2PUX

crystal structure of murine thrombin in complex with the extracellular fragment of murine par3

• Total interactions analyzed: 3
• Total true interactions: 2
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 48
  • Norm. En. per Res.: -5.8614
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-119.1846	-44.5301	83.8877	-79.8271	115	49	5	19769	11	48	41
B-C	-53.0159	-53.1108	-175.22	-281.3467	48	8	3	6453	2	30	13

Interface residues

• A-B: ALA132B, ALA1A, ALA22B, ALA27B, ARG131B, ARG137B, ARG206B, ARG236B, ARG4A, ARG50B, ASN159B, ASN1A, ASN204B, ASN205B, ASP116B, ASP125B, ASP14A, ASP1A, ASP21B, ASP243B, ASP49B, CYS122B, CYS1A, GLN209B, GLN239B, GLN244B, GLU14A, GLU1A, GLU23B, GLU8A, GLY133B, GLY136B, GLY14A, GLY1A, GLY25B, GLY2A, HIS119B, HIS1A, ILE118B, ILE14A, ILE162B, ILE238B, ILE242B, ILE26B, ILE47B, LEU105B, LEU123B, LEU129B, LEU12A, LEU130B, LEU14A, LEU160B, LEU1A, LEU3A, LEU46B, LEU53B, LEU6A, LYS107B, LYS10A, LYS126B, LYS135B, LYS13A, LYS14A, LYS186B, LYS1A, LYS202B, LYS235B, LYS240B, LYS24B, LYS9A, MET201B, MET210B, PHE114B, PHE184B, PHE199B, PHE1A, PHE204B, PHE232B, PHE245B, PHE7A, PRO111B, PRO113B, PRO120B, PRO124B, PRO161B, PRO204B, PRO28B, PRO5A, SER115B, SER11A, SER129B, SER14A, SER203B, SER48B, THR128B, THR139B, THR14A, THR1A, TRP207B, TRP20B, TRP237B, TRP29B, TRP51B, TYR117B, TYR134B, TYR14A, TYR208B, VAL112B, VAL121B, VAL138B, VAL157B, VAL158B, VAL200B, VAL241B, VAL52B
• B-C: ARG35B, ARG67B, ARG73B, ARG75B, ARG77B, ASN45C, ASN78B, ASP54C, GLN151B, GLN38B, GLU39B, GLU48C, GLU49C, GLU56C, GLU77B, GLU80B, ILE118B, ILE55C, ILE68B, ILE82B, LEU108B, LEU40B, LEU41B, LEU52C, LEU65B, LYS109B, LYS110B, LYS36B, LYS70B, LYS81B, MET32B, MET84B, PHE34B, PHE47C, PHE50C, PRO111B, PRO113B, PRO37B, PRO51C, SER53C, SER72B, SER83B, THR46C, THR74B, TRP141B, TYR76B, VAL112B, VAL66B