2Q8D

crystal structure of jmj2d2a in ternary complex with histone h3-k36me2 and succinate

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-G
  • Int. Res.: 33
  • Norm. En. per Res.: -2.7588
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-12.1548	8.6568	-110.71	-114.208	71	4	0	4764	0	32	28
A-F	-17.737	0.0	-50.9559	-68.6929	26	2	1	1933	0	0	0
B-G	-19.2067	0.0	-71.8328	-91.0395	33	3	2	2576	0	0	0

Interface residues

• A-B: ALA12B, ALA223A, ALA2A, ALA39B, ALA42B, ARG110B, ARG119B, ARG13B, ARG218A, ARG221A, ARG41A, ARG41B, ASN9B, ASP258B, ASP342A, CYS107B, GLN37B, GLU113B, GLU115B, GLU116B, GLU214A, GLU220A, GLU6A, GLY225A, GLY254A, GLY38B, HIS215A, HIS343A, ILE14B, ILE255A, ILE341A, ILE34B, LEU219A, LEU222A, LEU248A, LEU250A, LEU81A, LYS217A, LYS224A, LYS251A, LYS252A, LYS259B, LYS46B, MET15B, MET1A, MET249A, PHE114B, PHE17B, PHE226A, PHE227A, PHE257A, PRO109B, PRO10B, PRO228A, PRO256A, SER112B, SER11B, SER36B, SER3A, SER79A, THR108B, THR16B, THR261B, THR344A, TYR111B, TYR18B, TYR253A, TYR33B, VAL260B, VAL340A, VAL48B
• A-F: ASN137A, ASN172A, ASP135A, ASP191A, ASP311A, GLU169A, GLY170A, GLY33F, GLY34F, ILE166A, ILE168A, ILE315A, LEU305A, LYS241A, LYS310A, LYS314A, MET192A, MET312A, SER316A, THR167A, THR173A, TYR175A, VAL160A, VAL171A, VAL313A, VAL35F
• B-G: ASN137B, ASN172B, ASP135B, ASP191B, ASP311B, ASP318B, GLU161B, GLU169B, GLY165B, GLY170B, GLY33G, GLY34G, ILE166B, ILE168B, ILE315B, LYS241B, LYS310B, LYS314B, MET192B, MET312B, MET317B, PHE320B, SER164B, SER316B, THR167B, THR173B, THR32G, TYR175B, VAL160B, VAL171B, VAL313B, VAL319B, VAL35G