2ODE

crystal structure of the heterodimeric complex of human rgs8 and activated gi alpha 3

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 93
  • Norm. En. per Res.: -3.3829
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-71.5815	-12.2315	-228.575	-312.388	105	13	2	8946	5	71	57
A-D	-10.4088	2.1752	-57.9542	-66.1878	47	2	0	2593	3	40	35
B-C	-10.1488	8.4155	-62.4799	-64.2132	52	2	0	2699	3	41	36
B-D	0.0	-8.4717	-21.1321	-29.6038	21	0	0	1028	0	8	9
C-D	-72.0296	-22.8646	-219.716	-314.6102	93	10	2	8470	3	66	53

Interface residues

• A-B: ALA117B, ALA235A, ALA83A, ARG119B, ARG128B, ARG161B, ARG164B, ARG178A, ARG205A, ARG208A, ARG242A, ARG86A, ARG90A, ASN122B, ASN76A, ASN82B, ASP114B, ASP124B, ASP157B, ASP200A, ASP237A, ASP59A, ASP64A, CYS214A, CYS66A, GLN116B, GLN126B, GLN145B, GLN147A, GLN204A, GLN68A, GLN79A, GLU115A, GLU120B, GLU129B, GLU155B, GLU186A, GLU207A, GLU236A, GLU238A, GLU239A, GLU65A, GLU77B, GLU80B, GLU81B, GLY183A, GLY202A, GLY203A, GLY42A, GLY60A, HIS213A, ILE123B, ILE184A, ILE212A, ILE78A, LEU153B, LEU234A, LEU74B, LEU83B, LYS149B, LYS156B, LYS180A, LYS209A, LYS210A, LYS54A, LYS75B, MET154B, PHE112B, PHE125B, PHE199A, PHE70B, PHE73B, PHE78B, PRO118B, PRO160B, SER152B, SER158B, SER206A, SER47A, SER62A, SER75A, SER79B, THR127B, THR181A, THR182A, THR187A, THR76B, TRP211A, TYR146A, TYR159B, TYR61A, TYR69A, TYR74A, VAL113B, VAL115B, VAL121B, VAL150B, VAL179A, VAL185A, VAL201A, VAL233A, VAL50A, VAL71A, VAL72A, VAL73A
• A-D: ALA105D, ALA117D, ALA99D, ARG107D, ARG128D, ARG132D, ARG144A, ARG205A, ARG208A, ARG242A, ARG90A, ASN241A, ASP114D, ASP237A, CYS286A, GLN116D, GLN136D, GLU110D, GLU111D, GLU129D, GLU145A, GLU238A, GLU239A, GLU245A, GLU289A, HIS106D, HIS244A, ILE285A, LEU135D, LEU234A, LYS100D, LYS104D, LYS133D, LYS248A, MET240A, PHE109D, PRO118D, PRO282A, PRO288A, SER103D, THR131D, THR284A, TYR287A, VAL102D, VAL113D, VAL115D, VAL233A
• B-C: ALA105B, ALA117B, ALA99B, ARG107B, ARG119B, ARG128B, ARG132B, ARG142C, ARG144C, ARG205C, ARG208C, ARG242C, ARG90C, ASN241C, ASP114B, ASP237C, CYS286C, GLN116B, GLN136B, GLU110B, GLU111B, GLU129B, GLU137B, GLU145C, GLU236C, GLU238C, GLU239C, GLU245C, HIS106B, HIS244C, ILE285C, LEU135B, LEU232C, LEU234C, LEU91C, LYS100B, LYS104B, LYS133B, LYS248C, LYS92C, MET240C, PHE109B, PRO118B, PRO282C, PRO288C, SER103B, THR131B, THR284C, VAL102B, VAL113B, VAL115B, VAL233C
• B-D: ARG128B, ARG128D, ARG132B, ARG132D, ASP114B, ASP114D, GLN116B, GLN116D, GLN126B, GLN126D, GLN136B, GLN136D, GLU120B, GLU129B, GLU129D, LYS133B, LYS133D, PHE125B, PHE125D, VAL115B, VAL115D
• C-D: ALA117D, ALA235C, ARG119D, ARG128D, ARG161D, ARG164D, ARG178C, ARG205C, ARG208C, ARG242C, ARG86C, ARG90C, ASN122D, ASN76C, ASN82D, ASP114D, ASP124D, ASP157D, ASP200C, ASP237C, CYS214C, GLN116D, GLN126D, GLN145D, GLN147C, GLN204C, GLN68C, GLN79C, GLU115C, GLU120D, GLU129D, GLU155D, GLU186C, GLU207C, GLU236C, GLU238C, GLU239C, GLU65C, GLU77D, GLU80D, GLU81D, GLY183C, GLY202C, GLY203C, GLY42C, HIS213C, ILE123D, ILE184C, LEU153D, LEU234C, LEU74D, LEU83D, LYS149D, LYS156D, LYS180C, LYS209C, LYS210C, LYS54C, LYS75D, MET154D, PHE112D, PHE125D, PHE199C, PHE73D, PHE78D, PRO118D, PRO160D, SER152D, SER158D, SER206C, SER47C, SER75C, SER79D, THR127D, THR181C, THR182C, THR187C, THR76D, TRP211C, TYR146C, TYR159D, TYR69C, VAL113D, VAL115D, VAL121D, VAL150D, VAL179C, VAL185C, VAL201C, VAL233C, VAL50C, VAL71C, VAL72C