2UX8

crystal structure of sphingomonas elodea atcc 31461 glucose- 1-phosphate uridylyltransferase in complex with glucose- 1-phosphate.

• Total interactions analyzed: 28
• Total true interactions: 12
• Strongest Interaction:
  • Chains: G-H
  • Int. Res.: 111
  • Norm. En. per Res.: -5.1514
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	1.3101	-43.9352	-42.6251	28	0	1	1170	0	0	13
A-C	-101.9784	-93.2898	-521.582	-716.8502	193	49	41	26760	7	54	43
A-D	-86.6493	-156.6705	-286.208	-529.5278	107	18	8	12069	12	42	46
B-C	-98.286	-166.7508	-313.309	-578.3458	113	17	11	13375	14	47	43
B-D	-112.6556	-95.1828	-513.534	-721.3725	199	50	41	26891	7	56	44
C-D	0.0	1.2478	-54.0717	-52.8239	28	1	1	1298	0	0	13
E-F	-108.209	-139.6327	-265.812	-513.6537	106	20	9	11836	10	40	45
E-G	0.0	1.1501	-44.5365	-43.3864	30	3	1	1248	0	0	13
E-H	-91.0801	-89.0335	-539.735	-719.8485	196	45	41	26971	8	55	40
F-G	-118.5704	-88.742	-502.756	-710.0683	198	42	39	26351	7	55	41
F-H	0.0	1.3013	-44.6234	-43.3221	29	0	1	1196	0	0	13
G-H	-97.2255	-152.5433	-322.038	-571.8068	111	23	11	13013	12	51	44

Interface residues

• A-B: ALA26A, ALA26B, ALA73A, ALA73B, ALA78A, ALA78B, ALA81B, ALA82A, ALA82B, ARG104A, ARG104B, ARG61B, ASP71B, GLN106B, GLU75A, GLU75B, GLU77A, GLU77B, ILE72A, ILE72B, LEU76A, LEU76B, LYS25A, MET80B, THR79A, THR79B, TYR74A, TYR74B
• A-C: ALA23A, ALA23C, ALA260A, ALA260C, ALA265A, ALA265C, ALA268A, ALA268C, ALA26A, ALA26C, ALA270A, ALA270C, ALA279A, ALA279C, ALA282A, ALA282C, ALA284A, ALA284C, ALA287A, ALA287C, ALA65A, ALA65C, ALA73A, ALA73C, ALA78A, ALA78C, ARG19A, ARG19C, ARG273A, ARG273C, ARG281A, ARG281C, ARG37A, ARG37C, ARG61A, ARG61C, ARG83A, ARG83C, ARG94A, ARG94C, ASN266A, ASN266C, ASP258A, ASP258C, ASP275A, ASP275C, ASP36A, ASP36C, ASP45A, ASP45C, ASP68A, ASP68C, ASP71A, ASP71C, ASP88A, ASP88C, ASP91A, ASP91C, GLN106A, GLN106C, GLN264A, GLN264C, GLN41A, GLN41C, GLU107A, GLU107C, GLU277A, GLU277C, GLU67A, GLU67C, GLU75A, GLU75C, GLU77A, GLU77C, GLY110A, GLY110C, GLY15A, GLY15C, GLY17A, GLY17C, GLY261A, GLY261C, GLY289A, GLY289C, GLY60A, GLY62A, GLY62C, GLY92A, GLY92C, HIS69A, HIS69C, ILE263A, ILE263C, ILE40A, ILE40C, ILE72A, ILE72C, LEU16A, LEU16C, LEU21A, LEU21C, LEU267A, LEU267C, LEU271A, LEU271C, LEU276A, LEU276C, LEU288A, LEU288C, LEU32A, LEU32C, LEU66A, LEU66C, LEU76A, LEU76C, LEU87A, LEU87C, LEU90A, LEU90C, LEU95C, LYS259A, LYS259C, LYS25A, LYS25C, LYS286A, LYS286C, LYS29A, LYS85A, LYS85C, MET109A, MET109C, MET27A, MET27C, MET31A, MET31C, MET80A, MET80C, PHE137A, PHE137C, PHE20A, PHE20C, PHE262A, PHE262C, PHE283A, PHE283C, PHE70A, PHE70C, PRO108A, PRO108C, PRO22A, PRO22C, PRO278A, PRO278C, PRO28A, PRO28C, PRO33A, PRO33C, PRO38A, PRO38C, SER272A, SER272C, SER64A, SER64C, SER86A, SER86C, THR18A, THR18C, THR24A, THR24C, THR252A, THR252C, THR79A, THR79C, THR93A, THR93C, TYR254A, TYR254C, TYR42A, TYR42C, TYR74A, TYR74C, VAL269A, VAL269C, VAL280A, VAL280C, VAL285A, VAL285C, VAL34A, VAL34C, VAL35A, VAL35C, VAL89A, VAL89C
• A-D: ALA101A, ALA101D, ALA114A, ALA114D, ALA118A, ALA118D, ALA65A, ALA65D, ALA73A, ALA73D, ARG104A, ARG104D, ARG119A, ARG119D, ARG61A, ARG61D, ARG7A, ARG7D, ARG94A, ARG94D, ASN99A, ASN99D, ASP120A, ASP120D, ASP68A, ASP68D, ASP71A, ASP71D, CYS117A, CYS117D, GLN105A, GLN105D, GLN106A, GLN106D, GLN54A, GLN54D, GLU107A, GLU107D, GLU125A, GLU53A, GLU53D, GLU67A, GLU67D, GLU75A, GLU75D, GLU77A, GLY123A, GLY123D, GLY222A, GLY60A, GLY60D, GLY62A, GLY62D, GLY98A, GLY98D, HIS113A, HIS113D, HIS69A, HIS69D, ILE100A, ILE100D, ILE121A, ILE121D, ILE56A, ILE56D, ILE72A, ILE72D, LEU66A, LEU66D, LEU95A, LEU95D, LYS63A, LYS63D, LYS8A, LYS8D, LYS96A, LYS96D, MET109A, MET109D, MET55A, MET55D, PHE57A, PHE57D, PHE70A, PHE70D, PRO108A, PRO108D, PRO97A, PRO97D, SER64A, SER64D, THR59A, THR59D, THR93A, THR93D, TRP116A, TRP116D, TYR102A, TYR102D, TYR74A, TYR74D, VAL103A, VAL103D, VAL122A, VAL122D, VAL58A, VAL58D
• B-C: ALA101B, ALA101C, ALA114B, ALA114C, ALA118B, ALA118C, ALA65B, ALA65C, ALA73B, ALA73C, ARG104B, ARG104C, ARG119B, ARG119C, ARG216B, ARG216C, ARG61B, ARG61C, ARG7B, ARG7C, ARG94B, ARG94C, ASN99B, ASN99C, ASP120B, ASP120C, ASP124B, ASP68B, ASP68C, ASP71B, ASP71C, CYS117B, CYS117C, GLN105B, GLN105C, GLN106B, GLN106C, GLN54B, GLN54C, GLU107B, GLU107C, GLU125B, GLU125C, GLU219B, GLU53B, GLU53C, GLU67B, GLU67C, GLU75B, GLU75C, GLY123B, GLY123C, GLY222B, GLY222C, GLY60B, GLY60C, GLY62B, GLY62C, GLY98B, GLY98C, HIS113B, HIS113C, HIS69B, HIS69C, ILE100B, ILE100C, ILE121B, ILE121C, ILE56B, ILE56C, ILE72B, ILE72C, LEU66B, LEU66C, LEU95B, LEU95C, LYS4C, LYS63B, LYS63C, LYS8B, LYS8C, LYS96B, LYS96C, MET109B, MET109C, MET55B, MET55C, PHE57B, PHE57C, PHE70B, PHE70C, PRO108B, PRO108C, PRO97B, PRO97C, SER64B, SER64C, THR59B, THR59C, THR93B, THR93C, TRP116B, TRP116C, TYR102B, TYR102C, TYR74B, TYR74C, VAL103B, VAL103C, VAL122B, VAL122C, VAL58B, VAL58C
