2OF5

oligomeric death domain complex

• Total interactions analyzed: 66
• Total true interactions: 37
• Strongest Interaction:
  • Chains: B-I
  • Int. Res.: 33
  • Norm. En. per Res.: -4.6531
• Hub Node: A(7)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-26.889	2.6389	-65.2558	-89.5059	40	7	1	2992	0	6	15
A-C	0.0	6.5974	-20.857	-14.2596	21	2	0	1009	0	3	11
A-D	0.0	4.7262	-18.2526	-13.5264	19	0	0	858	0	3	10
A-E	0.0	-4.5537	-80.4164	-84.9701	57	5	0	4176	0	15	10
A-F	-21.9865	2.4128	-68.197	-87.7707	40	4	1	2941	0	6	14
A-G	-11.13	-7.2575	-114.586	-132.9735	59	8	0	5088	0	18	12
A-H	-24.8039	-46.6334	-59.8398	-131.2771	34	9	0	2363	2	27	17
B-C	-17.3783	-3.9768	-77.7869	-99.1419	52	4	0	4090	0	15	9
B-D	0.0	2.781	-14.5862	-11.8052	18	1	0	798	0	3	9
B-E	0.0	2.6031	-16.939	-14.3359	16	0	0	775	0	3	7
B-G	0.0	-21.0711	-19.025	-40.0961	18	0	0	810	0	15	10
B-H	-28.8218	22.9923	-133.074	-138.9035	61	12	1	5275	0	18	15
B-I	-25.7745	-46.2504	-81.5267	-153.5517	33	8	0	2613	2	27	17
B-J	-29.0182	-26.8413	-80.4409	-136.3004	40	11	3	3406	3	18	17
C-D	-25.8715	1.9563	-54.3342	-78.2494	38	10	1	2840	0	6	15
C-F	0.0	4.5213	-18.5325	-14.0112	21	0	0	1029	0	3	9
C-G	-43.7	3.159	-62.1403	-102.6813	39	7	1	2787	0	6	14
C-J	-24.7821	-57.1317	-68.8147	-150.7285	36	9	0	2563	4	26	17
D-E	-27.4344	0.485	-66.4632	-93.4126	38	7	1	2898	0	7	14
D-F	-21.1273	-11.1761	-106.075	-138.3784	56	9	0	4986	1	14	9
D-J	-20.7719	17.605	-113.536	-116.7029	56	9	1	4993	0	16	14
D-K	-18.8294	-41.3229	-73.1297	-133.282	35	8	0	2634	2	25	17
E-F	0.0	-26.7219	-41.6482	-68.3701	32	2	0	1614	2	15	13
E-H	-35.7137	-24.3335	-73.8128	-133.8599	40	6	3	3113	2	17	16
E-J	0.0	14.3926	-14.5232	-0.1306	18	0	0	744	0	6	9
E-K	-30.944	20.2185	-114.184	-124.9096	55	5	1	5123	0	14	12
E-L	-12.2732	-49.8172	-78.0347	-140.1251	33	2	0	2561	2	26	18
F-G	0.0	4.9081	-28.9927	-24.0846	23	1	0	1247	0	3	10
H-I	-17.7228	15.1528	-64.7218	-67.2917	33	4	0	2805	3	28	22
H-J	0.0	-29.8058	-21.9441	-51.7499	16	6	0	1056	1	24	14
H-K	0.0	-23.8943	-17.2522	-41.1465	16	0	0	775	0	20	12
H-L	-16.5808	-27.9179	-123.856	-168.3547	54	6	3	5058	3	24	21
I-J	-7.208	-24.8165	-109.817	-141.8415	51	4	2	4842	2	24	20
I-K	0.0	-21.5174	-5.3505	-26.8679	10	0	0	332	0	15	10
I-L	0.0	-14.844	-3.829	-18.673	8	0	0	209	0	14	10
J-K	-15.5267	-6.5315	-72.8105	-94.8687	37	8	0	3437	3	30	26
K-L	-2.7463	1.184	-60.6363	-62.1987	36	2	0	2945	2	30	22

Interface residues

