2UVA

crystal structure of fatty acid synthase from thermomyces lanuginosus at 3.1 angstrom resolution. this file contains the beta subunits of the fatty acid synthase. the entire crystal structure consists of one heterododecameric fatty acid synthase and is described in remark 400

• Total interactions analyzed: 15
• Total true interactions: 6
• Strongest Interaction:
  • Chains: G-I
  • Int. Res.: 120
  • Norm. En. per Res.: -1.484
• Hub Node: J(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
G-H	-5.9322	-13.6695	-120.583	-140.1847	109	16	0	6209	1	21	25
G-I	-28.1737	-12.5638	-137.345	-178.0825	120	21	0	7287	1	23	29
H-I	-5.3444	-12.6742	-128.338	-146.3566	116	46	1	7110	1	19	27
J-K	-7.6055	-3.5845			12
J-L	-12.094	-14.4147			13
K-L	-16.2893	-19.1252			13

Interface residues

• G-H: ALA1322H, ALA1327H, ALA1334H, ALA1575H, ALA1624H, ALA1625H, ALA325G, ALA332G, ALA437G, ALA46G, ALA46H, ALA94G, ARG1338H, ARG1572H, ARG1582H, ARG213G, ARG22G, ARG22H, ARG328G, ARG376G, ASN1330H, ASN1579H, ASN1627H, ASN1628H, ASN1646H, ASP1323H, ASP1337H, ASP1341H, ASP239G, ASP375G, ASP93G, GLN1319H, GLN220G, GLN229G, GLN323G, GLN324G, GLN337G, GLN44G, GLN47G, GLU1333H, GLU1621H, GLU1626H, GLU374G, GLU92G, GLY1329H, GLY1332H, GLY1339H, GLY1565H, HIS1326H, HIS371G, HIS42G, HIS42H, ILE396G, LEU1563H, LEU1569H, LEU1619H, LEU21H, LEU24H, LEU331G, LEU336G, LEU36H, LEU372G, LEU41G, LEU444G, LYS1340H, LYS219G, LYS223G, LYS49H, PHE1324H, PHE1335H, PHE43G, PRO1150H, PRO1574H, PRO222G, PRO23H, PRO327G, PRO333G, PRO349G, PRO373G, PRO394G, PRO395G, PRO438G, PRO96G, SER1225H, SER1564H, SER1618H, SER322G, SER330G, SER334G, SER397G, SER40G, THR1331H, THR1567H, THR1622H, THR27H, THR329G, THR335G, THR39G, THR39H, THR97G, TRP1623H, TRP215G, TYR326G, TYR443G, VAL1325H, VAL1336H, VAL1583H, VAL218G, VAL25H
• G-I: ALA1322G, ALA1327G, ALA1334G, ALA1575G, ALA1624G, ALA1625G, ALA325I, ALA332I, ALA437I, ALA46G, ALA46I, ALA94I, ARG1338G, ARG1572G, ARG1582G, ARG213I, ARG22G, ARG22I, ARG328I, ARG376I, ASN1330G, ASN1579G, ASN1627G, ASN1628G, ASN1646G, ASN98I, ASP1323G, ASP1337G, ASP1341G, ASP239I, ASP375I, ASP50G, ASP50I, ASP91I, ASP93I, GLN1319G, GLN220I, GLN323I, GLN324I, GLN337I, GLN44I, GLN47I, GLU1333G, GLU1621G, GLU1626G, GLU32G, GLU374I, GLU92I, GLY1329G, GLY1332G, GLY1339G, GLY1565G, HIS1326G, HIS371I, HIS42G, HIS42I, HIS95I, ILE396I, LEU1563G, LEU1569G, LEU1619G, LEU21G, LEU24G, LEU331I, LEU336I, LEU36G, LEU372I, LEU41I, LEU444I, LEU48I, LYS1340G, LYS219I, LYS223I, LYS49G, PHE1324G, PHE1335G, PHE35G, PHE43G, PHE43I, PRO1574G, PRO222I, PRO23G, PRO327I, PRO333I, PRO349I, PRO373I, PRO38I, PRO394I, PRO395I, PRO438I, PRO96I, SER1225G, SER1564G, SER1618G, SER322I, SER330I, SER334I, SER34G, SER397I, SER40I, SER51I, THR1331G, THR1567G, THR1622G, THR27G, THR329I, THR335I, THR39G, THR39I, THR97I, TRP1623G, TRP215I, TYR326I, TYR443I, VAL1325G, VAL1336G, VAL1583G, VAL218I, VAL25G, VAL37G
• H-I: ALA1322I, ALA1327I, ALA1334I, ALA1575I, ALA1624I, ALA1625I, ALA325H, ALA332H, ALA437H, ALA45H, ALA46H, ALA46I, ALA94H, ARG1338I, ARG1572I, ARG1582I, ARG213H, ARG22H, ARG22I, ARG328H, ARG376H, ASN1330I, ASN1579I, ASN1627I, ASN1628I, ASN1646I, ASP1323I, ASP1337I, ASP1341I, ASP239H, ASP375H, ASP50H, ASP93H, GLN1319I, GLN19I, GLN220H, GLN323H, GLN324H, GLN337H, GLN44H, GLN47H, GLU1333I, GLU1621I, GLU1626I, GLU374H, GLU92H, GLY1329I, GLY1332I, GLY1339I, GLY1565I, HIS1326I, HIS371H, HIS42H, HIS42I, HIS95H, ILE396H, LEU1563I, LEU1569I, LEU1619I, LEU21I, LEU24I, LEU331H, LEU336H, LEU36I, LEU372H, LEU41H, LEU444H, LEU48H, LYS1340I, LYS219H, LYS223H, PHE1324I, PHE1335I, PHE35I, PHE43H, PHE43I, PRO1574I, PRO222H, PRO23I, PRO327H, PRO333H, PRO349H, PRO373H, PRO38I, PRO394H, PRO395H, PRO438H, PRO96H, SER1225I, SER1564I, SER1618I, SER20I, SER322H, SER330H, SER334H, SER34I, SER397H, SER40H, SER51H, THR1331I, THR1567I, THR1622I, THR329H, THR335H, THR39H, THR39I, THR97H, TRP1623I, TYR326H, TYR443H, VAL1325I, VAL1336I, VAL1583I, VAL218H, VAL25I, VAL37I
• J-K: ARG1338K, ARG328J, ARG376J, ASP1323K, ASP1337K, ASP375J, GLU1333K, HIS1326K, LYS1340K, LYS219J, SER330J, THR1331K
• J-L: ARG1338J, ARG328L, ARG376L, ASP1323J, ASP1337J, ASP375L, GLU1333J, HIS1326J, LYS1340J, LYS219L, SER330L, THR1331J, THR329L
• K-L: ARG1338L, ARG328K, ARG376K, ASP1323L, ASP1337L, ASP375K, GLU1333L, HIS1326L, LYS1340L, LYS219K, PRO327K, SER330K, THR1331L