2QTW

the crystal structure of pcsk9 at 1.9 angstroms resolution reveals structural homology to resistin within the c-terminal domain

• Total interactions analyzed: 1
• Total true interactions: 1
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 135
  • Norm. En. per Res.: -4.6742
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-152.5706	-47.4444	-430.997	-631.012	135	27	18	15919	2	19	17

Interface residues

• A-B: ALA151A, ALA290B, ALA299B, ALA300B, ALA305B, ALA307B, ALA314B, ALA315B, ALA328B, ALA338B, ALA388B, ALA389B, ALA62A, ALA68A, ARG272B, ARG295B, ARG303B, ARG306B, ARG319B, ARG66A, ARG73A, ASN207B, ASN254B, ASN298B, ASN317B, ASN354B, ASP141A, ASP146A, ASP186B, ASP212B, ASP320B, ASP321B, CYS301B, CYS67A, GLN152A, GLN256B, GLN275B, GLN302B, GLN382B, GLN387B, GLU144A, GLU145A, GLU269B, GLU84A, GLU85A, GLY117A, GLY121A, GLY227B, GLY257B, GLY259B, GLY263B, GLY267B, GLY291B, GLY292B, GLY316B, GLY352B, GLY384B, HIS113A, HIS116A, HIS226B, HIS65A, ILE143A, ILE266B, ILE271B, LEU112A, LEU118A, LEU119A, LEU123A, LEU185B, LEU230B, LEU253B, LEU265B, LEU268B, LEU276B, LEU287B, LEU289B, LEU297B, LEU304B, LEU311B, LEU324B, LEU348B, LEU351B, LEU74A, LEU82A, LEU88A, LYS258B, LYS273B, LYS69A, LYS83A, PHE115A, PHE122A, PHE150A, PHE205B, PHE270B, PHE318B, PHE64A, PRO120A, PRO209B, PRO288B, PRO327B, PRO71A, SER147A, SER148A, SER262B, SER294B, SER326B, SER383B, SER386B, THR187B, THR260B, THR264B, THR313B, THR353B, THR385B, THR61A, THR63A, THR77A, THR86A, TRP72A, TYR142A, TYR293B, TYR325B, TYR78A, VAL114A, VAL124A, VAL149A, VAL252B, VAL261B, VAL285B, VAL296B, VAL309B, VAL336B, VAL79A, VAL80A, VAL81A