2Q1E

altered dimer interface decreases stability in an amyloidogenic kappa1 bence jones protein.

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: A-B
  • Int. Res.: 67
  • Norm. En. per Res.: -2.9932
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-29.7438	0.0	-170.802	-200.5458	67	7	11	7062	0	6	0
B-D	0.0	0.0	-0.0003	-0.0003	2	0	0	1	0	0	1
C-D	-21.9669	-11.7927	-144.448	-178.2076	68	10	12	7389	0	6	0

Interface residues

• A-B: ALA-1A, ALA-1B, ALA43A, ALA43B, ASN93A, ASN93B, ASP1A, ASP1B, CYS88A, CYS88B, GLN27B, GLN37A, GLN37B, GLN38A, GLN38B, GLN3A, GLN3B, GLN42A, GLN42B, GLN89A, GLN89B, GLN90A, GLN90B, GLY41A, GLY41B, GLY99A, GLY99B, HIS87A, HIS87B, ILE2A, ILE2B, ILE34A, ILE34B, ILE48A, ILE48B, LEU46A, LEU46B, LEU47A, LEU47B, LEU94A, LEU94B, LYS39A, LYS39B, LYS45A, LYS45B, PHE98A, PHE98B, PRO40A, PRO40B, PRO44A, PRO44B, PRO95A, PRO95B, THR0A, THR0B, THR97A, THR97B, TRP35A, TRP35B, TYR36A, TYR36B, TYR49A, TYR49B, TYR91A, TYR91B, TYR96A, TYR96B
• B-D: LYS103B, SER10D
• C-D: ALA-1C, ALA-1D, ALA43C, ALA43D, ASN93C, ASN93D, ASP1C, ASP1D, CYS88C, CYS88D, GLN100C, GLN100D, GLN37C, GLN37D, GLN38C, GLN38D, GLN3C, GLN3D, GLN42C, GLN42D, GLN89C, GLN89D, GLN90C, GLN90D, GLY41C, GLY41D, GLY99C, GLY99D, HIS87C, HIS87D, ILE2C, ILE2D, ILE34C, ILE34D, ILE48C, ILE48D, LEU46C, LEU46D, LEU47C, LEU47D, LEU94C, LEU94D, LYS39C, LYS39D, LYS45C, LYS45D, PHE98C, PHE98D, PRO40C, PRO40D, PRO44C, PRO44D, PRO95C, PRO95D, THR0C, THR0D, THR97C, THR97D, TRP35C, TRP35D, TYR36C, TYR36D, TYR49C, TYR49D, TYR91C, TYR91D, TYR96C, TYR96D