ASN223A, ASN255E, ASN263E, ASN300A, ASN410A, ASP214E, ASP219A, ASP242A, ASP275E, ASP279E, ASP299A, ASP337A, ASP363E, ASP364E, ASP367E, ASP425A, ASP427A, CYS189E, CYS198E, CYS221A, CYS258E, CYS261E, CYS284A, CYS288A, CYS303A, CYS306A, CYS329A, GLN340A, GLN375E, GLN378E, GLN389A, GLN402A, GLU216E, GLU256E, GLU277E, GLU302A, GLU322A, GLU342E, GLU347E, GLU356E, GLU381A, GLU393A, GLU406A, GLU417A, GLU419A, GLU430A, GLY205E, GLY224A, GLY238A, GLY262E, GLY276E, GLY278E, GLY286E, GLY324A, GLY330A, GLY338A, GLY342A, GLY345E, GLY380A, GLY422A, GLY423A, HIS152E, HIS197E, HIS207E, HIS215E, HIS308A, HIS359E, HIS360E, HIS403A, HIS435A, ILE190E, ILE206E, ILE213E, ILE229A, ILE237A, ILE273E, ILE283E, ILE306E, ILE327A, ILE344E, ILE362E, ILE397A, ILE413A, ILE428A, LEU221E, LEU271E, LEU328A, LEU344A, LEU345A, LEU352E, LEU355E, LEU361E, LEU379A, LEU386A, LEU391A, LEU392A, LYS209E, LYS241A, LYS254E, LYS287A, LYS297E, LYS300E, LYS301A, LYS332A, LYS380E, LYS384A, LYS390A, LYS405A, LYS416A, MET192E, MET212E, MET259E, MET284E, MET307A, MET341A, MET383A, PHE298E, PHE348A, PHE349E, PHE350E, PHE357E, PHE365E, PHE379E, PHE381E, PHE388A, PHE414A, PHE415A, PRO210E, PRO211E, PRO222A, PRO232E, PRO269E, PRO272E, PRO285A, PRO307E, PRO347A, PRO368E, PRO399A, PRO401A, PRO407A, PRO411A, PRO421A, SER228A, SER235A, SER274E, SER286A, SER299E, SER326A, SER343A, SER351E, SER358E, SER376E, SER387A, THR153E, THR233E, THR239A, THR372E, THR377E, THR382A, THR409A, THR429A, TRP217E, TRP240A, TRP346E, TRP373E, TRP424A, TYR260E, TYR265E, TYR305E, TYR332E, TYR370E, TYR371E, TYR412A, TYR431A, VAL196E, VAL204E, VAL236A, VAL281E, VAL282E, VAL285E, VAL301E, VAL302E, VAL303E, VAL304A, VAL346A, VAL349A, VAL400A, VAL404A, VAL420A
• A-F: ARG437A, ASP14F, GLU15F, LEU20F, LEU436A, LYS100F
• B-C: ALA227B, ALA229B, ALA270B, ALA63C, ARG17B, ARG21C, ASN191B, ASN263B, ASN60C, ASP14C, ASP219B, ASP23C, ASP24C, CYS104C, CYS151B, CYS193B, CYS222B, CYS264B, CYS268B, CYS93C, GLN220B, GLU11B, GLU12C, GLU216B, GLU223B, GLU35C, GLU37C, GLU82C, GLY103C, GLY38C, GLY61C, GLY97C, HIS152B, ILE224B, ILE39C, ILE62C, LEU19C, LEU20C, LEU221B, LEU226B, LEU98C, LYS100C, LYS246B, MET14B, MET267B, MET65C, PHE18C, PHE22C, PHE84C, PRO101C, PRO10B, PRO13B, PRO225B, PRO269B, PRO64C, PRO85C, PRO99C, SER40C, SER86C, THR102C, THR153B, THR218B, THR266B, TRP217B, TYR265B, TYR56C, TYR57C, TYR81C, TYR8B, VAL105C, VAL228B
