2R4H

crystal structure of a c1190s mutant of the 6th pdz domain of human membrane associated guanylate kinase

• Total interactions analyzed: 3
• Total true interactions: 2
• Strongest Interaction:
  • Chains: A-C
  • Int. Res.: 64
  • Norm. En. per Res.: -3.3654
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-23.5486	-22.106	-96.8046	-142.4592	47	5	1	3828	2	23	24
A-C	-56.1174	22.4581	-181.729	-215.3883	64	15	6	6524	1	23	18

Interface residues

• A-B: ARG78A, ARG78B, ARG80A, ARG80B, ARG85A, ASN56A, ASN56B, ASP2A, ASP2B, GLU51B, GLU54A, GLU54B, GLU58A, GLU58B, GLU7A, GLU7B, GLU9B, GLY57A, GLY57B, ILE55B, LEU53A, LEU53B, LEU81A, LEU81B, LEU83A, LEU83B, LEU8A, LEU8B, LYS45A, LYS61B, LYS84A, LYS84B, MET1A, PHE3A, PHE3B, PHE82A, PHE82B, THR59B, THR5A, THR5B, THR60B, TYR4A, TYR4B, VAL6A, VAL6B, VAL79A, VAL79B
• A-C: ALA35C, ALA40C, ALA68C, ARG10C, ARG20A, ARG20C, ARG23C, ARG33C, ARG47A, ARG85A, ASN26C, ASP28A, ASP2A, ASP50A, GLU24C, GLU51A, GLU70C, GLU87A, GLY11C, GLY14C, GLY16C, GLY21C, GLY22C, GLY49A, GLY86A, HIS65C, ILE48A, ILE52A, ILE52C, ILE55C, ILE69C, ILE72C, LEU19C, LEU29A, LEU29C, LEU32A, LEU32C, LEU34A, LEU53A, LEU81C, LEU8C, LYS13C, LYS73C, LYS84A, MET1A, MET27A, MET27C, MET46A, MET46C, PHE15C, PHE17C, PRO39C, SER18C, SER66C, SER89A, THR88A, TYR25C, TYR30A, TYR30C, TYR4A, VAL31A, VAL31C, VAL79C, VAL90A