2UVB

crystal structure of fatty acid synthase complexed with nadp+ from thermomyces lanuginosus at 3.1 angstrom resolution. this file contains the alpha subunits of the fatty acid synthase. the entire crystal structure consists of one heterododecameric fatty acid synthase and is described in remark 400

• Total interactions analyzed: 15
• Total true interactions: 15
• Strongest Interaction:
  • Chains: A-E
  • Int. Res.: 147
  • Norm. En. per Res.: -5.3518
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-2.4019	14.7399	-77.1817	-64.8438	59	1	1	3376	4	32	28
A-C	-2.1186	12.5389	-73.2966	-62.8762	59	1	1	3320	3	32	28
A-D	-22.7493	-7.9332	-87.6813	-118.3638	43	5	4	4113	0	8	9
A-E	-364.0724	-422.5881	-0.0574	-786.7179	147	0	0	29	0	0	0
A-F	-130.3573	-197.4702			73
B-C	0.0	13.5834	-75.0168	-61.4334	57	1	1	3387	4	32	28
B-D	-359.0772	-404.1372	-2207.86	-2971.0744	610	197	50	90041	37	227	260
B-E	-98.0507	-217.744	-780.63	-1096.4247	310	69	37	36596	4	66	82
B-F	-23.2726	-7.986			10
C-D	-105.3224	-213.0314	-1290.91	-1609.2638	412	111	47	55811	21	139	152
C-E	-22.1819	-7.8484	-84.4421	-114.4724	43	6	4	4053	0	8	9
C-F	-362.4981	-436.0538			143
D-E	-2.569	11.7859	-69.4802	-60.2633	59	1	1	3235	3	31	28
D-F	-2.3103	15.6559			14
E-F	-2.2112	14.5802			14

Interface residues

• A-B: ALA334B, ALA353B, ALA357B, ALA360B, ARG1141A, ARG1143A, ARG333A, ARG345B, ARG352B, ASP1105A, ASP1125A, ASP326A, ASP331B, ASP350B, ASP355B, GLN1104A, GLN332A, GLN332B, GLN338B, GLN339A, GLN339B, GLU1103A, GLU1107A, GLU1128A, GLU1131A, GLU341B, GLU363B, GLY1124A, GLY354B, ILE1129A, ILE325A, ILE325B, ILE342B, ILE343A, LEU1106A, LEU328A, LEU328B, LEU335A, LEU335B, LEU351B, LYS1113A, LYS1120A, LYS1126A, LYS1144A, LYS337B, LYS348B, LYS356B, LYS366B, PHE1130A, PHE336A, PHE336B, PHE358B, PRO1108A, THR1139A, THR329A, THR329B, TYR1138A, VAL1127A, VAL359B
• A-C: ALA327C, ALA334A, ALA353A, ALA357A, ALA360A, ARG1141C, ARG1143C, ARG333C, ARG345A, ARG352A, ASP1105C, ASP1125C, ASP326C, ASP331A, ASP350A, ASP355A, GLN1104C, GLN332A, GLN332C, GLN338A, GLN339A, GLN339C, GLU1103C, GLU1107C, GLU1128C, GLU1131C, GLU341A, GLU363A, GLY1124C, GLY354A, ILE1129C, ILE325A, ILE325C, ILE343C, LEU1106C, LEU328A, LEU328C, LEU335A, LEU335C, LEU351A, LYS1113C, LYS1120C, LYS1126C, LYS1144C, LYS337A, LYS348A, LYS356A, LYS366A, PHE1130C, PHE336A, PHE336C, PHE358A, PRO1108C, THR1139C, THR329A, THR329C, TYR1138C, VAL1127C, VAL359A
• A-D: ALA327A, ALA334A, ALA334D, ALA344A, ALA344D, ARG333A, ARG333D, ARG345A, ARG345D, ASP331A, ASP331D, GLN332A, GLN332D, GLN338A, GLN338D, GLN339A, GLN339D, GLU341A, GLU341D, ILE342A, ILE342D, ILE343A, ILE343D, LEU328A, LEU328D, LEU335A, LEU335D, LEU340A, LEU340D, LEU347A, LEU347D, LYS330A, LYS330D, LYS337A, LYS337D, LYS348A, LYS348D, PHE336A, PHE336D, THR329A, THR329D, TYR346A, TYR346D
