2PLS

structural genomics, the crystal structure of the corc/hlyc transporter associated domain of a cbs domain protein from chlorobium tepidum tls

• Total interactions analyzed: 66
• Total true interactions: 25
• Strongest Interaction:
  • Chains: C-K
  • Int. Res.: 41
  • Norm. En. per Res.: -3.2053
• Hub Node: B(8)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-29.5856	6.556	-96.5087	-119.5383	45	5	1	3775	0	12	14
A-C	-34.5473	9.4024	-101.291	-126.436	43	4	1	3814	0	14	14
A-I	-15.0423	42.2201	-36.2867	-9.1089	29	1	0	1556	0	12	14
B-C	-31.1235	-6.7718	-95.2708	-133.1661	43	6	1	3738	1	12	14
B-E	0.0	6.3052	-0.1331	6.1721	7	0	0	66	0	6	8
B-F	0.0	0.0	-0.0018	-0.0018	2	0	0	2	0	0	0
B-G	0.0	2.4616	-5.2084	-2.7468	10	0	0	186	0	2	6
B-H	-23.2869	1.2475	-102.056	-124.0954	49	6	1	4035	2	15	13
B-I	0.0	7.1864	-5.5036	1.6827	16	0	0	333	0	8	7
B-K	-3.0467	-19.0852	-27.7067	-49.8386	25	3	0	1191	1	11	11
B-L	-11.6797	0.8105	-16.6868	-27.5559	24	1	0	750	1	9	10
C-K	-21.5719	-25.0578	-84.7867	-131.4164	41	1	0	3452	6	24	30
D-E	-36.0251	7.4254	-98.528	-127.1277	42	5	1	3771	0	9	10
D-F	-31.4255	1.1028	-85.3282	-115.6509	41	7	1	3666	0	10	10
E-F	-27.6615	3.2479	-90.9739	-115.3875	42	4	1	3535	0	9	10
E-G	0.0	-20.9705	-21.7933	-42.7638	27	0	0	1224	0	10	9
E-H	0.0	0.0	-0.0631	-0.0631	3	0	0	6	0	1	1
E-I	-35.9144	3.2911	-97.2353	-129.8585	47	6	1	3659	2	15	15
E-J	0.0	0.0	-0.0537	-0.0537	2	0	0	15	0	0	3
F-G	-15.0902	-0.0031	-78.2565	-93.3497	43	2	0	3477	4	23	27
F-L	-21.3072	2.1185	-92.0876	-111.2763	46	6	1	3801	2	15	14
G-H	-22.1102	156.396	-112.857	21.4288	56	7	3	5092	6	28	34
H-I	0.0	0.0	-0.0256	-0.0256	3	0	0	13	0	1	2
I-J	-21.7018	141.3897	-106.738	12.9499	53	4	3	4756	6	28	32
K-L	0.0	11.6851	-18.1956	-6.5105	23	0	0	1042	0	15	14

Interface residues

• A-B: ALA372A, ARG371A, ARG394B, ARG408A, ARG408B, ASN406A, ASP350B, ASP400B, ASP413B, ASP428A, ASP428B, GLN397B, GLU375A, GLU376A, GLU405A, GLU410B, GLY393A, GLY399B, ILE401A, ILE401B, ILE412B, ILE427A, ILE427B, LEU370A, LEU391A, LEU392A, LEU392B, LEU395B, LEU423B, LYS378A, PHE403A, PHE403B, PRO374A, PRO396B, THR398B, THR402A, THR402B, THR425B, TRP390A, TRP404A, TRP407A, TYR381A, VAL373A, VAL380A, VAL411B
• A-C: ALA372C, ARG371C, ARG394A, ARG408A, ARG408C, ASN406C, ASP350A, ASP400A, ASP428C, GLN397A, GLU375C, GLU376C, GLU405C, GLU410A, GLY393C, GLY399A, ILE401A, ILE401C, ILE412A, ILE427A, ILE427C, LEU370C, LEU391C, LEU392A, LEU392C, LEU395A, LEU423A, LYS378C, PHE403A, PHE403C, PRO374C, PRO396A, THR398A, THR402A, THR402C, THR425A, TRP390C, TRP404C, TRP407C, TYR381C, VAL373C, VAL380C, VAL411A
• A-I: ALA372A, ALA372I, ARG348I, ARG371A, ARG371I, ASN406A, ASP366A, ASP366I, GLN347I, GLU363I, GLU376A, GLU377A, GLU405A, GLU405I, GLY351I, GLY369A, GLY369I, LEU368I, LEU370A, LEU370I, LYS365A, LYS365I, LYS426I, PRO362A, PRO362I, THR367A, THR367I, TRP353I, TRP407I
