2RFN

x-ray structure of c-met with inhibitor.

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 91
  • Norm. En. per Res.: -3.3298
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-26.0269	-71.4874	-205.502	-303.0163	91	4	9	9523	11	28	25

Interface residues

• A-B: ALA1057A, ALA1057B, ALA1065A, ALA1065B, ARG1114A, ARG1114B, ARG1203A, ARG1203B, ASN1059A, ASN1059B, ASP1117A, ASP1117B, ASP1133A, ASP1133B, GLN1064A, GLN1064B, GLN1067A, GLN1067B, GLN1123A, GLN1123B, GLN1258A, GLN1258B, GLU1061A, GLU1061B, GLU1120A, GLU1120B, GLU1127A, GLU1127B, GLY1119A, GLY1119B, GLY1128A, HIS1068A, HIS1068B, HIS1202A, ILE1115B, ILE1118A, ILE1118B, ILE1129A, ILE1129B, ILE1130A, ILE1130B, LEU1058A, LEU1058B, LEU1062A, LEU1062B, LEU1125A, LEU1125B, LEU1195A, LEU1195B, LYS1132A, LYS1132B, LYS1198A, LYS1198B, LYS1199A, LYS1199B, LYS1259A, LYS1259B, MET1131A, MET1131B, PHE1124A, PHE1124B, PHE1134A, PHE1134B, PHE1200A, PHE1200B, PHE1260A, PHE1260B, PRO1060A, PRO1060B, SER1122A, SER1122B, SER1197A, SER1197B, THR1116A, THR1116B, THR1126A, THR1126B, THR1261A, THR1261B, THR1262A, THR1262B, VAL1063A, VAL1063B, VAL1066A, VAL1066B, VAL1069A, VAL1069B, VAL1121A, VAL1121B, VAL1201A, VAL1201B