• A-E: ALA1153A, ALA1153E, ALA1299A, ARG1093A, ARG1093E, ARG1121A, ARG1121E, ARG1239A, ARG1239E, ARG1300A, ARG1300E, ARG1391A, ARG1391E, ARG1405A, ARG1405E, ARG1423A, ARG1423E, ARG1428A, ARG1428E, ARG1476A, ARG1476E, ARG1480A, ARG1480E, ARG1495A, ARG1495E, ARG1496A, ARG1496E, ARG1499A, ARG1499E, ASN1256E, ASN1263A, ASN1263E, ASN1410A, ASN1410E, ASP1178A, ASP1178E, ASP1242A, ASP1242E, ASP1248A, ASP1248E, ASP1288A, ASP1288E, ASP1292A, ASP1292E, ASP1387A, ASP1387E, ASP1497A, ASP1497E, ASP1683A, ASP1683E, ASP1689A, ASP1689E, ASP991A, ASP991E, GLN1095A, GLN1296A, GLN1296E, GLN332A, GLN332E, GLN339A, GLN339E, GLU1099A, GLU1099E, GLU1103A, GLU1103E, GLU1107A, GLU1107E, GLU1118A, GLU1118E, GLU1122A, GLU1122E, GLU1217A, GLU1217E, GLU1285A, GLU1285E, GLU1313A, GLU1313E, GLU1317A, GLU1317E, GLU1406A, GLU1406E, GLU1439A, GLU1439E, GLU1469A, GLU1469E, GLU1484A, GLU1484E, GLU1492A, GLU1492E, GLY1271A, GLY1271E, HIS1123A, HIS1123E, HIS1214A, HIS1214E, HIS1473A, HIS1473E, HIS1544A, HIS1544E, ILE1273A, LEU1097A, LEU1097E, LEU1149A, LEU1149E, LEU1697A, LEU1697E, LYS1094A, LYS1152A, LYS1152E, LYS1243A, LYS1243E, LYS1247A, LYS1247E, LYS1274A, LYS1274E, LYS1298A, LYS1298E, LYS1388A, LYS1388E, LYS1630A, LYS1684A, LYS1684E, LYS1694A, LYS1694E, MET1295A, MET1295E, PHE1411E, PHE1627A, PHE336A, PHE336E, PRO1151A, PRO1151E, SER1488A, SER1488E, THR1275A, THR1275E, THR1382A, THR1382E, THR1384E, THR1386A, THR1386E, TYR1240A, TYR1240E, TYR346A, TYR346E, VAL1277A, VAL1277E
• A-F: ARG333A, ARG333F, ARG538A, ARG538F, ARG557A, ARG557F, ARG575A, ARG575F, ARG768A, ARG768F, ARG776A, ARG776F, ARG827A, ARG827F, ASN580F, ASP355A, ASP355F, ASP544A, ASP544F, ASP572A, ASP572F, ASP621A, ASP721A, ASP721F, ASP757A, ASP757F, ASP760A, ASP760F, ASP811A, ASP811F, GLN365F, GLU378A, GLU378F, GLU388A, GLU388F, GLU581F, GLU627A, GLU755A, GLU755F, GLU764A, GLU764F, GLU816A, GLU816F, GLU822A, GLU822F, GLU831A, GLU831F, GLY806A, GLY806F, HIS379A, HIS379F, HIS767A, HIS767F, HIS805A, HIS805F, ILE532A, ILE584F, LYS348A, LYS348F, LYS540A, LYS540F, LYS719A, LYS719F, LYS782A, LYS782F, LYS786A, LYS786F, SER361A, SER830A, SER830F, SER832A, TYR383F, TYR628A
• B-C: ALA353C, ALA357C, ALA360C, ARG1141B, ARG1143B, ARG333B, ARG345C, ARG352C, ASP1105B, ASP1125B, ASP326B, ASP331C, ASP350C, ASP355C, GLN1104B, GLN332B, GLN332C, GLN338C, GLN339B, GLN339C, GLU1103B, GLU1107B, GLU1128B, GLU1131B, GLU341C, GLU363C, GLY1124B, GLY354C, ILE1129B, ILE325B, ILE325C, ILE343B, LEU1106B, LEU328B, LEU328C, LEU335B, LEU335C, LEU351C, LYS1113B, LYS1120B, LYS1126B, LYS1144B, LYS337C, LYS348C, LYS356C, LYS366C, PHE1130B, PHE336B, PHE336C, PHE358C, PRO1108B, THR1139B, THR329B, THR329C, TYR1138B, VAL1127B, VAL359C
