2RL7

crystal structure cation-dependent mannose 6-phosphate receptor at ph 4.8

• Total interactions analyzed: 6
• Total true interactions: 4
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 99
  • Norm. En. per Res.: -2.0661
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-16.5428	28.354	-165.941	-154.1299	95	2	4	7358	2	23	21
A-C	-18.8782	-13.3018	-5.6875	-37.8675	25	9	0	1271	0	5	8
A-D	-4.9109	-28.8535	-14.8138	-48.5783	29	3	0	916	3	16	11
C-D	-38.9035	28.662	-194.305	-204.5465	99	8	4	8016	2	26	29

Interface residues

• A-B: ARG112A, ARG112B, ASN120A, ASN120B, ASN127A, ASN127B, ASN129A, ASN129B, ASN90A, ASN90B, ASP140A, ASP140B, ASP148A, ASP148B, CYS106A, CYS106B, CYS119A, CYS119B, CYS141A, CYS141B, GLN110A, GLN139A, GLN139B, GLN84A, GLN84B, GLN87A, GLN87B, GLU109A, GLU109B, GLU133A, GLU133B, GLU134A, GLU134B, GLU146A, GLU146B, GLU19A, GLU19B, GLY10A, GLY10B, GLY88A, GLY88B, HIS105A, HIS105B, ILE117A, ILE117B, ILE85A, ILE85B, ILE92A, ILE92B, ILE95A, ILE95B, LEU144A, LEU144B, LEU22A, LEU22B, LYS18A, LYS97A, LYS97B, MET116A, MET116B, MET147A, MET147B, MET93A, MET93B, PHE142A, PHE142B, PHE145A, PHE145B, PHE86A, PHE86B, PRO130A, SER118A, SER118B, SER132A, SER132B, SER16A, SER16B, SER89A, SER89B, TRP91A, TRP91B, TYR102A, TYR102B, TYR143A, TYR143B, VAL114A, VAL114B, VAL115A, VAL115B, VAL131A, VAL131B, VAL138A, VAL138B, VAL9A, VAL9B
• A-C: ARG121C, ARG25C, ARG50A, ARG53A, ASN120C, ASN90C, CB6.67548-17.67708, CB8.60729-10.42976, CB9.429654.29011, CYS119C, CYS153C, CYS52A, GLN31A, GLU3A, GLU3A5, GLU54A, HIS122C, LYS4A, PHE30A, PHE80A, SER118C, SER154C, SER60A, SER89C, THR5A
• A-D: ALA125D, ALA21A, ARG121D, ASN120D, ASN127D, ASN129D, ASN90D, ASP126D, ASP148D, ASP7A, CYS119D, CYS153D, CYS6A, GLU15A, GLU17A, GLU3A, HIS122D, LEU124D, LEU20A, LEU8A, LYS24A, LYS4A, PHE128D, SER118D, SER16A, SER89D, THR123D, THR27A, THR5A
• C-D: ARG112C, ARG112D, ARG135C, ASN120C, ASN120D, ASN127C, ASN127D, ASN129C, ASN129D, ASN90C, ASN90D, ASP140C, ASP140D, ASP148C, ASP148D, CYS106C, CYS106D, CYS119C, CYS119D, CYS141C, CYS141D, GLN139C, GLN139D, GLN84C, GLN84D, GLN87C, GLN87D, GLU109C, GLU109D, GLU11D, GLU133C, GLU133D, GLU134C, GLU134D, GLU146C, GLU146D, GLU19C, GLU19D, GLY10C, GLY10D, GLY88C, GLY88D, HIS105C, HIS105D, ILE117C, ILE117D, ILE85C, ILE85D, ILE92C, ILE92D, ILE95C, ILE95D, LEU144C, LEU144D, LEU22C, LEU22D, LYS137C, LYS14D, LYS18C, LYS18D, LYS97C, LYS97D, MET116C, MET116D, MET147C, MET147D, MET93C, MET93D, PHE142C, PHE142D, PHE145C, PHE145D, PHE86C, PHE86D, PRO130C, PRO130D, SER118C, SER118D, SER132C, SER132D, SER16D, SER89C, SER89D, TRP91C, TRP91D, TYR102C, TYR102D, TYR143C, TYR143D, VAL114C, VAL114D, VAL115C, VAL115D, VAL131C, VAL131D, VAL138C, VAL138D, VAL9C, VAL9D