2R7E

crystal structure analysis of coagulation factor viii

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 298
  • Norm. En. per Res.: -2.81
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-43.4785	-33.2639	-760.628	-837.3704	298	108	11	35386	3	101	99

Interface residues

• A-B: ALA100A, ALA108A, ALA112A, ALA148A, ALA1800B, ALA1824B, ALA1834B, ALA1836B, ALA1974B, ALA1993B, ALA2008B, ALA2077B, ALA2328B, ARG121A, ARG1797B, ARG1803B, ARG1917B, ARG1966B, ARG1997B, ARG279A, ARG4A, ARG698A, ARG700A, ASN144A, ASN169A, ASN1805B, ASN1950B, ASN1952B, ASN1977B, ASN2172B, ASN280A, ASN684A, ASN694A, ASN699A, ASP115A, ASP116A, ASP125A, ASP150A, ASP163A, ASP167A, ASP1795B, ASP1828B, ASP1831B, ASP1840B, ASP1842B, ASP1927B, ASP2170B, ASP2298B, ASP2330B, ASP525A, ASP647A, ASP666A, ASP696A, ASP712A, CYS1832B, CYS2000B, CYS2174B, CYS711A, GLN117A, GLN120A, GLN139A, GLN1796B, GLN1798B, GLN1820B, GLN1936B, GLN2266B, GLN2276B, GLN2329B, GLN645A, GLU110A, GLU113A, GLU122A, GLU124A, GLU143A, GLU1793B, GLU1794B, GLU1801B, GLU1829B, GLU1844B, GLU1951B, GLU1969B, GLU1970B, GLU1984B, GLU1987B, GLU1999B, GLU2004B, GLU2327B, GLU265A, GLU287A, GLU665A, GLU683A, GLY102A, GLY111A, GLY145A, GLY1799B, GLY1948B, GLY1960B, GLY1981B, GLY1994B, GLY2003B, GLY259A, GLY261A, GLY655A, GLY686A, GLY691A, HIS161A, HIS1821B, HIS1822B, HIS1859B, HIS1954B, HIS1957B, HIS1961B, HIS2005B, HIS2007B, HIS281A, HIS632A, HIS660A, HIS693A, HIS99A, ILE173A, ILE1790B, ILE1882B, ILE1953B, ILE1956B, ILE1995B, ILE2002B, ILE258A, ILE288A, ILE291A, ILE689A, ILE86A, LEU141A, LEU154A, LEU159A, LEU164A, LEU168A, LEU1789B, LEU1843B, LEU1945B, LEU1975B, LEU1989B, LEU2001B, LEU2006B, LEU2013B, LEU2015B, LEU2171B, LEU2301B, LEU2302B, LEU2331B, LEU294A, LEU631A, LEU649A, LEU668A, LEU670A, LEU687A, LEU690A, LEU705A, LYS107A, LYS123A, LYS142A, LYS166A, LYS1804B, LYS1818B, LYS1827B, LYS1833B, LYS1845B, LYS1887B, LYS1967B, LYS1968B, LYS1972B, LYS1992B, LYS206A, LYS2239B, LYS523A, LYS659A, LYS661A, LYS707A, MET147A, MET1823B, MET1947B, MET1973B, MET1988B, MET260A, MET662A, MET680A, MET682A, PHE1785B, PHE1830B, PHE1958B, PHE1963B, PHE1983B, PHE2014B, PHE293A, PHE648A, PHE652A, PHE653A, PHE658A, PHE671A, PHE673A, PHE679A, PHE697A, PRO146A, PRO151A, PRO1802B, PRO1825B, PRO1980B, PRO1990B, PRO2078B, PRO2299B, PRO2300B, PRO264A, PRO290A, PRO526A, PRO685A, SER104A, SER109A, SER119A, SER149A, SER157A, SER1784B, SER1787B, SER1788B, SER1791B, SER1838B, SER1839B, SER1946B, SER1949B, SER1955B, SER1959B, SER1991B, SER2011B, SER2173B, SER2264B, SER289A, SER524A, SER650A, SER654A, SER681A, SER695A, SER710A, THR118A, THR135A, THR155A, THR1826B, THR1964B, THR1985B, THR2012B, THR2237B, THR2272B, THR2303B, THR262A, THR263A, THR292A, THR646A, THR657A, THR667A, THR669A, THR83A, THR87A, TRP106A, TRP138A, TRP1817B, TRP1835B, TRP1996B, TRP688A, TYR105A, TYR114A, TYR136A, TYR156A, TYR158A, TYR1786B, TYR1792B, TYR1837B, TYR1971B, TYR1976B, TYR1979B, TYR2332B, TYR656A, TYR664A, VAL101A, VAL103A, VAL137A, VAL162A, VAL165A, VAL178A, VAL1841B, VAL1847B, VAL1962B, VAL1965B, VAL1982B, VAL1998B, VAL2016B, VAL266A, VAL278A, VAL651A, VAL663A, VAL678A, VAL85A