2OME

crystal structure of human ctbp2 dehydrogenase complexed with nad(h)

• Total interactions analyzed: 28
• Total true interactions: 18
• Strongest Interaction:
  • Chains: G-H
  • Int. Res.: 245
  • Norm. En. per Res.: -5.0249
• Hub Node: A(6)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-125.3319	-239.9768	-835.549	-1200.8576	245	34	20	34166	12	83	70
A-C	0.0	5.706	-17.5728	-11.8668	25	5	0	1013	0	4	11
A-D	-48.5773	-119.7718	-204.795	-373.1441	89	14	2	8900	14	26	28
A-E	-21.5974	-4.5867	-73.2412	-99.4253	37	2	0	2671	0	11	12
A-G	0.0	0.0	-1.3138	-1.3138	14	0	0	246	0	7	7
A-H	0.0	0.0	-0.0006	-0.0006	4	0	0	2	0	4	5
B-C	-64.033	-123.1335	-205.605	-392.7716	88	6	2	8743	13	25	28
B-D	0.0	3.8373	-19.5911	-15.7538	26	2	0	1036	0	4	11
B-H	0.0	0.0	-7.169	-7.169	21	0	0	381	0	7	7
C-D	-103.0441	-222.5748	-836.963	-1162.5819	241	46	20	34163	11	84	69
D-E	0.0	0.0	-12.4394	-12.4394	25	0	0	446	0	11	12
D-H	-15.6478	-3.4518	-69.0318	-88.1313	35	2	0	2571	0	11	11
E-F	-128.2286	-228.7566	-837.092	-1194.0772	245	39	20	34306	11	85	70
E-G	0.0	6.5629	-19.9408	-13.3779	26	4	0	1064	0	4	11
E-H	-70.4439	-119.2039	-178.582	-368.2298	85	11	2	8451	13	25	28
F-G	-77.0141	-126.6911	-196.338	-400.0432	94	10	2	8697	10	24	27
F-H	0.0	5.3305	-17.9496	-12.6191	26	1	0	910	0	4	11
G-H	-121.0411	-268.8542	-841.215	-1231.1103	245	40	20	33972	12	84	70

Interface residues

• A-B: ALA129A, ALA129B, ALA130A, ALA130B, ALA135A, ALA135B, ALA155A, ALA155B, ALA172A, ALA172B, ALA175A, ALA175B, ALA176A, ALA176B, ALA194A, ALA194B, ALA196A, ALA196B, ALA199A, ALA199B, ALA201A, ALA201B, ALA293A, ALA294A, ALA294B, ALA306A, ALA306B, ALA313A, ALA313B, ALA323A, ALA323B, ALA329A, ALA329B, ALA62A, ALA62B, ARG103A, ARG103B, ARG147A, ARG147B, ARG148A, ARG148B, ARG157A, ARG157B, ARG161A, ARG161B, ARG169A, ARG169B, ARG177A, ARG177B, ARG179A, ARG179B, ARG198A, ARG198B, ARG291A, ARG291B, ARG334A, ARG334B, ARG42A, ARG42B, ASN144A, ASN144B, ASN149A, ASN149B, ASN315A, ASN315B, ASP136A, ASP136B, ASP296A, ASP296B, ASP312A, ASP312B, ASP40A, ASP40B, ASP43A, ASP43B, ASP61A, ASP61B, CYS140A, CYS140B, CYS318A, CYS318B, CYS44A, CYS44B, GLN154A, GLN154B, GLN163A, GLN163B, GLN167A, GLN167B, GLN307A, GLN307B, GLN328A, GLN328B, GLN63A, GLN63B, GLU132A, GLU132B, GLU133A, GLU133B, GLU158A, GLU158B, GLU166A, GLU166B, GLU170A, GLU170B, GLU181A, GLU181B, GLU301A, GLU301B, GLU327A, GLU327B, GLU332A, GLU332B, GLU47A, GLU47B, GLU67B, GLY159A, GLY159B, GLY174A, GLY174B, GLY203A, GLY203B, GLY41A, GLY41B, HIS141A, HIS141B, HIS298A, HIS298B, HIS321A, HIS321B, HIS83A, HIS83B, ILE104A, ILE104B, ILE139A, ILE139B, ILE142A, ILE142B, ILE168A, ILE168B, ILE178A, ILE178B, ILE317A, ILE317B, ILE85A, ILE85B, LEU143A, LEU143B, LEU145A, LEU145B, LEU152A, LEU152B, LEU156A, LEU156B, LEU295A, LEU295B, LEU310A, LEU310B, LEU316A, LEU316B, LEU331A, LEU331B, LEU38A, LEU38B, LYS200A, LYS200B, LYS311A, LYS311B, MET333A, MET333B, MET81A, MET81B, PHE202A, PHE202B, PHE204A, PHE204B, PHE303A, PHE303B, PHE305A, PHE305B, PHE59A, PHE59B, PRO302A, PRO302B, PRO314A, PRO314B, PRO320A, PRO320B, SER128A, SER128B, SER137A, SER137B, SER164A, SER164B, SER173A, SER173B, SER304A, SER304B, SER326A, SER326B, SER330A, SER330B, SER64B, THR134A, THR134B, THR138A, THR138B, THR150A, THR150B, THR160A, THR160B, THR319A, THR319B, THR322A, THR322B, THR45A, THR45B, THR84A, THR84B, TRP151A, TRP151B, TRP324A, TRP324B, TYR146A, TYR146B, TYR153A, TYR153B, TYR325A, TYR325B, TYR82A, TYR82B, VAL131A, VAL131B, VAL162A, VAL162B, VAL165A, VAL165B, VAL171A, VAL171B, VAL195A, VAL195B, VAL197A, VAL197B, VAL46A, VAL46B
• A-C: ALA201A, ALA201C, ARG177A, ARG177C, ARG179A, ARG179C, ARG219A, ARG219C, GLN224A, GLN224C, GLU218A, GLU218C, GLY203A, GLY203C, GLY222A, GLY222C, LEU221A, LEU221C, LYS200A, LYS200C, PHE202C, SER220A, SER220C, VAL223A, VAL223C
• A-D: ALA129A, ALA129D, ALA130A, ALA130D, ALA135A, ALA135D, ALA194A, ALA194D, ALA196A, ALA196D, ALA329A, ALA329D, ARG190A, ARG190D, ARG198A, ARG198D, ARG219A, ARG219D, ARG225A, ARG225D, ARG343A, ARG343D, ARG354A, ARG354D, ASN125A, ASN125D, ASN355A, ASN355D, ASP215A, ASP215D, CYS356D, GLN193A, GLN193D, GLN214A, GLN214D, GLN328A, GLN328D, GLU132A, GLU132D, GLU133A, GLU133D, GLU218A, GLU218D, GLU332A, GLU332D, GLY189A, GLY189D, GLY192A, GLY192D, GLY216A, GLY216D, GLY222A, GLY222D, ILE126A, ILE126D, ILE217A, ILE217D, LEU213A, LEU213D, LEU221A, LEU221D, LYS200A, LYS200D, MET333D, PHE188A, PHE188D, PRO127A, PRO127D, PRO211A, SER106D, SER128A, SER128D, SER220A, SER220D, SER326A, THR191A, THR191D, TYR108D, TYR227A, TYR227D, VAL131A, VAL131D, VAL195A, VAL195D, VAL197A, VAL197D, VAL223A, VAL223D, VAL357D
• A-E: ALA265E, ALA344A, ARG262E, ARG289E, ARG342A, ARG343A, ARG348A, ARG354A, ARG99A, ASP231E, ASP53A, GLN224E, GLN230E, GLN235E, GLN260E, GLN263E, GLU351A, GLY264E, GLY347A, ILE207E, ILE258E, ILE345A, ILE349A, LEU233E, LEU353A, LEU54A, LYS259E, MET261E, PHE362A, PRO350A, SER236E, SER352A, THR182E, THR257E, THR346A, TYR234E, VAL226E
• A-G: ARG179G, ARG262G, ARG33A, ASP237G, ASP53A, GLN224G, GLN235G, GLU181G, GLY180G, LYS52A, SER205G, THR182G, THR56A, TYR234G
• A-H: GLN328A, GLN328H, LYS52A, LYS52H