• B-D: ALA230D, ALA235B, ALA270B, ALA304B, ALA325D, ALA331D, ALA339D, ALA341B, ALA369B, ALA398D, ARG208B, ARG257B, ARG305D, ARG343B, ARG348B, ARG366B, ARG374B, ARG385D, ARG408D, ARG426D, ARG432D, ARG434D, ARG437D, ASN191B, ASN223D, ASN255B, ASN263B, ASN300D, ASN410D, ASP214B, ASP219D, ASP242D, ASP275B, ASP279B, ASP299D, ASP337D, ASP363B, ASP364B, ASP367B, ASP425D, ASP427D, CYS189B, CYS198B, CYS221D, CYS258B, CYS261B, CYS288D, CYS303D, CYS306D, CYS329D, GLN340D, GLN375B, GLN378B, GLN389D, GLN402D, GLU216B, GLU256B, GLU277B, GLU302D, GLU322D, GLU342B, GLU347B, GLU356B, GLU381D, GLU393D, GLU406D, GLU417D, GLU418D, GLU419D, GLU430D, GLY205B, GLY224D, GLY238D, GLY262B, GLY276B, GLY278B, GLY286B, GLY324D, GLY330D, GLY338D, GLY342D, GLY345B, GLY380D, GLY422D, GLY423D, HIS152B, HIS197B, HIS207B, HIS215B, HIS308D, HIS359B, HIS360B, HIS403D, HIS435D, ILE190B, ILE206B, ILE213B, ILE229D, ILE237D, ILE273B, ILE283B, ILE306B, ILE327D, ILE344B, ILE362B, ILE397D, ILE413D, ILE428D, LEU221B, LEU271B, LEU328D, LEU344D, LEU345D, LEU352B, LEU355B, LEU361B, LEU379D, LEU386D, LEU391D, LEU392D, LYS209B, LYS241D, LYS254B, LYS287D, LYS297B, LYS300B, LYS301D, LYS332D, LYS380B, LYS384D, LYS390D, LYS405D, LYS416D, MET192B, MET212B, MET259B, MET284B, MET307D, MET341D, MET383D, PHE298B, PHE348D, PHE349B, PHE350B, PHE357B, PHE365B, PHE379B, PHE381B, PHE388D, PHE414D, PHE415D, PRO210B, PRO211B, PRO222D, PRO232B, PRO269B, PRO272B, PRO285D, PRO307B, PRO347D, PRO368B, PRO399D, PRO401D, PRO407D, PRO411D, PRO421D, SER228D, SER235D, SER274B, SER286D, SER299B, SER326D, SER343D, SER351B, SER358B, SER376B, SER387D, THR153B, THR218B, THR233B, THR239D, THR372B, THR377B, THR382D, THR409D, THR429D, TRP217B, TRP240D, TRP346B, TRP373B, TRP424D, TYR260B, TYR265B, TYR305B, TYR332B, TYR370B, TYR371B, TYR412D, TYR431D, VAL196B, VAL204B, VAL236D, VAL281B, VAL282B, VAL285B, VAL301B, VAL302B, VAL303B, VAL304D, VAL346D, VAL349D, VAL400D, VAL404D, VAL420D
• B-E: ALA369B, ALA369E, ARG292B, ARG292E, ARG366B, ARG366E, ARG374B, ARG374E, ASN291B, ASN291E, ASP363B, ASP363E, ASP367B, ASP367E, GLN375B, GLN375E, GLN378B, GLN378E, GLU339B, GLU339E, GLU347B, GLU347E, GLY345B, GLY345E, ILE293B, ILE293E, LYS288B, LYS288E, LYS297B, LYS297E, LYS300B, LYS300E, MET295B, MET295E, PHE298B, PHE298E, PHE365B, PHE365E, PHE379B, PHE379E, PRO296B, PRO296E, PRO368B, PRO368E, SER290B, SER290E, SER294B, SER294E, SER376B, SER376E, THR372B, THR372E, THR377B, THR377E, TRP373B, TRP373E, TYR370B, TYR370E, TYR371B, TYR371E, VAL289B, VAL289E
• C-D: ARG21C, ARG437D, ASP14C, GLU15C, LEU20C, LEU436D, LYS100C
• D-E: ALA103D, ALA112D, ALA137E, ALA155E, ALA158E, ALA15E, ALA164E, ALA180E, ALA186D, ALA192D, ALA193D, ALA195E, ALA227D, ALA227E, ALA229E, ALA230D, ALA234E, ALA263D, ALA265D, ALA270E, ALA278D, ALA28D, ALA29D, ALA2E, ALA316D, ALA329E, ALA331D, ALA331E, ALA333D, ALA339D, ALA35E, ALA56E, ALA69E, ALA70E, ALA85E, ARG101D, ARG116D, ARG125D, ARG172D, ARG177E, ARG17E, ARG182D, ARG183E, ARG207D, ARG231D, ARG24E, ARG269D, ARG283D, ARG292E, ARG305D, ARG312E, ARG315D, ARG31D, ARG323D, ARG336E, ARG343E, ARG366