2OUI

d275p mutant of alcohol dehydrogenase from protozoa entamoeba histolytica

• Total interactions analyzed: 6
• Total true interactions: 6
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 170
  • Norm. En. per Res.: -5.8123
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-224.6474	-45.8324	-686.33	-956.8097	169	37	12	23655	2	64	62
A-C	-25.3342	16.1299	-153.24	-162.4443	75	7	0	6486	2	38	34
A-D	-73.8103	-57.7145	-228.134	-359.6589	107	15	5	10023	6	32	41
B-C	-68.3262	-55.2039	-228.154	-351.684	103	17	5	9835	6	33	41
B-D	-33.7428	-8.6444	-148.79	-191.1771	76	6	0	6415	2	38	35
C-D	-235.9002	-55.9713	-696.215	-988.0865	170	37	12	23807	3	64	62

Interface residues

• A-B: ALA250A, ALA250B, ALA46A, ALA46B, ALA48A, ALA48B, ARG278A, ARG278B, ARG97A, ARG97B, ASN114A, ASN114B, ASN163A, ASN163B, ASN264A, ASN264B, ASN266A, ASN266B, ASN273A, ASN273B, ASP168A, ASP168B, ASP237A, ASP237B, ASP245A, ASP245B, ASP261A, ASP261B, ASP272A, ASP272B, GLU160A, GLU160B, GLU270A, GLU270B, GLU280A, GLU280B, GLU93A, GLU93B, GLU94A, GLU94B, GLY104A, GLY104B, GLY105A, GLY105B, GLY108A, GLY108B, GLY259A, GLY259B, GLY263A, GLY263B, GLY269A, GLY269B, GLY271A, GLY271B, GLY282A, GLY282B, GLY284A, GLY284B, GLY286A, GLY286B, GLY292A, GLY292B, GLY293A, GLY293B, GLY47A, GLY47B, GLY50A, GLY50B, GLY98A, GLY98B, HIS102A, HIS102B, HIS157A, HIS157B, HIS247A, HIS247B, HIS287A, HIS287B, HIS289A, HIS289B, HIS291A, HIS291B, HIS42A, HIS42B, ILE241A, ILE241B, ILE256A, ILE256B, ILE262A, ILE262B, ILE274A, ILE274B, ILE276A, ILE276B, ILE290A, ILE290B, ILE49A, ILE49B, ILE86A, ILE86B, LEU107A, LEU107B, LEU161A, LEU161B, LEU268A, LEU268B, LEU294A, LEU294B, LYS165A, LYS165B, LYS234A, LYS234B, LYS238A, LYS238B, LYS254A, LYS254B, LYS257A, LYS257B, LYS288A, LYS288B, MET101A, MET101B, MET106A, MET106B, MET285A, MET285B, PHE249A, PHE249B, PRO100A, PRO100B, PRO258A, PRO258B, PRO275A, PRO275B, PRO277A, PRO277B, PRO296A, PRO296B, SER103A, SER103B, SER260A, SER260B, SER279A, SER279B, SER39A, SER39B, THR154A, THR154B, THR295A, THR295B, THR43B, TRP110A, TRP110B, TRP281A, TRP281B, TYR267A, TYR267B, TYR99A, TYR99B, VAL236A, VAL236B, VAL246A, VAL246B, VAL253A, VAL253B, VAL265A, VAL265B, VAL283A, VAL283B
• A-C: ALA129A, ALA129C, ALA131A, ALA131C, ARG299A, ARG299C, ARG301A, ARG301C, ARG74A, ARG74C, ARG97A, ARG97C, ASN132A, ASN132C, ASP130A, ASP130C, ASP26A, ASP26C, ASP89A, ASP89C, GLN96A, GLN96C, GLU128A, GLU128C, GLU303A, GLU303C, GLU92A, GLU92C, GLU93A, GLU93C, GLU94A, GLU94C, GLY104A, GLY104C, GLY23A, GLY23C, GLY297A, GLY297C, GLY298A, GLY298C, GLY91A, GLY91C, GLY98A, GLY98C, LEU133A, LEU133C, LEU25A, LEU25C, LEU71A, LEU71C, LYS304A, LYS304C, LYS73A, LYS73C, MET302A, MET302C, PRO100A, PRO100C, PRO24A, PRO24C, PRO296A, PRO296C, PRO84A, PRO84C, PRO88A, PRO88C, SER103A, SER70A, SER70C, SER95A, SER95C, TRP90A, TRP90C, VAL300A, VAL300C
• A-D: ALA159A, ALA159D, ALA184A, ALA184D, ALA186A, ALA186D, ALA191A, ALA191D, ALA207D, ALA212A, ALA212D, ALA306A, ALA306D, ARG193A, ARG193D, ARG299A, ARG299D, ARG301A, ARG301D, ARG74A, ARG74D, ASN187A, ASN187D, ASP168A, ASP168D, ASP214A, ASP214D, ASP237A, ASP237D, GLU160A, GLU160D, GLU303A, GLU303D, GLY155A, GLY155D, GLY167A, GLY167D, GLY185A, GLY185D, GLY190A, GLY190D, GLY192A, GLY192D, GLY211A, GLY211D, GLY312A, GLY312D, HIS157A, HIS157D, HIS188A, HIS188D, ILE164A, ILE164D, ILE194A, ILE194D, ILE309A, ILE309D, LEU166A, LEU166D, LEU189A, LEU189D, LEU208A, LEU208D, LEU305A, LEU305D, LEU308A, LEU308D, LEU314A, LEU314D, LYS165A, LYS165D, LYS234A, LYS234D, LYS238A, LYS238D, LYS257A, LYS257D, LYS304A, LYS304D, LYS313A, LYS313D, PHE156A, PHE156D, PRO296D, SER307A, SER307D, SER310A, SER310D, THR153A, THR153D, THR169A, THR169D, THR213A, THR213D, THR311A, THR311D, TYR210A, TYR210D, VAL152A, VAL152D, VAL170A, VAL170D, VAL183A, VAL183D, VAL236A, VAL300A, VAL300D
