2PKG

structure of a complex between the a subunit of protein phosphatase 2a and the small t antigen of sv40

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: B-C
  • Int. Res.: 38
  • Norm. En. per Res.: -3.143
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-37.361	-132.9804	-67.3327	-237.674	90	5	8	4143	8	51	56
A-C	0.0	2.8756	-116.144	-113.2684	52	5	0	4365	0	14	14
A-D	-22.636	-10.6724	-54.8802	-88.1887	32	3	0	2404	4	16	15
B-C	-35.9493	-13.7659	-69.7205	-119.4357	38	10	0	3179	4	16	17
B-D	-19.7826	-0.3196	-102.095	-122.1972	50	7	1	4146	2	15	14

Interface residues

• A-B: ALA422A, ALA422B, ALA457A, ALA457B, ALA461A, ALA461B, ALA462A, ALA462B, ARG398A, ARG418A, ARG418B, ARG420A, ARG420B, ARG459A, ARG459B, ASN383A, CYS377A, CYS377B, GLN339A, GLN339B, GLN402A, GLU110B, GLU269A, GLU269B, GLU297A, GLU297B, GLU308A, GLU308B, GLU311A, GLU311B, GLU379A, GLU379B, GLU393A, GLU393B, GLU425A, GLU425B, GLU437A, GLU460A, GLU460B, GLU471A, GLU471B, GLU71B, HIS304A, HIS304B, HIS340A, HIS340B, HIS454A, ILE424A, ILE424B, ILE458A, ILE458B, LEU382A, LEU382B, LEU421A, LEU421B, LEU429A, LEU429B, LYS107B, LYS272B, LYS305A, LYS305B, LYS307A, LYS307B, LYS416A, LYS416B, LYS467A, LYS467B, LYS468A, LYS468B, LYS472A, LYS472B, LYS546B, PRO354A, PRO378B, PRO428A, PRO428B, SER343A, SER343B, SER464A, SER464B, THR268A, TRP417A, TRP417B, TYR456A, TYR456B, VAL103B, VAL455A, VAL455B, VAL511A, VAL511B
• A-C: ARG105A, ARG129C, ARG144A, ARG145C, ARG182A, ARG183A, ARG258A, ASP131C, ASP139A, ASP151C, ASP176A, ASP177A, ASP218A, CYS143C, CYS153C, GLN217A, GLU100A, GLU101A, GLU216A, GLY149C, GLY155C, HIS122C, LEU133C, LEU150C, LEU159C, LEU222A, LEU223A, LYS126C, LYS130C, MET146C, MET180A, PHE141A, PHE144C, PHE148C, PRO132C, PRO179A, SER143A, SER219A, THR102A, THR142A, THR156C, THR178A, THR98A, TRP135C, TRP140A, TRP147C, TRP257A, VAL134C, VAL136C, VAL181A, VAL220A, VAL99A
• A-D: ALA104D, ALA478A, ALA480A, ASP151D, ASP440A, ASP515A, CYS103D, CYS153D, GLN99D, GLU102D, GLU154D, GLU476A, GLY155D, GLY474A, GLY513A, HIS479A, HIS520A, ILE516A, LEU152D, LEU158D, LYS105D, LYS475A, LYS519A, LYS98D, MET107D, PHE473A, PRO101D, THR481A, TRP100D, TRP477A, VAL436A, VAL92D
• B-C: ALA104C, ALA109C, ALA478B, ALA480B, ARG145C, ASP151C, ASP515B, CYS103C, CYS153C, CYS512B, CYS97C, GLN514B, GLN99C, GLU102C, GLU154C, GLU476B, GLY155C, GLY474B, GLY513B, HIS479B, HIS520B, ILE483B, ILE516B, LEU152C, LEU157C, LEU158C, LYS105C, LYS475B, LYS519B, LYS98C, MET107C, PRO101C, SER108C, THR517B, THR518B, TRP100C, TRP477B, VAL92C
• B-D: ARG105B, ARG129D, ARG144B, ARG145D, ARG182B, ARG183B, ARG258B, ASP131D, ASP139B, ASP151D, ASP176B, ASP177B, ASP218B, CYS143D, CYS153D, GLN217B, GLU100B, GLU101B, GLU216B, GLY149D, GLY155D, HIS122D, LEU133D, LEU150D, LEU159D, LEU222B, LYS126D, LYS130D, MET146D, MET180B, PHE141B, PHE144D, PHE148D, PRO132D, PRO179B, SER143B, SER219B, THR102B, THR142B, THR156D, THR178B, THR98B, TRP135D, TRP140B, TRP147D, TRP257B, VAL134D, VAL136D, VAL220B, VAL99B