2R6D

crystal form b1

• Total interactions analyzed: 15
• Total true interactions: 10
• Strongest Interaction:
  • Chains: D-E
  • Int. Res.: 168
  • Norm. En. per Res.: -2.4888
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-77.7433	-116.6546	-243.723	-438.1209	180	37	7	12949	7	61	58
A-E	0.0	0.0	-0.0698	-0.0698	2	0	0	24	0	1	0
A-F	-44.7229	29.452	-489.686	-504.957	229	19	31	23839	2	67	61
B-C	-45.721	-0.575	-446.003	-492.299	215	35	32	22947	2	73	69
B-D	0.0	26.1889	-19.7289	6.46	15	0	0	726	0	11	12
B-F	0.0	19.7146	-23.1455	-3.4309	18	1	0	887	0	13	19
C-D	-44.4854	-52.6081	-201.99	-299.0834	166	45	6	12023	3	53	52
D-E	-35.07	-4.1843	-378.871	-418.1253	168	17	33	18995	3	59	56
D-F	0.0	22.3322	-18.3678	3.9644	16	0	0	787	0	9	15
E-F	-70.8075	-104.2983	-186.105	-361.2108	177	39	13	13748	7	44	44

Interface residues

• A-B: ALA100A, ALA100B, ALA106A, ALA16A, ALA19A, ALA244A, ALA260A, ALA29B, ALA303A, ALA30B, ALA348A, ALA348B, ALA34B, ALA350B, ALA390B, ALA59B, ALA72B, ALA75B, ALA76B, ALA95A, ARG107A, ARG107B, ARG117B, ARG195B, ARG202B, ARG250A, ARG264A, ARG297A, ARG302A, ARG302B, ARG306A, ARG307A, ARG330A, ARG344A, ARG344B, ARG351A, ARG351B, ARG365A, ARG381B, ARG420B, ARG61B, ASN101A, ASN101B, ASN421B, ASP194B, ASP204B, ASP27B, ASP291A, ASP292A, ASP300A, ASP320A, ASP389B, ASP391B, ASP60B, ASP66B, CYS253A, GLN12A, GLN18A, GLN201B, GLN245A, GLN246A, GLN261A, GLN326A, GLN362A, GLN388A, GLN388B, GLN419B, GLU103A, GLU103B, GLU111A, GLU149B, GLU15A, GLU17A, GLU241A, GLU341A, GLU341B, GLU352A, GLU352B, GLU354B, GLU36B, GLU387B, GLU63B, GLU73B, GLY266A, GLY327A, GLY329A, GLY422B, GLY62B, GLY85B, ILE108A, ILE14A, ILE183B, ILE290A, ILE296A, ILE301A, ILE325A, ILE342A, ILE37B, ILE392B, ILE39B, LEU115A, LEU205B, LEU240A, LEU247A, LEU263A, LEU268A, LEU26B, LEU31B, LEU324A, LEU346A, LEU346B, LEU349A, LEU349B, LEU38B, LEU56B, LEU67B, LEU74B, LEU80B, LEU89B, LYS112A, LYS267A, LYS304A, LYS347A, LYS347B, LYS418B, MET148B, MET196B, MET242A, MET249A, PHE25B, PRO11A, PRO212A, PRO28B, PRO294A, PRO33B, PRO423B, PRO64B, PRO97A, SER13A, SER198B, SER203B, SER239A, SER243A, SER295A, SER299A, SER328A, SER328B, SER340A, SER343A, SER343B, SER345A, SER345B, SER35B, SER385A, SER77B, SER87B, THR184B, THR197B, THR217A, THR265A, THR293A, THR69B, THR71B, THR98A, TYR104A, TYR104B, TYR105A, TYR321A, VAL102B, VAL109A, VAL20A, VAL298A, VAL32B, VAL424B, VAL58B, VAL65B, VAL68B, VAL70B, VAL86B, VAL96A
• A-E: ARG330E, LEU140A
