2OAR

mechanosensitive channel of large conductance (mscl)

• Total interactions analyzed: 10
• Total true interactions: 10
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 162
  • Norm. En. per Res.: -3.0409
• Hub Node: A(4)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-8.1036	-51.4132	-411.742	-471.2589	162	35	35	19862	2	19	18
A-C	0.0	23.1055	-68.1449	-45.0394	54	15	4	3382	0	6	8
A-D	0.0	4.6128	-56.6313	-52.0185	49	10	3	2921	0	4	6
A-E	-5.5788	-73.3414	-418.927	-497.8472	164	54	36	21167	4	19	19
B-C	0.0	-49.0263	-383.888	-432.9143	163	51	35	19717	2	16	17
B-D	0.0	3.5534	-55.4344	-51.881	51	9	3	3032	1	5	8
B-E	-9.5652	12.4246	-45.9945	-43.1351	50	2	1	2637	1	6	7
C-D	-11.986	-55.2911	-425.352	-492.6292	162	63	37	21142	3	18	19
C-E	0.0	7.123	-31.7152	-24.5922	48	1	2	2159	0	5	6
D-E	-7.1986	-59.5876	-393.556	-460.3422	159	44	32	19463	3	17	19

Interface residues

• A-B: ALA10A, ALA122A, ALA122B, ALA18A, ALA18B, ALA20A, ALA20B, ALA26A, ALA26B, ALA29A, ALA29B, ALA50A, ALA50B, ALA75B, ALA76B, ALA83B, ALA85B, ARG118A, ARG118B, ARG11A, ARG45A, ARG58B, ARG98B, ASN125A, ASN125B, ASN13A, ASN13B, ASN44A, ASN49A, ASN70A, ASN70B, ASN78B, ASP108A, ASP108B, ASP119A, ASP119B, ASP16A, ASP16B, ASP36A, ASP36B, ASP53B, ASP68A, ASP68B, GLN105A, GLN105B, GLN110A, GLN110B, GLN123A, GLN123B, GLN51A, GLN51B, GLN65B, GLU102B, GLU104B, GLU116A, GLU116B, GLU7A, GLY107A, GLY107B, GLY12A, GLY12B, GLY24A, GLY24B, GLY47A, GLY55B, GLY60B, GLY64B, ILE117A, ILE117B, ILE14A, ILE14B, ILE23A, ILE23B, ILE38A, ILE39A, ILE43A, ILE46A, ILE56B, ILE59B, ILE61B, ILE67A, ILE67B, ILE77B, ILE82B, LEU113A, LEU113B, LEU114A, LEU114B, LEU120A, LEU120B, LEU121A, LEU121B, LEU17A, LEU17B, LEU30A, LEU42A, LEU57B, LEU69A, LEU69B, LEU72B, LEU73B, LEU89A, LEU89B, LEU97B, LEU9A, LYS33A, LYS6A, PHE27A, PHE27B, PHE34A, PHE5A, PHE79B, PHE80B, PHE8A, PRO106A, PRO106B, PRO41A, PRO93B, SER37A, SER52A, SER52B, SER74B, THR109A, THR109B, THR115A, THR115B, THR124A, THR124B, THR25A, THR25B, THR28A, THR28B, THR32A, THR32B, THR35A, THR40A, THR40B, THR66A, THR66B, TYR87B, TYR94B, VAL103B, VAL111A, VAL111B, VAL112A, VAL112B, VAL15A, VAL15B, VAL19A, VAL19B, VAL21A, VAL21B, VAL22A, VAL22B, VAL31A, VAL31B, VAL48A, VAL54B, VAL71B, VAL86B, VAL90B, VAL91B
