2PI2

full-length replication protein a subunits rpa14 and rpa32

• Total interactions analyzed: 28
• Total true interactions: 13
• Strongest Interaction:
  • Chains: D-H
  • Int. Res.: 109
  • Norm. En. per Res.: -4.6888
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	12.5996	-28.9174	-16.3178	43	0	2	1557	0	11	5
A-E	-61.8332	-65.481	-372.948	-500.2621	113	12	13	15069	4	24	25
A-F	-11.8715	-23.9789	-63.0345	-98.8849	39	1	2	2659	1	12	6
A-H	0.0	0.0	-0.0006	-0.0006	2	0	0	2	0	0	0
B-C	0.0	0.0	-0.1179	-0.1179	2	0	0	16	0	0	0
B-E	-14.5228	-22.7993	-65.6779	-102.9999	34	1	2	2709	1	12	8
B-F	-70.8598	-61.1217	-391.325	-523.3064	118	17	13	15471	5	25	29
C-D	0.0	0.0	-0.0349	-0.0349	5	0	0	25	0	0	1
C-E	0.0	0.0	-0.1624	-0.1624	5	0	0	17	0	4	4
C-G	-80.2791	-57.8761	-380.912	-519.0672	115	12	13	15304	4	22	24
D-E	0.0	0.0	-0.0733	-0.0733	2	0	1	24	0	0	1
D-H	-66.5342	-65.2739	-379.273	-511.0811	109	15	13	14860	5	23	26
E-H	-20.6005	-57.1039	-69.0353	-146.7397	37	1	2	2916	8	15	14

