2QQC

e109q mutant of pyruvoyl-dependent arginine decarboxylase from methanococcus jannashii

• Total interactions analyzed: 66
• Total true interactions: 34
• Strongest Interaction:
  • Chains: K-L
  • Int. Res.: 109
  • Norm. En. per Res.: -8.2184
• Hub Node: B(7)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-290.7195	-5.7848	-602.605	-899.1093	116	46	40	21900	1	7	7
A-C	-28.9659	13.7084	-98.3522	-113.6097	32	7	6	3104	0	0	3
A-D	0.0	0.0	-28.6848	-28.6848	22	2	1	1433	0	0	0
A-E	-21.0301	1.4462	-62.5626	-82.1465	33	6	4	2605	0	0	4
A-F	-33.9161	-22.1688	-137.143	-193.2278	59	5	1	5025	4	7	5
A-H	0.0	0.0	-0.005	-0.005	2	0	0	5	0	0	0
B-C	-40.398	-21.6286	-133.49	-195.5166	61	3	1	4951	4	6	5
B-D	0.0	0.0	-44.3835	-44.3835	23	0	0	1679	0	0	0
B-E	0.0	0.0	-63.0161	-63.0161	31	1	5	2670	0	0	0
B-F	0.0	0.0	-40.7132	-40.7132	24	0	0	1629	0	0	0
B-G	0.0	0.0	-25.481	-25.481	32	0	0	1314	0	1	1
B-H	-3.5566	-4.4796	-49.513	-57.5492	41	1	0	2541	1	18	21
B-J	0.0	0.0	-11.9065	-11.9065	14	0	0	385	0	4	1
C-D	-274.6722	-4.0186	-629.808	-908.4988	120	38	42	22522	1	7	8
C-E	-33.4461	-0.019	-103.905	-137.3701	37	3	6	4192	0	2	5
C-F	0.0	0.0	-23.2806	-23.2806	20	5	2	1084	0	0	0
D-E	-20.9946	-27.0929	-157.822	-205.9096	74	8	2	6093	4	8	7
D-F	0.0	0.0	-43.7598	-43.7598	26	2	0	1672	0	0	0
E-F	-285.8183	-5.8922	-627.087	-918.7974	126	35	42	23332	1	7	7
G-H	-291.5554	-6.4012	-598.535	-896.4917	114	34	41	21577	1	6	7
G-I	-18.3307	2.6775	-31.2454	-46.8986	18	5	3	1615	0	0	2
G-J	-34.5606	-36.6078	-126.43	-197.5985	59	6	1	4880	4	7	5
G-K	-20.8014	2.5949	-37.3469	-55.5534	19	5	3	1618	0	0	2
G-L	0.0	0.0	-24.0557	-24.0557	19	1	1	1188	0	0	0
H-I	0.0	0.0	-17.07	-17.07	19	2	2	1094	0	0	0
H-J	0.0	0.0	-42.4011	-42.4011	26	1	0	1643	0	0	0
H-K	-24.4298	-21.6283	-143.912	-189.9701	59	8	1	5229	4	8	5
H-L	0.0	0.0	-45.4379	-45.4379	28	1	0	1702	0	0	0
I-J	-270.7468	-3.0613	-594.77	-868.5781	115	44	42	21779	1	7	7
I-K	-21.5559	1.3879	-33.7722	-53.9402	19	5	3	1613	0	0	1
I-L	-32.5766	-22.0155	-134.142	-188.7341	59	7	1	4998	4	8	5
J-K	0.0	0.0	-24.9547	-24.9547	19	2	1	1174	0	0	0
J-L	0.0	0.0	-42.1335	-42.1335	26	0	0	1621	0	0	0
K-L	-280.6815	-9.1757	-605.949	-895.8062	109	43	41	22063	1	7	7

Interface residues