• A-C: ALA10A, ALA20C, ALA83C, ARG11A, ARG98C, ASN13A, ASN95C, ASP108C, GLN105C, GLN110A, GLN110C, GLU104C, GLU7A, GLY107C, GLY24C, GLY4A, ILE117A, ILE117C, ILE14A, ILE82C, LEU114A, LEU114C, LEU120A, LEU121A, LEU121C, LEU17A, LEU17C, LEU2A, LEU92C, LEU9A, LYS3A, LYS6A, LYS99C, MET1A, PHE5A, PHE79C, PHE84C, PHE88C, PHE8A, PRO93C, THR124A, THR124C, THR25A, THR25C, THR28C, THR96C, TYR87C, TYR94C, VAL103C, VAL21A, VAL21C, VAL86C, VAL90C, VAL91C
• A-D: ALA20A, ALA83A, ALA85A, ARG11D, ARG98A, ASN13D, ASN95A, ASP108A, GLN105A, GLN110A, GLN110D, GLU7D, GLY107A, GLY4D, ILE117A, ILE117D, ILE14D, ILE82A, LEU114A, LEU114D, LEU120D, LEU121A, LEU121D, LEU17A, LEU17D, LEU2D, LEU92A, LEU9D, LYS3D, LYS6D, LYS99A, MET1D, PHE5D, PHE79A, PHE84A, PHE88A, PHE8D, THR124D, THR25A, THR25D, THR96A, TYR87A, TYR94A, VAL103A, VAL21A, VAL21D, VAL86A, VAL90A, VAL91A
• A-E: ALA10E, ALA122A, ALA122E, ALA18A, ALA18E, ALA20A, ALA20E, ALA26A, ALA26E, ALA29A, ALA29E, ALA50A, ALA50E, ALA75A, ALA76A, ALA83A, ALA85A, ARG118A, ARG118E, ARG11E, ARG45E, ARG58A, ARG98A, ASN125A, ASN125E, ASN13A, ASN13E, ASN44E, ASN49A, ASN49E, ASN70A, ASN70E, ASN78A, ASN95A, ASP108A, ASP108E, ASP119A, ASP119E, ASP16A, ASP16E, ASP36A, ASP36E, ASP53A, ASP68A, ASP68E, GLN105A, GLN105E, GLN110A, GLN110E, GLN123A, GLN123E, GLN51A, GLN51E, GLN65A, GLU102A, GLU104A, GLU116A, GLU116E, GLU7E, GLY101A, GLY107A, GLY107E, GLY12E, GLY24A, GLY24E, GLY47E, GLY55A, GLY60A, GLY64A, ILE117A, ILE117E, ILE14A, ILE14E, ILE23A, ILE23E, ILE38E, ILE39E, ILE43E, ILE46E, ILE56A, ILE59A, ILE61A, ILE67A, ILE67E, ILE77A, ILE82A, LEU113A, LEU113E, LEU114A, LEU114E, LEU120A, LEU120E, LEU121A, LEU121E, LEU17A, LEU17E, LEU30E, LEU42E, LEU57A, LEU69A, LEU69E, LEU72A, LEU73A, LEU89A, LEU89E, LEU97A, LEU9E, LYS33E, LYS6E, PHE27A, PHE27E, PHE34E, PHE5E, PHE79A, PHE80A, PHE8E, PRO106A, PRO106E, PRO41E, PRO93A, SER37E, SER52A, SER52E, SER74A, THR109A, THR109E, THR115A, THR115E, THR124A, THR124E, THR25A, THR25E, THR28A, THR28E, THR32A, THR32E, THR35E, THR40A, THR40E, THR66A, THR66E, TYR87A, TYR94A, VAL103A, VAL111A, VAL111E, VAL112A, VAL112E, VAL15A, VAL15E, VAL19A, VAL19E, VAL21A, VAL21E, VAL22A, VAL22E, VAL31A, VAL31E, VAL48E, VAL54A, VAL71A, VAL86A, VAL90A, VAL91A
