2TYS

crystal structures of mutant (betak87t) tryptophan synthase alpha2 beta2 complex with ligands bound to the active sites of the alpha and beta subunits reveal ligand-induced conformational changes

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 119
  • Norm. En. per Res.: -3.4457
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-60.7762	-4.9731	-344.292	-410.0413	119	22	6	13691	2	13	16

Interface residues

• A-B: ALA103A, ALA129A, ALA137A, ALA158A, ALA173B, ALA24B, ALA284B, ALA290B, ALA59A, ALA79A, ARG175B, ARG275B, ASN104A, ASN108A, ASN109A, ASN157A, ASN171B, ASN26B, ASN66A, ASN68A, ASP130A, ASP159A, ASP168B, ASP176B, ASP291B, ASP56A, ASP60A, CYS154A, CYS170B, CYS81A, GLN165A, GLN19B, GLN288B, GLN293B, GLN65A, GLN80A, GLU11B, GLU134A, GLU135A, GLU172B, GLU182B, GLU295B, GLU296B, GLY110A, GLY13B, GLY14B, GLY162B, GLY277B, GLY281B, GLY292B, GLY61A, HIS195B, ILE111A, ILE153A, ILE20B, ILE278B, ILE294B, ILE64A, LEU105A, LEU127A, LEU162A, LEU174B, LEU177A, LEU21B, LEU25B, LEU58A, LEU69A, LYS167B, LYS283B, MET101A, MET15B, MET22B, MET282B, MET286B, MET287B, PHE107A, PHE139A, PHE152A, PHE212A, PHE280B, PHE54A, PHE72A, PRO132A, PRO138A, PRO155A, PRO156A, PRO18B, PRO194B, PRO23B, PRO307B, PRO53A, PRO57A, PRO62A, PRO78A, PRO7B, SER136A, SER161B, SER163B, SER178B, SER55A, THR289B, THR3B, THR77A, TYR102A, TYR169A, TYR16B, TYR181B, TYR279B, TYR8B, VAL106A, VAL128A, VAL131A, VAL133A, VAL159B, VAL166A, VAL17B, VAL276B, VAL52A, VAL76A