2QM4

crystal structure of human xlf/cernunnos, a non-homologous end-joining factor

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 204
  • Norm. En. per Res.: -4.56
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-67.3529	-73.8261	-721.384	-862.563	199	28	39	30476	7	52	52
A-C	0.0	-1.2672	-25.9611	-27.2283	17	1	0	1235	0	9	4
A-D	0.0	12.1307	-11.7083	0.4224	21	1	1	686	0	4	4
B-D	-6.8325	-35.337	-118.134	-160.3035	59	5	1	4976	2	10	14
C-D	-84.5408	-50.6861	-795.021	-930.2479	204	33	41	32754	6	51	55

Interface residues

• A-B: ALA126A, ALA126B, ALA145A, ALA145B, ALA154A, ALA154B, ALA172A, ALA201A, ALA201B, ALA220A, ALA220B, ARG137A, ARG137B, ARG151A, ARG151B, ARG176A, ARG176B, ARG178A, ARG178B, ASN213A, ASN213B, ASP102A, ASP102B, ASP161A, ASP161B, ASP166A, ASP166B, ASP177A, ASP177B, ASP206A, ASP206B, ASP216A, ASP216B, ASP40A, ASP40B, CYS148A, CYS148B, CYS202A, CYS202B, GLN133A, GLN133B, GLN147A, GLN147B, GLN149A, GLN149B, GLN165A, GLN165B, GLN168A, GLN168B, GLN192A, GLN192B, GLN215A, GLN215B, GLN224A, GLN224B, GLN227A, GLN227B, GLN42A, GLN42B, GLN43A, GLN43B, GLU152A, GLU152B, GLU163A, GLU163B, GLU169A, GLU169B, GLU182A, GLU182B, GLU185A, GLU185B, GLU186A, GLU186B, GLU196A, GLU196B, GLU200A, GLU200B, GLU225A, GLU225B, GLY141A, GLY141B, GLY171A, GLY205A, GLY205B, GLY207A, GLY207B, HIS134A, HIS134B, HIS158A, HIS158B, ILE136A, ILE136B, ILE164A, ILE164B, ILE175B, ILE195A, ILE195B, ILE204A, ILE204B, LEU125A, LEU125B, LEU130A, LEU130B, LEU135A, LEU135B, LEU139A, LEU139B, LEU144A, LEU144B, LEU146A, LEU146B, LEU153A, LEU153B, LEU156A, LEU156B, LEU157A, LEU157B, LEU162A, LEU162B, LEU174A, LEU174B, LEU179A, LEU179B, LEU190A, LEU190B, LEU198A, LEU198B, LEU214A, LEU214B, LEU217A, LEU217B, LEU24A, LEU24B, LEU41A, LEU41B, LYS160A, LYS160B, LYS180A, LYS180B, LYS197A, LYS197B, LYS208A, LYS208B, PHE184A, PHE184B, PHE189A, PHE189B, PHE193A, PHE193B, PHE210A, PHE210B, PRO128A, PRO128B, PRO138A, PRO138B, PRO183A, PRO183B, PRO199A, PRO199B, PRO209A, PRO209B, SER127A, SER127B, SER129A, SER129B, SER132A, SER132B, SER143A, SER143B, SER170A, SER203A, SER203B, SER39A, SER39B, THR155A, THR155B, THR173A, THR181A, THR181B, THR222A, THR222B, THR223A, THR223B, TRP13A, TYR167A, TYR167B, TYR218A, TYR218B, VAL131A, VAL131B, VAL150A, VAL150B, VAL211A, VAL211B, VAL221A, VAL221B, VAL228A, VAL44A, VAL44B
• A-C: ALA58A, ARG57A, ASN187C, ASN62A, GLN192C, GLN56A, GLU191C, GLU196C, GLU60A, ILE195C, LEU61A, LYS59A, LYS63A, PRO199C, SER188C, SER52A, SER55A
