2OQE

crystal structure of hansenula polymorpha amine oxidase in complex with xe to 1.6 angstroms

• Total interactions analyzed: 15
• Total true interactions: 15
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 567
  • Norm. En. per Res.: -5.3356
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-515.8182	-405.6779	-2098.29	-3019.7861	575	72	37	78359	38	180	163
A-C	0.0	11.0317	-43.9178	-32.8861	31	1	0	2029	0	2	3
A-D	0.0	0.0	-0.1183	-0.1183	2	0	0	23	0	0	0
A-E	0.0	11.3174	-44.7345	-33.4171	32	2	0	2075	0	2	4
A-F	-15.8464	38.3196	-124.54	-102.0668	78	7	0	5251	0	50	48
B-C	-12.2855	38.9034	-125.834	-99.2161	78	4	0	5311	0	49	49
B-D	0.0	11.1322	-44.0643	-32.9321	32	1	0	2068	0	2	4
B-E	0.0	0.0	-0.1096	-0.1096	2	0	0	22	0	0	0
B-F	0.0	10.9464	-42.8838	-31.9374	31	1	0	2025	0	2	3
C-D	-503.8134	-415.9943	-2105.46	-3025.2678	567	68	37	77884	37	175	159
C-E	0.0	10.9813	-44.6563	-33.675	33	1	0	2105	0	2	3
C-F	0.0	0.0	-0.1677	-0.1677	2	0	0	29	0	0	0
D-E	-10.617	41.964	-122.559	-91.212	72	6	0	5134	0	48	46
D-F	0.0	11.0609	-45.1546	-34.0937	31	1	0	2108	0	2	4
E-F	-468.0886	-414.9511	-2115.34	-2998.3797	567	70	37	78400	38	176	158

Interface residues

• A-B: ALA221A, ALA221B, ALA234A, ALA234B, ALA239A, ALA239B, ALA384A, ALA384B, ALA391A, ALA391B, ALA402A, ALA402B, ALA403A, ALA403B, ALA418A, ALA418B, ALA440A, ALA440B, ALA480A, ALA480B, ALA497A, ALA497B, ALA518A, ALA518B, ALA553A, ALA553B, ALA560A, ALA560B, ALA627A, ALA627B, ALA636A, ALA636B, ALA662A, ALA662B, ALA668A, ALA668B, ARG129A, ARG129B, ARG163A, ARG163B, ARG178A, ARG178B, ARG236A, ARG236B, ARG290A, ARG290B, ARG314A, ARG314B, ARG380A, ARG380B, ARG390A, ARG390B, ARG420A, ARG420B, ARG424A, ARG424B, ARG446A, ARG446B, ARG521A, ARG521B, ARG644A, ARG644B, ARG646A, ARG646B, ARG670A, ARG670B, ASN222A, ASN222B, ASN243A, ASN243B, ASN263A, ASN263B, ASN284A, ASN284B, ASN330A, ASN330B, ASN382A, ASN382B, ASN404A, ASN404B, ASN450A, ASN450B, ASN455A, ASN455B, ASN492A, ASN492B, ASN496A, ASN496B, ASN514A, ASN514B, ASN532A, ASN532B, ASN652A, ASN652B, ASP120A, ASP120B, ASP154A, ASP154B, ASP161A, ASP161B, ASP180A, ASP180B, ASP182A, ASP182B, ASP183A, ASP183B, ASP285A, ASP285B, ASP337A, ASP337B, ASP369A, ASP369B, ASP370A, ASP370B, ASP378A, ASP378B, ASP381A, ASP381B, ASP416A, ASP416B, ASP479A, ASP479B, ASP630A, ASP630B, ASP656A, ASP656B, CYS122A, CYS122B, CYS153A, CYS153B, CYS336A, CYS336B, CYS338A, CYS338B, CYS408A, CYS408B, CYS478A, CYS478B, CYS548A, CYS548B, GLN185A, GLN185B, GLN246A, GLN246B, GLN313A, GLN313B, GLN398A, GLN398B, GLN415A, GLN415B, GLN457A, GLN457B, GLN547A, GLN547B, GLN658A, GLN658B, GLU119A, GLU119B, GLU125A, GLU125B, GLU162A, GLU162B, GLU181A, GLU181B, GLU238A, GLU238B, GLU248A, GLU248B, GLU309A, GLU309B, GLU367A, GLU367B, GLU368A, GLU368B, GLU406A, GLU406B, GLU439A, GLU439B, GLU491A, GLU491B, GLU501A, GLU501B, GLU516A, GLU516B, GLU555A, GLU555B, GLU629A, GLU629B, GLU637A, GLU637B, GLU651A, GLU651B, GLU667A, GLU667B, GLY233A, GLY233B, GLY249A, GLY249B, GLY306A, GLY306B, GLY326A, GLY326B, GLY335A, GLY335B, GLY340A, GLY340B, GLY371A, GLY371B, GLY417A, GLY417B, GLY427A, GLY427B, GLY441A, GLY441B, GLY444A, GLY444B, GLY488A, GLY488B, GLY495A, GLY495B, GLY520A, GLY520B, GLY536A, GLY536B, GLY556A, GLY556B, GLY654A, GLY654B, HIS149B, HIS218A, HIS218B, HIS227A, HIS227B, HIS286A, HIS286B, HIS312A, HIS312B, HIS316A, HIS316B, HIS366A, HIS366B, HIS376A, HIS376B, HIS454A, HIS454B, HIS456A, HIS456B, HIS458A, HIS458B, HIS624A, HIS624B, HIS647A, HIS647B, ILE229A, ILE229B, ILE242A, ILE242B, ILE342A, ILE357A, ILE357B, ILE399A, ILE399B, ILE428A, ILE428B, ILE622A, ILE622B, ILE657A, ILE657B, LEU121A, LEU121B, LEU174A, LEU174B, LEU332A, LEU332B, LEU334A, LEU334B, LEU372A, LEU372B, LEU373A, LEU373B, LEU387A, LEU387B, LEU409A, LEU409B, LEU425A, LEU425B, LEU429A, LEU429B, LEU434A, LEU434B, LEU487A, LEU487B, LEU551A, LEU551B, LEU552A, LEU552B, LEU558A, LEU558B, LEU633A, LEU633B, LEU655A, LEU655B, LYS219A, LYS226A, LYS226B, LYS231A, LYS231B, LYS315A, LYS315B, LYS339A, LYS339B, LYS360A, LYS360B, LYS375A, LYS375B, LYS393A, LYS393B, LYS481A, LYS481B, LYS537A, LYS537B, LYS542A, LYS542B, LYS554A, LYS554B, LYS561A, LYS561B, LYS669A, LYS669B, MET228A, MET228B, MET235A, MET235B, MET328A, MET328B, MET414A, MET414B, MET493A, MET493B, MET642A, MET642B, MET663A, MET663B, PHE223A, PHE223B, PHE252A, PHE252B, PHE264A, PHE264B, PHE310A, PHE310B, PHE349A, PHE349B, PHE374A, PHE374B, PHE379A, PHE379B, PHE383A, PHE383B, PHE400A, PHE400B, PHE498A, PHE498B, PHE625A, PHE625B, PHE631A, PHE631B, PHE648A, PHE648B, PHE649A, PHE649B, PRO155A, PRO155B, PRO225A, PRO225B, PRO237A, PRO237B, PRO240A, PRO240B, PRO241A, PRO241B, PRO247A, PRO247B, PRO304A, PRO304B, PRO308A, PRO308B, PRO311A, PRO311B, PRO331A, PRO331B, PRO442A, PRO442B, PRO449A, PRO449B, PRO484A, PRO484B, PRO486A, PRO486B, PRO490A, PRO490B, PRO533A, PRO533B, PRO539A, PRO539B, PRO549A, PRO549B, PRO550A, PRO550B, PRO626A, PRO626B, PRO628A, PRO628B, PRO632A, PRO632B, PRO635A, PRO635B, PRO638A, PRO638B, PRO645A, PRO645B, PRO653A, PRO653B, PRO659A, PRO659B, SER123A, SER123B, SER184A, SER184B, SER251A, SER251B, SER262A, SER262B, SER307A, SER307B, SER333A, SER333B, SER377A, SER377B