2V0Z

crystal structure of renin with inhibitor 10 (aliskiren)

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: C-O
  • Int. Res.: 110
  • Norm. En. per Res.: -1.3598
• Hub Node: C(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
C-O	-19.8067	2.0556	-131.831	-149.5821	110	4	0	6353	0	22	19

Interface residues

• C-O: ALA272C, ALA325C, ARG157C, ARG307C, ARG326C, ARG326O, ASN-1O, ASN156C, ASN156O, ASN178C, ASN250C, ASN8C, ASN8O, ASP118O, ASP11C, ASP11O, ASP158C, ASP158O, ASP171O, ASP257C, ASP273C, CYS249C, GLN13O, GLN160C, GLN160O, GLN164O, GLN173C, GLN173O, GLN25O, GLN277C, GLU116O, GLU176C, GLU17O, GLU266C, GLU278C, GLY162O, GLY163O, GLY169O, GLY16O, GLY177C, GLY200C, GLY252C, GLY264C, GLY92O, GLY93O, HIS174C, HIS174O, HIS261C, ILE165O, ILE18O, ILE258C, ILE5O, ILE94O, LEU146O, LEU161C, LEU161O, LEU167O, LEU255C, LEU269C, LEU324C, LEU55O, LEU6O, LYS265C, LYS28O, LYS308C, LYS54O, MET10C, MET10O, PHE276C, PHE27O, PHE309C, PRO172O, PRO23O, PRO24O, PRO253C, PRO256C, SER159C, SER160C, SER160O, SER201C, SER259C, SER271C, SER279C, SER2O, SER3O, THR0O, THR12C, THR12O, THR1O, THR22O, THR254C, THR268C, THR26O, THR270C, THR7O, THR90O, THR95O, TYR154C, TYR15O, TYR175C, TYR267C, TYR274C, TYR280C, TYR52O, TYR9C, TYR9O, VAL166O, VAL275C, VAL4O, VAL91O