2PSM

crystal structure of interleukin 15 in complex with interleukin 15 receptor alpha

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 66
  • Norm. En. per Res.: -6.0783
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-F	-53.5039	-141.3966	-191.199	-386.0995	65	10	2	7031	12	39	20
A-B	-11.2001	52.7285	-160.616	-119.0877	63	7	0	5752	0	21	19
B-C	-59.5267	-150.7568	-190.883	-401.1665	66	9	2	7243	13	40	21

Interface residues

• A-F: ALA38F, ARG25F, ARG27F, ARG36F, ARG66F, ASN41A, ASN56A, ASP22A, ASP67F, CYS30F, CYS42A, CYS64F, CYS88A, GLN48A, GLU45F, GLU46A, GLU53A, GLU87A, GLU89A, GLU90A, GLU92A, GLU93A, GLY39F, HIS20A, HIS52A, ILE19A, ILE21A, ILE44F, ILE50A, ILE65F, LEU25A, LEU43F, LEU44A, LEU45A, LEU47A, LEU51A, LEU62F, LEU70F, LEU91A, LYS35F, LYS37F, LYS63F, LYS86A, LYS94A, PHE34F, PHE43A, PHE96A, PHE99A, PRO60F, PRO68F, SER41F, SER55A, SER61F, SER69F, THR23A, THR24A, THR27A, THR40F, THR42F, THR58F, THR59F, TYR26A, TYR54A, VAL47F, VAL49A
• A-B: ARG105A, ARG105B, ARG6A, ARG6B, ASN112A, ASN112B, ASP4A, ASP4B, ASP8A, ASP8B, GLN101A, GLN101B, GLN108A, GLN108B, GLN17A, GLN17B, GLU10A, GLU10B, GLU13A, GLU13B, GLU98A, GLU98B, HIS20A, ILE104A, ILE104B, ILE111A, ILE111B, ILE12A, ILE12B, ILE16A, ILE16B, ILE19A, ILE19B, ILE3A, ILE3B, LEU100A, LEU100B, LEU15A, LEU15B, LEU9A, LEU9B, LYS11A, LYS11B, LYS94A, LYS94B, MET109A, MET109B, SER102A, SER102B, SER14A, SER14B, SER18A, SER18B, THR95A, THR95B, THR97A, THR97B, TYR7A, TYR7B, VAL107A, VAL107B, VAL5A, VAL5B
• B-C: ALA38C, ALA71C, ARG25C, ARG27C, ARG36C, ARG66C, ASN41B, ASP22B, ASP67C, CYS30C, CYS42B, CYS64C, CYS88B, GLN48B, GLU26C, GLU45C, GLU46B, GLU53B, GLU87B, GLU89B, GLU90B, GLU92B, GLU93B, GLY39C, HIS20B, HIS52B, ILE19B, ILE21B, ILE44C, ILE50B, ILE65C, LEU25B, LEU43C, LEU44B, LEU45B, LEU47B, LEU51B, LEU62C, LEU70C, LEU91B, LYS35C, LYS37C, LYS63C, LYS86B, LYS94B, PHE34C, PHE43B, PHE96B, PHE99B, PRO60C, PRO68C, SER41C, SER55B, SER61C, SER69C, THR23B, THR24B, THR27B, THR40C, THR42C, THR58C, THR59C, TYR26B, TYR54B, VAL47C, VAL49B