• B-D: ALA1111B, ALA1111D, ALA1116B, ALA1116D, ALA1146B, ALA1146D, ALA1153B, ALA1153D, ALA1231B, ALA1231D, ALA1259B, ALA1259D, ALA1260B, ALA1260D, ALA1279B, ALA1279D, ALA1281B, ALA1281D, ALA1299B, ALA1299D, ALA1319B, ALA1319D, ALA1323B, ALA1323D, ALA1385B, ALA1385D, ALA1395B, ALA1395D, ALA1404B, ALA1404D, ALA1465B, ALA1465D, ALA1485B, ALA1485D, ALA1501B, ALA1501D, ALA1632B, ALA1632D, ALA1681B, ALA1681D, ALA1685B, ALA1685D, ARG1093B, ARG1093D, ARG1121B, ARG1121D, ARG1141B, ARG1141D, ARG1233B, ARG1233D, ARG1239B, ARG1239D, ARG1300B, ARG1300D, ARG1391B, ARG1391D, ARG1405B, ARG1405D, ARG1421B, ARG1421D, ARG1423B, ARG1423D, ARG1428B, ARG1428D, ARG1468B, ARG1468D, ARG1470B, ARG1470D, ARG1476B, ARG1476D, ARG1480B, ARG1480D, ARG1495B, ARG1495D, ARG1496B, ARG1496D, ARG1499B, ARG1499D, ARG1702B, ARG1702D, ASN1092B, ASN1092D, ASN1220B, ASN1220D, ASN1256B, ASN1256D, ASN1263B, ASN1263D, ASN1320B, ASN1320D, ASN1410B, ASN1410D, ASN1698B, ASN1698D, ASN989B, ASN989D, ASP1105B, ASP1105D, ASP1178B, ASP1178D, ASP1238B, ASP1238D, ASP1242B, ASP1242D, ASP1248B, ASP1248D, ASP1288B, ASP1288D, ASP1292B, ASP1292D, ASP1308B, ASP1308D, ASP1309D, ASP1387B, ASP1387D, ASP1417B, ASP1417D, ASP1462B, ASP1462D, ASP1497B, ASP1497D, ASP1536B, ASP1536D, ASP1683B, ASP1683D, ASP1689B, ASP1689D, ASP991B, ASP991D, CYS1221B, CYS1221D, CYS1280B, CYS1280D, GLN1095B, GLN1095D, GLN1098B, GLN1098D, GLN1104B, GLN1104D, GLN1115B, GLN1115D, GLN1155B, GLN1155D, GLN1182B, GLN1182D, GLN1246B, GLN1246D, GLN1251B, GLN1251D, GLN1296B, GLN1296D, GLN1311B, GLN1311D, GLN1366B, GLN1366D, GLN1398B, GLN1398D, GLN1424B, GLN1424D, GLN1430B, GLN1430D, GLN1431B, GLN1431D, GLN1434B, GLN1434D, GLN1481B, GLN1481D, GLN1486B, GLN1486D, GLN1540B, GLN1540D, GLN1541B, GLN1541D, GLN1629B, GLN1629D, GLN1633B, GLN1633D, GLN1692B, GLN1692D, GLN1700B, GLN1700D, GLN332B, GLN332D, GLN339B, GLN339D, GLU1099B, GLU1099D, GLU1103B, GLU1103D, GLU1107B, GLU1107D, GLU1110B, GLU1110D, GLU1114B, GLU1114D, GLU1117B, GLU1117D, GLU1118B, GLU1118D, GLU1122B, GLU1122D, GLU1217B, GLU1217D, GLU1252B, GLU1252D, GLU1285B, GLU1285D, GLU1312B, GLU1312D, GLU1313B, GLU1313D, GLU1317B, GLU1317D, GLU1353B, GLU1353D, GLU1406B, GLU1406D, GLU1439B, GLU1439D, GLU1446B, GLU1446D, GLU1463B, GLU1463D, GLU1469B, GLU1469D, GLU1472B, GLU1472D, GLU1477B, GLU1477D, GLU1484B, GLU1484D, GLU1492B, GLU1492D, GLU1688B, GLU1688D, GLY1124B, GLY1124D, GLY1219B, GLY1219D, GLY1223B, GLY1223D, GLY1225B, GLY1225D, GLY1227B, GLY1227D, GLY1228B, GLY1228D, GLY1234B, GLY1234D, GLY1271B, GLY1271D, GLY1278B, GLY1278D, GLY1290B, GLY1290D, GLY1297B, GLY1297D, GLY1314B, GLY1314D, GLY1322B, GLY1322D, GLY1390B, GLY1390D, GLY1397B, GLY1397D, GLY1399B, GLY1399D, GLY1409B, GLY1409D, GLY1490B, GLY1490D, GLY1567B, GLY1567D, GLY1626B, GLY1626D, GLY1628B, GLY1628D, GLY1631B, GLY1631D, HIS1123B, HIS1123D, HIS1214B, HIS1214D, HIS1473B, HIS1473D, HIS1544B, HIS1544D, ILE1102B, ILE1102D, ILE1150B, ILE1150D, ILE1179B, ILE1179D, ILE1180D, ILE1222B, ILE1222D, ILE1249B, ILE1249D, ILE1273B, ILE1273D, ILE1294B, ILE1294D, ILE1389B, ILE1389D, ILE1432B, ILE1432D, ILE1450B, ILE1450D, ILE1474B, ILE1474D, ILE1500B, ILE1500D, LEU1096B, LEU1096D, LEU1097B, LEU1097D, LEU1106B, LEU1106D, LEU1142B, LEU1142D, LEU1148B, LEU1148D, LEU1149B, LEU1149D, LEU1154B, LEU1154D, LEU1215B, LEU1215D, LEU1232B, LEU1232D, LEU1241B, LEU1241D, LEU1250B, LEU1250D, LEU1265B, LEU1265D, LEU1266B, LEU1266D, LEU1267B, LEU1267D, LEU1287B, LEU1287D, LEU1367B, LEU1367D, LEU1401B, LEU1401D, LEU1415B, LEU1415D, LEU1416B, LEU1416D, LEU1427B, LEU1427D, LEU1441B, LEU1441D, LEU1443B, LEU1443D, LEU1467B, LEU1467D, LEU1503B, LEU1503D, LEU1542B, LEU1542D, LEU1545B, LEU1545D, LEU1697B, LEU1697D, LEU990B, LEU990D, LYS1094B, LYS1094D, LYS1120B, LYS1120D, LYS1152B, LYS1152D, LYS1237B, LYS1237D, LYS1243B, LYS1243D, LYS1247B, LYS1247D, LYS1274B, LYS1274D, LYS1298B, LYS1298D, LYS1328B, LYS1328D, LYS1388B, LYS1388D, LYS1407B, LYS1407D, LYS1543B, LYS1543D, LYS1566B, LYS1566D, LYS1630B, LYS1630D, LYS1682B, LYS1682D, LYS1684B, LYS1684D, LYS1694B, LYS1694D, LYS992B, LYS992D, MET1235B, MET1235D, MET1258B, MET1258D, MET1264B, MET1264D, MET1295B, MET1295D, MET1321B, MET1321D, MET1381B, MET1381D, PHE1109B, PHE1109D, PHE1119B, PHE1119D, PHE1156B, PHE1156D, PHE1254B, PHE1254D, PHE1318B, PHE1318D, PHE1351B, PHE1351D, PHE1411B, PHE1411D, PHE1461B, PHE1461D, PHE1489B, PHE1489D, PHE1493B, PHE1493D, PHE1627B, PHE1627D, PHE1679B, PHE1679D, PHE1696B, PHE1696D, PRO1091B, PRO1091D, PRO1108B, PRO1108D, PRO1151B, PRO1151D, PRO1176B, PRO1176D, PRO1206B, PRO1206D, PRO1272B, PRO1272D, PRO1276B, PRO1276D, PRO1394B, PRO1394D, PRO1412B, PRO1412D, PRO1414B, PRO1414D, PRO1460B, PRO1460D, PRO1502B, PRO1502D, PRO1686B, PRO1686D, PRO1699B, PRO1699D, SER1112B, SER1112D, SER1216B, SER1216D, SER1224B, SER1224D, SER1230B, SER1230D, SER1253B, SER1253D, SER1268B, SER1268D, SER1269B, SER1269D, SER1286B, SER1286D, SER1315B, SER1315D, SER1383B, SER1383D, SER1392B, SER1392D, SER1408B, SER1408D, SER1413B, SER1413