• A-D: ALA101A, ALA103A, ASN78D, ASP102A, ASP77D, CYS74D, CYS99A, GLN11D, GLN32D, GLN42A, GLN43A, GLN6D, GLU3D, GLY7D, ILE29D, LEU125A, LEU4D, LYS31D, PHE28D, THR30D, VAL100A
• B-D: ALA101B, ALA103B, ALA126B, ALA67D, ALA70D, ALA71D, ARG107B, ARG57B, ARG64D, ASN120B, ASN62D, ASN78D, ASP102B, ASP50B, ASP98B, CYS123B, CYS74D, GLN48B, GLN56B, GLU111D, GLU2B, GLU47B, GLU5B, GLU60B, GLU92D, GLY114D, GLY33B, HIS122B, HIS46B, HIS75D, ILE105B, LEU104B, LEU112D, LEU115D, LEU125B, LEU130B, LEU4B, LEU61B, LEU65D, LYS59D, LYS63D, PHE121B, PHE72D, PRO116D, PRO128B, PRO68D, PRO69D, SER113D, SER127B, SER129B, SER52B, THR51B, THR66D, TRP45B, TYR34B, VAL100B, VAL49B, VAL53B, VAL54B
• C-D: ALA126C, ALA126D, ALA145C, ALA145D, ALA154C, ALA154D, ALA172C, ALA172D, ALA201C, ALA201D, ALA220C, ALA220D, ARG137C, ARG137D, ARG151C, ARG151D, ARG176C, ARG176D, ARG178C, ARG178D, ASN213C, ASN213D, ASP102C, ASP102D, ASP161C, ASP161D, ASP166C, ASP166D, ASP177C, ASP177D, ASP206D, ASP216C, ASP216D, ASP40C, ASP40D, CYS148C, CYS148D, CYS202C, CYS202D, GLN133C, GLN133D, GLN147C, GLN147D, GLN149C, GLN149D, GLN165C, GLN165D, GLN168C, GLN168D, GLN192C, GLN192D, GLN215C, GLN215D, GLN224C, GLN224D, GLN227D, GLN42C, GLN42D, GLN43C, GLN43D, GLU152C, GLU152D, GLU163C, GLU163D, GLU169C, GLU169D, GLU182C, GLU182D, GLU185C, GLU185D, GLU186C, GLU186D, GLU191C, GLU196C, GLU196D, GLU200C, GLU200D, GLU225C, GLU225D, GLY141C, GLY141D, GLY171C, GLY171D, GLY205C, GLY205D, GLY207C, GLY207D, HIS134C, HIS134D, HIS158C, HIS158D, ILE136C, ILE136D, ILE164C, ILE164D, ILE175C, ILE175D, ILE195C, ILE195D, ILE204C, ILE204D, LEU125C, LEU125D, LEU130C, LEU130D, LEU135C, LEU135D, LEU139C, LEU139D, LEU144C, LEU144D, LEU146C, LEU146D, LEU153C, LEU153D, LEU156C, LEU156D, LEU157C, LEU157D, LEU162C, LEU162D, LEU174C, LEU174D, LEU179C, LEU179D, LEU190C, LEU190D, LEU198C, LEU198D, LEU214C, LEU214D, LEU217C, LEU217D, LEU24C, LEU24D, LEU41C, LEU41D, LYS160C, LYS160D, LYS180C, LYS180D, LYS197C, LYS197D, LYS208C, LYS208D, PHE184C, PHE184D, PHE189C, PHE189D, PHE193C, PHE193D, PHE210C, PHE210D, PRO128C, PRO128D, PRO138C, PRO138D, PRO183C, PRO183D, PRO199C, PRO199D, PRO209C, PRO209D, SER127C, SER127D, SER129C, SER129D, SER132C, SER132D, SER143C, SER143D, SER170C, SER170D, SER188C, SER203C, SER203D, SER39C, SER39D, THR155C, THR155D, THR173C, THR173D, THR181C, THR181D, THR222C, THR222D, THR223C, THR223D, TRP13C, TYR167C, TYR167D, TYR218C, TYR218D, VAL131C, VAL131D, VAL150C, VAL150D, VAL211C, VAL211D, VAL221C, VAL221D, VAL228D, VAL44C, VAL44D