2Q8B

structure of the malaria antigen ama1 in complex with a growth- inhibitory antibody

• Total interactions analyzed: 3
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-H
  • Int. Res.: 87
  • Norm. En. per Res.: -3.5019
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-L	-31.9367	-24.7749	-93.1122	-149.8238	45	4	0	3392	6	10	10
A-H	-35.2771	-21.8959	-247.496	-304.669	87	10	1	9000	0	25	32
L-H	-17.7741	6.206	-418.901	-430.4691	161	11	6	15972	0	17	16

Interface residues

• A-L: ALA51L, ARG199A, ARG54L, ARG96L, ASN31L, ASP196A, ASP204A, ASP244A, ASP32L, GLN89L, GLN90L, GLU187A, GLU197A, GLY57L, GLY91L, HIS200A, ILE48L, ILE53L, LEU189A, LEU195A, LEU46L, LYS203A, LYS209A, LYS246A, LYS45L, MET190A, MET193A, MET198A, PHE201A, PHE92L, PRO188A, PRO192A, SER191A, SER93L, THR194A, THR56L, TRP35L, TYR202A, TYR36L, TYR49L, TYR50L, TYR55L, VAL33L, VAL34L, VAL58L
• A-H: ALA221A, ALA54H, ARG199A, ARG219A, ARG50H, ASN205A, ASN223A, ASN228A, ASN233A, ASN55H, ASN77H, ASP196A, ASP204A, ASP227A, ASP229A, ASP31H, ASP52H, ASP73H, GLN104H, GLN3H, GLN5H, GLU187A, GLU197A, GLU1H, GLU59H, GLY103H, GLY222A, GLY26H, HIS100H, HIS200A, HIS220A, HIS35H, ILE225A, ILE23H, ILE249A, ILE29H, ILE51H, LEU189A, LEU211A, LEU4H, LEU98H, LYS203A, LYS206A, LYS209A, LYS230A, LYS235A, LYS28H, LYS30H, MET190A, MET193A, MET198A, MET224A, MET34H, PHE101H, PHE183A, PHE201A, PHE27H, PRO184A, PRO185A, PRO188A, PRO192A, PRO226A, PRO53H, SER191A, SER232A, SER25H, SER33H, SER75H, SER76H, SER99H, THR171A, THR186A, THR194A, THR32H, THR74H, THR78H, THR97H, TRP102H, TRP47H, TYR202A, TYR207A, TYR234A, TYR236A, TYR251A, VAL208A, VAL24H, VAL2H
• L-H: ALA124H, ALA130L, ALA167H, ARG211L, ARG50H, ARG96L, ASN137L, ASN138L, ASN161L, ASN210L, ASP165L, ASP167L, ASP170L, ASP52H, ASP61H, CYS127H, CYS134L, CYS139H, CYS88L, CYS96H, GLN104H, GLN124L, GLN170H, GLN37L, GLN38L, GLN39H, GLN42L, GLN43H, GLN6H, GLN89L, GLN90L, GLU123L, GLU210H, GLU213L, GLU42H, GLU46H, GLU59H, GLY100L, GLY101L, GLY103H, GLY105H, GLY126H, GLY128L, GLY129L, GLY138H, GLY41L, GLY44H, GLY49H, GLY91L, GLY99L, HIS100H, HIS163H, HIS35H, ILE117L, ILE2L, ILE48H, LEU123H, LEU125L, LEU136L, LEU137H, LEU140H, LEU160L, LEU168H, LEU169H, LEU179L, LEU181L, LEU209H, LEU45H, LEU46L, LYS103L, LYS142H, LYS142L, LYS169L, LYS207H, LYS207L, LYS208H, LYS38H, LYS45L, LYS63H, MET175L, MET176H, PHE101H, PHE10L, PHE118L, PHE135L, PHE139L, PHE165H, PHE209L, PHE64H, PHE87L, PHE98L, PRO119L, PRO120L, PRO122H, PRO125H, PRO166H, PRO44L, PRO62H, PRO95L, SER116L, SER119H, SER121L, SER122L, SER127L, SER131L, SER134H, SER161H, SER162L, SER171H, SER174L, SER176L, SER177H, SER177L, SER178H, SER179H, SER1L, SER208L, SER33H, SER43L, SER93L, SER94L, SER99H, THR114L, THR126L, THR136H, THR164H, THR164L, THR172L, THR175H, THR178L, THR180L, THR181H, THR97H, THR97L, TRP102H, TRP153H, TRP163L, TRP187H, TRP36H, TRP47H, TYR121H, TYR173L, TYR36L, TYR49L, TYR55L, TYR60H, TYR86L, TYR95H, VAL115L, VAL120H, VAL132L, VAL133L, VAL135H, VAL141H, VAL159L, VAL162H, VAL180H, VAL34L, VAL37H, VAL85L, VAL93H