• B-D: ALA23B, ALA23D, ALA260B, ALA260D, ALA265B, ALA265D, ALA268B, ALA268D, ALA26B, ALA26D, ALA270B, ALA270D, ALA279B, ALA279D, ALA282B, ALA282D, ALA284B, ALA284D, ALA287B, ALA287D, ALA65B, ALA65D, ALA73B, ALA73D, ALA78B, ALA78D, ARG19B, ARG19D, ARG273B, ARG273D, ARG281B, ARG281D, ARG37B, ARG37D, ARG61B, ARG61D, ARG83B, ARG83D, ARG94B, ARG94D, ASN266B, ASN266D, ASP258B, ASP258D, ASP275B, ASP275D, ASP36B, ASP36D, ASP45B, ASP45D, ASP68B, ASP68D, ASP71B, ASP71D, ASP88B, ASP88D, ASP91B, ASP91D, GLN106B, GLN106D, GLN264B, GLN264D, GLN41B, GLN41D, GLU107B, GLU107D, GLU277B, GLU277D, GLU30B, GLU67B, GLU67D, GLU75B, GLU75D, GLU77B, GLU77D, GLY110B, GLY110D, GLY15B, GLY17B, GLY17D, GLY261B, GLY261D, GLY289B, GLY289D, GLY60B, GLY60D, GLY62B, GLY62D, GLY92B, GLY92D, HIS69B, HIS69D, ILE263B, ILE263D, ILE40B, ILE72B, ILE72D, LEU16B, LEU16D, LEU21B, LEU21D, LEU267B, LEU267D, LEU271B, LEU271D, LEU276B, LEU276D, LEU288B, LEU288D, LEU32B, LEU32D, LEU39B, LEU39D, LEU66B, LEU66D, LEU76B, LEU76D, LEU87B, LEU87D, LEU90B, LEU90D, LEU95B, LEU95D, LYS259B, LYS259D, LYS25B, LYS25D, LYS286B, LYS286D, LYS29B, LYS29D, LYS63B, LYS63D, LYS85B, LYS85D, MET109B, MET109D, MET27B, MET27D, MET31B, MET31D, MET80B, MET80D, PHE137B, PHE137D, PHE20B, PHE20D, PHE262B, PHE262D, PHE283B, PHE283D, PHE70B, PHE70D, PRO108B, PRO108D, PRO22B, PRO22D, PRO278B, PRO278D, PRO28B, PRO28D, PRO33B, PRO33D, PRO38B, PRO38D, SER272B, SER272D, SER64B, SER64D, SER86B, SER86D, THR18B, THR18D, THR24B, THR24D, THR252B, THR252D, THR79B, THR79D, THR93B, THR93D, TYR254B, TYR254D, TYR42B, TYR42D, TYR74B, TYR74D, VAL269B, VAL269D, VAL280B, VAL280D, VAL285B, VAL285D, VAL34B, VAL34D, VAL35B, VAL35D, VAL89B, VAL89D
• C-D: ALA26C, ALA26D, ALA73C, ALA73D, ALA78C, ALA78D, ALA81D, ALA82C, ALA82D, ARG104C, ARG104D, ARG61C, ARG61D, GLN106C, GLU75C, GLU75D, GLU77C, GLU77D, ILE72C, ILE72D, LEU76C, LEU76D, LYS25C, LYS25D, THR79C, THR79D, TYR74C, TYR74D
• E-F: ALA101E, ALA101F, ALA114E, ALA114F, ALA118E, ALA118F, ALA65E, ALA65F, ALA73E, ALA73F, ARG104E, ARG104F, ARG119E, ARG119F, ARG61E, ARG61F, ARG94E, ARG94F, ASN99E, ASN99F, ASP120E, ASP120F, ASP68E, ASP68F, ASP71E, ASP71F, CYS117E, CYS117F, GLN105E, GLN105F, GLN106E, GLN106F, GLN54E, GLN54F, GLU107E, GLU107F, GLU125E, GLU53E, GLU53F, GLU67E, GLU67F, GLU75E, GLU75F, GLU77F, GLY123E, GLY123F, GLY222F, GLY60E, GLY60F, GLY62E, GLY62F, GLY98E, GLY98F, HIS113E, HIS113F, HIS69E, HIS69F, ILE100E, ILE100F, ILE121E, ILE121F, ILE56E, ILE56F, ILE72E, ILE72F, LEU16E, LEU66E, LEU66F, LEU95E, LEU95F, LYS63E, LYS63F, LYS8E, LYS8F, LYS96E, LYS96F, MET109E, MET109F, MET55E, MET55F, PHE57E, PHE57F, PHE70E, PHE70F, PRO108E, PRO108F, PRO97E, PRO97F, SER64E, SER64F, THR59E, THR59F, THR93E, THR93F, TRP116E, TRP116F, TYR102E, TYR102F, TYR74E, TYR74F, VAL103E, VAL103F, VAL122E, VAL122F, VAL58E, VAL58F