• A-B: ALA145B, ALA156B, ALA158B, ALA159B, ALA160B, ALA161B, ALA22A, ALA33A, ALA37A, ALA41A, ALA59B, ALA71B, ALA76B, ALA91B, ALA92B, ARG124B, ARG50A, ASN16A, ASN32A, ASN40A, ASN45A, ASN47A, ASP35A, ASP83B, CYS104B, CYS155B, GLN109B, GLU111B, GLU120B, GLU142B, GLU147B, GLU151B, GLU26A, GLU28A, GLU58B, GLU60B, GLY105B, GLY154B, GLY23A, GLY27A, GLY36A, GLY42A, GLY44A, GLY70B, GLY78B, GLY86B, HIS148B, ILE107B, ILE141B, ILE144B, ILE43A, ILE49A, ILE51A, ILE54B, ILE61B, ILE80B, ILE81B, ILE89B, ILE93B, ILE97B, LEU14A, LEU153B, LEU162B, LEU20A, LEU31A, LEU38A, LEU39A, LEU48A, LEU64B, LEU67B, LEU72B, LYS116B, LYS13A, LYS152B, LYS165B, LYS66B, MET108B, MET55B, MET69B, PHE12A, PHE157B, PHE34A, PRO15A, PRO30A, PRO56B, PRO57B, PRO63B, PRO65B, PRO68B, PRO74B, PRO85B, SER143B, SER19A, SER24A, SER25A, SER52A, SER82B, SER90B, SER94B, THR149B, THR17A, THR29A, THR75B, TRP163B, TYR164B, TYR77B, TYR79B, VAL123B, VAL146B, VAL150B, VAL18A, VAL21A, VAL46A, VAL62B, VAL73B, VAL95B
• A-C: ALA10A, ALA10C, ARG50A, ARG50C, ASN45C, ASN47C, ASP35C, HIS9A, HIS9C, ILE43C, ILE49A, ILE49C, ILE51A, LEU14A, LEU31C, LEU38C, LEU48C, LEU8A, LEU8C, LYS13A, LYS13C, PHE12A, PHE12C, PHE34C, PRO15A, PRO7A, PRO7C, SER52A, TYR11A, TYR11C, VAL18A, VAL46C
• A-D: ALA71D, ARG50A, GLY70D, ILE49A, ILE51A, LEU14A, LEU67D, LEU72D, LYS13A, MET69D, PHE12A, PHE157D, PRO15A, PRO68D, PRO74D, SER52A, THR75D, TRP163D, TYR164D, TYR77D, TYR79D, VAL73D
• A-E: ALA10A, ALA10E, ARG50A, ARG50E, ASN16A, ASN47A, ASN6E, ASP35A, GLY44A, HIS9E, ILE43A, ILE49A, ILE49E, ILE51A, ILE51E, LEU14A, LEU14E, LEU31A, LEU38A, LEU48A, LEU8E, LYS13A, PHE12A, PHE12E, PHE34A, PRO15A, PRO15E, PRO7E, SER52E, TYR11A, TYR11E, VAL18E, VAL46A
• A-F: ALA127F, ALA33A, ALA37A, ALA76F, ARG134F, ASN32A, ASN40A, ASN45A, ASN47A, ASP35A, CYS104F, GLN109F, GLU111F, GLU125F, GLU132F, GLU26A, GLU28A, GLY105F, GLY130F, GLY135F, GLY27A, GLY36A, GLY44A, GLY78F, ILE107F, ILE129F, ILE43A, ILE49A, ILE54F, ILE93F, LEU103F, LEU106F, LEU162F, LEU31A, LEU38A, LEU39A, LEU48A, LYS128F, MET108F, MET126F, MET133F, MET55F, PHE131F, PHE34A, PRO30A, PRO56F, PRO57F, PRO74F, SER25A, SER94F, THR122F, THR29A, THR75F, TRP136F, TYR110F, TYR77F, VAL123F, VAL46A, VAL73F
• A-H: LEU20A, LYS66H