D, SER1438B, SER1438D, SER1488B, SER1488D, SER1498B, SER1498D, SER1693B, SER1693D, SER1701B, SER1701D, THR1147B, THR1147D, THR1187B, THR1187D, THR1229B, THR1229D, THR1257B, THR1257D, THR1270B, THR1270D, THR1275B, THR1275D, THR1282B, THR1282D, THR1293B, THR1293D, THR1364B, THR1364D, THR1382B, THR1382D, THR1384B, THR1384D, THR1386B, THR1386D, THR1402B, THR1402D, THR1403B, THR1403D, THR1464B, THR1464D, THR1487B, THR1487D, TRP1261B, TRP1261D, TRP1435B, TRP1435D, TRP1494B, TRP1494D, TYR1207B, TYR1207D, TYR1210B, TYR1210D, TYR1236B, TYR1236D, TYR1240B, TYR1240D, TYR1291B, TYR1291D, TYR1316B, TYR1316D, TYR1420B, TYR1420D, TYR1442B, TYR1442D, TYR1466B, TYR1466D, TYR1687B, TYR1687D, TYR346B, TYR346D, VAL1100B, VAL1100D, VAL1101B, VAL1101D, VAL1127B, VAL1127D, VAL1140B, VAL1140D, VAL1183B, VAL1183D, VAL1213B, VAL1213D, VAL1218B, VAL1218D, VAL1226B, VAL1226D, VAL1245B, VAL1245D, VAL1255B, VAL1255D, VAL1262B, VAL1262D, VAL1277B, VAL1277D, VAL1289B, VAL1289D, VAL1301B, VAL1301D, VAL1379B, VAL1379D, VAL1393B, VAL1393D, VAL1400B, VAL1400D, VAL1537B, VAL1537D, VAL1680B, VAL1680D, VAL1695B, VAL1695D, VAL993B, VAL993D, VAL994B, VAL994D
• B-E: ALA334B, ALA334E, ALA344B, ALA344E, ALA353B, ALA353E, ALA357B, ALA357E, ALA360B, ALA360E, ALA367B, ALA367E, ALA370B, ALA370E, ALA377B, ALA377E, ALA384B, ALA384E, ALA385B, ALA385E, ALA568B, ALA568E, ALA576B, ALA576E, ALA578B, ALA578E, ARG333B, ARG333E, ARG345B, ARG345E, ARG352B, ARG352E, ARG538B, ARG538E, ARG546B, ARG546E, ARG553B, ARG553E, ARG554B, ARG554E, ARG557B, ARG557E, ARG575B, ARG575E, ARG618B, ARG618E, ARG768B, ARG768E, ARG776B, ARG776E, ARG827B, ARG827E, ASN537B, ASN537E, ASN543B, ASN543E, ASN567B, ASN567E, ASN580B, ASN625B, ASN625E, ASN715B, ASN715E, ASN773B, ASP331E, ASP350B, ASP350E, ASP355B, ASP355E, ASP373B, ASP373E, ASP381B, ASP381E, ASP544B, ASP544E, ASP572B, ASP572E, ASP621E, ASP721B, ASP721E, ASP757B, ASP757E, ASP760B, ASP760E, ASP811B, ASP811E, GLN1104B, GLN332B, GLN332E, GLN338B, GLN338E, GLN339B, GLN339E, GLN362B, GLN362E, GLN365B, GLN365E, GLN369B, GLN369E, GLN371B, GLN371E, GLN376B, GLN376E, GLN534B, GLN534E, GLN542B, GLN542E, GLN555B, GLN555E, GLN563B, GLN563E, GLN565B, GLN565E, GLN583B, GLN586B, GLN716B, GLN720B, GLN720E, GLN906B, GLU1107B, GLU341B, GLU341E, GLU363B, GLU363E, GLU378B, GLU378E, GLU388B, GLU388E, GLU581B, GLU610B, GLU610E, GLU622E, GLU627B, GLU627E, GLU723E, GLU755B, GLU755E, GLU764B, GLU764E, GLU816B, GLU816E, GLU822B, GLU822E, GLU831B, GLU831E, GLY354B, GLY354E, GLY380B, GLY380E, GLY386B, GLY386E, GLY530E, GLY624E, GLY717B, GLY717E, GLY806B, HIS379B, HIS379E, HIS556B, HIS556E, HIS616E, HIS767B