• B-C: ALA129B, ALA129C, ALA130B, ALA130C, ALA135B, ALA135C, ALA194B, ALA194C, ALA196B, ALA196C, ALA329B, ALA329C, ALA336B, ARG190B, ARG190C, ARG198B, ARG198C, ARG219B, ARG219C, ARG225B, ARG225C, ARG343B, ARG343C, ARG354B, ARG354C, ASN125B, ASN355B, ASN355C, ASP215B, ASP215C, CYS356B, GLN193B, GLN193C, GLN214B, GLN214C, GLN328B, GLN328C, GLU132B, GLU132C, GLU133B, GLU133C, GLU218B, GLU218C, GLU332B, GLU332C, GLY189B, GLY189C, GLY192B, GLY192C, GLY216B, GLY216C, GLY222B, GLY222C, ILE126B, ILE126C, ILE217B, ILE217C, LEU213B, LEU213C, LEU221B, LEU221C, LYS200B, LYS200C, MET333B, PHE188B, PHE188C, PRO127B, PRO127C, PRO211B, PRO211C, SER128B, SER128C, SER220B, SER220C, THR191B, THR191C, TYR108B, TYR227B, TYR227C, VAL131B, VAL131C, VAL195B, VAL195C, VAL197B, VAL197C, VAL223B, VAL223C, VAL357B
• B-D: ALA201B, ALA201D, ARG177B, ARG177D, ARG179B, ARG179D, ARG219B, ARG219D, GLN224B, GLN224D, GLU218B, GLU218D, GLY203B, GLY203D, GLY222B, GLY222D, LEU221B, LEU221D, LYS200B, LYS200D, PHE202B, PHE202D, SER220B, SER220D, VAL223B, VAL223D
• B-H: ARG179B, ARG262B, ARG33H, ASP237B, ASP53H, GLN224B, GLN235B, GLN66B, GLU181B, GLU67B, GLY180B, HIS2H, ILE207B, LYS52H, LYS71H, LYS94B, SER205B, SER64B, THR182B, THR56H, TYR234B
• C-D: ALA129C, ALA129D, ALA130C, ALA130D, ALA135C, ALA135D, ALA155C, ALA155D, ALA172C, ALA172D, ALA175C, ALA175D, ALA176C, ALA176D, ALA194C, ALA194D, ALA196C, ALA196D, ALA199C, ALA199D, ALA201C, ALA201D, ALA294C, ALA294D, ALA306C, ALA306D, ALA313C, ALA313D, ALA323C, ALA323D, ALA329C, ALA329D, ARG103C, ARG103D, ARG147C, ARG147D, ARG148C, ARG148D, ARG157C, ARG157D, ARG161C, ARG161D, ARG169C, ARG169D, ARG177C, ARG177D, ARG179C, ARG179D, ARG198C, ARG198D, ARG291C, ARG291D, ARG334C, ARG334D, ARG42C, ARG42D, ASN144C, ASN144D, ASN149C, ASN149D, ASN315C, ASN315D, ASP136C, ASP136D, ASP296C, ASP296D, ASP312C, ASP312D, ASP40C, ASP40D, ASP43C, ASP43D, ASP61C, ASP61D, CYS140C, CYS140D, CYS318C, CYS318D, CYS44C, CYS44D, GLN154C, GLN154D, GLN163C, GLN163D, GLN167C, GLN167D, GLN307C, GLN307D, GLN328C, GLN328D, GLN63C, GLN63D, GLU132C, GLU132D, GLU133C, GLU133D, GLU158C, GLU158D, GLU166C, GLU166D, GLU170C, GLU170D, GLU181C, GLU181D, GLU301C, GLU301D, GLU327C, GLU327D, GLU332C, GLU332D, GLU47C, GLU47D, GLU67C, GLY159C, GLY159D, GLY174C, GLY174D, GLY203C, GLY203D, GLY41C, GLY41D, HIS141C, HIS141D, HIS298C, HIS298D, HIS321C, HIS321D, HIS83C, HIS83D, ILE104C, ILE104D, ILE139C, ILE139D, ILE142C, ILE142D, ILE168C, ILE168D, ILE178C, ILE178D, ILE317C, ILE317D, ILE85C, ILE85D, LEU143C, LEU143D, LEU145C, LEU145D, LEU152C, LEU152D, LEU156C, LEU156D, LEU295C, LEU295D, LEU310C, LEU310D, LEU316C, LEU316D, LEU331C, LEU331D, LEU38C, LEU38D, LYS200C, LYS200D, LYS311C, LYS311D, MET333C, MET333D, MET81C, MET81D, PHE202C, PHE202D, PHE204C, PHE204D, PHE303C, PHE303D, PHE305C, PHE305D, PHE59C, PHE59D, PRO302C, PRO302D, PRO314C, PRO314D, PRO320C, PRO320D, SER128C, SER128D, SER137C, SER137D, SER164C, SER164D, SER173C, SER173D, SER304C, SER304D, SER326C, SER326D, SER330C, SER330D, THR134C, THR134D, THR138C, THR138D, THR150C, THR150D, THR160C, THR160D, THR319C, THR319D, THR322C, THR322D, THR45C, THR45D, THR84C, THR84D, TRP151C, TRP151D, TRP324C, TRP324D, TYR146C, TYR146D, TYR153C, TYR153D, TYR325C, TYR325D, TYR82C, TYR82D, VAL131C, VAL131D, VAL162C, VAL162D, VAL165C, VAL165D, VAL171C, VAL171D, VAL195C, VAL195D, VAL197C, VAL197D, VAL46C, VAL46D
• D-E: ASN254D, ASN254E, ASP255D, ASP255E, GLN230E, GLN260D, GLU247D, GLU247E, HIS248D, HIS248E, LYS114D, LYS114E, LYS259D, LYS259E, PHE256D, PHE256E, PRO211D, THR228D, THR228E, THR257D, THR257E, TYR212D, TYR212E, TYR227D, TYR227E
• D-H: ALA265D, ALA344H, ARG262D, ARG289D, ARG342H, ARG343H, ARG348H, ARG354H, ARG99H, ASP231D, ASP53H, GLN224D, GLN230D, GLN235D, GLN260D, GLN263D, GLU351H, GLY264D, GLY347H, ILE207D, ILE258D, ILE345H, ILE349H, LEU233D, LEU353H, LEU54H, LYS259D, MET261D, PRO350H, SER236D, SER352H, THR182D, THR346H, TYR234D, VAL226D
• E-F: ALA129E, ALA129F, ALA130E, ALA130F, ALA135E, ALA135F, ALA155E, ALA155F, ALA172E, ALA172F, ALA175E, ALA175F, ALA176E, ALA176F, ALA194E, ALA194F, ALA196E, ALA196F, ALA199E, ALA199F, ALA201E, ALA201F, ALA293E, ALA294E, ALA294F, ALA306E, ALA306F, ALA313E, ALA313F, ALA323E, ALA323F, ALA329E, ALA329F, ALA62F, ARG103E, ARG103F, ARG147E, ARG147F, ARG148E, ARG148F, ARG157E, ARG157F, ARG161E, ARG161F, ARG169E, ARG169F, ARG177E, ARG177F, ARG179E, ARG179F, ARG198E, ARG198F, ARG291E, ARG291F, ARG334E, ARG334F, ARG42E, ARG42F, ASN144E, ASN144F, ASN149E, ASN149F, ASN315E, ASN315F, ASP136E, ASP136F, ASP296E, ASP296F, ASP312E, ASP312F, ASP40E, ASP40F, ASP43E, ASP43F, ASP61E, ASP61F, CYS140E, CYS140F, CYS318E, CYS318F, CYS44E, CYS44F, GLN154E, GLN154F, GLN163E, GLN163F, GLN167E, GLN167F, GLN307E, GLN307F, GLN328E, GLN328F, GLN63E, GLN63F, GLU132E, GLU132F, GLU133E, GLU133F, GLU158E, GLU158F, GLU166E, GLU166F, GLU170E, GLU170F, GLU181E, GLU181F, GLU301E, GLU301F, GLU327E, GLU327F, GLU332E, GLU332F, GLU47E, GLU47F, GLU67E, GLY159E, GLY159F, GLY174E, GLY174F, GLY180F, GLY203E, GLY203F, GLY41E, GLY41F, HIS141E, HIS141F, HIS298E, HIS298F, HIS321E, HIS321F, HIS83E, HIS83F, ILE104E, ILE104F, ILE139E, ILE139F, ILE142E, ILE142F, ILE168E, ILE168F, ILE178E, ILE178F, ILE317E, ILE317F, ILE85E, ILE85F, LEU143E, LEU143F, LEU145E, LEU145F, LEU152E, LEU152F, LEU156E, LEU156F, LEU295E, LEU295F, LEU310F, LEU316E, LEU316F, LEU331E, LEU331F, LEU38E, LEU38F, LYS200E, LYS200F, LYS311E, LYS311F, MET333E, MET333F, MET81E, MET81F, PHE202E, PHE202F, PHE204E, PHE204F, PHE303E, PHE303F, PHE305E, PHE305F, PHE59E, PHE59F, PRO302E, PRO302F, PRO314E, PRO314F, PRO320E, PRO320F, SER128E, SER128F, SER137E, SER137F, SER164E, SER164F, SER173E, SER173F, SER300F, SER304E, SER304F, SER326E, SER326F, SER330E, SER330F, SER64E, THR134E, THR134F, THR138E, THR138F, THR150E, THR150F, THR160E, THR160F, THR319E, THR319F, THR322E, THR322F, THR45E, THR45F, THR84E, THR84F, TRP151E, TRP151F, TRP324E, TRP324F, TYR146E, TYR146F, TYR153E, TYR153F, TYR325E, TYR325F, TYR82E, TYR82F, VAL131E, VAL131F, VAL162E, VAL162F, VAL165E, VAL165F, VAL171E, VAL171F, VAL195E, VAL195F, VAL197E, VAL197F, VAL46E, VAL46F
• E-G: ALA201E, ALA201G, ARG177E, ARG177G, ARG179E, ARG179G, ARG219E, ARG219G, GLN224E, GLN224G, GLU218E, GLU218G, GLY203E, GLY203G, GLY222E, GLY222G, LEU221E, LEU221G, LYS200E, LYS200G, PHE202E, PHE202G, SER220E, SER220G, VAL223E, VAL223G
• E-H: ALA129E, ALA129H, ALA130E, ALA130H, ALA135E, ALA135H, ALA194E, ALA194H, ALA196E, ALA196H, ALA329E, ALA329H, ALA336H, ARG190E, ARG190H, ARG198E, ARG198H, ARG219E, ARG219H, ARG225E, ARG225H, ARG343E, ARG343H, ARG354E, ARG354H, ASN125E, ASN125H, ASN355E, ASN355H, ASP215E, ASP215H, GLN193E, GLN193H, GLN214E, GLN214H, GLN328E, GLN328H, GLU132E, GLU132H, GLU133E, GLU133H, GLU218E, GLU218H, GLU332E, GLU332H, GLY189E, GLY189H, GLY192E, GLY192H, GLY216E, GLY216H, GLY222E, GLY222H, ILE126E, ILE126H, ILE217E, ILE217H, LEU213E, LEU213H, LEU221E, LEU221H, LYS200E, LYS200H, PHE188E, PHE188H, PRO127E, PRO127H, PRO211E, PRO211H, SER128E, SER128H, SER220E, SER220H, THR191E, THR191H, TYR227E, TYR227H, VAL131E, VAL131H, VAL195E, VAL195H, VAL197E, VAL197H, VAL223E, VAL223H
• F-G: ALA129F, ALA129G, ALA130F, ALA130G, ALA135F, ALA135G, ALA194F, ALA194G, ALA196F, ALA196G, ALA329F, ALA329G, ARG190F, ARG190G, ARG198F, ARG198G, ARG219F, ARG219G, ARG225F, ARG225G, ARG343F, ARG343G, ARG354F, ARG354G, ASN125F, ASN125G, ASN355F, ASN355G, ASP210F, ASP215F, ASP215G, CYS356F, CYS356G, GLN193F, GLN193G, GLN214F, GLN214G, GLN328F, GLN328G, GLU132F, GLU132G, GLU133F, GLU133G, GLU218F, GLU218G, GLU332F, GLU332G, GLY189F, GLY189G, GLY192F, GLY192G, GLY216F, GLY216G, GLY222F, GLY222G, ILE126F, ILE126G, ILE217F, ILE217G, LEU213F, LEU213G, LEU221F, LEU221G, LYS200G, LYS359F, LYS359G, PHE188F, PHE188G, PRO127F, PRO127G, PRO211F, PRO211G, SER128F, SER128G, SER220F, SER220G, SER326G, THR191F, THR191G, TYR108G, TYR212F, TYR227F, TYR227G, VAL131F, VAL131G, VAL195F, VAL195G, VAL197F, VAL197G, VAL223F, VAL223G, VAL226F, VAL357F, VAL357G
