2QKM

the crystal structure of fission yeast mrna decapping enzyme dcp1-dcp2 complex

• Total interactions analyzed: 28
• Total true interactions: 14
• Strongest Interaction:
  • Chains: E-F
  • Int. Res.: 95
  • Norm. En. per Res.: -4.0679
• Hub Node: B(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-67.0772	-35.5897	-261.347	-364.0139	97	16	4	11046	3	22	19
A-C	0.0	33.2153	-73.7632	-40.5479	61	1	0	3566	0	26	23
A-D	0.0	0.0	-0.046	-0.046	6	0	0	19	0	0	3
B-C	0.0	-3.7401	-11.9549	-15.695	22	0	0	814	0	7	4
B-D	-37.2349	-38.3445	-285.946	-361.5254	138	16	1	11327	4	66	67
B-F	-25.7882	3.7412	-136.213	-158.2599	82	15	1	7143	0	4	26
B-H	0.0	0.0	-0.004	-0.004	4	0	0	5	0	3	0
C-D	-31.8776	-12.4846	-205.566	-249.9282	84	9	4	8574	1	19	16
E-F	-68.8676	-29.5939	-287.985	-386.4465	95	14	4	11505	1	22	18
E-G	-6.814	25.4074	-71.4726	-52.8793	61	2	0	3973	0	26	23
E-H	0.0	0.0	-0.2364	-0.2364	5	0	0	53	0	0	3
F-G	0.0	-6.5758	-7.2641	-13.8398	18	0	0	619	0	7	4
F-H	-55.2478	-38.1336	-284.541	-377.9224	137	17	1	11257	6	69	70
G-H	-49.7727	-14.8534	-202.947	-267.573	84	5	4	8827	1	20	16

Interface residues

• A-B: ALA10A, ALA17B, ALA25B, ALA30A, ALA41B, ALA51B, ALA6B, ALA70B, ARG116A, ARG167B, ARG18B, ARG71A, ARG8A, ASN12A, ASN22B, ASN53B, ASN5A, ASN5B, ASN70A, ASN72A, ASN76A, ASN9A, ASP110A, ASP113A, ASP13B, ASP14B, ASP3A, ASP47B, CYS72B, GLN10B, GLN14A, GLN28B, GLN37B, GLN40B, GLN52B, GLU27B, GLU2A, GLU4A, GLU51A, GLU75A, GLY52A, HIS19A, HIS32A, HIS71B, ILE20B, ILE26A, ILE29A, ILE38B, ILE49B, ILE50A, ILE68A, ILE6A, LEU12B, LEU13A, LEU15B, LEU16A, LEU21B, LEU23B, LEU69A, LEU74B, LEU75B, LEU77A, LEU7A, LYS218B, LYS77B, MET1A, MET1B, PHE18A, PHE19B, PHE36B, PHE3B, PHE44B, PHE48B, PHE54A, PHE55A, PRO24B, PRO73B, PRO74A, SER120B, SER16B, SER2B, SER31A, SER49A, SER73A, SER9B, THR4B, THR53A, THR7B, TRP43B, TRP76B, TYR20A, TYR220B, TYR45B, VAL11A, VAL11B, VAL15A, VAL67A
• A-C: ALA30A, ALA34C, ARG116A, ARG127A, ARG8A, ARG92C, ASN112A, ASN119A, ASN5A, ASN70C, ASN72C, ASN9A, ASP110A, ASP110C, ASP113A, ASP28A, ASP39C, ASP3A, ASP91C, GLN37C, GLN43C, GLU123A, GLU2A, GLU4A, GLU51C, GLU75C, HIS32C, ILE117A, ILE120A, ILE26A, ILE27A, ILE29A, ILE50C, ILE6A, ILE95C, LEU13A, LEU46C, LYS122A, LYS44C, LYS47C, LYS58A, MET108C, MET114A, MET1A, PHE109C, PHE118A, PHE38C, PRO111A, PRO111C, PRO74C, SER115A, SER25A, SER31A, SER49C, SER73C, THR48C, TRP107C, TRP45C, TYR36C, TYR93C, VAL90C
• A-D: GLU26D, GLU4A, MET1A, MET1D, PHE48D, PRO111A
• B-C: ALA25B, ARG71C, ASN22B, ASN70C, ASN72C, GLN28B, GLU26B, GLU27B, GLU51C, GLU75C, HIS32C, LEU23B, LEU74B, LYS47C, LYS77B, PHE109C, PRO24B, PRO74C, SER29B, SER49C, SER73C, THR48C