• B-C: ALA10B, ALA122B, ALA122C, ALA18B, ALA18C, ALA20B, ALA20C, ALA26B, ALA26C, ALA29B, ALA29C, ALA50B, ALA50C, ALA75C, ALA76C, ALA83C, ALA85C, ARG118B, ARG118C, ARG11B, ARG45B, ARG58C, ARG98C, ASN125B, ASN125C, ASN13B, ASN13C, ASN44B, ASN49B, ASN70B, ASN70C, ASN78C, ASP108B, ASP108C, ASP119B, ASP119C, ASP16B, ASP16C, ASP36B, ASP36C, ASP53C, ASP68B, ASP68C, GLN105B, GLN105C, GLN110B, GLN110C, GLN123B, GLN123C, GLN51B, GLN51C, GLN65C, GLU102C, GLU104B, GLU104C, GLU116B, GLU116C, GLY107B, GLY107C, GLY12B, GLY12C, GLY24B, GLY24C, GLY47B, GLY55C, GLY60C, GLY64C, ILE117B, ILE117C, ILE14B, ILE14C, ILE23B, ILE23C, ILE38B, ILE39B, ILE43B, ILE46B, ILE56C, ILE59C, ILE61C, ILE67B, ILE67C, ILE77C, ILE82C, LEU113B, LEU113C, LEU114B, LEU114C, LEU120B, LEU120C, LEU121B, LEU121C, LEU17B, LEU17C, LEU30B, LEU42B, LEU57C, LEU69B, LEU69C, LEU72C, LEU73C, LEU89B, LEU89C, LEU97C, LEU9B, LYS33B, LYS6B, PHE27B, PHE27C, PHE34B, PHE5B, PHE79C, PHE80C, PHE8B, PRO106B, PRO106C, PRO41B, PRO93C, SER37B, SER52B, SER52C, SER74C, THR109B, THR109C, THR115B, THR115C, THR124B, THR124C, THR25B, THR25C, THR28B, THR28C, THR32B, THR32C, THR35B, THR35C, THR40B, THR40C, THR66B, THR66C, TYR87C, TYR94C, VAL103C, VAL111B, VAL111C, VAL112B, VAL112C, VAL15B, VAL15C, VAL19B, VAL19C, VAL21B, VAL21C, VAL22B, VAL22C, VAL31B, VAL31C, VAL48B, VAL54C, VAL71C, VAL86C, VAL90C, VAL91C
• B-D: ALA20D, ALA83D, ALA85D, ARG11B, ARG98D, ASN13B, ASN95D, ASP108D, GLN105D, GLN110B, GLN110D, GLU7B, GLY107D, GLY4B, ILE117B, ILE117D, ILE14B, ILE82D, LEU114B, LEU114D, LEU120B, LEU121B, LEU121D, LEU17B, LEU17D, LEU2B, LEU92D, LEU9B, LYS3B, LYS6B, LYS99D, MET1B, PHE5B, PHE79D, PHE84D, PHE88D, PHE8B, PRO93D, THR25B, THR25D, THR28D, THR96D, TYR87D, TYR94D, VAL103D, VAL21B, VAL21D, VAL22B, VAL86D, VAL90D, VAL91D
• B-E: ALA20B, ALA83B, ARG11E, ARG98B, ASN13E, ASN95B, ASP108B, GLN105B, GLN110B, GLN110E, GLU104B, GLU7E, GLY107B, GLY4E, ILE117B, ILE117E, ILE14E, ILE82B, LEU114B, LEU114E, LEU120E, LEU121B, LEU121E, LEU17B, LEU17E, LEU2E, LEU92B, LEU9E, LYS3E, LYS6E, LYS99B, MET1E, PHE5E, PHE79B, PHE84B, PHE88B, PHE8E, THR124E, THR25B, THR25E, THR96B, TYR87B, TYR94B, VAL103B, VAL111B, VAL21B, VAL21E, VAL86B, VAL90B, VAL91B
