2UVC

crystal structure of fatty acid synthase complexed with nadp+ from thermomyces lanuginosus at 3.1 angstrom resolution. this file contains the beta subunits of the fatty acid synthase. the entire crystal structure consists of one heterododecameric fatty acid synthase and is described in remark 400

• Total interactions analyzed: 15
• Total true interactions: 6
• Strongest Interaction:
  • Chains: G-I
  • Int. Res.: 117
  • Norm. En. per Res.: -1.3151
• Hub Node: J(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
G-H	0.0	-6.1412	-121.758	-127.8992	108	27	0	6222	1	21	28
G-I	-4.19	-5.5486	-144.126	-153.8646	117	28	0	7125	1	22	29
H-I	0.0	3.1296	-107.082	-103.9523	108	55	0	6972	1	22	26
J-K	-10.0559	-3.3262			10
J-L	-4.3358	-5.1212			9
K-L	-15.1428	-8.0844			10

Interface residues

• G-H: ALA1322H, ALA1327H, ALA1334H, ALA1575H, ALA1624H, ALA1625H, ALA325G, ALA332G, ALA437G, ALA46G, ALA46H, ALA94G, ARG1338H, ARG1572H, ARG1582H, ARG22G, ARG22H, ARG328G, ARG376G, ASN1330H, ASN1579H, ASN1627H, ASN1628H, ASN1646H, ASP1323H, ASP1337H, ASP1341H, ASP239G, ASP375G, ASP91G, ASP93G, GLN1319H, GLN220G, GLN229G, GLN323G, GLN324G, GLN337G, GLN44G, GLN47G, GLU1333H, GLU1621H, GLU1626H, GLY1329H, GLY1332H, GLY1339H, GLY1565H, HIS1326H, HIS371G, HIS42G, HIS42H, ILE396G, LEU1563H, LEU1569H, LEU1619H, LEU21H, LEU24H, LEU331G, LEU336G, LEU36H, LEU372G, LEU41G, LEU444G, LYS1340H, LYS1566H, LYS219G, LYS223G, LYS49H, PHE1324H, PHE1335H, PHE43G, PHE43H, PRO1150H, PRO1574H, PRO222G, PRO23H, PRO327G, PRO333G, PRO349G, PRO373G, PRO394G, PRO395G, PRO438G, SER1564H, SER1618H, SER322G, SER330G, SER334G, SER34H, SER40G, SER51G, THR1331H, THR1567H, THR1622H, THR329G, THR335G, THR39G, THR39H, THR436G, THR97G, TRP1623H, TRP215G, TYR326G, TYR443G, VAL1325H, VAL1336H, VAL1583H, VAL218G, VAL25H
• G-I: ALA1322G, ALA1327G, ALA1334G, ALA1575G, ALA1624G, ALA1625G, ALA325I, ALA332I, ALA437I, ALA46G, ALA46I, ALA94I, ARG1338G, ARG1572G, ARG1582G, ARG22G, ARG22I, ARG328I, ARG376I, ASN1330G, ASN1579G, ASN1627G, ASN1628G, ASN1646G, ASN98I, ASP1323G, ASP1337G, ASP1341G, ASP239I, ASP375I, ASP50G, ASP50I, ASP91I, ASP93I, GLN1319G, GLN19G, GLN220I, GLN323I, GLN324I, GLN337I, GLN44I, GLN47I, GLU1333G, GLU1621G, GLU1626G, GLU32G, GLU92I, GLY1329G, GLY1332G, GLY1339G, GLY1565G, HIS1326G, HIS371I, HIS42G, HIS42I, HIS95I, ILE396I, LEU1563G, LEU1569G, LEU1619G, LEU21G, LEU24G, LEU331I, LEU336I, LEU36G, LEU372I, LEU41I, LEU444I, LEU48I, LYS1340G, LYS219I, LYS223I, LYS49G, PHE1335G, PHE35G, PHE43G, PHE43I, PRO1574G, PRO222I, PRO23G, PRO327I, PRO333I, PRO349I, PRO373I, PRO38I, PRO394I, PRO395I, PRO438I, PRO96I, SER1564G, SER1618G, SER322I, SER330I, SER334I, SER34G, SER397I, SER40I, SER51I, THR1331G, THR1567G, THR1622G, THR27G, THR329I, THR335I, THR39G, THR39I, THR436I, THR97I, TRP1623G, TRP215I, TYR326I, TYR443I, VAL1325G, VAL1336G, VAL1583G, VAL218I, VAL25G
• H-I: ALA1322I, ALA1327I, ALA1334I, ALA1624I, ALA1625I, ALA325H, ALA332H, ALA437H, ALA45H, ALA46H, ALA46I, ALA94H, ARG1338I, ARG1572I, ARG1582I, ARG22H, ARG22I, ARG328H, ARG376H, ASN1330I, ASN1579I, ASN1627I, ASN1628I, ASP1323I, ASP1337I, ASP1341I, ASP239H, ASP375H, ASP50H, ASP91H, ASP93H, GLN1319I, GLN19I, GLN220H, GLN323H, GLN324H, GLN337H, GLN44H, GLN47H, GLU1333I, GLU1621I, GLU1626I, GLY1329I, GLY1332I, GLY1339I, GLY1565I, HIS1326I, HIS371H, HIS42H, HIS42I, ILE396H, LEU1563I, LEU1569I, LEU1619I, LEU21I, LEU24I, LEU331H, LEU336H, LEU36I, LEU372H, LEU41H, LEU444H, LEU48H, LYS1340I, LYS219H, LYS223H, PHE1335I, PHE35I, PHE43H, PHE43I, PRO1574I, PRO222H, PRO23I, PRO327H, PRO333H, PRO349H, PRO373H, PRO38I, PRO394H, PRO395H, PRO438H, PRO96H, SER1564I, SER1618I, SER20I, SER322H, SER330H, SER334H, SER34I, SER40H, SER51H, THR1331I, THR1567I, THR1622I, THR329H, THR335H, THR39H, THR39I, THR436H, THR97H, TRP1623I, TRP215H, TYR326H, TYR443H, VAL1336I, VAL218H, VAL25I, VAL37I
• J-K: ARG376J, ASN1627K, ASP1323K, GLU1333K, HIS1326K, LEU331J, LYS1340K, LYS219J, SER330J, THR1331K
• J-L: ARG1338J, ARG376L, ASP1323J, ASP375L, GLU1333J, HIS1326J, LYS1340J, LYS219L, THR329L
• K-L: ARG376K, ASN1627L, ASP1323L, GLU1333L, HIS1326L, LEU331K, LYS1340L, LYS219K, SER330K, THR1331L