• A-B: ALA124B, ALA150A, ARG126B, ARG147A, ARG166A, ARG170A, ASN121B, ASN151A, ASN155B, ASP144A, CYS148A, GLN122B, GLN125B, GLN142A, GLN157B, GLN159B, GLU130B, GLU132B, GLU162A, GLY128B, HIS152A, HIS152B, HIS154B, ILE145A, LEU123B, LEU127B, LEU193B, LYS149A, LYS149B, PRO129B, PRO153A, PRO153B, SER141A, SER158B, THR143A, TRP131B, TYR146A, VAL156B, VAL160B, VAL161B
• A-C: ALA150A, ALA150C, ASN151A, ASN151C, ASN155A, ASN155C, CYS148A, GLN159A, GLU132A, HIS152A, HIS152C, HIS154A, HIS154C, ILE145A, LYS149A, LYS149C, PRO153A, PRO153C, TRP131A, TYR146A, VAL156A
• A-D: ALA150A, ALA150D, ASN151A, ASN151D, ASN155A, ASN155D, CYS148D, GLN159D, HIS152A, HIS152D, HIS154A, HIS154D, ILE145D, LYS149D, PRO153A, PRO153D, TRP131D, TYR146D, VAL156D
• A-E: ALA124A, ALA163A, ALA186E, ARG118A, ARG126A, ARG166A, ARG168A, ARG170E, ARG185E, ASN121A, ASN151A, ASN155A, ASP117A, ASP144E, CYS148A, GLN119A, GLN122A, GLN125A, GLN142E, GLN157A, GLN159A, GLN169A, GLU130E, GLU132E, GLU162A, GLU188E, GLY128E, GLY139E, HIS152A, HIS154A, ILE120A, ILE145E, ILE165A, LEU136E, LEU138E, LEU140E, LYS149E, MET134E, PHE164A, PHE171E, PRO129E, PRO133E, PRO153A, SER116A, SER137E, SER141E, SER158A, SER179E, THR143E, TRP131E, TRP167E, TYR146E, VAL135E, VAL156A, VAL160A, VAL161A, VAL187E
• A-F: ALA124A, ALA150F, ARG126A, ARG147F, ARG166F, ARG170F, ASN121A, ASN151F, ASN155A, ASP144F, CYS148F, GLN122A, GLN125A, GLN142F, GLN157A, GLN159A, GLU130A, GLU162F, GLY128A, HIS152A, HIS152F, HIS154A, ILE145F, LEU123A, LEU127A, LEU193A, LYS149A, LYS149F, PHE164A, PRO129A, PRO153A, PRO153F, SER141F, SER158A, THR143F, TRP131A, TYR146F, VAL156A, VAL160A, VAL161A
• A-G: ALA124G, ALA163G, ALA186A, ARG118G, ARG126G, ARG166G, ARG168G, ARG185A, ASN121G, ASN151G, ASN155G, ASN182A, ASP117G, ASP144A, CYS148G, GLN119G, GLN122G, GLN125G, GLN142A, GLN157G, GLN159G, GLU130A, GLU132A, GLU162G, GLU188A, GLY128A, GLY139A, GLY183A, HIS152G, HIS154G, ILE120G, ILE145A, ILE165G, LEU136A, LEU138A, LEU140A, LYS149A, MET134A, PHE164G, PHE171A, PRO129A, PRO133A, PRO153G, SER116G, SER137A, SER141A, SER158G, SER179A, THR143A, TRP131A, TRP167A, TYR146A, VAL135A, VAL156A, VAL156G, VAL160G, VAL161G, VAL187A, VAL189A
• A-H: ALA175A, ALA866H, ARG166A, ARG168A, ARG170A, ARG798H, ARG862H, ARG870H, ASN151A, ASP144A, ASP802H, ASP861H, ASP864H, GLN169A, GLN174A, GLN863H, GLU162A, GLU858H, GLU867H, GLU868H, GLY172A, GLY800H, HIS152A, ILE165A, LEU140A, LEU799H, LEU801H, LEU857H, LYS173A, PHE171A, SER114A, SER860H, TRP167A, VAL865H