, HIS767E, HIS805B, HIS805E, ILE342B, ILE342E, ILE343B, ILE343E, ILE382B, ILE382E, ILE387B, ILE387E, ILE532B, ILE532E, ILE552B, ILE552E, ILE574B, ILE574E, ILE584B, ILE612B, ILE612E, ILE759B, LEU335B, LEU335E, LEU340B, LEU340E, LEU347B, LEU347E, LEU351B, LEU351E, LEU368B, LEU368E, LEU372B, LEU372E, LEU374B, LEU374E, LEU545B, LEU545E, LEU551B, LEU551E, LEU558B, LEU558E, LEU564E, LEU569B, LEU569E, LEU577B, LEU577E, LEU765B, LYS337B, LYS337E, LYS348B, LYS348E, LYS356B, LYS356E, LYS366B, LYS366E, LYS540B, LYS540E, LYS550B, LYS560B, LYS560E, LYS571E, LYS608B, LYS620E, LYS630E, LYS631E, LYS719B, LYS719E, LYS762B, LYS782B, LYS782E, LYS786B, LYS786E, MET349B, MET349E, MET579B, MET585B, PHE336B, PHE336E, PHE358B, PHE358E, PHE566B, PHE566E, PHE623B, PHE623E, PHE907B, PRO389B, PRO389E, PRO531E, PRO613E, PRO909B, SER361B, SER361E, SER364B, SER364E, SER533B, SER533E, SER536B, SER536E, SER547B, SER547E, SER559B, SER559E, SER561B, SER561E, SER562B, SER562E, SER582B, SER629E, SER718B, SER718E, SER758B, SER761B, SER763B, SER830E, THR329B, THR329E, THR539B, THR539E, THR611E, THR772B, THR807B, THR823B, TRP375B, TRP375E, TRP626B, TRP626E, TYR346B, TYR346E, TYR383B, TYR383E, TYR535B, TYR535E, TYR549B, TYR549E, TYR570B, TYR570E, TYR628E, VAL359B, VAL359E, VAL541B, VAL541E, VAL548B, VAL548E, VAL573B, VAL573E, VAL609E, VAL722B, VAL722E
• B-F: ARG345B, ARG345F, ASP331B, ASP331F, GLN332B, GLN338B, GLN338F, LYS348B, LYS348F, TYR346F
• C-D: ALA334C, ALA334D, ALA344C, ALA344D, ALA353C, ALA353D, ALA357C, ALA357D, ALA360C, ALA360D, ALA367C, ALA367D, ALA370C, ALA370D, ALA377C, ALA377D, ALA384C, ALA384D, ALA385C, ALA385D, ALA568C, ALA568D, ALA576C, ALA576D, ALA578C, ALA578D, ALA780C, ALA780D, ALA820C, ALA820D, ARG333C, ARG333D, ARG345C, ARG345D, ARG352C, ARG352D, ARG538C, ARG538D, ARG546C, ARG546D, ARG553C, ARG553D, ARG557C, ARG557D, ARG575C, ARG575D, ARG618C, ARG618D, ARG754C, ARG754D, ARG768C, ARG768D, ARG776C, ARG776D, ARG827C, ARG827D, ASN537C, ASN537D, ASN543C, ASN543D, ASN567C, ASN567D, ASN580C, ASN625C, ASN625D, ASN715C, ASN715D, ASN773C, ASN773D, ASN804C, ASN804D, ASN810C, ASN810D, ASN826C, ASN826D, ASP331C, ASP331D, ASP350C, ASP350D, ASP355C, ASP355D, ASP373C, ASP373D, ASP381C, ASP381D, ASP544C, ASP544D, ASP572C, ASP572D, ASP621C, ASP621D, ASP721C, ASP721D, ASP757C, ASP757D, ASP760C, ASP760D, ASP811C, ASP811D, ASP910C, ASP910D, GLN1104C, GLN1104D, GLN332C, GLN332D, GLN338C, GLN338D, GLN339C, GLN339D, GLN362C, GLN362D, GLN365C, GLN365D, GLN369C, GLN369D, GLN371C, GLN371D, GLN376C, GLN376D, GLN534C, GLN534D, GLN542C, GLN542D, GLN555C, GLN555D, GLN563C, GLN563D, GLN565C, GLN565D, GLN