2PV9

crystal structure of murine thrombin in complex with the extracellular fragment of murine par4

• Total interactions analyzed: 3
• Total true interactions: 2
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 102
  • Norm. En. per Res.: -3.6163
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-110.4066	-42.7215	322.466	169.3379	119	50	5	20443	11	50	42
B-C	-54.263	-61.7934	-252.803	-368.8595	102	42	0	11015	4	23	18

Interface residues

• A-B: ALA132B, ALA1A, ALA22B, ALA27B, ARG131B, ARG137B, ARG206B, ARG236B, ARG4A, ARG50B, ASN159B, ASN1A, ASN204B, ASN205B, ASP116B, ASP125B, ASP14A, ASP1A, ASP21B, ASP243B, ASP49B, CYS122B, CYS1A, GLN127B, GLN209B, GLN239B, GLN244B, GLN30B, GLU14A, GLU1A, GLU23B, GLU8A, GLY133B, GLY136B, GLY14A, GLY1A, GLY25B, GLY2A, HIS119B, HIS1A, ILE118B, ILE14A, ILE162B, ILE238B, ILE242B, ILE26B, ILE47B, LEU105B, LEU123B, LEU129B, LEU12A, LEU130B, LEU14A, LEU160B, LEU1A, LEU3A, LEU46B, LEU53B, LEU6A, LYS107B, LYS10A, LYS126B, LYS135B, LYS13A, LYS14A, LYS186B, LYS1A, LYS202B, LYS235B, LYS240B, LYS24B, LYS9A, MET201B, MET210B, PHE114B, PHE184B, PHE199B, PHE1A, PHE204B, PHE232B, PHE245B, PHE7A, PRO111B, PRO113B, PRO120B, PRO124B, PRO161B, PRO204B, PRO28B, PRO5A, SER115B, SER11A, SER129B, SER14A, SER203B, SER48B, THR128B, THR129B, THR14A, THR186B, THR1A, TRP207B, TRP20B, TRP237B, TRP29B, TRP51B, TYR117B, TYR134B, TYR14A, TYR208B, VAL112B, VAL121B, VAL129B, VAL138B, VAL157B, VAL158B, VAL200B, VAL241B, VAL52B
• B-C: ALA183B, ALA190B, ALA195B, ALA55B, ALA67C, ARG145B, ARG173B, ARG175B, ARG221B, ARG35B, ARG59C, ARG73B, ARG97B, ASN143B, ASN149B, ASN57C, ASN60B, ASN68C, ASN95B, ASN98B, ASP100B, ASP102B, ASP189B, ASP194B, ASP221B, ASP54C, ASP60B, ASP69C, ASP71C, CYS191B, CYS220B, CYS42B, CYS58B, CYS66C, GLN151B, GLU146B, GLU192B, GLU217B, GLU39B, GLU74C, GLU97B, GLY140B, GLY142B, GLY193B, GLY196B, GLY197B, GLY216B, GLY219B, GLY226B, GLY43B, GLY60C, GLY63C, HIS57B, ILE149B, ILE150B, ILE16B, ILE174B, ILE176B, ILE212B, LEU160B, LEU33B, LEU40B, LEU41B, LEU73C, LEU75C, LEU99B, LYS224B, LYS51C, LYS55C, LYS60B, LYS64C, MET180B, MET32B, PHE227B, PHE34B, PHE60B, PHE65C, PRO152B, PRO56C, PRO58C, PRO60B, PRO62C, PRO76C, SER214B, SER53C, SER70C, THR147B, THR149B, THR172B, TRP141B, TRP148B, TRP215B, TRP60B, TRP96B, TYR225B, TYR228B, TYR60B, TYR61C, TYR94B, VAL138B, VAL17B, VAL213B