2RF4

crystal structure of the rna polymerase i subcomplex a14/43

• Total interactions analyzed: 15
• Total true interactions: 11
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 136
  • Norm. En. per Res.: -4.1112
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-72.1647	-59.303	-409.043	-540.5107	134	37	18	17963	4	22	23
A-C	0.0	13.8329	-0.4555	13.3774	6	0	0	34	0	2	1
A-D	-6.0783	-39.5737	-75.6199	-121.272	59	1	0	3892	3	16	11
A-E	0.0	0.0	-4.0243	-4.0243	14	0	0	330	0	4	2
B-C	-6.6137	-51.5323	-80.3075	-138.4534	56	2	1	3994	5	17	11
B-D	0.0	34.0841	-16.4315	17.6526	14	4	0	534	0	2	5
B-E	0.0	-16.0173	-30.5421	-46.5594	34	1	0	2281	0	13	5
C-D	-80.8199	-57.3136	-420.995	-559.1285	136	36	18	17865	4	23	26
C-E	0.0	0.0	-1.9032	-1.9032	24	0	0	373	0	3	5
D-E	0.0	0.0	-10.4992	-10.4992	9	0	0	500	0	0	0
E-F	-74.0969	-56.0933	-405.513	-535.7032	134	40	18	17624	4	22	24

