2RIO

structure of the dual enzyme ire1 reveals the basis for catalysis and regulation of non-conventional splicing

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 212
  • Norm. En. per Res.: -3.9008
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-123.894	-242.552	-460.527	-826.9729	212	31	4	17788	24	95	83

Interface residues

• A-B: ALA125A, ALA125B, ALA129A, ALA129B, ALA156A, ALA156B, ALA290A, ALA290B, ALA389A, ALA389B, ALA87A, ALA87B, ARG122A, ARG122B, ARG153A, ARG153B, ARG166A, ARG166B, ARG295A, ARG295B, ARG315A, ARG315B, ARG360A, ARG360B, ARG372A, ARG372B, ARG375A, ARG375B, ARG40A, ARG40B, ARG429A, ARG429B, ARG73A, ARG73B, ASN15A, ASN15B, ASN70A, ASN70B, ASP157A, ASP157B, ASP314A, ASP314B, ASP383A, ASP383B, ASP397A, ASP397B, ASP425A, ASP425B, ASP66A, ASP66B, ASP67A, ASP67B, CYS76A, CYS76B, GLN123A, GLN123B, GLN158A, GLN158B, GLN159A, GLN159B, GLN38A, GLN38B, GLN426A, GLN426B, GLU307A, GLU307B, GLU317A, GLU317B, GLU319A, GLU319B, GLU390A, GLU430A, GLU430B, GLU64A, GLU64B, GLU78A, GLU78B, GLU89A, GLU89B, GLY127A, GLY127B, GLY161A, GLY161B, GLY393A, GLY393B, GLY398A, GLY398B, GLY39A, GLY39B, HIS130A, HIS130B, HIS132A, HIS132B, HIS379A, HIS379B, HIS380A, HIS380B, HIS68A, HIS68B, ILE136A, ILE318A, ILE318B, ILE427A, ILE427B, ILE59A, ILE59B, ILE72A, ILE72B, LEU131A, LEU131B, LEU134A, LEU134B, LEU168A, LEU168B, LEU16A, LEU16B, LEU294A, LEU294B, LEU306A, LEU306B, LEU310A, LEU310B, LEU316A, LEU316B, LEU327A, LEU327B, LEU422A, LEU422B, LEU428A, LEU428B, LEU56B, LEU61A, LEU61B, LEU62A, LEU62B, LEU88A, LEU88B, LYS135A, LYS135B, LYS14A, LYS14B, LYS177A, LYS177B, LYS304A, LYS304B, LYS311A, LYS311B, LYS60A, LYS60B, MET291A, MET291B, MET382A, MET382B, PHE154A, PHE154B, PHE308A, PHE37A, PHE37B, PHE381A, PHE381B, PHE399A, PHE399B, PHE431A, PHE431B, PRO301A, PRO301B, PRO394A, PRO394B, PRO396A, PRO396B, PRO41A, PRO41B, PRO69A, PRO69B, SER126A, SER126B, SER133A, SER133B, SER151A, SER151B, SER152A, SER152B, SER303A, SER303B, SER434A, SER434B, SER65A, SER65B, SER77A, SER77B, THR155A, THR155B, THR160A, THR160B, THR63A, THR63B, THR79A, THR79B, TYR378A, TYR378B, TYR74A, TYR74B, TYR75A, TYR75B, TYR85A, TYR85B, VAL128A, VAL128B, VAL395A, VAL395B, VAL71A, VAL71B