• B-C: ALA124C, ALA163C, ALA186B, ARG118C, ARG166C, ARG168C, ARG185B, ASN121C, ASN151C, ASN155C, ASP117C, ASP144B, CYS148C, GLN119C, GLN122C, GLN125C, GLN142B, GLN157C, GLN159C, GLN169C, GLU130B, GLU132B, GLU162C, GLU188B, GLY128B, GLY139B, GLY183B, HIS152C, HIS154C, ILE120C, ILE145B, ILE165C, LEU136B, LEU138B, LEU140B, LYS149B, MET134B, PHE171B, PRO129B, PRO133B, SER116C, SER137B, SER141B, SER158C, THR143B, TRP131B, TRP167B, TYR146B, VAL135B, VAL156C, VAL161C, VAL187B
• B-D: ALA150B, ALA150D, ASN151B, ASN151D, ASN155B, ASN155D, CYS148B, GLN159B, HIS152B, HIS152D, HIS154B, HIS154D, LYS149B, PRO153B, PRO153D, TRP131B, TYR146B, VAL156B
• B-E: ALA150B, ALA150E, ASN151E, ASN155B, ASN155E, CYS148E, GLN159E, HIS152E, HIS154B, HIS154E, LYS149E, PRO153B, PRO153E, TRP131E, TYR146E, VAL156E
• B-G: ARG166G, ARG168G, ARG170G, ARG185B, ASN151G, ASP190B, GLN169G, GLU130B, GLU162G, GLU188B, HIS152G, ILE165G, LEU184B, PHE171G, PRO129B, PRO191B, VAL187B, VAL189B
• B-H: ALA124B, ALA163B, ALA805H, ALA807H, ALA856H, ARG118B, ARG126B, ARG166B, ARG168B, ARG815H, ARG821H, ARG862H, ASN121B, ASN151B, ASN155B, ASP117B, ASP802H, ASP861H, CYS148B, GLN119B, GLN122B, GLN125B, GLN157B, GLN159B, GLN169B, GLN818H, GLN855H, GLN859H, GLU162B, GLU199B, GLU816H, GLU858H, GLY800H, GLY811H, HIS152B, HIS154B, HIS809H, ILE120B, ILE165B, LEU123B, LEU801H, LEU808H, LEU810H, LEU828H, LEU852H, MET197B, PHE164B, PRO153B, PRO804H, SER116B, SER158B, SER813H, SER860H, TRP803H, TYR814H, VAL156B, VAL160B, VAL161B, VAL806H, VAL812H, VAL817H
• B-I: ALA175B, ALA866I, ARG166B, ARG168B, ARG170B, ARG798I, ARG862I, ARG870I, ASN151B, ASP144B, ASP802I, ASP861I, ASP864I, GLN169B, GLN174B, GLN863I, GLU162B, GLU858I, GLU867I, GLU868I, GLY172B, GLY800I, ILE165B, LEU140B, LEU799I, LEU801I, LEU857I, LYS173B, PHE171B, SER114B, SER860I, TRP167B, VAL865I
• B-J: ALA150B, ALA796J, ARG147B, ARG166B, ARG170B, ARG798J, ARG821J, ARG825J, ARG833J, ARG862J, ASN151B, ASP144B, ASP802J, ASP826J, ASP827J, ASP829J, CYS148B, GLN142B, GLN831J, GLU162B, GLU830J, GLY797J, GLY800J, HIS152B, ILE145B, ILE832J, LEU793J, LEU799J, LEU801J, LEU828J, LEU836J, LYS149B, PHE824J, PRO153B, SER141B, SER794J, THR143B, TRP803J, TYR146B, VAL795J