• B-C: ALA372B, ARG371B, ARG394C, ARG408B, ARG408C, ASN406B, ASP350C, ASP400C, ASP428B, GLN397C, GLU375B, GLU376B, GLU405B, GLU410C, GLY393B, GLY399C, ILE401B, ILE401C, ILE412C, ILE427B, ILE427C, LEU370B, LEU391B, LEU392B, LEU392C, LEU395C, LEU423C, LYS378B, PHE403B, PHE403C, PRO374B, PRO396C, THR398C, THR402B, THR402C, THR425C, TRP390B, TRP404B, TRP407B, TYR381B, VAL373B, VAL380B, VAL411C
• B-E: ASN344B, ASP420B, GLU377E, LEU354B, LYS378E, LYS421B, VAL346B
• B-F: ASN344B, SER416F
• B-G: ALA360B, ARG348G, ASN344B, ASP350G, ASP356B, GLU349G, GLU363B, ILE359B, LEU358B, SER343B
• B-H: ALA360B, ARG371H, ARG394H, ARG408H, ARG418B, ASN406H, ASP400H, ASP415B, ASP420B, ASP428H, GLN397H, GLU375H, GLU377B, GLU405H, GLU410H, GLY357B, GLY379B, GLY386B, GLY393H, GLY399H, HIS382B, ILE359B, ILE388H, ILE401H, ILE427H, LEU358B, LEU391H, LEU392H, LEU395B, LEU395H, LEU409H, LYS378B, LYS417B, PHE403H, PRO362B, PRO374H, PRO396H, SER343B, SER385B, SER416B, THR383B, THR402H, TRP390H, TRP404H, TRP407H, TYR381B, VAL361B, VAL380B, VAL380H
• B-I: ARG348B, ARG371I, ASN406I, ASP413B, ASP415B, ASP420B, ASP428I, GLU410B, GLY399B, ILE412B, LEU354B, LEU423B, LYS421B, LYS426I, THR398B, VAL411B
• B-K: ALA345K, ALA360K, ALA372B, ARG371B, ASN344K, ASN406B, ASP366K, GLN347K, GLU363K, GLU405B, GLY369B, GLY369K, ILE359K, LEU355K, LEU364K, LEU368K, LEU370B, LYS365B, LYS365K, LYS426B, PRO362K, SER343K, THR367K, TRP353K, VAL346K
• B-L: ALA345B, ARG348B, ASN344B, ASP350B, ASP366B, GLN347B, GLU349B, GLU363B, GLU375L, GLY351B, GLY369B, GLY379L, GLY393L, LEU395L, LYS365B, LYS378L, LYS417L, PRO362B, SER352B, THR367B, TRP353B, TRP390L, TYR381L, VAL380L
• C-K: ALA345C, ALA372K, ARG348C, ARG371K, ASN406K, ASP350C, ASP366K, ASP413C, ASP415C, ASP420C, GLN347C, GLN347K, GLU349C, GLU363K, GLU376K, GLU405K, GLU410C, GLY351C, GLY351K, GLY369K, ILE412C, LEU354C, LEU364K, LEU368K, LEU370K, LEU423C, LYS365K, LYS421C, LYS426K, PRO362K, SER352C, THR367K, THR398C, TRP353C, TRP353K, TRP407K, VAL346C, VAL361K, VAL373K, VAL411C, VAL422C
• D-E: ALA372D, ARG371D, ARG394E, ARG408D, ARG408E, ASN406D, ASP400E, GLN397E, GLU375D, GLU376D, GLU405D, GLU410E, GLY393D, GLY399E, ILE401D, ILE401E, ILE412E, ILE427D, ILE427E, LEU370D, LEU391D, LEU392D, LEU392E, LEU395E, LEU423E, LYS378D, LYS426D, PHE403D, PHE403E, PRO374D, PRO396E, THR398E, THR402D, THR402E, THR425E, TRP390D, TRP404D, TRP407D, TYR381D, VAL373D, VAL380D, VAL411E
• D-F: ALA372F, ARG371F, ARG394D, ARG408D, ARG408F, ASN406F, ASP400D, GLN397D, GLU375F, GLU376F, GLU405F, GLU410D, GLY393F, GLY399D, ILE401D, ILE401F, ILE412D, ILE427D, ILE427F, LEU370F, LEU391F, LEU392D, LEU392F, LEU395D, LEU423D, LYS378F, PHE403D, PHE403F, PRO374F, PRO396D, THR398D, THR402D, THR402F, THR425D, TRP390F, TRP404F, TRP407F, TYR381F, VAL373F, VAL380F, VAL411D
• E-F: ALA372E, ARG371E, ARG394F, ARG408E, ARG408F, ASN406E, ASP400F, GLN397F, GLU375E, GLU376E, GLU405E, GLU410F, GLY393E, GLY399F, ILE401E, ILE401F, ILE412F, ILE427E, ILE427F, LEU370E, LEU391E, LEU392E, LEU392F, LEU395F, LEU423F, LYS378E, LYS426E, PHE403E, PHE403F, PRO374E, PRO396F, THR398F, THR402E, THR402F, THR425F, TRP390E, TRP404E, TRP407E, TYR381E, VAL373E, VAL380E, VAL411F