• B-C: ALA127B, ALA33C, ALA37C, ALA76B, ARG134B, ASN32C, ASN40C, ASN45C, ASN47C, ASP35C, CYS104B, GLN109B, GLU111B, GLU125B, GLU132B, GLU26C, GLU28C, GLY105B, GLY130B, GLY135B, GLY27C, GLY36C, GLY44C, GLY78B, ILE107B, ILE129B, ILE43C, ILE49C, ILE54B, ILE93B, LEU103B, LEU106B, LEU162B, LEU31C, LEU38C, LEU39C, LEU48C, LYS128B, MET108B, MET126B, MET133B, MET55B, PHE12C, PHE131B, PHE34C, PRO30C, PRO56B, PRO57B, PRO74B, SER25C, SER94B, THR122B, THR29C, THR75B, TRP136B, TYR110B, TYR164B, TYR77B, VAL123B, VAL46C, VAL73B
• B-D: ALA59B, ALA71D, ARG134B, CYS104B, GLY105B, GLY70D, ILE54B, LEU103B, LEU162B, LEU72B, LEU72D, MET55B, MET69D, PRO56B, PRO57B, PRO68D, PRO74B, SER102B, THR75B, TRP136B, TRP163B, TYR164B, VAL73B
• B-E: ALA10E, ALA71B, ARG50E, ASN6E, GLY70B, HIS9E, ILE49E, ILE51E, ILE5E, LEU14E, LEU162B, LEU67B, LEU72B, LEU8E, LYS13E, LYS165B, MET69B, PHE12E, PHE157B, PRO15E, PRO68B, PRO74B, PRO7E, SER52E, THR75B, TRP163B, TYR11E, TYR164B, TYR77B, TYR79B, VAL73B
• B-F: ALA59F, ALA71B, ARG134F, CYS104F, GLY105F, GLY70B, ILE54F, LEU103F, LEU162F, LEU72B, LEU72F, MET55F, MET69B, PRO56F, PRO57F, PRO68B, PRO74F, PRO98F, SER102F, THR75F, TRP136F, TRP163F, TYR164F, VAL73F
• B-G: ALA22G, ALA37G, ALA41G, ALA59B, ARG140B, ASN40G, ASN45G, ASP139B, GLU142B, GLU26G, GLU60B, GLY23G, GLY36G, GLY42G, GLY44G, ILE43G, ILE61B, ILE97B, LEU138B, LEU20G, LEU38G, LEU39G, LYS101B, LYS165B, LYS99B, PRO63B, SER19G, SER24G, SER25G, VAL18G, VAL21G, VAL62B
• B-H: ALA145B, ALA145H, ARG124B, ARG140B, ASP100B, ASP139B, GLU120B, GLU120H, GLU137B, GLU142B, GLU142H, GLU147H, GLU151H, ILE141B, ILE144B, ILE144H, ILE61H, ILE93B, ILE97B, LEU138B, LEU64H, LEU67H, LYS101B, LYS116B, LYS116H, LYS117B, LYS121B, LYS128B, LYS165B, LYS165H, LYS66H, LYS99B, MET69H, PRO63H, PRO65H, SER102B, SER143B, SER143H, SER94B, VAL146H, VAL62H
• B-J: ARG134J, GLU132J, GLY130J, GLY135J, LEU64B, LYS116B, LYS66B, MET133J, PHE131J, PRO63B, PRO65B, SER102J, TRP136J, VAL62B
• C-D: ALA10C, ALA145D, ALA156D, ALA158D, ALA159D, ALA160D, ALA161D, ALA22C, ALA33C, ALA37C, ALA41C, ALA59D, ALA71D, ALA76D, ALA91D, ALA92D, ALA96D, ARG124D, ARG50C, ASN16C, ASN32C, ASN40C, ASN45C, ASN47C, ASP35C, ASP83D, CYS155D, GLN109D, GLU111D, GLU120D, GLU142D, GLU147D, GLU151D, GLU26C, GLU28C, GLU58D, GLU60D, GLY105D, GLY154D, GLY23C, GLY27C, GLY36C, GLY42C, GLY44C, GLY70D, GLY78