• B-D: ALA227D, ALA254B, ALA25B, ALA41D, ALA51D, ALA85B, ARG167D, ARG172B, ARG172D, ARG33B, ARG33D, ARG50D, ARG62B, ARG91B, ARG91D, ARG95B, ARG95D, ARG99B, ARG99D, ASN157B, ASN157D, ASN159B, ASN159D, ASN170B, ASN170D, ASN247B, ASP131B, ASP131D, ASP133B, ASP133D, ASP136B, ASP136D, ASP138B, ASP163B, ASP163D, ASP251B, ASP255B, ASP47D, ASP87B, ASP88B, CYS139B, CYS35D, GLN169D, GLN28B, GLN37D, GLN40D, GLU134B, GLU134D, GLU160B, GLU160D, GLU245B, GLU26B, GLU27B, GLU27D, GLU32B, GLU32D, GLU39D, GLU46D, GLU83B, GLU84B, GLY168D, GLY60D, HIS42D, HIS82B, ILE130B, ILE130D, ILE141B, ILE156B, ILE162D, ILE166D, ILE223D, ILE248B, ILE96B, ILE96D, LEU34B, LEU59D, LEU61D, LEU74B, LEU90B, LEU90D, LYS129D, LYS132B, LYS132D, LYS231D, LYS244B, LYS246B, LYS77B, LYS80B, LYS93B, LYS93D, MET164D, PHE161B, PHE161D, PHE19D, PHE225D, PHE36D, PHE44D, PHE48D, PHE86B, PHE86D, PHE89B, PHE89D, PRO158B, PRO158D, PRO224D, PRO228D, PRO24B, PRO97B, PRO97D, SER135B, SER135D, SER153B, SER154B, SER249B, SER258B, SER29B, SER30B, SER58D, SER79B, THR165D, THR243B, THR94B, THR94D, TRP232D, TRP43D, TRP76B, TRP78B, TYR174B, TYR174D, TYR220D, TYR45D, TYR92B, TYR92D, VAL137B, VAL171D, VAL31B, VAL81B, VAL98B
• B-F: ALA256B, ALA256F, ALA66B, ALA66F, ALA70B, ALA70F, ASN210B, ASN237B, ASN237F, ASN240B, ASN240F, ASN241B, ASN241F, ASP13B, ASP13F, ASP255B, ASP255F, ASP54B, ASP54F, GLN10B, GLN10F, GLN259B, GLN259F, GLN55B, GLN55F, HIS71B, HIS71F, ILE233B, ILE233F, ILE238B, ILE238F, LEU12B, LEU12F, LEU260B, LEU260F, LEU261B, LEU261F, LEU263B, LEU263F, LEU264B, LEU264F, LEU56B, LEU56F, LEU59B, LEU59F, LYS209B, LYS209F, LYS231B, LYS231F, LYS234B, LYS234F, LYS235B, LYS235F, LYS265B, LYS265F, LYS67B, LYS67F, PHE64B, PHE64F, PHE8B, PHE8F, PRO57B, PRO57F, SER258B, SER262B, SER262F, SER266B, SER266F, SER58B, SER58F, SER9B, SER9F, THR242B, THR242F, THR7B, THR7F, TYR45B, TYR45F, VAL11B, VAL11F, VAL63B, VAL63F
• B-H: ASP133H, GLN55B, LYS209B, SER135H
• C-D: ALA10C, ALA17D, ALA25D, ALA30C, ALA41D, ALA51D, ALA6D, ARG18D, ARG33D, ARG71C, ARG8C, ASN12C, ASN22D, ASN5C, ASN5D, ASN70C, ASN72C, ASN76C, ASN9C, ASP110C, ASP113C, ASP13D, ASP14D, ASP47D, CYS72D, GLN10D, GLN14C, GLN28D, GLN37D, GLN40D, GLN52D, GLU26D, GLU27D, GLU4C, GLU51C, GLU75C, GLY52C, HIS19C, HIS32C, HIS71D, ILE20D, ILE26C, ILE29C, ILE49D, ILE50C, ILE68C, LEU12D, LEU13C, LEU15D, LEU16C, LEU21D, LEU23D, LEU69C, LEU77C, LEU7C, LYS77D, MET1D, PHE109C, PHE18C, PHE19D, PHE36D, PHE3D, PHE44D, PHE48D, PHE54C, PHE55C, PRO111C, PRO24D, PRO74C, SER16D, SER2D, SER31C, SER73C, SER9D, THR4D, THR53C, THR7D, TRP76D, TRP78D, TYR20C, VAL11C, VAL11D, VAL15C, VAL67C
• E-F: ALA10E, ALA17F, ALA25F, ALA30E, ALA41F, ALA51F, ALA6F, ALA70F, ARG116E, ARG167F, ARG18F, ARG71E, ARG8E, ASN12E, ASN22F, ASN5E, ASN5F, ASN70E, ASN72E, ASN76E, ASN9E, ASP110E, ASP113E, ASP13F, ASP14F, ASP3E, ASP47F, CYS72F, GLN10F, GLN14E, GLN28F, GLN37F, GLN40F, GLN52F, GLU27F, GLU2E, GLU4E, GLU51E, GLU75E, GLY52E, HIS19E, HIS32E, HIS71F, ILE20F, ILE26E, ILE29E, ILE38F, ILE49F, ILE50E, ILE68E, ILE6E, LEU12F, LEU13E, LEU15F, LEU16E, LEU21F, LEU23F, LEU69E, LEU74F, LEU75F, LEU77E, LEU7E, LYS77F, MET1E, MET1F, PHE18E, PHE19F, PHE36F, PHE3F, PHE44F, PHE48F, PHE54E, PHE55E, PRO24F, PRO73F, PRO74E, SER120F, SER16F, SER2F, SER31E, SER49E, SER73E, SER9F, THR4F, THR53E, THR7F, TRP43F, TRP76F, TYR20E, TYR220F, TYR45F, VAL11E, VAL11F, VAL15E, VAL67E