• A-F: ALA122A, ALA122F, ALA126A, ALA126F, ALA143A, ALA143F, ALA158A, ALA228F, ALA236F, ALA244F, ALA260F, ALA279F, ALA286F, ALA303F, ALA417A, ARG107A, ARG107F, ARG116A, ARG116F, ARG117A, ARG117F, ARG120A, ARG120F, ARG132A, ARG132F, ARG145A, ARG145F, ARG153A, ARG179A, ARG195A, ARG250F, ARG264F, ARG302F, ARG306F, ARG307F, ARG330F, ARG365A, ARG365F, ARG374A, ARG381A, ASN161A, ASN172A, ASN178A, ASN262F, ASN285F, ASP128A, ASP128F, ASP134A, ASP134F, ASP137A, ASP137F, ASP141A, ASP141F, ASP144A, ASP144F, ASP164A, ASP171A, ASP291F, ASP292F, ASP300F, ASP379A, CYS253F, CYS305F, GLN127A, GLN127F, GLN12A, GLN12F, GLN152A, GLN168A, GLN225F, GLN245F, GLN246F, GLN261F, GLN310F, GLN362F, GLN388A, GLN428A, GLU110A, GLU110F, GLU111A, GLU111F, GLU133A, GLU133F, GLU135A, GLU135F, GLU142A, GLU142F, GLU149A, GLU149F, GLU174A, GLU192A, GLU241F, GLU255F, GLU352F, GLU368A, GLU36A, GLU382A, GLU387A, GLU413A, GLY129A, GLY129F, GLY266F, GLY281F, GLY287F, GLY425A, HIS177A, ILE108A, ILE108F, ILE119A, ILE119F, ILE125A, ILE125F, ILE136A, ILE136F, ILE147A, ILE147F, ILE162A, ILE165A, ILE173A, ILE237F, ILE258F, ILE288F, ILE290F, ILE301F, ILE317F, ILE37A, ILE414A, ILE415A, ILE416A, LEU115A, LEU115F, LEU118A, LEU118F, LEU139A, LEU139F, LEU140A, LEU140F, LEU166A, LEU176A, LEU240F, LEU247F, LEU252F, LEU263F, LEU268F, LEU276F, LEU283F, LEU308F, LEU314F, LEU324F, LEU353F, LEU441A, LYS112A, LYS112F, LYS146A, LYS146F, LYS160A, LYS163A, LYS267F, LYS304F, LYS309F, LYS409A, MET148A, MET148F, MET175A, MET196A, MET242F, MET249F, MET251F, MET280F, MET316F, MET376A, MET377A, PHE159A, PHE238F, PHE395A, PRO10A, PRO10F, PRO11A, PRO11F, PRO212F, PRO270F, PRO294F, PRO375A, SER113A, SER124A, SER124F, SER13A, SER13F, SER151A, SER213F, SER239F, SER243F, SER282F, SER284F, SER295F, SER299F, SER312F, SER366A, SER378A, THR121A, THR121F, THR123A, THR123F, THR131A, THR131F, THR169A, THR217F, THR265F, THR269F, THR277F, THR293F, THR426A, TRP273F, TYR130A, TYR130F, TYR170A, TYR289F, TYR321F, TYR397A, VAL114A, VAL114F, VAL150A, VAL167A, VAL235F, VAL248F, VAL318F, VAL367A, VAL424A, VAL427A
• B-C: ALA122B, ALA122C, ALA126B, ALA126C, ALA143B, ALA143C, ALA228B, ALA236B, ALA244B, ALA260B, ALA279B, ALA286B, ALA417C, ARG107B, ARG107C, ARG116B, ARG116C, ARG117B, ARG117C, ARG120B, ARG120C, ARG132B, ARG132C, ARG145B, ARG145C, ARG179C, ARG195C, ARG250B, ARG264B, ARG344C, ARG365B, ARG365C, ARG374C, ARG381C, ASN161C, ASN172C, ASN178C, ASN262B, ASN285B, ASP128B, ASP128C, ASP134B, ASP134C, ASP137B, ASP137C, ASP141B, ASP141C, ASP144B, ASP144C, ASP164C, ASP171C, ASP272B, ASP291B, ASP292B, ASP320B, ASP379C, CYS253B, GLN127B, GLN127C, GLN12B, GLN12C, GLN168C, GLN225B, GLN245B, GLN246B, GLN261B, GLN323B, GLN362B, GLN388C, GLN428C, GLU110B, GLU110C, GLU111B, GLU111C, GLU133B, GLU133C, GLU135B, GLU135C, GLU142B, GLU142C, GLU149B, GLU149C, GLU174C, GLU192C, GLU241B, GLU255B, GLU368B, GLU368C, GLU382C, GLU387C, GLU413C, GLY129B, GLY129C, GLY266B, GLY274B, GLY281B, GLY287B, GLY425C, HIS177C, ILE108B, ILE108C, ILE119B, ILE119C, ILE125B, ILE125C, ILE136B, ILE136C, ILE147B, ILE147C, ILE162C, ILE165C, ILE173C, ILE237B, ILE258B, ILE288B, ILE290B, ILE411C, ILE414C, ILE415C, ILE416C, LEU115B, LEU115C, LEU118B, LEU118C, LEU139B, LEU139C, LEU140B, LEU140C, LEU166C, LEU176C, LEU240B, LEU247B, LEU252