D, GLY86D, HIS148D, HIS9C, ILE107D, ILE141D, ILE144D, ILE43C, ILE49C, ILE51C, ILE54D, ILE61D, ILE80D, ILE81D, ILE89D, ILE93D, ILE97D, LEU14C, LEU153D, LEU162D, LEU20C, LEU31C, LEU38C, LEU39C, LEU48C, LEU64D, LEU67D, LEU72D, LYS116D, LYS13C, LYS152D, LYS165D, LYS66D, MET108D, MET55D, MET69D, PHE12C, PHE157D, PHE34C, PRO15C, PRO30C, PRO56D, PRO57D, PRO63D, PRO65D, PRO68D, PRO74D, PRO7C, PRO85D, SER143D, SER19C, SER24C, SER25C, SER52C, SER82D, SER90D, SER94D, THR149D, THR17C, THR29C, THR75D, TRP163D, TYR11C, TYR164D, TYR77D, TYR79D, VAL123D, VAL146D, VAL150D, VAL18C, VAL21C, VAL46C, VAL62D, VAL73D, VAL95D
• C-E: ALA10C, ALA10E, ALA3E, ARG50C, ARG50E, ASN16C, ASN47C, ASN47E, ASN6E, ASP35E, GLU4E, GLY44E, HIS9C, HIS9E, ILE43E, ILE49C, ILE49E, ILE51C, ILE5E, LEU14C, LEU31E, LEU38E, LEU48C, LEU48E, LEU8E, LYS13C, LYS13E, PHE12C, PHE12E, PHE34E, PRO15C, PRO7E, SER52C, TYR11C, TYR11E, VAL18C, VAL46E
• C-F: ALA71F, ARG50C, GLY70F, ILE49C, ILE51C, LEU14C, LEU72F, LYS13C, MET69F, PHE12C, PHE157F, PRO15C, PRO68F, SER52C, THR75F, TRP163F, TYR11C, TYR77F, TYR79F, VAL73F
• D-E: ALA10E, ALA127D, ALA33E, ALA37E, ALA71D, ALA76D, ARG134D, ASN32E, ASN40E, ASN45E, ASN47E, ASN6E, ASP35E, CYS104D, GLN109D, GLU111D, GLU125D, GLU132D, GLU26E, GLU28E, GLU4E, GLU58D, GLY105D, GLY130D, GLY135D, GLY27E, GLY36E, GLY44E, GLY70D, GLY78D, HIS9E, ILE107D, ILE129D, ILE43E, ILE49E, ILE54D, ILE5E, ILE93D, LEU103D, LEU106D, LEU162D, LEU31E, LEU38E, LEU39E, LEU48E, LEU72D, LEU8E, LYS128D, MET108D, MET126D, MET133D, MET55D, PHE131D, PHE34E, PRO30E, PRO56D, PRO57D, PRO68D, PRO74D, PRO7E, SER25E, SER94D, THR122D, THR29E, THR75D, TRP136D, TRP163D, TYR110D, TYR11E, TYR164D, TYR77D, VAL123D, VAL46E, VAL73D
• D-F: ALA59D, ALA71F, ARG134D, ASP100D, CYS104D, GLY105D, GLY70F, ILE54D, LEU103D, LEU162D, LEU72D, LEU72F, LYS101D, MET55D, MET69F, PRO56D, PRO57D, PRO68F, PRO74D, PRO98D, SER102D, THR75D, TRP136D, TRP163D, TYR164D, VAL73D