• C-D: ALA124D, ALA150C, ARG126D, ARG147C, ARG166C, ARG170C, ASN121D, ASN151C, ASN155D, ASP144C, CYS148C, GLN125D, GLN142C, GLN157D, GLN159D, GLU130D, GLU132D, GLU162C, GLY128D, HIS152C, HIS152D, HIS154D, ILE145C, LEU123D, LEU127D, LYS149C, LYS149D, PRO129D, PRO153C, PRO153D, SER141C, SER158D, THR143C, TRP131D, TYR146C, VAL156D, VAL160D, VAL161D
• C-F: ALA150C, ALA150F, ASN151C, ASN151F, ASN155C, ASN155F, CYS148C, GLN159C, GLU132C, HIS152C, HIS152F, HIS154C, HIS154F, ILE145C, LYS149C, PRO153C, PRO153F, TRP131C, TYR146C, VAL156C, VAL156F
• C-G: ALA124C, ALA150G, ARG126C, ARG147G, ARG166G, ASN121C, ASN151G, ASN155C, ASP144G, CYS148G, GLN122C, GLN125C, GLN142G, GLN157C, GLN159C, GLU130C, GLU162G, GLY128C, HIS152C, HIS152G, HIS154C, HIS154G, ILE145G, LEU123C, LEU127C, LEU193C, LYS149C, LYS149G, PHE164C, PRO129C, PRO153C, PRO153G, SER158C, THR143G, TRP131C, TYR146G, VAL156C, VAL160C, VAL161C
• C-J: ALA175C, ALA866J, ALA871J, ARG166C, ARG168C, ARG170C, ARG798J, ARG862J, ARG870J, ASN151C, ASP144C, ASP802J, ASP861J, ASP864J, GLN169C, GLN174C, GLN859J, GLN863J, GLU162C, GLU858J, GLU867J, GLU868J, GLY172C, GLY800J, HIS152C, ILE165C, LEU140C, LEU799J, LEU801J, LEU857J, LYS173C, PHE171C, SER114C, SER860J, TRP167C, VAL865J
• D-E: ALA124E, ALA150D, ARG126E, ARG147D, ARG166D, ARG170D, ASN121E, ASN151D, ASN155E, ASP144D, CYS148D, GLN122E, GLN125E, GLN142D, GLN157E, GLN159E, GLU130E, GLU162D, GLY128E, HIS152D, HIS152E, HIS154E, ILE145D, LEU123E, LEU127E, LYS149D, LYS149E, PRO129E, PRO153D, PRO153E, SER141D, SER158E, THR143D, TRP131E, TYR146D, VAL156E, VAL160E, VAL161E
• D-F: ALA124F, ALA163F, ALA186D, ARG118F, ARG126F, ARG166F, ARG168F, ARG185D, ASN121F, ASN151F, ASN155F, ASP117F, ASP144D, CYS148F, GLN119F, GLN122F, GLN125F, GLN142D, GLN157F, GLN159F, GLN169F, GLU130D, GLU132D, GLU162F, GLU188D, GLY128D, GLY139D, HIS152F, HIS154F, ILE120F, ILE145D, ILE165F, LEU136D, LEU138D, LEU140D, LYS149D, MET134D, PHE164F, PHE171D, PRO129D, PRO133D, PRO153F, SER116F, SER137D, SER141D, SER158F, THR143D, TRP131D, TRP167D, TYR146D, VAL135D, VAL156F, VAL160F, VAL161F, VAL187D, VAL189D
• D-J: ALA124D, ALA163D, ALA805J, ALA807J, ALA856J, ARG118D, ARG126D, ARG166D, ARG168D, ARG815J, ARG821J, ARG862J, ASN121D, ASN151D, ASN155D, ASP117D, ASP802J, ASP861J, GLN119D, GLN122D, GLN125D, GLN157D, GLN159D, GLN169D, GLN818J, GLN855J, GLN859J, GLU162D, GLU816J, GLU858J, GLY800J, GLY811J, HIS152D, HIS154D, HIS809J, ILE120D, ILE165D, LEU123D, LEU801J, LEU808J, LEU810J, LEU852J, MET197D, PRO153D, PRO804J, SER116D, SER158D, SER813J, SER860J, TRP803J, TYR814J, VAL156D, VAL161D, VAL806J, VAL812J, VAL817J
