2PBJ

gsh-heme bound microsomal prostaglandin e synthase

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 117
  • Norm. En. per Res.: -2.492
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	0.0	-23.5511	-264.554	-288.1051	119	39	0	12820	0	50	55
A-D	-17.6629	20.7848	-57.7352	-54.6133	48	16	0	2917	0	21	19
B-C	0.0	17.0141	-52.5594	-35.5453	48	15	0	2920	0	22	19
B-D	0.0	-25.9964	-23.1894	-49.1858	23	0	0	1319	0	13	22
C-D	0.0	-21.851	-269.715	-291.566	117	38	0	12709	0	50	55

Interface residues

• A-B: ALA191A, ALA191B, ALA194A, ALA194B, ALA227B, ALA238A, ALA238B, ARG228A, ARG228B, ARG296A, ARG296B, ARG298A, ARG298B, ASN196A, ASN196B, ASN207A, ASN207B, ASN214A, ASN214B, ASP197A, ASP197B, ASP239A, ASP239B, ASP240A, ASP240B, GLN180A, GLN180B, GLN198A, GLN198B, GLN236A, GLN236B, GLU183A, GLU184A, GLU184B, GLU201A, GLU201B, GLU204A, GLU204B, GLU215A, GLU215B, GLU217A, GLU217B, GLU226A, GLU226B, GLU230A, GLU230B, GLY199A, GLY199B, GLY206A, GLY206B, GLY224B, HIS244A, HIS244B, HIS297A, HIS297B, ILE185A, ILE185B, ILE186A, ILE186B, LEU211A, LEU211B, LEU213A, LEU213B, LEU242A, LEU242B, LEU293A, LEU293B, LEU299A, LEU299B, LYS193A, LYS193B, LYS200A, LYS200B, LYS208A, LYS208B, LYS216A, LYS216B, LYS225A, LYS225B, LYS233A, LYS233B, LYS313A, LYS313B, MET192A, MET192B, MET212A, MET212B, MET232A, MET232B, PHE205A, PHE205B, PRO181A, PRO190A, PRO190B, SER295A, SER295B, THR187A, THR187B, THR203A, THR203B, THR229A, THR229B, TRP210A, TRP210B, TRP237A, TRP237B, TRP241A, TRP241B, TYR188A, TYR188B, TYR189A, TYR189B, TYR209A, TYR209B, VAL195A, VAL195B, VAL202A, VAL202B, VAL243B
• A-D: ALA138A, ALA257D, ALA259D, ALA283D, ALA284D, ARG137A, ARG146A, ARG252D, ARG304D, ASN133A, ASN302D, ASP301D, ASP348D, GLN198A, GLN300D, GLU139A, GLU201A, GLU256D, GLU274A, GLY199A, ILE140A, LEU136A, LEU258D, LEU288D, LEU299D, LYS141A, LYS193A, LYS200A, LYS291D, LYS294D, MET281A, MET281D, PHE142A, PRO134A, PRO254D, SER143A, SER144A, SER295D, THR203A, THR253D, THR255D, TYR145A, TYR280D, TYR287D, VAL135A, VAL195A, VAL202A, VAL273A
• B-C: ALA138C, ALA257B, ALA259B, ALA283B, ALA284B, ARG137C, ARG146C, ARG252B, ARG304B, ASN133C, ASN302B, ASP301B, ASP348B, GLN198C, GLN300B, GLU139C, GLU201C, GLU256B, GLU274C, GLY199C, ILE140C, LEU136C, LEU258B, LEU288B, LEU299B, LYS141C, LYS193C, LYS200C, LYS291B, LYS294B, MET281B, MET281C, PHE142C, PRO134C, PRO254B, SER143C, SER144C, SER295B, THR203C, THR253B, THR255B, TYR145C, TYR280B, TYR287B, VAL135C, VAL195C, VAL202C, VAL273C
• B-D: ARG296D, ARG298B, ARG298D, ASN302B, ASN302D, ASP301B, ASP301D, ASP306B, ASP306D, GLN300B, GLN300D, HIS297B, HIS297D, LEU299B, LEU299D, LYS291B, LYS291D, LYS294B, LYS294D, SER295B, SER295D, VAL303B, VAL303D
• C-D: ALA191C, ALA191D, ALA194C, ALA194D, ALA238C, ALA238D, ARG228C, ARG228D, ARG296C, ARG296D, ARG298C, ARG298D, ASN196C, ASN196D, ASN207C, ASN207D, ASN214C, ASN214D, ASP197C, ASP197D, ASP239C, ASP239D, ASP240C, ASP240D, GLN180C, GLN180D, GLN198C, GLN198D, GLN236C, GLN236D, GLU183C, GLU184C, GLU184D, GLU201C, GLU201D, GLU204C, GLU204D, GLU215C, GLU215D, GLU217C, GLU217D, GLU226C, GLU226D, GLU230C, GLU230D, GLY199C, GLY199D, GLY206C, GLY206D, GLY224D, HIS244C, HIS244D, HIS297C, HIS297D, ILE185C, ILE185D, ILE186C, ILE186D, LEU211C, LEU211D, LEU213C, LEU213D, LEU242C, LEU242D, LEU293C, LEU293D, LEU299C, LEU299D, LYS193C, LYS193D, LYS200C, LYS200D, LYS208C, LYS208D, LYS216C, LYS216D, LYS225C, LYS225D, LYS233C, LYS233D, LYS313C, LYS313D, MET192C, MET192D, MET212C, MET212D, MET232C, MET232D, PHE205C, PHE205D, PRO190C, PRO190D, SER295C, SER295D, THR187C, THR187D, THR203C, THR203D, THR229C, THR229D, TRP210C, TRP210D, TRP237C, TRP237D, TRP241C, TRP241D, TYR188C, TYR188D, TYR189C, TYR189D, TYR209C, TYR209D, VAL195C, VAL195D, VAL202C, VAL202D, VAL243D