, SER386A, SER386B, SER397A, SER397B, SER482A, SER482B, SER483A, SER483B, SER489A, SER489B, SER500A, SER500B, SER517A, SER517B, SER522A, SER522B, SER535A, SER535B, SER540A, SER540B, SER545A, SER545B, SER557A, SER557B, SER569A, SER569B, SER660A, SER660B, SER666A, SER666B, THR117B, THR124A, THR124B, THR245A, THR245B, THR329A, THR329B, THR358A, THR358B, THR385A, THR385B, THR389A, THR389B, THR392A, THR392B, THR401A, THR401B, THR426A, THR426B, THR445A, THR445B, THR519A, THR519B, THR546A, THR546B, THR623A, THR623B, THR640A, THR640B, THR650A, THR650B, THR664A, THR664B, THR665A, THR665B, TRP156A, TRP156B, TRP261A, TRP261B, TRP443A, TRP443B, TYR152A, TYR152B, TYR160A, TYR160B, TYR176A, TYR176B, TYR186A, TYR186B, TYR224A, TYR224B, TYR283A, TYR283B, TYR305A, TYR305B, TYR327A, TYR327B, TYR407A, TYR407B, TYR410A, TYR410B, TYR448A, TYR448B, TYR485A, TYR485B, TYR494A, TYR494B, TYR499A, TYR499B, TYR515A, TYR515B, TYR534A, TYR534B, TYR541A, TYR541B, TYR661A, TYR661B, VAL118A, VAL118B, VAL151A, VAL151B, VAL175A, VAL175B, VAL232A, VAL232B, VAL244A, VAL244B, VAL250A, VAL250B, VAL303A, VAL303B, VAL341A, VAL341B, VAL359A, VAL359B, VAL388A, VAL388B, VAL447A, VAL447B, VAL451A, VAL451B, VAL531B, VAL544A, VAL544B, VAL559A, VAL559B
• A-C: ARG596C, ARG599C, ASN492A, ASP593C, ASP604C, GLU491A, GLU555C, GLU600C, GLY488A, GLY556C, GLY592C, GLY594C, GLY603C, GLY605C, ILE602C, LEU487A, LYS509C, LYS561C, MET493A, MET598C, PRO486A, PRO490A, PRO564C, SER489A, SER557C, SER591C, TRP590C, TRP601C, TYR485A, TYR494A, VAL595C
• A-D: LEU487A, LEU487D
• A-E: ARG596A, ARG599A, ASN492E, ASP593A, ASP604A, GLU491E, GLU555A, GLU600A, GLY488E, GLY556A, GLY592A, GLY594A, GLY603A, GLY605A, ILE602A, LEU487E, LYS509A, LYS561A, MET493E, MET598A, PRO486E, PRO490E, PRO564A, SER489E, SER557A, SER591A, SER606A, TRP590A, TRP601A, TYR485E, TYR494E, VAL595A
• A-F: ALA108A, ALA108F, ARG163A, ARG163F, ARG596A, ARG596F, ASN210F, ASP161A, ASP161F, ASP207A, ASP207F, ASP593A, ASP593F, GLN313A, GLN313F, GLN589A, GLN589F, GLU110A, GLU110F, GLU162A, GLU162F, GLU555A, GLU555F, GLY165A, GLY165F, GLY167A, GLY167F, GLY556A, GLY556F, GLY592A, GLY592F, GLY594A, GLY594F, GLY87A, GLY87F, ILE195A, ILE195F, ILE204A, ILE204F, ILE206A, ILE206F, LEU109A, LEU109F, LEU170A, LEU170F, LEU558A, LEU558F, LYS168A, LYS168F, LYS202A, LYS202F, LYS561A, LYS561F, LYS88A, PHE205A, PHE205F, PHE310A, PHE310F, PRO89A, PRO89F, SER557A, SER557F, SER591A, SER591F, THR111A, THR111F, THR166A, THR166F, TRP164A, TRP164F, TRP590A, TRP590F, TYR160A, TYR160F, VAL112A, VAL112F, VAL595A, VAL595F