583C, GLN586C, GLN716C, GLN720C, GLN720D, GLN906C, GLN906D, GLU1107C, GLU1107D, GLU341C, GLU341D, GLU363C, GLU363D, GLU378C, GLU378D, GLU388C, GLU388D, GLU581C, GLU610D, GLU622C, GLU622D, GLU627C, GLU627D, GLU723C, GLU723D, GLU751C, GLU751D, GLU755C, GLU755D, GLU764C, GLU764D, GLU816C, GLU816D, GLU822C, GLU822D, GLU831C, GLU831D, GLY354C, GLY354D, GLY380C, GLY380D, GLY386C, GLY386D, GLY530D, GLY624C, GLY624D, GLY717C, GLY717D, GLY779C, GLY779D, GLY806C, GLY806D, GLY809C, GLY809D, GLY812C, GLY812D, GLY834C, GLY834D, HIS379C, HIS379D, HIS556C, HIS556D, HIS767C, HIS767D, HIS805C, HIS805D, ILE342C, ILE342D, ILE343C, ILE343D, ILE382C, ILE382D, ILE387C, ILE387D, ILE532C, ILE532D, ILE552C, ILE552D, ILE574C, ILE574D, ILE584C, ILE612C, ILE612D, ILE756C, ILE756D, ILE759C, ILE759D, ILE781C, ILE781D, ILE839C, ILE839D, LEU335C, LEU335D, LEU340C, LEU340D, LEU347C, LEU347D, LEU351C, LEU351D, LEU368C, LEU368D, LEU372C, LEU372D, LEU374C, LEU374D, LEU545C, LEU545D, LEU551C, LEU551D, LEU558C, LEU558D, LEU564D, LEU569C, LEU569D, LEU577C, LEU577D, LEU765C, LEU765D, LEU771C, LEU771D, LEU774C, LEU774D, LEU775C, LEU775D, LEU777C, LEU777D, LEU778C, LEU778D, LEU799C, LEU799D, LEU813C, LEU813D, LEU819C, LEU819D, LEU821C, LEU821D, LEU824C, LEU824D, LEU837C, LEU837D, LYS330C, LYS337C, LYS337D, LYS348C, LYS348D, LYS356C, LYS356D, LYS366C, LYS366D, LYS540C, LYS540D, LYS550C, LYS560C, LYS560D, LYS571D, LYS608D, LYS620C, LYS620D, LYS630D, LYS631D, LYS719C, LYS719D, LYS762C, LYS762D, LYS782C, LYS782D, LYS786C, LYS786D, LYS818C, LYS818D, LYS912C, LYS912D, MET349C, MET349D, MET579C, MET579D, MET585C, PHE336C, PHE336D, PHE358C, PHE358D, PHE566C, PHE566D, PHE623C, PHE623D, PHE808C, PHE808D, PHE825C, PHE825D, PHE907C, PHE907D, PRO389C, PRO389D, PRO531D, PRO803C, PRO803D, PRO909C, PRO909D, SER361C, SER361D, SER364C, SER364D, SER533C, SER533D, SER536C, SER536D, SER547C, SER547D, SER559C, SER559D, SER561C, SER561D, SER562C, SER562D, SER582C, SER629D, SER718C, SER718D, SER758C, SER758D, SER761C, SER761D, SER763C, SER763D, SER815C, SER815D, SER817C, SER817D, SER830C, SER830D, SER832C, SER832D, THR329C, THR329D, THR539C, THR539D, THR611D, THR772C, THR772D, THR783C, THR783D, THR807C, THR807D, THR823C, THR823D, TRP375C, TRP375D, TRP626C, TRP626D, TRP828C, TRP828D, TRP833C, TRP833D, TYR346C, TYR346D, TYR383C, TYR383D, TYR535C, TYR535D, TYR549C, TYR549D, TYR570C, TYR570D, TYR628D, TYR814C, TYR814D, TYR829C, TYR829D, TYR836C, TYR836D, VAL359C, VAL359D, VAL541C, VAL541D, VAL548C, VAL548D, VAL573C, VAL573D, VAL609D, VAL722C, VAL722D, VAL797C, VAL797D