B, LEU263B, LEU268B, LEU276B, LEU283B, LEU308B, LEU324B, LEU441C, LYS112B, LYS112C, LYS146B, LYS146C, LYS160C, LYS163C, LYS267B, LYS275B, LYS304B, LYS409C, LYS418C, MET148B, MET148C, MET175C, MET196C, MET242B, MET249B, MET251B, MET278B, MET280B, MET376C, MET377C, PHE395C, PRO10B, PRO10C, PRO11B, PRO11C, PRO212B, PRO270B, PRO294B, PRO375C, PRO423C, SER113B, SER124B, SER124C, SER13B, SER13C, SER213B, SER243B, SER282B, SER284B, SER295B, SER366C, SER378C, SER385C, THR121B, THR121C, THR123B, THR123C, THR131B, THR131C, THR169C, THR217B, THR229B, THR265B, THR269B, THR277B, THR293B, THR426C, TRP273B, TYR130B, TYR130C, TYR170C, TYR289B, TYR321B, TYR397C, VAL114B, VAL114C, VAL138B, VAL167C, VAL235B, VAL248B, VAL367C, VAL424C, VAL427C
• B-D: ALA72D, ALA75D, ALA76D, ARG132B, ARG57D, ARG61D, ASP134B, GLU133B, GLU135B, GLU73D, GLU78D, ILE136B, SER77D, THR131B, TYR130B
• B-F: ALA72B, ALA75B, ALA76B, ARG132F, ARG330F, ARG57B, ARG61B, ASP134F, ASP60B, GLU133F, GLU135F, GLU73B, GLU78B, ILE136F, LEU74B, SER77B, THR131F, TYR130F
• C-D: ALA100C, ALA16C, ALA19C, ALA244C, ALA29D, ALA303C, ALA348C, ALA34D, ALA417D, ALA59D, ALA72D, ALA75D, ALA76D, ALA95C, ARG107C, ARG107D, ARG195D, ARG250C, ARG264C, ARG297C, ARG302C, ARG306C, ARG307C, ARG330C, ARG344C, ARG351C, ARG365C, ARG374D, ARG381D, ARG420D, ARG57D, ARG61D, ASN101C, ASN421D, ASP291C, ASP292C, ASP300C, ASP379D, ASP389D, ASP60D, ASP66D, CYS305C, GLN12C, GLN18C, GLN245C, GLN246C, GLN261C, GLN310C, GLN323C, GLN326C, GLN362C, GLN388D, GLN419D, GLN428D, GLU103C, GLU103D, GLU111C, GLU149D, GLU15C, GLU17C, GLU192D, GLU241C, GLU338D, GLU341C, GLU352C, GLU368D, GLU36D, GLU382D, GLU387D, GLU413D, GLU63D, GLU73D, GLU78D, GLY266C, GLY384D, GLY422D, GLY425D, GLY62D, HIS53D, ILE108C, ILE14C, ILE296C, ILE37D, ILE380D, ILE386D, ILE39D, ILE415D, ILE416D, LEU115C, LEU240C, LEU247C, LEU263C, LEU268C, LEU308C, LEU31D, LEU324C, LEU346C, LEU349C, LEU353C, LEU38D, LEU441D, LEU56D, LEU67D, LEU74D, LEU80D, LEU89D, LYS112C, LYS267C, LYS304C, LYS347C, LYS418D, MET196D, MET242C, MET249C, MET376D, MET377D, MET55D, PHE25D, PHE395D, PRO11C, PRO28D, PRO294C, PRO33D, PRO375D, PRO423D, PRO64D, PRO97C, SER13C, SER213C, SER239C, SER243C, SER295C, SER299C, SER328C, SER345C, SER35D, SER366D, SER378D, SER385D, SER77D, SER90D, THR265C, THR293C, THR426D, THR69D, THR71D, THR98C, TRP273C, TYR104C, TYR105C, TYR321C, VAL102C, VAL109C, VAL20C, VAL248C, VAL298C, VAL32D, VAL393D, VAL424D, VAL427D, VAL58D, VAL65D, VAL68D, VAL70D, VAL86D, VAL96C