• B-C: ALA108B, ALA108C, ARG163B, ARG163C, ARG596B, ARG596C, ASN210B, ASN210C, ASP161B, ASP161C, ASP207B, ASP207C, ASP593B, ASP593C, GLN313B, GLN313C, GLN589B, GLN589C, GLU110B, GLU110C, GLU162B, GLU162C, GLU555B, GLU555C, GLY165B, GLY165C, GLY167B, GLY167C, GLY556B, GLY556C, GLY592B, GLY592C, GLY594B, GLY594C, GLY87B, GLY87C, ILE195B, ILE195C, ILE204B, ILE204C, ILE206B, ILE206C, LEU109B, LEU109C, LEU170B, LEU170C, LEU558B, LEU558C, LYS168B, LYS168C, LYS202B, LYS202C, LYS561B, LYS561C, PHE205B, PHE205C, PHE310B, PHE310C, PRO89B, PRO89C, SER557B, SER557C, SER591B, SER591C, THR111B, THR111C, THR166B, THR166C, TRP164B, TRP164C, TRP590B, TRP590C, TYR160B, TYR160C, VAL112B, VAL112C, VAL595B, VAL595C
• B-D: ARG596B, ARG599B, ASN492D, ASP593B, ASP604B, GLU491D, GLU555B, GLU600B, GLY488D, GLY556B, GLY592B, GLY594B, GLY603B, GLY605B, ILE602B, LEU487D, LYS509B, LYS561B, MET493D, MET598B, PRO486D, PRO490D, PRO564B, SER489D, SER557B, SER591B, SER606B, TRP590B, TRP601B, TYR485D, TYR494D, VAL595B
• B-E: LEU487B, LEU487E
• B-F: ARG596F, ARG599F, ASN492B, ASP593F, ASP604F, GLU491B, GLU555F, GLU600F, GLY488B, GLY556F, GLY592F, GLY594F, GLY603F, GLY605F, ILE602F, LEU487B, LYS509F, LYS561F, MET493B, MET598F, PRO486B, PRO490B, PRO564F, SER489B, SER557F, SER591F, TRP590F, TRP601F, TYR485B, TYR494B, VAL595F
• C-D: ALA221C, ALA221D, ALA234C, ALA234D, ALA239C, ALA239D, ALA384C, ALA384D, ALA391C, ALA391D, ALA402C, ALA402D, ALA403C, ALA403D, ALA418C, ALA418D, ALA440C, ALA440D, ALA480C, ALA480D, ALA497C, ALA497D, ALA518C, ALA518D, ALA553C, ALA553D, ALA560C, ALA560D, ALA627C, ALA627D, ALA636C, ALA636D, ALA662C, ALA662D, ALA668C, ALA668D, ARG129C, ARG129D, ARG163C, ARG163D, ARG178C, ARG178D, ARG236C, ARG236D, ARG290C, ARG290D, ARG314C, ARG314D, ARG380C, ARG380D, ARG390C, ARG390D, ARG420C, ARG420D, ARG424C, ARG424D, ARG446C, ARG446D, ARG521C, ARG521D, ARG644C, ARG644D, ARG646C, ARG646D, ARG670C, ARG670D, ASN222C, ASN222D, ASN243C, ASN243D, ASN263C, ASN263D, ASN284C, ASN284D, ASN330C, ASN330D, ASN382C, ASN382D, ASN404C, ASN404D, ASN450C, ASN450D, ASN455C, ASN455D, ASN492C, ASN492D, ASN496C, ASN496D, ASN514C, ASN514D, ASN532C, ASN532D, ASN652C, ASN652D, ASP154C, ASP154D, ASP161C, ASP161D, ASP180C, ASP180D, ASP182C, ASP182D, ASP183C, ASP183D, ASP285C, ASP285D, ASP337C, ASP337D, ASP369C, ASP369D, ASP370C, ASP370D, ASP378C, ASP378D, ASP381C, ASP381D, ASP416C, ASP416D, ASP479C, ASP479D, ASP630C, ASP630D, ASP656C, ASP656D, CYS122C, CYS122D, CYS153C, CYS153D, CYS336C, CYS336D, CYS338C, CYS338D, CYS364D, CYS408C, CYS408D, CYS478C, CYS478D, CYS548C, CYS548D, GLN185C, GLN185D, GLN246C, GLN246D, GLN313C, GLN313D, GLN398D, GLN415C, GLN415D, GLN457C, GLN457D, GLN547C, GLN547D, GLN658C, GLN658D, GLU119C, GLU125C, GLU125D, GLU162C, GLU162D, GLU181C, GLU181D, GLU238C, GLU238D, GLU248C, GLU248D, GLU309C, GLU309D, GLU367C, GLU367D, GLU368C, GLU368D, GLU406C, GLU406D, GLU439C, GLU439D, GLU491C, GLU491D, GLU501C, GLU501D, GLU516C, GLU516D, GLU555C, GLU555D, GLU629C, GLU629D, GLU637C, GLU637D, GLU651C, GLU651D, GLU667C, GLU667D, GLY233C, GLY233D, GLY249C, GLY249D, GLY306C, GLY306D, GLY326C, GLY326D, GLY335C, GLY335D, GLY340C, GLY340D, GLY371C, GLY371D, GLY417C, GLY417D, GLY427C, GLY427D, GLY441C, GLY441D, GLY444C, GLY444D, GLY488C, GLY488D, GLY495C, GLY495D, GLY520C, GLY520D, GLY536C, GLY536D, GLY556C, GLY556D, GLY654C, GLY654D, HIS149C, HIS149D, HIS218C, HIS218D, HIS227C, HIS227D, HIS286C, HIS286D, HIS312C, HIS312D, HIS316C, HIS316D, HIS366C, HIS366D, HIS376C, HIS376D, HIS454C, HIS454D, HIS456C, HIS456D, HIS458C, HIS458D, HIS624C, HIS624D, HIS647C, HIS647D, ILE229C, ILE229D, ILE242C, ILE242D, ILE342C, ILE357C, ILE399C, ILE399D, ILE428C, ILE428D, ILE622C, ILE622D, ILE657C, ILE657D, LEU121C, LEU121D, LEU174C, LEU174D, LEU332C, LEU332D, LEU334C, LEU334D, LEU372C, LEU372D, LEU373C, LEU373D, LEU387C, LEU387D, LEU394C, LEU425C, LEU425D, LEU429C, LEU429D, LEU434C, LEU434D, LEU487C, LEU487D, LEU551C, LEU551D, LEU552C, LEU552D, LEU558C, LEU558D, LEU633C, LEU633D, LEU655C, LEU655D, LYS219C, LYS226C, LYS226D, LYS231C, LYS231D, LYS315C, LYS315D, LYS339C, LYS339D, LYS360D, LYS375C, LYS375D, LYS393C, LYS393D, LYS481C, LYS481D, LYS537C, LYS537D, LYS542C, LYS542D, LYS554C, LYS554D, LYS561C, LYS561D, LYS669C, LYS669D, MET228C, MET228D, MET235C, MET235D, MET328C, MET328D, MET414C, MET414D, MET493C, MET493D, MET634C, MET634D, MET642C, MET642D, MET663C, MET663D, PHE223C, PHE223D, PHE252C, PHE252D, PHE264C, PHE264D, PHE310C, PHE310D, PHE374C, PHE374D, PHE379C, PHE379D, PHE383C, PHE383D, PHE400C, PHE400D, PHE498C, PHE498D, PHE625C, PHE625D, PHE631C, PHE631D, PHE648C, PHE648D, PHE649C, PHE649D, PRO155C, PRO155D, PRO225C, PRO225D, PRO237C, PRO237D, PRO240C, PRO240D, PRO241C, PRO241D, PRO247C, PRO247D, PRO304C, PRO304D, PRO308C, PRO308D, PRO311C, PRO311D, PRO331C, PRO331D, PRO442C, PRO442D, PRO449C, PRO449D, PRO484C, PRO484D, PRO486C, PRO486D, PRO490C, PRO490D, PRO533C, PRO533D, PRO539C, PRO539D, PRO549C, PRO549D, PRO550C, PRO550D, PRO626C, PRO626D, PRO628C, PRO628D, PRO632C, PRO632D, PRO635C, PRO635D, PRO638C, PRO638D, PRO645C, PRO645D, PRO653C, PRO653D, PRO659C, PRO659D, SER123C, SER123D, SER184C, SER184D, SER251C, SER251D, SER262C, SER262D, SER307C, SER307D, SER333C, SER333D, SER377C, SER377D, SER386C, SER386D, SER397C, SER482C, SER482D, SER483C, SER483D, SER489C, SER489D, SER500C, SER500D, SER517C, SER517D, SER522C, SER522D, SER535C, SER535D, SER540C, SER540D, SER545C, SER545D, SER557C, SER557D, SER569C, SER569D, SER660C, SER660D, SER666C, SER666D, THR124C, THR124D, THR245C, THR245D, THR329C, THR329D, THR358C, THR358D, THR385C, THR385D, THR389C, THR389D, THR392C, THR392D, THR401C, THR401D, THR426C, THR426D, THR445C, THR445D, THR519C, THR519D, THR546C, THR546D, THR623C, THR623D, THR640C, THR640D, THR650C, THR650D, THR664C, THR664D, THR665C, THR665D, TRP156C, TRP156D, TRP261C, TRP261D, TRP443C, TRP443D, TYR152C, TYR152D, TYR160C, TYR160D, TYR176C, TYR176D, TYR186C, TYR186D, TYR224C, TYR224D, TYR283C, TYR283D, TYR305C, TYR305D, TYR327C, TYR327D, TYR407C, TYR407D, TYR410C, TYR410D, TYR448C, TYR448D, TYR485C, TYR485D, TYR494C, TYR494D, TYR499C, TYR499D, TYR515C, TYR515D, TYR534C, TYR534D, TYR541C, TYR541D, TYR661C, TYR661D, VAL118C, VAL118D, VAL151C, VAL151D, VAL175C, VAL175D, VAL232C, VAL232D, VAL244C, VAL244D, VAL250C, VAL250D, VAL303C, VAL303D, VAL341C, VAL341D, VAL359C, VAL359D, VAL388C, VAL388D, VAL447C, VAL447D, VAL451C, VAL451D, VAL544C, VAL544D, VAL559C, VAL559D
• C-E: ARG596E, ARG599E, ASN492C, ASP593E, ASP604E, GLU491C, GLU555E, GLU600E, GLY488C, GLY556E, GLY592E, GLY594E, GLY603E, GLY605E, ILE602E, LEU487C, LYS509E, LYS561E, MET493C, MET598E, PRO486C, PRO490C, PRO564E, SER489C, SER557E, SER591E, SER606E, TRP590E, TRP601E, TYR160E, TYR485C, TYR494C, VAL595E
• C-F: LEU487C, LEU487F
• D-E: ALA108D, ALA108E, ARG163D, ARG163E, ARG596D, ARG596E, ASP161D, ASP161E, ASP207D, ASP207E, ASP593D, ASP593E, GLN313D, GLN313E, GLN589D, GLN589E, GLU110D, GLU110E, GLU162D, GLU162E, GLU555D, GLU555E, GLY165D, GLY165E, GLY167D, GLY167E, GLY556D, GLY556E, GLY592D, GLY592E, GLY594D, GLY594E, ILE195D, ILE195E, ILE204D, ILE204E, ILE206D, ILE206E, LEU109D, LEU109E, LEU170D, LEU170E, LEU558D, LEU558E, LYS168D, LYS168E, LYS561D, LYS561E, PHE205D, PHE205E, PHE310D, PHE310E, PRO89D, PRO89E, SER557D, SER557E, SER591D, SER591E, THR111D, THR111E, THR166D, THR166E, TRP164D, TRP164E, TRP590D, TRP590E, TYR160D, TYR160E, VAL112D, VAL112E, VAL595D, VAL595E
• D-F: ARG596D, ARG599D, ASN492F, ASP593D, ASP604D, GLU491F, GLU555D, GLU600D, GLY488F, GLY556D, GLY592D, GLY594D, GLY603D, GLY605D, ILE602D, LEU487F, LYS509D, LYS561D, MET493F, MET598D, PRO486F, PRO490F, PRO564D, SER489F, SER557D, SER591D, TRP590D, TRP601D, TYR485F, TYR494F, VAL595D
