2RAX

crystal structure of borealin (20-78) bound to survivin (1-120)

• Total interactions analyzed: 15
• Total true interactions: 9
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 77
  • Norm. En. per Res.: -4.3829
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-44.9622	-20.2313	-264.745	-329.9385	76	8	9	10729	3	24	23
A-E	0.0	0.0	-9.8191	-9.8191	11	0	0	405	0	0	4
A-F	0.0	1.8586	-67.0158	-65.1572	47	5	2	3606	2	21	20
A-X	0.0	0.0	-0.3349	-0.3349	8	0	0	105	0	7	2
B-E	-7.709	-7.9917	-72.8533	-88.554	46	4	3	3801	2	21	21
B-F	-20.3386	-58.821	-222.609	-301.7686	97	13	5	9494	6	28	34
B-X	-10.4283	2.1393	-8.6665	-16.9555	19	1	0	562	0	11	11
E-F	-47.053	-11.1429	-279.285	-337.4809	77	7	9	10940	2	23	23
X-Y	-47.3472	-16.9406	-251.091	-315.3788	77	8	8	10174	2	22	22

Interface residues

• A-B: ALA109A, ALA114A, ALA64B, ARG106A, ARG108A, ARG18A, ARG43B, ARG60B, ARG66B, ASN111A, ASN118A, ASN119A, ASN45B, ASN52B, ASN55B, ASN69B, ASP105A, ASP42B, ASP51B, ASP72B, GLN11A, GLN44B, GLN92A, GLU100A, GLU107A, GLU116A, GLU40B, GLU49B, GLU57B, GLU67B, GLU94A, GLU95A, GLY99A, ILE113A, ILE39B, ILE56B, ILE58B, LEU102A, LEU104A, LEU14A, LEU46B, LEU47B, LEU53B, LEU59B, LEU61B, LEU65B, LEU6A, LEU71B, LEU76B, LEU96A, LEU98A, LYS103A, LYS110A, LYS112A, LYS115A, LYS15A, LYS48B, LYS63B, LYS91A, MET68B, PHE101A, PHE13A, PHE58A, PHE74B, PHE93A, PRO12A, PRO62B, PRO7A, THR117A, THR5A, THR97A, TRP10A, TRP70B, TYR54B, TYR73B, VAL50B
• A-E: ALA114A, ALA114E, ASN118A, ASN118E, ASN119A, ASN119E, GLU116A, ILE113A, ILE113E, THR117A, THR117E
• A-F: ALA109A, ALA114A, ALA22F, ALA9A, ARG106A, ARG108A, ARG30F, ARG35F, ARG43F, ASN111A, ASN118A, ASN119A, ASP105A, ASP29F, ASP42F, GLN44F, GLU116A, GLU31F, GLU33F, GLU40F, ILE113A, ILE34F, ILE36F, ILE39F, LEU102A, LEU25F, LEU47F, LEU98A, LYS110A, LYS112A, LYS115A, LYS20F, LYS26F, LYS37F, MET19F, PHE101A, PHE24F, PHE28F, PHE61A, PRO7A, PRO8A, SER23F, SER41F, THR117A, THR5A, TRP10A, VAL32F
• A-X: ALA32X, ARG106A, ARG37X, CYS31X, GLU29X, GLY30X, LYS103A, THR34X
• B-E: ALA109E, ALA114E, ALA22B, ALA9E, ARG106E, ARG108E, ARG30B, ARG35B, ARG43B, ASN118E, ASN119E, ASP105E, ASP29B, ASP42B, GLN44B, GLU116E, GLU31B, GLU33B, GLU40B, ILE113E, ILE34B, ILE36B, ILE39B, LEU102E, LEU21B, LEU25B, LEU47B, LEU6E, LEU98E, LYS110E, LYS112E, LYS115E, LYS20B, LYS26B, LYS37B, PHE101E, PHE24B, PHE28B, PHE61E, PRO7E, PRO8E, SER23B, SER41B, THR117E, TRP10E, VAL32B