• E-G: ALA34G, ARG116E, ARG127E, ARG8E, ARG92G, ASN112E, ASN119E, ASN5E, ASN70G, ASN72G, ASN9E, ASP110E, ASP110G, ASP113E, ASP28E, ASP39G, ASP3E, ASP91G, GLN37G, GLN43G, GLU123E, GLU24E, GLU2E, GLU4E, GLU75G, HIS32G, ILE117E, ILE120E, ILE26E, ILE27E, ILE29E, ILE50G, ILE6E, ILE95G, LEU13E, LEU46G, LYS122E, LYS44G, LYS47G, LYS58E, MET108G, MET114E, MET1E, PHE109G, PHE118E, PHE38G, PRO111E, PRO111G, PRO74G, SER115E, SER25E, SER42G, SER49G, SER73G, THR48G, TRP107G, TRP45G, TYR36G, TYR93G, VAL35G, VAL90G
• E-H: GLN52H, GLU4E, MET1E, MET1H, PHE48H
• F-G: ALA25F, ARG71G, ASN72G, GLN28F, GLU26F, GLU51G, GLU75G, HIS32G, LEU23F, LEU74F, LYS47G, LYS77F, PHE109G, PRO24F, PRO74G, SER29F, SER49G, SER73G
• F-H: ALA227H, ALA254F, ALA25F, ALA41H, ALA51H, ALA85F, ARG167H, ARG172F, ARG172H, ARG33F, ARG33H, ARG50H, ARG62F, ARG91F, ARG91H, ARG95F, ARG95H, ARG99F, ARG99H, ASN157F, ASN157H, ASN159F, ASN159H, ASN170F, ASN170H, ASN247F, ASP131F, ASP131H, ASP133F, ASP133H, ASP136F, ASP136H, ASP138F, ASP163F, ASP163H, ASP251F, ASP255F, ASP47H, ASP88F, CYS139F, CYS35H, GLN169H, GLN259F, GLN28F, GLN37H, GLN40H, GLU134F, GLU134H, GLU160F, GLU160H, GLU245F, GLU26F, GLU27F, GLU27H, GLU32F, GLU32H, GLU39H, GLU46H, GLU83F, GLU84F, GLY168H, GLY60H, HIS42H, HIS82F, ILE130F, ILE130H, ILE141F, ILE156F, ILE162H, ILE166H, ILE223H, ILE96F, ILE96H, LEU34F, LEU59H, LEU61H, LEU74F, LEU90H, LYS129H, LYS132F, LYS132H, LYS231H, LYS235H, LYS244F, LYS246F, LYS77F, LYS80F, LYS93F, LYS93H, MET164H, PHE161F, PHE161H, PHE19H, PHE225H, PHE36H, PHE44H, PHE48H, PHE86F, PHE89F, PHE89H, PRO158F, PRO158H, PRO224H, PRO228H, PRO24F, PRO57H, PRO97F, PRO97H, SER135F, SER135H, SER153F, SER154F, SER249F, SER258F, SER29F, SER30F, SER58H, SER79F, THR165H, THR243F, THR94F, THR94H, TRP232H, TRP43H, TRP76F, TRP78F, TYR174F, TYR174H, TYR45H, TYR92F, TYR92H, VAL137F, VAL137H, VAL171H, VAL31F, VAL81F, VAL98F
• G-H: ALA17H, ALA25H, ALA30G, ALA41H, ALA51H, ALA6H, ARG18H, ARG71G, ARG8G, ASN112G, ASN12G, ASN22H, ASN5G, ASN5H, ASN70G, ASN72G, ASN76G, ASN9G, ASP110G, ASP113G, ASP13H, ASP14H, ASP47H, CYS72H, GLN10H, GLN14G, GLN28H, GLN37H, GLN40H, GLN52H, GLU26H, GLU27H, GLU4G, GLU51G, GLU75G, GLY52G, HIS19G, HIS32G, HIS71H, ILE20H, ILE26G, ILE29G, ILE49H, ILE50G, ILE68G, LEU12H, LEU13G, LEU15H, LEU16G, LEU21H, LEU23H, LEU69G, LEU77G, LEU7G, LYS77H, MET1H, PHE109G, PHE18G, PHE19H, PHE36H, PHE3H, PHE44H, PHE48H, PHE54G, PHE55G, PHE8H, PRO111G, PRO24H, PRO74G, SER16H, SER29H, SER2H, SER31G, SER73G, SER9H, THR4H, THR53G, THR7H, TRP78H, TYR20G, VAL11G, VAL11H, VAL15G, VAL67G