E, ARG376D, ARG378D, ARG66E, ARG71E, ARG79E, ARG83D, ARG94E, ARG98E, ASN100E, ASN131D, ASN141E, ASN159D, ASN161D, ASN16E, ASN191E, ASN223D, ASN262D, ASN263E, ASN282D, ASN291E, ASN308E, ASN311D, ASN330E, ASN375D, ASN37E, ASN410D, ASN99E, ASN9E, ASP10D, ASP113D, ASP120D, ASP123D, ASP124E, ASP138D, ASP157E, ASP163D, ASP167E, ASP189D, ASP203D, ASP20E, ASP219D, ASP23D, ASP270D, ASP275D, ASP275E, ASP279E, ASP27E, ASP337D, ASP39D, ASP59D, ASP83E, ASP86D, ASP86E, CYS119D, CYS151E, CYS177D, CYS183D, CYS188E, CYS189E, CYS193E, CYS194D, CYS198E, CYS221D, CYS225D, CYS231E, CYS261E, CYS264E, CYS268E, CYS284D, CYS306D, CYS309D, CYS82E, CYS89E, GLN104D, GLN117D, GLN11D, GLN146E, GLN148D, GLN174E, GLN191D, GLN202D, GLN26D, GLN340D, GLN41D, GLU102E, GLU13D, GLU150D, GLU151D, GLU155D, GLU168E, GLU171E, GLU175D, GLU184D, GLU196D, GLU204D, GLU223E, GLU277E, GLU279D, GLU27D, GLU28E, GLU309E, GLU325E, GLU335E, GLU339E, GLU353D, GLU381D, GLU406D, GLU45E, GLU48E, GLU55D, GLU57E, GLU60D, GLU62D, GLU80E, GLY107D, GLY125E, GLY126D, GLY126E, GLY128D, GLY133E, GLY134D, GLY134E, GLY136E, GLY137D, GLY138E, GLY143D, GLY147E, GLY15D, GLY160E, GLY165D, GLY179D, GLY194E, GLY224D, GLY22E, GLY238D, GLY262E, GLY264D, GLY268D, GLY272D, GLY276E, GLY278E, GLY287E, GLY338D, GLY342D, GLY37D, GLY39E, GLY61D, GLY68D, GLY68E, GLY69D, GLY72D, GLY75D, GLY7E, GLY82D, GLY90E, GLY91E, HIS133D, HIS144E, HIS150E, HIS152E, HIS158D, HIS197E, HIS206D, HIS207E, HIS266D, HIS308D, HIS318D, HIS44E, HIS54E, HIS64D, HIS67D, HIS77E, HIS92E, HIS96D, HIS98D, ILE121D, ILE132E, ILE139D, ILE142E, ILE152D, ILE165E, ILE18E, ILE190E, ILE21E, ILE229D, ILE237D, ILE24D, ILE273E, ILE276D, ILE293E, ILE310D, ILE324E, ILE335D, ILE34E, ILE46E, ILE4E, ILE75E, ILE78E, ILE81D, ILE84E, LEU115D, LEU118D, LEU124D, LEU128E, LEU129D, LEU12D, LEU141D, LEU142D, LEU149D, LEU156D, LEU160D, LEU164D, LEU178D, LEU178E, LEU186E, LEU205D, LEU221E, LEU226E, LEU271E, LEU317D, LEU328D, LEU336D, LEU344D, LEU38D, LEU42E, LEU47E, LEU50D, LEU51D, LEU52E, LEU54D, LEU56D, LEU72E, LEU93E, LEU9D, LYS108D, LYS122E, LYS129E, LYS12E, LYS163E, LYS180D, LYS213D, LYS215D, LYS217D, LYS245D, LYS25D, LYS25E, LYS260D, LYS273D, LYS287D, LYS288E, LYS297E, LYS300E, LYS332D, LYS333E, LYS36D, LYS374D, LYS384D, LYS405D, LYS61E, LYS66D, LYS87E, LYS8D, MET104E, MET132D, MET14E, MET166E, MET176E, MET192E, MET199D, MET212E, MET259E, MET267E, MET284E, MET295E, MET307D, MET313D, MET341D, MET53E, MET73E, MET81E, PHE103E, PHE123E, PHE130E, PHE153D, PHE154D, PHE170E, PHE173E, PHE185D, PHE20D, PHE218D, PHE259D, PHE26E, PHE274D, PHE298E, PHE29E, PHE30E, PHE355D, PHE365E, PHE38E, PHE3E, PHE74D, PHE95E, PHE97D, PRO105D, PRO10E, PRO131E, PRO13E, PRO147D, PRO154E, PRO161E, PRO16D, PRO174D, PRO179E, PRO181E, PRO18D, PRO222D, PRO225E, PRO232E, PRO23E, PRO261D, PRO269E, PRO272E, PRO285D, PRO296E, PRO310E, PRO311E, PRO314D, PRO31E, PRO334D, PRO35D, PRO368E, PRO47D, PRO49E, PRO7D, SER106D, SER111D, SER127D, SER127E, SER135D, SER140E, SER14D, SER159E, SER175E, SER176D, SER181D, SER185E, SER190D, SER199E, SER19D, SER228D, SER22D, SER230E, SER232D, SER267D, SER274E, SER286D, SER290E, SER294E, SER299E, SER326D, SER328E, SER40E, SER57D, SER5E, SER6E, SER74E, THR130D, THR135E, THR136D, THR144D, THR145E, THR153E, THR156E, THR157D, THR162D, THR173D, THR198D, THR19E, THR233E, THR266E, THR312D, THR317E, THR409D, THR63D, THR64E, THR6D, THR76E, THR96E, THR97E, THR99D, TRP122D, TRP148E, TRP17D, TRP271D, TRP313E, TRP340E, TRP41E, TRP65D, TYR109D, TYR110D, TYR114D, TYR188D, TYR195D, TYR201D, TYR212D, TYR254D, TYR265E, TYR30D, TYR327E, TYR332E, TYR334E, TYR370E, TYR371E, TYR40D, TYR43E, TYR58D, TYR63E, TYR76D, TYR84D, TYR8E, VAL100D, VAL101E, VAL102D, VAL139E, VAL140D, VAL143E, VAL149E, VAL162E, VAL169E, VAL196E, VAL204E, VAL21D, VAL226D, VAL228E, VAL280D, VAL289E, VAL304D, VAL33E, VAL404D, VAL42D, VAL51E, VAL53D, VAL55E, VAL62E, VAL65E, VAL67E, VAL73D, VAL80D, VAL94D
• D-F: ALA209D, ALA63F, ALA95D, ARG101D, ARG172D, ARG207D, ARG376D, ARG378D, ARG385D, ARG67F, ARG83D, ASN170D, ASN375D, ASP14F, ASP16F, ASP203D, ASP367D, ASP86D, CYS104F, CYS85D, CYS93F, GLU150D, GLU15F, GLU204D, GLU35F, GLU371D, GLU372D, GLU377D, GLU37F, GLU79F, GLU82F, GLY103F, GLY166D, GLY168D, GLY17F, GLY373D, GLY38F, GLY68D, GLY69D, GLY72D, GLY75D, GLY77D, GLY78D, GLY79D, GLY82D, GLY87F, GLY89F, GLY91F, HIS206D, HIS67D, HIS96D, HIS98D, ILE39F, ILE62F, ILE68F, ILE70D, ILE81D, LEU149D, LEU77F, LEU83F, LYS100F, LYS213D, LYS34F, LYS374D, LYS66D, LYS71F, LYS76F, LYS78F, LYS90F, LYS94F, MET370D, MET65F, PHE18F, PHE210D, PHE74D, PHE84F, PRO101F, PRO208D, PRO211D, PRO64F, PRO85F, PRO88D, PRO88F, PRO99F, SER167D, SER169D, SER36F, SER70F, SER86F, THR102F, THR146D, THR382D, TRP366D, TRP368D, TRP369D, TYR212D, TYR56F, TYR76D, TYR81F, TYR84D, VAL105F, VAL33F, VAL66F, VAL71D, VAL73D, VAL80D, VAL80F
• E-F: ALA227E, ALA229E, ALA270E, ALA63F, ARG17E, ARG21F, ASN191E, ASN263E, ASN60F, ASP14F, ASP219E, ASP23F, ASP24F, CYS104F, CYS151E, CYS193E, CYS222E, CYS264E, CYS268E, CYS93F, GLN220E, GLU11E, GLU12F, GLU216E, GLU223E, GLU35F, GLU37F, GLU82F, GLY103F, GLY38F, GLY61F, GLY97F, HIS152E, ILE224E, ILE39F, ILE62F, LEU19F, LEU20F, LEU221E, LEU226E, LEU98F, LYS100F, LYS12E, LYS246E, LYS34F, LYS59F, MET14E, MET267E, MET65F, PHE18F, PHE22F, PHE84F, PRO101F, PRO10E, PRO13E, PRO225E, PRO269E, PRO64F, PRO85F, PRO99F, SER36F, SER40F, SER86F, THR102F, THR153E, THR218E, THR266E, TRP217E, TYR265E, TYR56F, TYR57F, TYR81F, TYR8E, VAL105F, VAL228E