• E-G: ALA345G, ALA360G, ALA372E, ARG371E, ASN344G, ASN406E, ASP366E, ASP366G, GLN347G, GLU363G, GLU405E, GLY369E, GLY369G, ILE359G, LEU355G, LEU364G, LEU368G, LEU370E, LYS365E, LYS365G, LYS426E, PRO362G, SER343G, THR367G, TRP353G, VAL346G, VAL361G
• E-H: ARG394H, GLN397H, GLU377E
• E-I: ALA360E, ARG394I, ARG408I, ARG418E, ASN406I, ASP400I, ASP415E, ASP420E, ASP428I, GLN397I, GLU375I, GLU377E, GLU405I, GLY379E, GLY386E, GLY393I, GLY399I, HIS382E, ILE359E, ILE388I, ILE401I, ILE427I, LEU358E, LEU391I, LEU392I, LEU395E, LEU395I, LEU409I, LYS378E, LYS417E, LYS426I, PHE403I, PRO362E, PRO374I, PRO396I, SER343E, SER385E, SER416E, THR383E, THR402I, TRP390I, TRP404I, TRP407I, TYR381E, VAL361E, VAL380E, VAL380I
• E-J: GLU349J, SER343E
• F-G: ALA345F, ALA372G, ARG348F, ARG371G, ARG408F, ASN406G, ASP350F, ASP366G, ASP413F, ASP415F, ASP420F, GLN347F, GLN347G, GLU349F, GLU363G, GLU376G, GLU377G, GLU405G, GLU410F, GLY351F, GLY351G, GLY369G, ILE412F, LEU354F, LEU364G, LEU368G, LEU370G, LEU423F, LYS365G, LYS421F, LYS426G, PRO362G, SER352F, THR367G, THR398F, TRP353F, TRP353G, TRP407G, VAL346F, VAL361G, VAL373G, VAL411F, VAL422F
• F-L: ALA360F, ARG371L, ARG394L, ARG408L, ARG418F, ASN406L, ASP400L, ASP415F, ASP428L, GLN397L, GLU375L, GLU377F, GLU405L, GLY357F, GLY379F, GLY386F, GLY393L, GLY399L, HIS382F, ILE359F, ILE388L, ILE401L, ILE427L, LEU358F, LEU391L, LEU392L, LEU395F, LEU395L, LEU409L, LYS378F, LYS417F, PHE403L, PRO362F, PRO374L, PRO396L, SER343F, SER385F, SER416F, THR383F, THR402L, TRP390L, TRP404L, TRP407L, TYR381F, VAL361F, VAL380F
• G-H: ALA345G, ALA345H, ARG348G, ARG348H, ARG408G, ARG408H, ASN344G, ASN344H, ASP350G, ASP350H, ASP356G, ASP356H, ASP400G, ASP400H, ASP413G, ASP413H, ASP415G, ASP415H, ASP420G, ASP420H, GLN347G, GLN347H, GLN397G, GLN397H, GLU349G, GLU349H, GLU410G, GLU410H, GLY357G, GLY357H, GLY399G, GLY399H, ILE401G, ILE401H, ILE412G, ILE412H, LEU354G, LEU354H, LEU355G, LEU355H, LEU423G, LEU423H, LYS421G, LYS421H, SER352G, SER352H, THR398G, THR398H, THR425G, THR425H, VAL346G, VAL346H, VAL411G, VAL411H, VAL422G, VAL422H
• H-I: ARG394H, ASP428I, GLN397H
• I-J: ALA345I, ARG348I, ARG348J, ARG408I, ARG408J, ASN344I, ASP350I, ASP350J, ASP356I, ASP356J, ASP400J, ASP413I, ASP413J, ASP415I, ASP415J, ASP420I, ASP420J, GLN347I, GLN347J, GLN397J, GLU349I, GLU349J, GLU410I, GLU410J, GLY357I, GLY357J, GLY399I, GLY399J, ILE401I, ILE401J, ILE412I, ILE412J, LEU354I, LEU354J, LEU355I, LEU355J, LEU423I, LEU423J, LYS421I, LYS421J, SER343I, SER352I, SER352J, THR398I, THR398J, THR425I, THR425J, VAL346I, VAL346J, VAL411I, VAL411J, VAL422I, VAL422J
• K-L: ALA360K, ARG418K, ARG418L, ASN344K, ASN344L, ASP356K, ASP356L, ASP415K, ASP415L, ASP420K, ASP420L, HIS382K, HIS382L, LEU358K, LEU358L, LYS417K, LYS417L, SER343K, SER343L, SER416K, SER416L, THR383K, THR383L