• E-F: ALA10E, ALA145F, ALA156F, ALA158F, ALA159F, ALA160F, ALA161F, ALA22E, ALA33E, ALA37E, ALA3E, ALA41E, ALA59F, ALA71F, ALA76F, ALA91F, ALA92F, ALA96F, ARG124F, ARG50E, ASN16E, ASN32E, ASN40E, ASN45E, ASN47E, ASN6E, ASP35E, ASP83F, CYS104F, CYS155F, GLN109F, GLU111F, GLU120F, GLU142F, GLU147F, GLU151F, GLU26E, GLU28E, GLU4E, GLU58F, GLU60F, GLY105F, GLY154F, GLY23E, GLY27E, GLY36E, GLY42E, GLY44E, GLY70F, GLY78F, GLY86F, HIS148F, HIS9E, ILE107F, ILE141F, ILE144F, ILE43E, ILE49E, ILE51E, ILE54F, ILE5E, ILE61F, ILE80F, ILE81F, ILE89F, ILE93F, ILE97F, LEU14E, LEU153F, LEU162F, LEU20E, LEU31E, LEU38E, LEU39E, LEU48E, LEU64F, LEU67F, LEU72F, LEU8E, LYS116F, LYS13E, LYS152F, LYS165F, LYS66F, MET108F, MET55F, MET69F, PHE12E, PHE157F, PHE34E, PRO15E, PRO30E, PRO56F, PRO57F, PRO63F, PRO65F, PRO68F, PRO74F, PRO7E, PRO85F, SER143F, SER19E, SER24E, SER25E, SER52E, SER82F, SER90F, SER94F, THR149F, THR17E, THR29E, THR75F, TRP163F, TYR11E, TYR164F, TYR77F, TYR79F, VAL123F, VAL146F, VAL150F, VAL18E, VAL21E, VAL46E, VAL62F, VAL73F, VAL95F
• G-H: ALA145H, ALA156H, ALA158H, ALA159H, ALA160H, ALA161H, ALA22G, ALA33G, ALA37G, ALA41G, ALA59H, ALA71H, ALA76H, ALA91H, ALA92H, ARG124H, ARG50G, ASN16G, ASN32G, ASN40G, ASN45G, ASN47G, ASP35G, ASP83H, CYS155H, GLN109H, GLU111H, GLU120H, GLU142H, GLU147H, GLU151H, GLU26G, GLU28G, GLU58H, GLU60H, GLY105H, GLY154H, GLY23G, GLY27G, GLY36G, GLY42G, GLY44G, GLY70H, GLY78H, GLY86H, HIS148H, ILE107H, ILE141H, ILE144H, ILE43G, ILE49G, ILE51G, ILE54H, ILE61H, ILE80H, ILE81H, ILE89H, ILE93H, ILE97H, LEU14G, LEU153H, LEU162H, LEU20G, LEU31G, LEU38G, LEU39G, LEU48G, LEU64H, LEU67H, LEU72H, LYS116H, LYS13G, LYS152H, LYS165H, LYS66H, MET108H, MET55H, MET69H, PHE157H, PHE34G, PRO15G, PRO30G, PRO56H, PRO57H, PRO63H, PRO65H, PRO68H, PRO74H, PRO85H, SER143H, SER19G, SER24G, SER25G, SER52G, SER82H, SER90H, SER94H, THR149H, THR17G, THR29G, THR75H, TRP163H, TYR164H, TYR77H, TYR79H, VAL123H, VAL146H, VAL150H, VAL18G, VAL21G, VAL46G, VAL62H, VAL73H, VAL95H
• G-I: ARG50G, ARG50I, ASN47G, ASP35G, GLY44G, ILE43G, ILE49G, ILE49I, ILE51I, LEU14I, LEU31G, LEU38G, LEU48G, PHE34G, PRO15I, SER52I, VAL18I, VAL46G
• G-J: ALA127J, ALA33G, ALA37G, ALA76J, ARG134J, ASN32G, ASN40G, ASN45G, ASN47G, ASP35G, CYS104J, GLN109J, GLU111J, GLU125J, GLU132J, GLU26G, GLU28G, GLY105J, GLY130J, GLY135J, GLY27G, GLY36G, GLY44G, GLY78J, ILE107J, ILE129J, ILE43G, ILE49G, ILE54J, ILE93J, LEU103J, LEU106J, LEU162J, LEU31G, LEU38G, LEU39G, LEU48G, LYS128J, MET108J, MET126J, MET133J, MET55J, PHE131J, PHE34G, PRO30G, PRO56J, PRO57J, PRO74J, SER25G, SER94J, THR122J, THR29G, THR75J, TRP136J, TYR110J, TYR77J, VAL123J, VAL46G, VAL73J
