2P63

suprafacial orientation of the scfcdc4 dimer accommodates multiple geometries for substrate ubiquitination

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 101
  • Norm. En. per Res.: -5.2754
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-40.7751	-55.1026	-342.951	-438.8288	100	32	22	16062	2	30	12
A-C	0.0	0.0	-0.2263	-0.2263	6	0	0	47	0	0	1
A-D	0.0	0.0	-4.1814	-4.1814	13	0	0	278	0	4	2
B-C	0.0	-2.4553	-1.5779	-4.0332	14	2	0	346	0	5	2
B-D	-50.597	17.9019	-115.997	-148.6921	47	18	2	4034	3	14	18
C-D	-80.8978	-88.4796	-363.443	-532.8203	101	30	18	16425	5	28	9

Interface residues

• A-B: ALA233A, ALA233B, ALA241A, ALA241B, ALA252A, ALA252B, ARG249A, ARG249B, ARG256A, ARG256B, ARG272A, ARG272B, ASN235A, ASN235B, ASN236A, ASN236B, ASN237A, ASN237B, ASN245A, ASN245B, ASN253A, ASN253B, ASN269A, ASN269B, ASP228A, ASP228B, ASP255A, ASP255B, ASP261A, ASP261B, ASP268A, ASP268B, GLU224A, GLU224B, GLU229A, GLU229B, GLU258A, GLU258B, GLY263A, GLY263B, HIS240A, HIS240B, ILE230A, ILE230B, ILE234A, ILE234B, ILE266A, ILE266B, LEU226A, LEU226B, LEU238A, LEU238B, LEU246A, LEU246B, LEU247A, LEU247B, LEU250A, LEU250B, LEU259A, LEU259B, LEU262A, LEU262B, LEU265A, LEU265B, LEU270A, LEU270B, LYS244A, LYS244B, LYS267A, LYS267B, LYS271A, LYS271B, PHE231A, PHE231B, PHE243A, PHE243B, PHE248A, PHE248B, PRO223A, PRO223B, PRO239A, PRO239B, SER222A, SER222B, SER227A, SER227B, SER232A, SER232B, SER257A, SER257B, SER260A, SER260B, THR264A, THR264B, TYR225A, TYR225B, TYR242A, TYR242B, VAL251A, VAL251B
• A-C: ALA252C, LYS244A, LYS244C, PHE248A, PHE248C, VAL251C
• A-D: ARG249A, ARG272D, ASN245A, ASN253A, ASN269D, ASP268D, HIS240A, LEU265D, LYS244A, PHE243A, PHE248A, PRO223D, TYR225D
• B-C: ALA252C, ARG249C, ARG272B, ASN245C, ASN253C, ASN269B, ASP261B, ASP268B, GLU224B, LEU265B, LYS244C, PHE248C, THR264B, TYR225B
• B-D: ARG272B, ARG272D, ASN269B, ASN269D, ASP228B, ASP228D, ASP261B, ASP261D, ASP268B, ASP268D, GLU224B, GLU224D, GLU229B, GLU229D, GLU258B, GLU258D, GLY263B, GLY263D, ILE230B, ILE230D, ILE266B, ILE266D, LEU226B, LEU226D, LEU262B, LEU262D, LEU265B, LEU265D, LYS267B, LYS267D, LYS271B, LYS271D, PHE231D, PRO223B, PRO223D, SER222B, SER227B, SER227D, SER232B, SER257B, SER257D, SER260B, SER260D, THR264B, THR264D, TYR225B, TYR225D
• C-D: ALA233C, ALA233D, ALA241C, ALA241D, ALA252C, ALA252D, ARG249C, ARG249D, ARG256C, ARG256D, ARG272C, ARG272D, ASN235C, ASN235D, ASN236C, ASN236D, ASN237C, ASN237D, ASN245C, ASN245D, ASN253C, ASN253D, ASN269C, ASN269D, ASP228C, ASP228D, ASP255C, ASP255D, ASP261C, ASP261D, ASP268C, ASP268D, ASP273C, ASP273D, GLU224C, GLU224D, GLU229C, GLU229D, GLU258C, GLU258D, GLY263C, GLY263D, HIS240C, HIS240D, ILE230C, ILE230D, ILE234C, ILE234D, ILE266C, ILE266D, LEU226C, LEU226D, LEU238C, LEU238D, LEU246C, LEU246D, LEU247C, LEU247D, LEU250C, LEU250D, LEU259C, LEU259D, LEU262C, LEU262D, LEU265C, LEU265D, LEU270C, LEU270D, LYS244C, LYS244D, LYS267C, LYS267D, LYS271C, LYS271D, PHE231C, PHE231D, PHE243C, PHE243D, PHE248C, PHE248D, PRO223C, PRO223D, PRO239C, PRO239D, SER222C, SER227C, SER227D, SER232C, SER232D, SER257C, SER257D, SER260C, SER260D, THR264C, THR264D, TYR225C, TYR225D, TYR242C, TYR242D, VAL251C, VAL251D