• F-H: ALA201F, ALA201H, ARG177F, ARG177H, ARG179F, ARG179H, ARG219F, ARG219H, GLN224F, GLN224H, GLU218F, GLU218H, GLY203F, GLY203H, GLY222F, GLY222H, LEU221F, LEU221H, LYS200F, LYS200H, PHE202F, PHE202H, SER220F, SER220H, VAL223F, VAL223H
• G-H: ALA129G, ALA129H, ALA130G, ALA130H, ALA135G, ALA135H, ALA155G, ALA155H, ALA172G, ALA172H, ALA175G, ALA175H, ALA176G, ALA176H, ALA194G, ALA194H, ALA196G, ALA196H, ALA199G, ALA199H, ALA201G, ALA201H, ALA293H, ALA294G, ALA294H, ALA306G, ALA306H, ALA313G, ALA313H, ALA323G, ALA323H, ALA329G, ALA329H, ALA62H, ARG103G, ARG103H, ARG147G, ARG147H, ARG148G, ARG148H, ARG157G, ARG157H, ARG161G, ARG161H, ARG169G, ARG169H, ARG177G, ARG177H, ARG179G, ARG179H, ARG198G, ARG198H, ARG291G, ARG291H, ARG334G, ARG334H, ARG42G, ARG42H, ASN144G, ASN144H, ASN149G, ASN149H, ASN315G, ASN315H, ASP136G, ASP136H, ASP296G, ASP296H, ASP312G, ASP312H, ASP40G, ASP40H, ASP43G, ASP43H, ASP61G, ASP61H, CYS140G, CYS140H, CYS318G, CYS318H, CYS44G, CYS44H, GLN154G, GLN154H, GLN163G, GLN163H, GLN167G, GLN167H, GLN307G, GLN307H, GLN328G, GLN328H, GLN63G, GLN63H, GLU132G, GLU132H, GLU133G, GLU133H, GLU158G, GLU158H, GLU166G, GLU166H, GLU170G, GLU170H, GLU181G, GLU181H, GLU301G, GLU301H, GLU327G, GLU327H, GLU332G, GLU332H, GLU47G, GLU47H, GLU67G, GLY159G, GLY159H, GLY174G, GLY174H, GLY180H, GLY203G, GLY203H, GLY41G, GLY41H, HIS141G, HIS141H, HIS298G, HIS298H, HIS321G, HIS321H, HIS83G, HIS83H, ILE104G, ILE104H, ILE139G, ILE139H, ILE142G, ILE142H, ILE168G, ILE168H, ILE178G, ILE178H, ILE317G, ILE317H, ILE85G, ILE85H, LEU143G, LEU143H, LEU145G, LEU145H, LEU152G, LEU152H, LEU156G, LEU156H, LEU295G, LEU295H, LEU310G, LEU310H, LEU316G, LEU316H, LEU331G, LEU331H, LEU38G, LEU38H, LYS200G, LYS200H, LYS311G, LYS311H, MET333G, MET333H, MET81G, MET81H, PHE202G, PHE202H, PHE204G, PHE204H, PHE303G, PHE303H, PHE305G, PHE305H, PHE59G, PHE59H, PRO302G, PRO302H, PRO314G, PRO314H, PRO320G, PRO320H, SER128G, SER128H, SER137G, SER137H, SER164G, SER164H, SER173G, SER173H, SER300H, SER304G, SER304H, SER326G, SER326H, SER330G, SER330H, THR134G, THR134H, THR138G, THR138H, THR150G, THR150H, THR160G, THR160H, THR319G, THR319H, THR322G, THR322H, THR45G, THR45H, THR84G, THR84H, TRP151G, TRP151H, TRP324G, TRP324H, TYR146G, TYR146H, TYR153G, TYR153H, TYR325G, TYR325H, TYR82G, TYR82H, VAL131G, VAL131H, VAL162G, VAL162H, VAL165G, VAL165H, VAL171G, VAL171H, VAL195G, VAL195H, VAL197G, VAL197H, VAL46G, VAL46H