2QQL

neuropilin-2 a1a2b1b2 domains in complex with a semaphorin-blocking fab

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-H
  • Int. Res.: 53
  • Norm. En. per Res.: -2.9536
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-H	-18.4616	-17.0636	-121.013	-156.5383	53	8	0	4627	2	13	13
A-L	-8.9677	0.0	-46.1771	-55.1448	30	1	0	1514	0	0	1
H-L	-37.688	-8.3709	209.329	163.2701	197	17	17	19758	1	18	16

Interface residues

• A-H: ALA109A, ALA133A, ARG100H, ARG138A, ARG98H, ASN107A, ASN71A, ASN73A, ASN99H, ASP48A, ASP53H, ASP58H, ASP96H, GLN47A, GLU77A, GLU95H, GLY106A, GLY132A, GLY134A, GLY31H, GLY33H, GLY55H, HIS35H, HIS75A, ILE108A, ILE51H, ILE78A, LEU100H, LEU137A, LYS64H, LYS80A, PHE135A, PHE72A, PHE76A, PHE97H, PRO110A, PRO111A, PRO46A, PRO52H, PRO74A, SER136A, SER54H, THR112A, THR57H, TRP100H, TYR100H, TYR32H, TYR39A, TYR45A, TYR50H, TYR52H, TYR56H, VAL100H
• A-L: ALA133A, ALA32L, ALA91L, ALA93L, ARG138A, ASN73A, ASP28L, ASP48A, GLN27L, GLN47A, GLY44A, GLY68L, HIS75A, ILE2L, ILE40A, LEU137A, LEU95L, PHE135A, PRO46A, PRO74A, PRO96L, SER136A, SER30L, THR31L, THR41A, TRP92L, TYR39A, TYR45A, TYR94L, VAL29L
• H-L: ALA125H, ALA130L, ALA136H, ALA137H, ALA168H, ALA32L, ALA34L, ALA43L, ALA49H, ALA51L, ALA60H, ALA91L, ALA93H, ALA93L, ARG100H, ARG38H, ARG94H, ASN137L, ASN138L, ASN158L, ASN210L, ASP101H, ASP122L, ASP144H, ASP167L, ASP170L, ASP1L, ASP58H, ASP61H, ASP96H, CYS134L, CYS140H, CYS214L, CYS216H, CYS88L, CYS92H, GLN100L, GLN105H, GLN124L, GLN160L, GLN166L, GLN171H, GLN37L, GLN38L, GLN39H, GLN6L, GLN89L, GLN90L, GLU123L, GLU161L, GLU165L, GLU213L, GLU46H, GLU6H, GLU95H, GLY101L, GLY104H, GLY106H, GLY128L, GLY134H, GLY139H, GLY162H, GLY174H, GLY212L, GLY41L, GLY42H, GLY44H, GLY99L, HIS164H, HIS35H, ILE117L, ILE48L, LEU100H, LEU124H, LEU125L, LEU135L, LEU136L, LEU138H, LEU141H, LEU170H, LEU175H, LEU175L, LEU178H, LEU179L, LEU181L, LEU45H, LEU46L, LEU47L, LEU54L, LEU95L, LYS103L, LYS126L, LYS143H, LYS169L, LYS207L, LYS209H, LYS214H, LYS39L, LYS42L, LYS43H, LYS45L, LYS64H, MET100H, PHE116L, PHE118L, PHE122H, PHE139L, PHE166H, PHE209L, PHE53L, PHE98L, PRO119L, PRO120L, PRO123H, PRO126H, PRO167H, PRO40L, PRO44L, PRO96L, SER114L, SER120H, SER121L, SER127H, SER127L, SER128H, SER131L, SER159L, SER161H, SER162L, SER172H, SER173H, SER174L, SER176L, SER177H, SER177L, SER179H, SER180H, SER186H, SER208L, SER215H, SER30L, SER50L, SER52L, SER56L, SER62H, THR129L, THR135H, THR164L, THR165H, THR172L, THR178L, THR180L, THR183H, THR31L, THR57H, THR85L, THR97L, TRP100H, TRP103H, TRP35L, TRP36H, TRP47H, TRP92L, TYR100H, TYR102H, TYR173L, TYR176H, TYR36L, TYR49L, TYR50H, TYR52H, TYR55L, TYR56H, TYR59H, TYR86L, TYR87L, TYR91H, TYR94L, VAL100H, VAL115L, VAL121H, VAL132L, VAL133L, VAL163H, VAL163L, VAL169H, VAL181H, VAL182H, VAL184H, VAL207H, VAL211H, VAL29L, VAL2H, VAL33L, VAL37H, VAL48H, VAL89H