Interface residues

• A-B: ALA165A, ALA165B, ALA172A, ALA172B, ALA43A, ALA43B, ARG42A, ARG42B, ASN153A, ASN153B, ASN164A, ASN164B, ASP151A, ASP151B, GLN44A, GLN44B, GLU154A, GLU154B, GLU161A, GLU161B, HIS45A, HIS45B, ILE159B, ILE163A, ILE163B, ILE46A, ILE46B, LEU160A, LEU160B, LEU169A, LEU169B, MET152B, MET167A, MET167B, PRO48A, PRO48B, THR156A, THR156B, THR157A, THR157B, VAL162B, VAL168A, VAL168B
• A-E: ALA100A, ALA102E, ALA165A, ALA57A, ALA99A, ARG11E, ARG81A, ARG9E, ASN100E, ASN153A, ASN164A, ASN68A, ASP108E, ASP151A, ASP6E, ASP90E, ASP95A, ASP95E, ASP96A, CYS26E, CYS49A, GLN111E, GLN53A, GLN86E, GLU101E, GLU123A, GLU150A, GLU154A, GLU161A, GLU68E, GLU89E, GLY116E, GLY67A, GLY78A, GLY97E, HIS107E, HIS158A, HIS166A, HIS92E, ILE105E, ILE106E, ILE117E, ILE159A, ILE163A, ILE51A, ILE66A, ILE66E, ILE79A, ILE80A, ILE94A, LEU115E, LEU149A, LEU160A, LEU169A, LEU54A, LEU55A, LEU7E, LEU96E, LEU98E, LYS104E, LYS139A, LYS171A, LYS88E, LYS93A, MET102A, MET152A, MET167A, MET4E, MET5E, MET97A, PHE109E, PHE112E, PHE155A, PHE27E, PHE87E, PHE94E, PRO101A, PRO110E, PRO114E, PRO122A, PRO148A, PRO24E, PRO48A, PRO8E, PRO93E, SER10E, SER170A, SER52A, SER56A, SER83E, SER91E, THR124A, THR156A, THR157A, THR50A, THR58A, THR82E, THR98A, TYR113E, TYR125A, TYR84E, TYR99E, VAL103E, VAL118E, VAL162A, VAL168A, VAL25E, VAL28E, VAL69A, VAL69E, VAL70E, VAL77A, VAL85E
• A-F: ALA102F, ALA165A, ALA172A, ALA41A, ALA43A, ARG30F, ARG42A, ASN100F, ASN164A, ASN173A, ASP108F, ASP95F, GLN175A, GLN44A, GLN73A, GLU101F, GLU47F, GLU89F, GLY46F, GLY97F, HIS45A, HIS92F, ILE105F, ILE46A, ILE66F, LEU169A, LEU96F, LEU98F, LYS104F, LYS171A, MET167A, PHE109F, PHE94F, PRO93F, SER170A, SER174A, TYR99F, VAL168A, VAL47A
• A-H: ALA100A, ALA75H
• B-C: PRO87C, SER174B
• B-E: ALA102E, ALA165B, ALA172B, ALA43B, ARG30E, ARG42B, ASN100E, ASN164B, ASN173B, ASP108E, ASP95E, GLN44B, GLU101E, GLU89E, GLY46E, GLY97E, HIS45B, HIS92E, ILE105E, ILE46B, LEU169B, LEU96E, LEU98E, LYS104E, LYS171B, MET167B, PHE109E, PHE94E, PRO93E, SER170B, SER174B, TYR99E, VAL168B, VAL47B
• B-F: ALA100B, ALA102F, ALA165B, ALA57B, ALA99B, ARG11F, ARG81B, ARG9F, ASN100F, ASN153B, ASN164B, ASN68B, ASP103B, ASP108F, ASP151B, ASP6F, ASP90F, ASP95B, ASP95F, ASP96B, CYS26F, CYS49B, GLN111F, GLN119F, GLN53B, GLN86F, GLU101F, GLU123B, GLU150B, GLU154B, GLU161B, GLU68F, GLU89F, GLY116F, GLY67B, GLY71F, GLY78B, GLY97F, HIS107F, HIS120F, HIS158B, HIS166B, HIS92F, ILE105F, ILE106F, ILE117F, ILE159B, ILE163B, ILE51B, ILE66B, ILE66F, ILE79B, ILE80B, ILE94B, LEU115F, LEU149B, LEU160B, LEU169B, LEU54B, LEU55B, LEU7F, LEU96F, LEU98F, LYS104F, LYS138B, LYS139B, LYS171B, LYS88F, LYS93B, MET102B, MET152B, MET167B, MET4F, MET5F, MET97B, PHE109F, PHE112F, PHE155B, PHE27F, PHE87F, PHE94F, PRO101B, PRO110F, PRO114F, PRO122B, PRO148B, PRO24F, PRO48B, PRO8F, PRO93F, SER10F, SER170B, SER52B, SER56B, SER83F, SER91F, THR124B, THR156B, THR157B, THR50B, THR82F, THR98B, TYR113F, TYR125B, TYR84F, TYR99F, VAL103F, VAL118F, VAL162B, VAL168B, VAL25F, VAL28F, VAL2F, VAL69B, VAL69F, VAL70F, VAL77B, VAL85F
• C-D: ASN137D, ASP61C, GLN136C, GLN136D, GLU62C
• C-E: GLU47E, GLU84C, GLY48E, LYS49E, PRO87C
• C-G: ALA100C, ALA102G, ALA165C, ALA57C, ALA99C, ARG11G, ARG81C, ARG9G, ASN100G, ASN153C, ASN164C, ASN68C, ASP108G, ASP151C, ASP3G, ASP6G, ASP90G, ASP95C, ASP95G, ASP96C, CYS26G, CYS49C, GLN111G, GLN119G, GLN53C, GLN86G, GLU101G, GLU123C, GLU150C, GLU154C, GLU161C, GLU68G, GLU89G, GLY116G, GLY67C, GLY78C, GLY97G, HIS107G, HIS158C, HIS166C, HIS82C, HIS92G, ILE105G, ILE106G, ILE117G, ILE159C, ILE163C, ILE51C, ILE66C, ILE66G, ILE79C, ILE80C, ILE94C, LEU115G, LEU149C, LEU160C, LEU169C, LEU54C, LEU55C, LEU7G, LEU96G, LEU98G, LYS104G, LYS139C, LYS171C, LYS88G, LYS93C, MET102C, MET152C, MET167C, MET4G, MET5G, MET97C, PHE109G, PHE112G, PHE155C, PHE27G, PHE87G, PHE94G, PRO101C, PRO110G, PRO114G, PRO121C, PRO122C, PRO148C, PRO24G, PRO48C, PRO8G, PRO93G, SER10G, SER170C, SER52C, SER56C, SER83G, SER91G, THR124C, THR156C, THR157C, THR50C, THR98C, TYR113G, TYR125C, TYR84G, TYR99G, VAL103G, VAL118G, VAL162C, VAL168C, VAL25G, VAL28G, VAL69C, VAL69G, VAL70G, VAL77C, VAL85G
• D-E: ALA100D, ALA75E
• D-H: ALA100D, ALA102H, ALA165D, ALA57D, ALA99D, ARG11H, ARG81D, ARG9H, ASN100H, ASN153D, ASN164D, ASN68D, ASP108H, ASP151D, ASP3H, ASP6H, ASP90H, ASP95D, ASP95H, ASP96D, CYS26H, CYS49D, GLN111H, GLN53D, GLN86H, GLU101H, GLU123D, GLU150D, GLU154D, GLU161D, GLU68H, GLU89H, GLY116H, GLY67D, GLY78D, GLY97H, HIS107H, HIS158D, HIS166D, HIS92H, ILE105H, ILE106H, ILE117H, ILE159D, ILE163D, ILE51D, ILE66D, ILE66H, ILE79D, ILE94D, LEU115H, LEU149D, LEU160D, LEU169D, LEU54D, LEU55D, LEU7H, LEU96H, LEU98H, LYS104H, LYS139D, LYS171D, LYS88H, LYS93D, MET152D, MET167D, MET4H, MET5H, MET97D, PHE109H, PHE112H, PHE155D, PHE27H, PHE87H, PHE94H, PRO101D, PRO110H, PRO114H, PRO24H, PRO48D, PRO8H, PRO93H, SER10H, SER170D, SER52D, SER56D, SER83H, SER91H, THR124D, THR156D, THR157D, THR50D, THR58D, THR98D, TYR113H, TYR125D, TYR84H, TYR99H, VAL103H, VAL118H, VAL162D, VAL168D, VAL25H, VAL28H, VAL69D, VAL69H, VAL70H, VAL77D, VAL85H
• E-H: ALA75E, ALA75H, ALA77E, ARG72E, ARG72H, ASP22E, ASP22H, ASP3E, ASP3H, ASP6E, ASP6H, ILE21E, ILE21H, LEU7E, LEU7H, LEU80E, LEU80H, LYS23E, LYS23H, LYS76E, LYS76H, MET4E, MET4H, MET56E, MET56H, MET5H, PRO24E, PRO24H, PRO8E, PRO8H, THR74E, THR74H, THR82H, VAL2E, VAL2H, VAL73E, VAL73H