• C-E: ALA327C, ALA334C, ALA334E, ALA344C, ALA344E, ARG333C, ARG333E, ARG345C, ARG345E, ASP331C, ASP331E, GLN332C, GLN332E, GLN338C, GLN338E, GLN339C, GLN339E, GLU341C, GLU341E, ILE342C, ILE342E, ILE343C, ILE343E, LEU328C, LEU328E, LEU335C, LEU335E, LEU340C, LEU340E, LEU347C, LEU347E, LYS330C, LYS330E, LYS337C, LYS337E, LYS348C, LYS348E, PHE336C, PHE336E, THR329C, THR329E, TYR346C, TYR346E
• C-F: ALA1153C, ALA1153F, ALA1299C, ALA1299F, ARG1093C, ARG1093F, ARG1121C, ARG1121F, ARG1239C, ARG1239F, ARG1300C, ARG1300F, ARG1391C, ARG1391F, ARG1405C, ARG1405F, ARG1423C, ARG1423F, ARG1428C, ARG1428F, ARG1476C, ARG1476F, ARG1480C, ARG1480F, ARG1495C, ARG1495F, ARG1496C, ARG1496F, ARG1499C, ARG1499F, ASN1256C, ASN1256F, ASN1263C, ASN1263F, ASN1410C, ASN1410F, ASP1178C, ASP1178F, ASP1242C, ASP1242F, ASP1248C, ASP1248F, ASP1288C, ASP1288F, ASP1292C, ASP1292F, ASP1387C, ASP1387F, ASP1497C, ASP1497F, ASP1683C, ASP1683F, ASP1689C, ASP1689F, ASP991C, ASP991F, GLN1095C, GLN1296C, GLN1296F, GLN1540C, GLU1099C, GLU1099F, GLU1103C, GLU1103F, GLU1107C, GLU1107F, GLU1118C, GLU1118F, GLU1122C, GLU1122F, GLU1217C, GLU1217F, GLU1285C, GLU1285F, GLU1313C, GLU1313F, GLU1317C, GLU1317F, GLU1406C, GLU1406F, GLU1439C, GLU1439F, GLU1469C, GLU1469F, GLU1484C, GLU1484F, GLU1492C, GLU1492F, GLY1271C, GLY1271F, HIS1123C, HIS1123F, HIS1214C, HIS1214F, HIS1473C, HIS1473F, HIS1544C, HIS1544F, ILE1273C, LEU1097C, LEU1097F, LEU1149C, LEU1149F, LEU1697C, LEU1697F, LYS1094F, LYS1152C, LYS1152F, LYS1243C, LYS1243F, LYS1247C, LYS1247F, LYS1274C, LYS1274F, LYS1298C, LYS1298F, LYS1388C, LYS1388F, LYS1630C, LYS1684C, LYS1684F, LYS1694C, LYS1694F, MET1295C, MET1295F, PHE1627C, PHE1627F, PRO1151C, PRO1151F, SER1488C, SER1488F, SER1693F, THR1275C, THR1275F, THR1382C, THR1382F, THR1384F, THR1386C, THR1386F, TYR1240C, TYR1240F, VAL1277C, VAL1277F
• D-E: ALA327D, ALA327E, ALA334E, ALA353E, ALA357E, ALA360E, ARG1141D, ARG1143D, ARG333D, ARG345E, ARG352E, ASP1105D, ASP1125D, ASP326D, ASP331E, ASP350E, ASP355E, GLN1104D, GLN332D, GLN332E, GLN338E, GLN339D, GLN339E, GLU1103D, GLU1107D, GLU1128D, GLU1131D, GLU341E, GLY1124D, GLY354E, ILE1129D, ILE325D, ILE325E, ILE343D, LEU1106D, LEU328D, LEU328E, LEU335D, LEU335E, LEU351E, LYS1113D, LYS1120D, LYS1126D, LYS1144D, LYS337E, LYS348E, LYS356E, LYS366E, PHE1130D, PHE336D, PHE336E, PHE358E, PRO1108D, THR1139D, THR329D, THR329E, TYR1138D, VAL1127D, VAL359E
• D-F: ARG1141F, ARG1143F, ARG345D, ARG352D, ASP1105F, ASP350D, ASP355D, GLN332D, GLN332F, GLU1107F, GLU1128F, GLU341D, LYS337D, LYS356D
• E-F: ARG1141E, ARG1143E, ARG345F, ARG352F, ASP1105E, ASP350F, ASP355F, GLN332E, GLN332F, GLU1107E, GLU1128E, GLU341F, LYS337F, LYS356F