• D-K: ALA175D, ALA866K, ALA871K, ARG166D, ARG168D, ARG170D, ARG798K, ARG862K, ARG870K, ASN151D, ASP144D, ASP802K, ASP861K, ASP864K, GLN169D, GLN174D, GLN863K, GLU162D, GLU858K, GLU867K, GLU868K, GLY172D, GLY800K, HIS152D, ILE165D, LEU140D, LEU799K, LEU801K, LEU857K, LYS173D, PHE171D, SER114D, SER860K, TRP167D, VAL865K
• E-F: ALA175F, ARG147F, ARG166F, ARG168F, ARG170F, ARG185E, ASN151F, ASP144F, ASP190E, GLN169F, GLN174F, GLU130E, GLU162F, GLU188E, GLY128E, GLY172F, HIS152F, HIS196E, ILE165F, LEU127E, LEU140F, LEU184E, LEU193E, LYS173F, PHE171F, PRO129E, PRO133E, PRO191E, SER192E, TRP167F, VAL187E, VAL189E
• E-H: ALA150E, ALA796H, ARG147E, ARG166E, ARG798H, ARG825H, ARG833H, ARG862H, ASN151E, ASP144E, ASP802H, ASP826H, ASP827H, ASP829H, ASP864H, CYS148E, GLN142E, GLN831H, GLU162E, GLU830H, GLY797H, GLY800H, HIS152E, ILE145E, ILE832H, LEU793H, LEU799H, LEU801H, LEU828H, LEU836H, LYS149E, PHE824H, PRO153E, SER141E, SER794H, THR143E, TRP803H, TYR146E, VAL795H, VAL865H
• E-J: ALA150E, ARG819J, ARG821J, ARG825J, ASN151E, ASN155E, ASP826J, ASP827J, GLN818J, GLN831J, GLU823J, HIS152E, HIS154E, HIS822J, ILE820J, PHE824J, PRO153E, TRP803J
• E-K: ALA124E, ALA163E, ALA805K, ALA807K, ALA856K, ARG118E, ARG126E, ARG166E, ARG168E, ARG815K, ARG821K, ASN121E, ASN151E, ASN155E, ASP117E, ASP802K, ASP861K, GLN119E, GLN122E, GLN125E, GLN157E, GLN159E, GLN169E, GLN818K, GLN855K, GLN859K, GLU162E, GLU816K, GLU858K, GLY811K, HIS152E, HIS154E, HIS809K, ILE120E, ILE165E, LEU123E, LEU801K, LEU808K, LEU810K, LEU852K, MET197E, PRO153E, PRO804K, SER116E, SER158E, SER813K, SER860K, TRP803K, TYR814K, VAL156E, VAL160E, VAL161E, VAL806K, VAL812K, VAL817K
• E-L: ALA175E, ALA866L, ALA871L, ARG166E, ARG168E, ARG170E, ARG798L, ARG862L, ARG870L, ASN151E, ASP144E, ASP802L, ASP861L, ASP864L, GLN169E, GLN174E, GLN863L, GLU162E, GLU858L, GLU867L, GLY172E, HIS152E, ILE165E, LEU140E, LEU799L, LEU801L, LEU857L, LYS173E, PHE171E, SER114E, SER860L, TRP167E, VAL865L
• F-G: ALA150F, ALA150G, ARG147F, ASN151F, ASN151G, ASN155F, ASN155G, CYS148F, GLN157G, GLN159F, HIS152F, HIS152G, HIS154F, HIS154G, ILE145F, LYS149F, LYS149G, PRO153F, PRO153G, TRP131F, TYR146F, VAL156F, VAL156G