• B-C: ALA159B, ALA159C, ALA184B, ALA184C, ALA186B, ALA186C, ALA191B, ALA191C, ALA207B, ALA212B, ALA212C, ALA306B, ALA306C, ARG193B, ARG193C, ARG301B, ARG301C, ARG74B, ARG74C, ASN187B, ASN187C, ASP168B, ASP168C, ASP214B, ASP214C, ASP237B, ASP237C, GLU160B, GLU160C, GLU303B, GLU303C, GLY155B, GLY155C, GLY167B, GLY167C, GLY185B, GLY185C, GLY190B, GLY190C, GLY192B, GLY192C, GLY211B, GLY211C, GLY312B, GLY312C, HIS157B, HIS157C, HIS188B, HIS188C, ILE164B, ILE164C, ILE194B, ILE194C, ILE309B, ILE309C, LEU166B, LEU166C, LEU189B, LEU189C, LEU208B, LEU208C, LEU305B, LEU305C, LEU308B, LEU308C, LEU314B, LEU314C, LYS165B, LYS165C, LYS234B, LYS234C, LYS238B, LYS238C, LYS257B, LYS257C, LYS304B, LYS304C, LYS313B, LYS313C, PHE156B, PHE156C, SER307B, SER307C, SER310B, SER310C, THR153B, THR153C, THR169B, THR169C, THR213B, THR213C, THR311B, THR311C, TYR210B, TYR210C, VAL152B, VAL152C, VAL170B, VAL170C, VAL183B, VAL183C, VAL300B, VAL300C
• B-D: ALA129B, ALA129D, ALA131B, ALA131D, ARG299B, ARG299D, ARG301B, ARG301D, ARG74B, ARG74D, ARG97B, ARG97D, ASN132B, ASN132D, ASP130B, ASP130D, ASP26B, ASP26D, ASP89B, ASP89D, GLN96B, GLN96D, GLU128B, GLU128D, GLU303B, GLU303D, GLU92B, GLU92D, GLU93B, GLU93D, GLU94B, GLU94D, GLY104B, GLY104D, GLY23B, GLY23D, GLY297B, GLY297D, GLY298B, GLY298D, GLY91B, GLY91D, GLY98B, GLY98D, LEU133B, LEU133D, LEU25B, LEU25D, LEU71B, LEU71D, LYS304B, LYS304D, LYS73B, LYS73D, MET302B, MET302D, PRO100B, PRO100D, PRO24B, PRO24D, PRO296B, PRO296D, PRO84B, PRO84D, PRO88B, PRO88D, SER103B, SER103D, SER70B, SER70D, SER95B, SER95D, TRP90B, TRP90D, VAL300B, VAL300D
• C-D: ALA250C, ALA250D, ALA46C, ALA46D, ALA48C, ALA48D, ARG278C, ARG278D, ARG97C, ARG97D, ASN114C, ASN114D, ASN163C, ASN163D, ASN264C, ASN264D, ASN266C, ASN266D, ASN273C, ASN273D, ASP168C, ASP168D, ASP237C, ASP237D, ASP245C, ASP245D, ASP261C, ASP261D, ASP272C, ASP272D, GLU160C, GLU160D, GLU270C, GLU270D, GLU280C, GLU280D, GLU93C, GLU93D, GLU94C, GLU94D, GLY104C, GLY104D, GLY105C, GLY105D, GLY108C, GLY108D, GLY259C, GLY259D, GLY263C, GLY263D, GLY269C, GLY269D, GLY271C, GLY271D, GLY282C, GLY282D, GLY284C, GLY284D, GLY286C, GLY286D, GLY292C, GLY292D, GLY293C, GLY293D, GLY47C, GLY47D, GLY50C, GLY50D, GLY98C, GLY98D, HIS102C, HIS102D, HIS157C, HIS157D, HIS247C, HIS247D, HIS287C, HIS287D, HIS289C, HIS289D, HIS291C, HIS291D, HIS42C, HIS42D, ILE241C, ILE241D, ILE256C, ILE256D, ILE262C, ILE262D, ILE274C, ILE274D, ILE276C, ILE276D, ILE290C, ILE290D, ILE49C, ILE49D, ILE86C, ILE86D, LEU107C, LEU107D, LEU161C, LEU161D, LEU268C, LEU268D, LEU294C, LEU294D, LYS165C, LYS165D, LYS234C, LYS234D, LYS238C, LYS238D, LYS254C, LYS254D, LYS257C, LYS257D, LYS288C, LYS288D, MET101C, MET101D, MET106C, MET106D, MET285C, MET285D, PHE249C, PHE249D, PRO100C, PRO100D, PRO258C, PRO258D, PRO275C, PRO275D, PRO277C, PRO277D, PRO296C, PRO296D, SER103C, SER103D, SER260C, SER260D, SER279C, SER279D, SER39C, SER39D, THR154C, THR154D, THR295C, THR295D, THR43C, THR43D, TRP110C, TRP110D, TRP281C, TRP281D, TYR267C, TYR267D, TYR99C, TYR99D, VAL236C, VAL236D, VAL246C, VAL246D, VAL253C, VAL253D, VAL265C, VAL265D, VAL283C, VAL283D