• G-K: ARG50G, ARG50K, ASN45K, ASN47K, ASP35K, GLY44K, ILE43K, ILE49G, ILE49K, ILE51G, LEU14G, LEU31K, LEU38K, LEU48K, PHE34K, PRO15G, SER52G, VAL18G, VAL46K
• G-L: ALA71L, ARG50G, GLY70L, ILE49G, ILE51G, LEU14G, LEU67L, LEU72L, LYS13G, MET69L, PHE157L, PRO15G, PRO68L, SER52G, THR75L, TRP163L, TYR77L, TYR79L, VAL73L
• H-I: ALA71H, ARG50I, GLY70H, ILE49I, ILE51I, LEU14I, LEU67H, LEU72H, LYS13I, MET69H, PHE157H, PRO15I, PRO68H, SER52I, THR75H, TRP163H, TYR77H, TYR79H, VAL73H
• H-J: ALA59J, ALA71H, ARG134J, ASP100J, CYS104J, GLY105J, GLY70H, ILE54J, LEU103J, LEU162J, LEU72H, LEU72J, LYS101J, MET55J, MET69H, PRO56J, PRO57J, PRO68H, PRO74J, PRO98J, SER102J, THR75J, TRP136J, TRP163J, TYR164J, VAL73J
• H-K: ALA127H, ALA33K, ALA37K, ALA76H, ARG134H, ASN32K, ASN40K, ASN45K, ASN47K, ASP35K, CYS104H, GLN109H, GLU111H, GLU125H, GLU132H, GLU26K, GLU28K, GLY105H, GLY130H, GLY135H, GLY27K, GLY36K, GLY44K, GLY78H, ILE107H, ILE129H, ILE43K, ILE49K, ILE54H, ILE93H, LEU103H, LEU106H, LEU162H, LEU31K, LEU38K, LEU39K, LEU48K, LYS128H, MET108H, MET126H, MET133H, MET55H, PHE131H, PHE34K, PRO30K, PRO56H, PRO57H, PRO74H, SER25K, SER94H, THR122H, THR29K, THR75H, TRP136H, TYR110H, TYR77H, VAL123H, VAL46K, VAL73H
• H-L: ALA59H, ALA71L, ARG134H, ASP100H, CYS104H, CYS155L, GLY105H, GLY70L, ILE54H, LEU103H, LEU162H, LEU72H, LEU72L, LYS101H, MET133H, MET55H, MET69L, PRO56H, PRO57H, PRO68L, PRO74H, PRO98H, SER102H, THR75H, TRP136H, TRP163H, TYR164H, VAL73H
• I-J: ALA145J, ALA156J, ALA158J, ALA159J, ALA160J, ALA161J, ALA22I, ALA33I, ALA37I, ALA41I, ALA59J, ALA71J, ALA76J, ALA91J, ALA92J, ALA96J, ARG124J, ARG50I, ASN16I, ASN32I, ASN40I, ASN45I, ASN47I, ASP35I, ASP83J, CYS155J, GLN109J, GLU111J, GLU120J, GLU142J, GLU147J, GLU151J, GLU26I, GLU28I, GLU58J, GLU60J, GLY105J, GLY154J, GLY23I, GLY27I, GLY36I, GLY42I, GLY44I, GLY70J, GLY78J, GLY86J, HIS148J, ILE107J, ILE141J, ILE144J, ILE43I, ILE49I, ILE51I, ILE54J, ILE61J, ILE80J, ILE81J, ILE89J, ILE93J, ILE97J, LEU14I, LEU153J, LEU162J, LEU20I, LEU31I, LEU38I, LEU39I, LEU48I, LEU64J, LEU67J, LEU72J, LYS116J, LYS13I, LYS152J, LYS165J, LYS66J, MET108J, MET55J, MET69J, PHE157J, PHE34I, PRO15I, PRO30I, PRO56J, PRO57J, PRO63J, PRO65J, PRO68J, PRO74J, PRO85J, SER143J, SER19I, SER24I, SER25I, SER52I, SER82J, SER90J, SER94J, THR149J, THR17I, THR29I, THR75J, TRP163J, TYR164J, TYR77J, TYR79J, VAL123J, VAL146J, VAL150J, VAL18I, VAL21I, VAL46I, VAL62J, VAL73J, VAL95J