• E-G: ALA26E, ALA26G, ALA73E, ALA73G, ALA78E, ALA78G, ALA81G, ALA82E, ALA82G, ARG104E, ARG104G, ARG61E, ARG61G, GLN106E, GLN106G, GLU75E, GLU75G, GLU77E, GLU77G, ILE72E, ILE72G, LEU76E, LEU76G, LYS25E, LYS25G, MET80G, THR79E, THR79G, TYR74E, TYR74G
• E-H: ALA23E, ALA23H, ALA260E, ALA260H, ALA265E, ALA265H, ALA268E, ALA268H, ALA26E, ALA26H, ALA270E, ALA270H, ALA279E, ALA279H, ALA282E, ALA282H, ALA284E, ALA284H, ALA287E, ALA287H, ALA65E, ALA65H, ALA73E, ALA73H, ALA78E, ALA78H, ARG19E, ARG19H, ARG253E, ARG253H, ARG273E, ARG273H, ARG281E, ARG281H, ARG37E, ARG37H, ARG61E, ARG61H, ARG83E, ARG83H, ARG94E, ARG94H, ASN266E, ASN266H, ASP258E, ASP258H, ASP275E, ASP275H, ASP36E, ASP36H, ASP45E, ASP45H, ASP68E, ASP68H, ASP71E, ASP71H, ASP88E, ASP88H, ASP91E, ASP91H, GLN106E, GLN106H, GLN264E, GLN264H, GLN41E, GLN41H, GLU107E, GLU107H, GLU277E, GLU277H, GLU67E, GLU67H, GLU75E, GLU75H, GLU77E, GLU77H, GLY110E, GLY110H, GLY15E, GLY15H, GLY17E, GLY17H, GLY261E, GLY261H, GLY289E, GLY289H, GLY60E, GLY60H, GLY62E, GLY62H, GLY92E, GLY92H, HIS69E, HIS69H, ILE263E, ILE263H, ILE40E, ILE40H, ILE72E, ILE72H, LEU16E, LEU16H, LEU21E, LEU21H, LEU267E, LEU267H, LEU271E, LEU271H, LEU276E, LEU276H, LEU288E, LEU288H, LEU32E, LEU32H, LEU66E, LEU66H, LEU76E, LEU76H, LEU87E, LEU87H, LEU90E, LEU90H, LEU95E, LEU95H, LYS259E, LYS259H, LYS25E, LYS25H, LYS286E, LYS286H, LYS29E, LYS29H, LYS85E, LYS85H, MET109E, MET109H, MET27E, MET27H, MET31E, MET31H, MET80E, MET80H, PHE137E, PHE137H, PHE20E, PHE20H, PHE262E, PHE262H, PHE283E, PHE283H, PHE70E, PHE70H, PRO108E, PRO108H, PRO22E, PRO22H, PRO278E, PRO278H, PRO28E, PRO28H, PRO33E, PRO33H, PRO38E, PRO38H, SER64E, SER64H, SER86E, SER86H, THR18E, THR18H, THR24E, THR24H, THR252E, THR252H, THR79E, THR79H, THR93E, THR93H, TYR254E, TYR254H, TYR42E, TYR42H, TYR74E, TYR74H, VAL269E, VAL269H, VAL280E, VAL280H, VAL285E, VAL285H, VAL34E, VAL34H, VAL35E, VAL35H, VAL89E, VAL89H
• F-G: ALA23F, ALA23G, ALA260F, ALA260G, ALA265F, ALA265G, ALA268F, ALA268G, ALA26F, ALA26G, ALA270F, ALA270G, ALA279F, ALA279G, ALA282F, ALA282G, ALA284F, ALA284G, ALA287F, ALA287G, ALA65F, ALA65G, ALA73F, ALA73G, ALA78F, ALA78G, ARG19F, ARG19G, ARG253F, ARG273F, ARG273G, ARG281F, ARG281G, ARG37F, ARG37G, ARG61F, ARG61G, ARG83F, ARG83G, ARG94F, ARG94G, ASN266F, ASN266G, ASP258F, ASP258G, ASP275F, ASP275G, ASP36F, ASP36G, ASP45F, ASP45G, ASP68F, ASP68G, ASP71F, ASP71G, ASP88F, ASP88G, ASP91F, ASP91G, GLN106F, GLN106G, GLN264F, GLN264G, GLN41F, GLN41G, GLU107F, GLU107G, GLU277F, GLU277G, GLU30F, GLU30G, GLU67F, GLU67G, GLU75F, GLU75G, GLU77F, GLU77G, GLY110F, GLY15F, GLY15G, GLY17F, GLY17G, GLY261F, GLY261G, GLY289F, GLY289G, GLY60F, GLY62F, GLY62G, GLY92F, GLY92G, HIS69F, HIS69G, ILE263F, ILE263G, ILE40F, ILE40G, ILE72F, ILE72G, LEU16F, LEU16G, LEU21F, LEU21G, LEU267F, LEU267G, LEU271F, LEU271G, LEU276F, LEU276G, LEU288F, LEU288G, LEU32F, LEU32G, LEU39G, LEU66F, LEU66G, LEU76F, LEU76G, LEU87F, LEU87G, LEU90F, LEU90G, LEU95F, LEU95G, LYS259F, LYS259G, LYS25F, LYS25G, LYS286F, LYS286G, LYS29F, LYS29G, LYS63F, LYS85F, LYS85G, MET109F, MET109G, MET27F, MET27G, MET31F, MET31G, MET80F, MET80G, PHE137F, PHE137G, PHE20F, PHE20G, PHE262F, PHE262G, PHE283F, PHE283G, PHE70F, PHE70G, PRO108F, PRO108G, PRO22F, PRO22G, PRO278F, PRO278G, PRO28F, PRO28G, PRO33F, PRO33G, PRO38F, PRO38G, SER272G, SER64F, SER64G, SER86F, SER86G, THR18F, THR18G, THR24F, THR24G, THR252F, THR252G, THR79F, THR79G, THR93F, THR93G, TYR254F, TYR254G, TYR42F, TYR42G, TYR74F, TYR74G, VAL269F, VAL269G, VAL280F, VAL280G, VAL285F, VAL285G, VAL34F, VAL34G, VAL35F, VAL35G, VAL89F, VAL89G
• F-H: ALA26F, ALA26H, ALA73F, ALA73H, ALA78F, ALA78H, ALA82F, ALA82H, ARG104F, ARG104H, ARG61F, ARG61H, GLN106F, GLN106H, GLU75F, GLU75H, GLU77F, GLU77H, ILE72F, ILE72H, LEU76F, LEU76H, LYS25F, LYS25H, MET80H, THR79F, THR79H, TYR74F, TYR74H
• G-H: ALA101G, ALA101H, ALA114G, ALA114H, ALA118G, ALA118H, ALA225G, ALA65G, ALA65H, ALA73G, ALA73H, ARG104G, ARG104H, ARG119G, ARG119H, ARG61G, ARG61H, ARG7G, ARG7H, ARG94G, ARG94H, ASN99G, ASN99H, ASP120G, ASP120H, ASP124G, ASP68G, ASP68H, ASP71G, ASP71H, CYS117G, CYS117H, GLN105G, GLN105H, GLN106G, GLN106H, GLN54G, GLN54H, GLU107G, GLU107H, GLU125G, GLU125H, GLU219H, GLU53G, GLU53H, GLU67G, GLU67H, GLU75G, GLU75H, GLY123G, GLY123H, GLY226G, GLY227G, GLY60G, GLY60H, GLY62G, GLY62H, GLY98G, GLY98H, HIS113G, HIS113H, HIS69G, HIS69H, ILE100G, ILE100H, ILE121G, ILE121H, ILE56G, ILE56H, ILE72G, ILE72H, LEU66G, LEU66H, LEU95G, LEU95H, LYS63G, LYS63H, LYS8G, LYS8H, LYS96G, LYS96H, MET109G, MET109H, MET55G, MET55H, PHE57G, PHE57H, PHE70G, PHE70H, PRO108G, PRO108H, PRO97G, PRO97H, SER64G, SER64H, THR59G, THR59H, THR93G, THR93H, TRP116G, TRP116H, TYR102G, TYR102H, TYR74G, TYR74H, VAL103G, VAL103H, VAL122G, VAL122H, VAL58G, VAL58H