• D-E: ALA122D, ALA122E, ALA126D, ALA126E, ALA143D, ALA143E, ALA228D, ALA244D, ALA279D, ALA286D, ALA303D, ALA348D, ARG107D, ARG107E, ARG116D, ARG116E, ARG117D, ARG117E, ARG120D, ARG120E, ARG132D, ARG132E, ARG145D, ARG145E, ARG250D, ARG264D, ARG302D, ARG306D, ARG307D, ASN161E, ASN172E, ASN262D, ASN285D, ASP128D, ASP128E, ASP134D, ASP134E, ASP137D, ASP137E, ASP141D, ASP141E, ASP144D, ASP144E, ASP164E, ASP171E, ASP291D, ASP292D, GLN127D, GLN127E, GLN12D, GLN12E, GLN168E, GLN225D, GLN245D, GLN246D, GLN261D, GLN419E, GLU110D, GLU110E, GLU111D, GLU111E, GLU133D, GLU133E, GLU135D, GLU135E, GLU142D, GLU142E, GLU149D, GLU149E, GLU174E, GLU352D, GLU36E, GLY129D, GLY129E, GLY266D, GLY281D, GLY287D, GLY422E, GLY425E, ILE108D, ILE108E, ILE119D, ILE119E, ILE125D, ILE125E, ILE136D, ILE136E, ILE147D, ILE147E, ILE162E, ILE165E, ILE173E, ILE237D, ILE258D, ILE288D, ILE290D, ILE37E, ILE416E, LEU115D, LEU115E, LEU118D, LEU118E, LEU139D, LEU139E, LEU140D, LEU140E, LEU166E, LEU247D, LEU252D, LEU263D, LEU268D, LEU276D, LEU283D, LEU308D, LYS112D, LYS112E, LYS146D, LYS146E, LYS160E, LYS163E, LYS267D, LYS304D, MET148D, MET148E, MET196E, MET249D, MET251D, MET280D, PRO10D, PRO10E, PRO11D, PRO11E, PRO294D, PRO423E, SER113E, SER124D, SER124E, SER13E, SER243D, SER282D, SER284D, SER299D, SER312D, SER345D, THR121D, THR121E, THR123D, THR123E, THR131D, THR131E, THR169E, THR229D, THR265D, THR277D, THR293D, THR426E, TRP273D, TYR130D, TYR130E, TYR170E, TYR289D, VAL114D, VAL114E, VAL138D, VAL167E, VAL248D, VAL298D, VAL424E
• D-F: ALA72F, ALA75F, ALA76F, ARG132D, ARG330D, ARG57F, ARG61F, ASP134D, GLU133D, GLU135D, GLU73F, GLU78F, ILE136D, SER77F, THR131D, TYR130D
• E-F: ALA100E, ALA106E, ALA16E, ALA19E, ALA228E, ALA244E, ALA260E, ALA279E, ALA286E, ALA303E, ALA417F, ALA59F, ALA72F, ALA75F, ALA76F, ALA93F, ALA95E, ARG107E, ARG107F, ARG117F, ARG145F, ARG195F, ARG250E, ARG264E, ARG297E, ARG302E, ARG306E, ARG307E, ARG330E, ARG344F, ARG351F, ARG365E, ARG381F, ARG420F, ARG61F, ASN101E, ASN161F, ASN172F, ASN262E, ASN285E, ASN421F, ASP144F, ASP164F, ASP171F, ASP291E, ASP292E, ASP389F, ASP391F, ASP66F, CYS253E, GLN12E, GLN168F, GLN18E, GLN225E, GLN245E, GLN246E, GLN261E, GLN323E, GLN326E, GLN362E, GLN388F, GLN419F, GLU103E, GLU103F, GLU111E, GLU149F, GLU15E, GLU174F, GLU17E, GLU241E, GLU255E, GLU352E, GLU368E, GLU36F, GLU382F, GLU387F, GLU63F, GLU73F, GLY266E, GLY281E, GLY287E, GLY329E, GLY384F, GLY422F, GLY425F, GLY62F, ILE108E, ILE147F, ILE14E, ILE162F, ILE165F, ILE173F, ILE237E, ILE258E, ILE288E, ILE290E, ILE37F, LEU166F, LEU240E, LEU247E, LEU252E, LEU263E, LEU268E, LEU26F, LEU276E, LEU283E, LEU308E, LEU324E, LEU67F, LEU74F, LEU80F, LEU89F, LYS112E, LYS146F, LYS160F, LYS163F, LYS267E, LYS304E, LYS418F, MET148F, MET196F, MET242E, MET249E, MET251E, MET280E, MET377F, PHE25F, PRO11E, PRO212E, PRO28F, PRO294E, PRO33F, PRO423F, PRO64F, PRO97E, SER13E, SER213E, SER243E, SER282E, SER284E, SER295E, SER299E, SER345E, SER35F, SER378F, SER383F, SER385F, SER87F, SER90F, THR169F, THR229E, THR265E, THR277E, THR293E, THR69F, THR71F, THR98E, TRP273E, TYR104E, TYR105E, TYR170F, TYR289E, TYR321E, VAL102E, VAL109E, VAL114F, VAL167F, VAL20E, VAL248E, VAL32F, VAL424F, VAL58F, VAL65F, VAL68F, VAL70F, VAL86F, VAL96E