• H-I: ALA796I, ARG798I, ARG815H, ARG819H, ARG821H, ARG821I, ARG825H, ARG825I, ARG833I, ARG862I, ASP802I, ASP826I, ASP827I, ASP829I, GLN818H, GLN831I, GLU816H, GLU823H, GLU830I, GLY797I, GLY800I, HIS822H, ILE820H, ILE832I, LEU793I, LEU799I, LEU801I, LEU828I, PHE824I, SER813H, TRP803I, TYR814H, VAL795I
• H-J: ARG821H, ARG825H, ARG825J, ASP826H, ASP826J, ASP827H, ASP827J, GLN818H, GLN831H, GLU823H, GLU823J, GLU830J, HIS822H, HIS822J, PHE824H, PHE824J
• H-K: ARG821K, ARG825H, ARG825K, ASP826H, ASP826K, ASP827H, ASP827K, GLN818K, GLN831K, GLU823H, GLU823K, GLU830H, HIS822H, HIS822K, PHE824H, PHE824K
• H-L: ALA796H, ALA805L, ALA807L, ALA840H, ALA856L, ARG815L, ARG819H, ARG821L, ARG833H, ASN791H, ASP802L, ASP826H, ASP827H, ASP829H, ASP861L, GLN789H, GLN818L, GLN831H, GLN855L, GLN859L, GLU816L, GLU823H, GLU830H, GLU841H, GLY797H, GLY800L, GLY811L, HIS809L, HIS834H, ILE820H, ILE832H, LEU792H, LEU793H, LEU801L, LEU808L, LEU810L, LEU836H, MET777H, MET835H, PHE824H, PHE837H, PRO804L, SER790H, SER794H, SER813L, SER838H, SER860L, THR788H, TRP803L, TRP839H, TYR814L, VAL806L, VAL812L, VAL817L
• I-J: ALA796J, ALA805I, ALA807I, ALA840J, ALA856I, ARG815I, ARG819J, ARG821I, ARG833J, ASN791J, ASP802I, ASP826J, ASP827J, ASP829J, ASP861I, GLN789J, GLN818I, GLN831J, GLN859I, GLU816I, GLU823J, GLU830J, GLU841J, GLY811I, HIS809I, HIS822I, HIS834J, LEU792J, LEU793J, LEU801I, LEU808I, LEU810I, LEU828J, LEU836J, MET777J, MET835J, PHE824J, PHE837J, PRO804I, SER790J, SER794J, SER813I, SER838J, SER860I, THR788J, TRP803I, TRP839J, TYR814I, VAL806I, VAL812I, VAL817I
• I-K: ARG821I, ARG825I, ARG825K, ASP826I, ASP826K, ASP827I, ASP827K, GLU823K, HIS822I, PHE824K
• I-L: ARG821L, ARG825I, ARG825L, ASP826I, ASP826L, ASP827I, HIS822L, PHE824I
• J-K: ALA796K, ARG798K, ARG815J, ARG819J, ARG821J, ARG821K, ARG825J, ARG825K, ARG833K, ARG862K, ASP802K, ASP826K, ASP827K, ASP829K, GLN818J, GLN831K, GLU816J, GLU823J, GLU830K, GLY797K, GLY800K, HIS822J, HIS822K, ILE820J, ILE832K, LEU793K, LEU799K, LEU801K, LEU828K, PHE824J, PHE824K, PRO804K, SER794K, SER813J, TRP803K, TYR814J, VAL795K
• K-L: ALA796L, ARG798L, ARG815K, ARG819K, ARG821K, ARG821L, ARG825K, ARG825L, ARG833L, ARG862L, ASP802L, ASP826L, ASP827L, ASP829L, GLN818K, GLN831L, GLU816K, GLU823K, GLU830L, GLY797L, GLY800L, HIS822K, ILE820K, ILE832L, LEU793L, LEU799L, LEU801L, LEU828L, PHE824K, PHE824L, SER794L, SER813K, TRP803L, TYR814K, VAL795L, VAL817K