• E-F: ALA221E, ALA221F, ALA234E, ALA234F, ALA239E, ALA239F, ALA384E, ALA384F, ALA391E, ALA391F, ALA402E, ALA402F, ALA403E, ALA403F, ALA418E, ALA418F, ALA440E, ALA440F, ALA480E, ALA480F, ALA497E, ALA497F, ALA518E, ALA518F, ALA553E, ALA553F, ALA560E, ALA560F, ALA627E, ALA627F, ALA636E, ALA636F, ALA662E, ALA662F, ALA668E, ALA668F, ARG129E, ARG129F, ARG163E, ARG163F, ARG178E, ARG178F, ARG236E, ARG236F, ARG290E, ARG290F, ARG314E, ARG314F, ARG380E, ARG380F, ARG390E, ARG390F, ARG420E, ARG420F, ARG424E, ARG424F, ARG446E, ARG446F, ARG521E, ARG521F, ARG644E, ARG644F, ARG646E, ARG646F, ARG670E, ARG670F, ASN222E, ASN222F, ASN243E, ASN243F, ASN263E, ASN263F, ASN284E, ASN284F, ASN330E, ASN330F, ASN382E, ASN382F, ASN404E, ASN404F, ASN450E, ASN450F, ASN455E, ASN455F, ASN492E, ASN492F, ASN496E, ASN496F, ASN514E, ASN514F, ASN532E, ASN532F, ASN652E, ASN652F, ASP154E, ASP154F, ASP161E, ASP161F, ASP180E, ASP180F, ASP182E, ASP182F, ASP183E, ASP183F, ASP285E, ASP285F, ASP337E, ASP337F, ASP369E, ASP369F, ASP370E, ASP370F, ASP378E, ASP378F, ASP381E, ASP381F, ASP416E, ASP416F, ASP479E, ASP479F, ASP630E, ASP630F, ASP656E, ASP656F, CYS122E, CYS122F, CYS153E, CYS153F, CYS336E, CYS336F, CYS338E, CYS338F, CYS408E, CYS408F, CYS478E, CYS478F, CYS548E, CYS548F, GLN185E, GLN185F, GLN246E, GLN246F, GLN313E, GLN313F, GLN398E, GLN415E, GLN415F, GLN457E, GLN457F, GLN547E, GLN547F, GLN658E, GLN658F, GLU119F, GLU125E, GLU125F, GLU162E, GLU162F, GLU181E, GLU181F, GLU238E, GLU238F, GLU248E, GLU248F, GLU309E, GLU309F, GLU367E, GLU367F, GLU368E, GLU368F, GLU406E, GLU406F, GLU439E, GLU439F, GLU491E, GLU491F, GLU501E, GLU501F, GLU516E, GLU516F, GLU555E, GLU555F, GLU629E, GLU629F, GLU637E, GLU637F, GLU651E, GLU651F, GLU667E, GLU667F, GLY233E, GLY233F, GLY249E, GLY249F, GLY306E, GLY306F, GLY326E, GLY326F, GLY335E, GLY335F, GLY340E, GLY340F, GLY371E, GLY371F, GLY417E, GLY417F, GLY427E, GLY427F, GLY441E, GLY441F, GLY444E, GLY444F, GLY488E, GLY488F, GLY495E, GLY495F, GLY520E, GLY520F, GLY536E, GLY536F, GLY556E, GLY556F, GLY654E, GLY654F, HIS149E, HIS149F, HIS218E, HIS218F, HIS227E, HIS227F, HIS286E, HIS286F, HIS312E, HIS312F, HIS316E, HIS316F, HIS366E, HIS366F, HIS376E, HIS376F, HIS454E, HIS454F, HIS456E, HIS456F, HIS458E, HIS458F, HIS624E, HIS624F, HIS647E, HIS647F, ILE229E, ILE229F, ILE242E, ILE242F, ILE342F, ILE357E, ILE357F, ILE399E, ILE399F, ILE428E, ILE428F, ILE622E, ILE622F, ILE657E, ILE657F, LEU121E, LEU121F, LEU174E, LEU174F, LEU332E, LEU332F, LEU334E, LEU334F, LEU372E, LEU372F, LEU373E, LEU373F, LEU387E, LEU387F, LEU394F, LEU425E, LEU425F, LEU429E, LEU429F, LEU434E, LEU434F, LEU487E, LEU487F, LEU551E, LEU551F, LEU552E, LEU552F, LEU558E, LEU558F, LEU633E, LEU633F, LEU655E, LEU655F, LYS219E, LYS226E, LYS226F, LYS231E, LYS231F, LYS315E, LYS315F, LYS339E, LYS339F, LYS360E, LYS375E, LYS375F, LYS393E, LYS393F, LYS481E, LYS481F, LYS537E, LYS537F, LYS542E, LYS542F, LYS554E, LYS554F, LYS561E, LYS561F, LYS669E, LYS669F, MET228E, MET228F, MET235E, MET235F, MET328E, MET328F, MET414E, MET414F, MET493E, MET493F, MET634E, MET634F, MET642E, MET642F, MET663E, MET663F, PHE223E, PHE223F, PHE252E, PHE252F, PHE264E, PHE264F, PHE310E, PHE310F, PHE374E, PHE374F, PHE379E, PHE379F, PHE383E, PHE383F, PHE400E, PHE400F, PHE498E, PHE498F, PHE625E, PHE625F, PHE631E, PHE631F, PHE648E, PHE648F, PHE649E, PHE649F, PRO155E, PRO155F, PRO225E, PRO225F, PRO237E, PRO237F, PRO240E, PRO240F, PRO241E, PRO241F, PRO247E, PRO247F, PRO304E, PRO304F, PRO308E, PRO308F, PRO311E, PRO311F, PRO331E, PRO331F, PRO442E, PRO442F, PRO449E, PRO449F, PRO484E, PRO484F, PRO486E, PRO486F, PRO490E, PRO490F, PRO533E, PRO533F, PRO539E, PRO539F, PRO549E, PRO549F, PRO550E, PRO550F, PRO626E, PRO626F, PRO628E, PRO628F, PRO632E, PRO632F, PRO635E, PRO635F, PRO638E, PRO638F, PRO645E, PRO645F, PRO653E, PRO653F, PRO659E, PRO659F, SER123E, SER123F, SER184E, SER184F, SER251E, SER251F, SER262E, SER262F, SER307E, SER307F, SER333E, SER333F, SER377E, SER377F, SER386E, SER386F, SER482E, SER482F, SER483E, SER483F, SER489E, SER489F, SER500E, SER500F, SER517E, SER517F, SER522E, SER522F, SER535E, SER535F, SER540E, SER540F, SER545E, SER545F, SER557E, SER557F, SER569E, SER569F, SER660E, SER660F, SER666E, SER666F, THR124E, THR124F, THR245E, THR245F, THR329E, THR329F, THR358E, THR385E, THR385F, THR389E, THR389F, THR392E, THR392F, THR401E, THR401F, THR426E, THR426F, THR445E, THR445F, THR519E, THR519F, THR546E, THR546F, THR623E, THR623F, THR640E, THR640F, THR650E, THR650F, THR664E, THR664F, THR665E, THR665F, TRP156E, TRP156F, TRP261E, TRP261F, TRP443E, TRP443F, TYR152E, TYR152F, TYR160E, TYR160F, TYR176E, TYR176F, TYR186E, TYR186F, TYR224E, TYR224F, TYR283E, TYR283F, TYR305E, TYR305F, TYR327E, TYR327F, TYR407E, TYR407F, TYR410E, TYR410F, TYR448E, TYR448F, TYR485E, TYR485F, TYR494E, TYR494F, TYR499E, TYR499F, TYR515E, TYR515F, TYR534E, TYR534F, TYR541E, TYR541F, TYR661E, TYR661F, VAL118E, VAL118F, VAL151E, VAL151F, VAL175E, VAL175F, VAL232E, VAL232F, VAL244E, VAL244F, VAL250E, VAL250F, VAL303E, VAL303F, VAL341E, VAL341F, VAL359E, VAL359F, VAL388E, VAL388F, VAL447E, VAL447F, VAL451E, VAL451F, VAL531E, VAL531F, VAL544E, VAL544F, VAL559E, VAL559F