• I-K: ARG50I, ARG50K, ASN47I, ASP35I, GLY44I, ILE43I, ILE49I, ILE49K, ILE51I, ILE51K, LEU14K, LEU31I, LEU38I, LEU48I, PHE34I, PRO15K, SER52K, VAL18K, VAL46I
• I-L: ALA127L, ALA33I, ALA37I, ALA76L, ARG134L, ASN32I, ASN40I, ASN45I, ASN47I, ASP35I, CYS104L, GLN109L, GLU111L, GLU125L, GLU132L, GLU26I, GLU28I, GLY105L, GLY130L, GLY135L, GLY27I, GLY36I, GLY44I, GLY78L, ILE107L, ILE129L, ILE43I, ILE49I, ILE54L, ILE93L, LEU103L, LEU106L, LEU162L, LEU31I, LEU38I, LEU39I, LEU48I, LYS128L, MET108L, MET126L, MET133L, MET55L, PHE131L, PHE34I, PRO30I, PRO56L, PRO57L, PRO74L, SER25I, SER94L, THR122L, THR29I, THR75L, TRP136L, TYR110L, TYR77L, VAL123L, VAL46I, VAL73L
• J-K: ALA71J, ARG50K, GLY70J, ILE49K, ILE51K, LEU14K, LEU67J, LEU72J, LYS13K, MET69J, PHE157J, PRO15K, PRO68J, SER52K, THR75J, TRP163J, TYR77J, TYR79J, VAL73J
• J-L: ALA59L, ALA71J, ARG134L, CYS104L, CYS155J, GLY105L, GLY70J, ILE54L, LEU103L, LEU162L, LEU72J, LEU72L, MET133L, MET55L, MET69J, PRO56L, PRO57L, PRO68J, PRO74L, PRO98L, SER102L, THR75L, TRP136L, TRP163L, TYR164L, VAL73L
• K-L: ALA145L, ALA156L, ALA158L, ALA159L, ALA160L, ALA161L, ALA22K, ALA33K, ALA37K, ALA41K, ALA59L, ALA71L, ALA76L, ALA91L, ALA92L, ARG50K, ASN16K, ASN32K, ASN40K, ASN45K, ASN47K, ASP35K, ASP83L, CYS155L, GLN109L, GLU111L, GLU142L, GLU147L, GLU151L, GLU26K, GLU28K, GLU58L, GLU60L, GLY105L, GLY154L, GLY23K, GLY27K, GLY36K, GLY42K, GLY44K, GLY70L, GLY78L, GLY86L, HIS148L, ILE107L, ILE144L, ILE43K, ILE49K, ILE51K, ILE54L, ILE61L, ILE80L, ILE81L, ILE89L, ILE93L, ILE97L, LEU14K, LEU153L, LEU162L, LEU20K, LEU31K, LEU38K, LEU39K, LEU48K, LEU64L, LEU67L, LEU72L, LYS13K, LYS152L, LYS165L, LYS66L, MET108L, MET55L, MET69L, PHE157L, PHE34K, PRO15K, PRO30K, PRO56L, PRO57L, PRO63L, PRO65L, PRO68L, PRO74L, PRO85L, SER143L, SER19K, SER24K, SER25K, SER52K, SER82L, SER90L, SER94L, THR149L, THR17K, THR29K, THR75L, TRP163L, TYR164L, TYR77L, TYR79L, VAL146L, VAL150L, VAL18K, VAL21K, VAL46K, VAL62L, VAL73L, VAL95L