2RHK

crystal structure of influenza a ns1a protein in complex with f2f3 fragment of human cellular factor cpsf30, northeast structural genomics targets or8c and hr6309a

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 59
  • Norm. En. per Res.: -6.2067
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-5.7389	-8.5812	-27.1973	-41.5174	31	3	0	1523	2	8	16
A-C	-48.7109	-97.4723	-220.015	-366.1981	59	7	0	7045	8	16	7
A-D	-2.6573	-17.2835	-55.5517	-75.4925	41	3	2	2952	0	14	8
B-C	-3.3247	-10.0226	-58.7762	-72.1236	43	1	2	2962	0	14	8
B-D	-46.8472	-95.1529	-221.036	-363.0361	60	8	0	7155	7	16	8
C-D	-46.6548	22.766	-73.4729	-97.3617	19	6	0	2448	0	4	6

Interface residues

• A-B: ALA122A, ALA122B, ASN188A, ASN188B, ASN190A, ASP120A, ASP120B, ASP125A, ASP125B, ASP189A, ASP189B, GLN121A, GLN121B, GLU153A, GLU153B, ILE123A, ILE123B, LEU105A, LEU105B, LYS126A, LYS126B, MET106A, MET106B, MET124A, MET124B, PHE103A, PHE103B, THR151A, THR151B, TRP187A, TRP187B
• A-C: ALA122A, ALA177A, ARG118A, ARG73C, ASN107C, ASN188A, ASN190A, ASP120A, ASP125A, ASP189A, CYS105C, CYS110C, CYS116A, CYS96C, GLN109A, GLN121A, GLU104C, GLU112A, GLU159A, GLU186A, GLU95C, GLY103C, GLY179A, GLY183A, GLY184A, HIS114C, HIS70C, ILE117A, ILE119A, ILE123A, ILE178A, ILE182A, LEU105A, LEU113C, LEU181A, LEU185A, LEU75C, LYS101C, LYS108A, LYS110A, LYS126A, LYS69C, MET104A, MET106A, MET124A, MET93C, PHE102C, PHE112C, PHE98C, PRO107A, PRO111C, SER100C, SER106C, SER94C, TRP187A, TYR97C, TYR99C, VAL111A, VAL180A
• A-D: ALA122A, ALA155A, ARG100A, ARG73D, ASN107D, ASP101A, ASP120A, CYS105D, CYS110D, GLN121A, GLU109D, GLU153A, GLY154A, GLY74D, ILE123A, ILE156A, LEU105A, LEU72D, LEU75D, LYS108A, LYS108D, LYS126A, LYS69D, LYS77D, MET104A, MET106A, MET124A, MET90D, MET93D, PHE103A, PHE112D, PHE98D, PRO107A, PRO111D, SER106D, THR151A, TRP102A, TRP71D, TYR88D, VAL157A, VAL67D
• B-C: ALA122B, ALA155B, ARG100B, ARG73C, ASN107C, ASP101B, ASP120B, CYS105C, CYS110C, CYS96C, GLN121B, GLU109C, GLU153B, GLU87C, GLY154B, GLY74C, ILE123B, ILE156B, LEU105B, LEU72C, LEU75C, LYS108B, LYS108C, LYS126B, LYS69C, LYS77C, MET104B, MET106B, MET124B, MET90C, MET93C, PHE103B, PHE112C, PHE98C, PRO107B, PRO111C, SER106C, THR151B, TRP102B, TRP71C, TYR88C, VAL157B, VAL67C
• B-D: ALA122B, ALA177B, ARG118B, ARG73D, ASN107D, ASN176B, ASN188B, ASN190B, ASP120B, ASP125B, ASP189B, CYS105D, CYS110D, CYS116B, CYS96D, GLN109B, GLN121B, GLU104D, GLU109D, GLU112B, GLU186B, GLU95D, GLY103D, GLY179B, GLY183B, GLY184B, HIS114D, HIS70D, ILE117B, ILE119B, ILE123B, ILE178B, ILE182B, LEU105B, LEU113D, LEU181B, LEU185B, LEU75D, LYS101D, LYS108B, LYS108D, LYS110B, LYS126B, LYS69D, MET106B, MET124B, MET93D, PHE102D, PHE112D, PHE98D, PRO107B, PRO111D, SER100D, SER106D, SER94D, TRP187B, TYR97D, TYR99D, VAL111B, VAL180B
• C-D: ASN107C, ASN107D, CYS105C, CYS105D, CYS110C, CYS110D, CYS96D, GLU104C, GLU104D, GLU109C, GLU109D, HIS114C, HIS114D, LYS108C, LYS108D, SER106C, SER106D, TYR99C, TYR99D