2OM2

crystal structure of human g[alpha]i1 bound to the goloco motif of rgs14

• Total interactions analyzed: 6
• Total true interactions: 2
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 154
  • Norm. En. per Res.: -4.0421
• Hub Node: A(1)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-80.8875	-59.6782	-479.021	-619.5866	154	34	14	20557	3	48	29
C-D	-74.9705	-34.1294	-513.378	-622.4779	154	21	15	20672	2	47	28

Interface residues

• A-B: ALA101A, ALA104A, ALA111A, ALA113A, ALA114A, ALA152A, ALA235A, ALA41A, ALA512B, ALA71A, ALA83A, ALA87A, ARG100A, ARG105A, ARG176A, ARG178A, ARG205A, ARG208A, ARG242A, ARG506B, ARG516B, ARG520B, ARG86A, ARG90A, ASN149A, ASN241A, ASN256A, ASN505B, ASN76A, ASP102A, ASP103A, ASP150A, ASP200A, ASP229A, ASP237A, ASP251A, ASP496B, ASP514B, ASP523B, ASP94A, CYS214A, CYS224A, GLN106A, GLN147A, GLN204A, GLN508B, GLN515B, GLN531B, GLN68A, GLN79A, GLU116A, GLU207A, GLU238A, GLU239A, GLU245A, GLU43A, GLU498B, GLU502B, GLU522B, GLU528B, GLY112A, GLY117A, GLY202A, GLY203A, GLY40A, GLY42A, GLY45A, GLY499B, GLY511B, GLY517B, GLY89A, HIS244A, HIS513B, ILE212A, ILE221A, ILE222A, ILE253A, ILE497B, ILE78A, ILE81A, ILE82A, ILE84A, ILE85A, ILE93A, LEU107A, LEU110A, LEU123A, LEU130A, LEU148A, LEU232A, LEU234A, LEU249A, LEU37A, LEU38A, LEU39A, LEU500B, LEU503B, LEU504B, LEU518B, LEU519B, LEU524B, LEU526B, LEU530B, LYS180A, LYS209A, LYS210A, LYS248A, LYS270A, LYS46A, LYS51A, LYS521B, LYS70A, LYS92A, MET240A, MET247A, MET88A, PHE108A, PHE215A, PHE223A, PHE250A, PHE259A, PHE529B, PHE95A, PRO527B, SER151A, SER206A, SER246A, SER252A, SER44A, SER47A, SER509B, SER510B, SER75A, SER80A, THR177A, THR181A, THR182A, THR48A, THR77A, TRP211A, TRP258A, TYR146A, TYR69A, TYR74A, VAL109A, VAL136A, VAL179A, VAL201A, VAL225A, VAL501B, VAL507B, VAL525B, VAL72A, VAL73A
• C-D: ALA1041C, ALA1071C, ALA1083C, ALA1087C, ALA1101C, ALA1104C, ALA1111C, ALA1113C, ALA1114C, ALA1152C, ALA1235C, ALA1512D, ARG1086C, ARG1090C, ARG1100C, ARG1105C, ARG1176C, ARG1178C, ARG1205C, ARG1208C, ARG1242C, ARG1506D, ARG1516D, ARG1520D, ASN1076C, ASN1149C, ASN1256C, ASN1505D, ASP1094C, ASP1102C, ASP1103C, ASP1150C, ASP1200C, ASP1229C, ASP1237C, ASP1251C, ASP1496D, ASP1514D, ASP1523D, CYS1214C, CYS1224C, CYS1254C, GLN1068C, GLN1079C, GLN1106C, GLN1147C, GLN1204C, GLN1508D, GLN1515D, GLN1531D, GLU1043C, GLU1116C, GLU1207C, GLU1238C, GLU1239C, GLU1245C, GLU1498D, GLU1502D, GLU1522D, GLU1528D, GLY1040C, GLY1042C, GLY1045C, GLY1089C, GLY1112C, GLY1117C, GLY1202C, GLY1203C, GLY1499D, GLY1511D, GLY1517D, HIS1244C, HIS1513D, ILE1078C, ILE1081C, ILE1082C, ILE1084C, ILE1085C, ILE1093C, ILE1184C, ILE1212C, ILE1221C, ILE1253C, ILE1497D, LEU1037C, LEU1038C, LEU1039C, LEU1107C, LEU1110C, LEU1123C, LEU1130C, LEU1148C, LEU1232C, LEU1249C, LEU1500D, LEU1503D, LEU1504D, LEU1518D, LEU1519D, LEU1524D, LEU1526D, LEU1530D, LYS1046C, LYS1051C, LYS1070C, LYS1092C, LYS1180C, LYS1209C, LYS1210C, LYS1248C, LYS1257C, LYS1270C, LYS1521D, MET1088C, MET1119C, MET1240C, MET1247C, PHE1095C, PHE1108C, PHE1215C, PHE1223C, PHE1250C, PHE1259C, PHE1529D, PRO1527D, SER1044C, SER1047C, SER1075C, SER1080C, SER1151C, SER1206C, SER1246C, SER1252C, SER1509D, SER1510D, THR1048C, THR1077C, THR1177C, THR1181C, THR1182C, TRP1211C, TRP1258C, TYR1069C, TYR1074C, TYR1146C, VAL1072C, VAL1073C, VAL1109C, VAL1136C, VAL1179C, VAL1201C, VAL1501D, VAL1507D, VAL1525D