• B-F: ALA22B, ALA22F, ALA75B, ALA75F, ARG35B, ARG35F, ARG43B, ARG43F, ARG60B, ARG60F, ASN45B, ASN45F, ASN52B, ASN52F, ASP27B, ASP27F, ASP29B, ASP29F, ASP42B, ASP42F, ASP51B, ASP51F, ASP72B, ASP72F, GLN38B, GLN38F, GLN44B, GLN44F, GLU31B, GLU31F, GLU33B, GLU33F, GLU40B, GLU40F, GLU49B, GLU49F, GLU57B, GLU57F, ILE34B, ILE34F, ILE36B, ILE36F, ILE39B, ILE39F, ILE56B, ILE56F, ILE58B, ILE58F, LEU21B, LEU21F, LEU25B, LEU25F, LEU46B, LEU46F, LEU47B, LEU47F, LEU53B, LEU53F, LEU61B, LEU61F, LEU65B, LEU65F, LEU71B, LEU71F, LEU76B, LEU76F, LYS20B, LYS20F, LYS26F, LYS37B, LYS37F, LYS48B, LYS48F, MET19B, MET19F, MET68B, MET68F, PHE24B, PHE24F, PHE28B, PHE28F, PHE74B, PHE74F, SER23B, SER23F, SER41B, SER41F, TRP70B, TRP70F, TYR54B, TYR54F, TYR73B, TYR73F, VAL32B, VAL32F, VAL50B, VAL50F
• B-X: ARG37X, ARG66B, ASN55B, ASP51B, GLN92X, GLU29X, GLU36X, GLU40X, GLU95X, ILE19X, LEU59B, LYS15X, LYS63B, LYS90X, LYS91X, PHE93X, PRO62B, THR34X, VAL89X
• E-F: ALA109E, ALA114E, ALA64F, ALA9E, ARG106E, ARG108E, ARG18E, ARG43F, ARG60F, ARG66F, ASN111E, ASN118E, ASN119E, ASN45F, ASN52F, ASN55F, ASN69F, ASP105E, ASP42F, ASP51F, ASP72F, GLN11E, GLN44F, GLN92E, GLU100E, GLU107E, GLU116E, GLU40F, GLU49F, GLU57F, GLU67F, GLU94E, GLU95E, GLY99E, ILE113E, ILE39F, ILE56F, ILE58F, LEU102E, LEU104E, LEU14E, LEU46F, LEU47F, LEU53F, LEU59F, LEU61F, LEU65F, LEU6E, LEU71F, LEU76F, LEU96E, LEU98E, LYS103E, LYS110E, LYS112E, LYS115E, LYS15E, LYS48F, LYS63F, LYS91E, MET68F, PHE101E, PHE13E, PHE58E, PHE74F, PHE93E, PRO12E, PRO62F, PRO7E, THR117E, THR5E, THR97E, TRP10E, TRP70F, TYR54F, TYR73F, VAL50F
• X-Y: ALA109X, ALA114X, ALA64Y, ALA75Y, ARG106X, ARG108X, ARG18X, ARG43Y, ARG60Y, ARG66Y, ASN111X, ASN118X, ASN45Y, ASN52Y, ASN55Y, ASN69Y, ASP105X, ASP16X, ASP42Y, ASP51Y, ASP72Y, GLN11X, GLN44Y, GLN92X, GLU100X, GLU107X, GLU116X, GLU40Y, GLU49Y, GLU57Y, GLU67Y, GLU94X, GLU95X, GLY99X, ILE113X, ILE39Y, ILE56Y, ILE58Y, LEU102X, LEU104X, LEU14X, LEU46Y, LEU47Y, LEU53Y, LEU59Y, LEU61Y, LEU65Y, LEU6X, LEU71Y, LEU76Y, LEU96X, LEU98X, LYS103X, LYS110X, LYS112X, LYS115X, LYS15X, LYS48Y, LYS63Y, LYS91X, MET68Y, PHE101X, PHE13X, PHE58X, PHE74Y, PHE93X, PRO12X, PRO62Y, PRO7X, THR117X, THR5X, THR97X, TRP10X, TRP70Y, TYR54Y, TYR73Y, VAL50Y