Interface residues

• A-B: ALA152A, ALA24B, ALA44A, ARG241A, ARG40A, ARG91B, ARG94B, ASN121A, ASN154A, ASN17B, ASN26A, ASN32A, ASN36A, ASN67A, ASN74A, ASN75A, ASN81B, ASP131A, ASP151A, ASP29A, ASP52B, ASP79B, ASP91A, ASP95B, CYS118A, CYS37A, GLN126A, GLN128A, GLN23A, GLN26B, GLN29B, GLN38B, GLN59A, GLN64A, GLN88B, GLN93B, GLU134A, GLU30A, GLU35B, GLU46B, GLU85A, GLY114A, GLY135A, GLY83A, GLY86A, GLY98B, HIS119A, HIS150A, HIS23B, HIS30B, HIS65A, ILE149A, ILE22B, ILE38A, ILE43A, ILE44B, ILE51B, ILE78B, ILE86B, ILE92B, LEU122A, LEU148A, LEU16B, LEU27B, LEU37B, LEU40B, LEU45A, LEU49A, LEU58A, LEU66A, LEU69A, LEU82A, LEU82B, LEU87A, LEU89B, LEU99B, LYS228A, LYS31A, LYS47B, LYS63A, LYS72A, LYS76A, LYS90B, PHE115A, PHE138A, PHE153A, PHE39B, PHE43B, PHE96B, PRO100B, PRO101B, PRO127A, PRO19B, PRO27A, PRO28B, PRO42A, PRO68A, SER32B, SER35A, SER42B, SER48A, SER83B, SER84B, SER85B, SER87B, THR116A, THR18B, THR25A, THR25B, THR33B, THR34A, THR80B, TRP117A, TRP125A, TYR123A, TYR136A, TYR46A, TYR84A, VAL120A, VAL124A, VAL20B, VAL21B, VAL242A, VAL24A, VAL31B, VAL36B, VAL39A, VAL41A, VAL47A, VAL61A, VAL70A, VAL77A, VAL80A, VAL81A
• A-C: ASP151A, ASP151C, LEU148A, LEU148C, PHE138A, PHE138C
• A-D: ALA152A, ARG241A, ARG91D, ARG94D, ASN154A, ASN171A, ASN211A, ASN81D, ASP151A, ASP172A, ASP34D, ASP79D, ASP95D, GLN140A, GLN38D, GLN88D, GLN93D, GLU41D, GLU48D, GLY146A, GLY210A, GLY215A, GLY227A, GLY98D, HIS144A, HIS150A, HIS216A, ILE137A, ILE139A, ILE149A, ILE44D, ILE86D, ILE92D, LEU147A, LEU148A, LEU214A, LEU37D, LEU40D, LEU82D, LEU89D, LEU99D, LYS90D, LYS97D, PHE138A, PHE153A, PHE168A, PHE39D, PHE96D, PRO101D, SER141A, SER213A, SER42D, SER83D, SER84D, SER87D, THR33D, THR80D, TYR136A, VAL242A
• A-E: ARG241E, ASN235E, ASN56A, ASN75E, GLN59A, GLU55A, GLY240E, HIS237E, LEU54A, LYS63A, THR238E, THR239E, TYR53A, VAL236E
• B-C: ALA152C, ARG241C, ARG91B, ARG94B, ASN154C, ASN171C, ASN81B, ASP151C, ASP34B, ASP79B, ASP95B, GLN140C, GLN38B, GLN88B, GLN93B, GLU41B, GLU48B, GLY146C, GLY210C, GLY215C, GLY227C, GLY98B, HIS144C, HIS150C, HIS216C, ILE137C, ILE139C, ILE149C, ILE44B, ILE86B, ILE92B, LEU147C, LEU148C, LEU214C, LEU37B, LEU82B, LEU89B, LEU99B, LYS90B, LYS97B, PHE138C, PHE153C, PHE168C, PHE39B, PHE96B, PRO101B, SER141C, SER213C, SER42B, SER83B, SER84B, SER87B, THR33B, THR80B, TYR136C, VAL242C
• B-D: ARG91B, ARG91D, ARG94B, ARG94D, ASN81B, ASN81D, GLN88B, GLN88D, ILE92B, ILE92D, SER84B, SER84D, SER87B, SER87D
• B-E: ARG234E, ASN235E, ASN26E, ASN49B, ASN74E, ASN75E, ASN81B, ASP131E, ASP45B, ASP52B, ASP79B, GLN126E, GLN128E, GLN23E, GLU46B, GLU48B, GLY130E, GLY78E, GLY79E, ILE50B, ILE51B, ILE78B, LYS21E, LYS22E, LYS76E, PRO127E, THR238E, THR25E, THR80B, TYR73E, VAL129E, VAL236E, VAL24E, VAL77E
• C-D: ALA152C, ALA24D, ALA44C, ALA50C, ARG40C, ARG91D, ARG94D, ASN121C, ASN154C, ASN17D, ASN26C, ASN32C, ASN36C, ASN67C, ASN74C, ASN75C, ASN81D, ASP131C, ASP151C, ASP29C, ASP52D, ASP79D, ASP91C, ASP95D, CYS118C, CYS37C, GLN126C, GLN128C, GLN23C, GLN26D, GLN29D, GLN38D, GLN59C, GLN64C, GLN88D, GLN93D, GLU134C, GLU30C, GLU35D, GLU46D, GLU85C, GLY114C, GLY135C, GLY83C, GLY86C, GLY98D, HIS119C, HIS150C, HIS23D, HIS30D, HIS65C, ILE149C, ILE22D, ILE38C, ILE43C, ILE44D, ILE51D, ILE78D, ILE86D, ILE92D, LEU122C, LEU148C, LEU27D, LEU37D, LEU40D, LEU45C, LEU49C, LEU58C, LEU66C, LEU69C, LEU82C, LEU82D, LEU87C, LEU89D, LEU99D, LYS228C, LYS22C, LYS31C, LYS47D, LYS63C, LYS72C, LYS76C, LYS90D, PHE115C, PHE138C, PHE153C, PHE39D, PHE43D, PHE96D, PRO100D, PRO101D, PRO127C, PRO19D, PRO27C, PRO28D, PRO42C, PRO51C, PRO68C, SER32D, SER35C, SER42D, SER48C, SER83D, SER84D, SER85D, SER87D, THR116C, THR18D, THR25C, THR25D, THR33D, THR34C, THR80D, TRP117C, TRP125C, TYR123C, TYR136C, TYR46C, TYR53C, TYR84C, VAL120C, VAL124C, VAL20D, VAL21D, VAL242C, VAL24C, VAL31D, VAL36D, VAL39C, VAL41C, VAL47C, VAL61C, VAL70C, VAL77C, VAL80C, VAL81C
• C-E: ALA142C, ARG234E, ARG241C, ASP131E, ASP165E, GLY130E, GLY240C, HIS144C, HIS237C, ILE250E, ILE28E, LYS158C, LYS22E, SER141C, SER143C, SER48C, THR232E, THR238C, THR239C, THR248E, THR25E, VAL129E, VAL132E, VAL233E
• D-E: ASN17D, ASN221E, ASP165E, PRO163E, PRO19D, SER220E, THR18D, TRP166E, VAL164E
• E-F: ALA152E, ALA24F, ALA44E, ALA50E, ARG40E, ARG91F, ARG94F, ASN121E, ASN154E, ASN26E, ASN32E, ASN36E, ASN67E, ASN74E, ASN75E, ASN81F, ASP131E, ASP151E, ASP29E, ASP52F, ASP79F, ASP91E, ASP95F, CYS118E, CYS37E, GLN126E, GLN128E, GLN23E, GLN26F, GLN29F, GLN38F, GLN59E, GLN64E, GLN88F, GLN93F, GLU134E, GLU30E, GLU35F, GLU46F, GLU85E, GLY135E, GLY83E, GLY86E, GLY98F, HIS119E, HIS150E, HIS23F, HIS30F, HIS65E, ILE149E, ILE22F, ILE38E, ILE43E, ILE44F, ILE51F, ILE78F, ILE86F, ILE92F, LEU122E, LEU148E, LEU27F, LEU37F, LEU40F, LEU45E, LEU49E, LEU58E, LEU66E, LEU69E, LEU82E, LEU82F, LEU87E, LEU89F, LEU99F, LYS21E, LYS228E, LYS22E, LYS31E, LYS47F, LYS63E, LYS72E, LYS76E, LYS90F, PHE115E, PHE138E, PHE153E, PHE39F, PHE43F, PHE96F, PRO100F, PRO101F, PRO127E, PRO19F, PRO27E, PRO28F, PRO42E, PRO68E, SER32F, SER35E, SER42F, SER48E, SER83F, SER84F, SER85F, SER87F, THR116E, THR18F, THR25E, THR25F, THR33F, THR34E, THR80F, TRP117E, TRP125E, TYR123E, TYR136E, TYR46E, TYR53E, TYR84E, VAL120E, VAL124E, VAL20F, VAL21F, VAL242E, VAL24E, VAL31F, VAL36F, VAL39E, VAL41E, VAL47E, VAL61E, VAL70E, VAL77E, VAL80E, VAL81E