• C-D: ALA10C, ALA122C, ALA122D, ALA18C, ALA18D, ALA20C, ALA20D, ALA26C, ALA26D, ALA29C, ALA29D, ALA50C, ALA50D, ALA75D, ALA76D, ALA83D, ALA85D, ARG118C, ARG118D, ARG11C, ARG45C, ARG58D, ARG98D, ASN125D, ASN13C, ASN13D, ASN44C, ASN49C, ASN70C, ASN70D, ASN78D, ASN95D, ASP108C, ASP108D, ASP119C, ASP119D, ASP16C, ASP16D, ASP36C, ASP36D, ASP53D, ASP68C, ASP68D, GLN105C, GLN105D, GLN110C, GLN110D, GLN123C, GLN123D, GLN51C, GLN51D, GLN65D, GLU102D, GLU104D, GLU116C, GLU116D, GLU7C, GLY107C, GLY107D, GLY12C, GLY12D, GLY24C, GLY24D, GLY47C, GLY55D, GLY60D, GLY64D, ILE117C, ILE117D, ILE14C, ILE14D, ILE23C, ILE23D, ILE38C, ILE39C, ILE43C, ILE46C, ILE56D, ILE59D, ILE61D, ILE67C, ILE67D, ILE77D, ILE82D, LEU113C, LEU113D, LEU114C, LEU114D, LEU120C, LEU120D, LEU121C, LEU121D, LEU17C, LEU17D, LEU30C, LEU42C, LEU57D, LEU69C, LEU69D, LEU72D, LEU73D, LEU89C, LEU89D, LEU97D, LEU9C, LYS33C, LYS6C, PHE27C, PHE27D, PHE34C, PHE5C, PHE79D, PHE80D, PHE8C, PRO106C, PRO106D, PRO41C, PRO93D, SER37C, SER52C, SER52D, SER74D, THR109C, THR109D, THR115C, THR115D, THR124C, THR124D, THR25C, THR25D, THR28C, THR28D, THR32C, THR32D, THR35C, THR40C, THR40D, THR66C, THR66D, TYR87D, TYR94D, VAL103D, VAL111C, VAL111D, VAL112C, VAL112D, VAL15C, VAL15D, VAL19C, VAL19D, VAL21C, VAL21D, VAL22C, VAL22D, VAL31C, VAL31D, VAL48C, VAL54D, VAL71D, VAL86D, VAL90D, VAL91D
• C-E: ALA20E, ALA83E, ARG11C, ARG98E, ASN13C, ASN95E, ASP108E, GLN105E, GLN110C, GLN110E, GLU104E, GLU7C, GLY107E, GLY4C, ILE117C, ILE117E, ILE14C, ILE82E, LEU114C, LEU114E, LEU120C, LEU121C, LEU121E, LEU17C, LEU17E, LEU92E, LEU9C, LYS3C, LYS99E, MET1C, PHE5C, PHE79E, PHE84E, PHE88E, PHE8C, THR124C, THR124E, THR25C, THR25E, THR28E, TYR87E, TYR94E, VAL103E, VAL21C, VAL21E, VAL86E, VAL90E, VAL91E
• D-E: ALA10D, ALA122D, ALA122E, ALA18D, ALA18E, ALA20D, ALA20E, ALA26D, ALA26E, ALA29D, ALA29E, ALA50D, ALA50E, ALA75E, ALA76E, ALA83E, ALA85E, ARG118D, ARG118E, ARG11D, ARG45D, ARG58E, ARG98E, ASN125D, ASN125E, ASN13D, ASN13E, ASN44D, ASN49D, ASN70D, ASN70E, ASN78E, ASP108D, ASP108E, ASP119D, ASP119E, ASP16D, ASP16E, ASP36D, ASP36E, ASP53E, ASP68D, ASP68E, GLN105D, GLN105E, GLN110D, GLN110E, GLN123D, GLN123E, GLN51D, GLN51E, GLN65E, GLU102E, GLU104E, GLU116D, GLU116E, GLY107D, GLY107E, GLY12D, GLY12E, GLY24D, GLY24E, GLY47D, GLY55E, GLY60E, GLY64E, ILE117D, ILE117E, ILE14D, ILE14E, ILE23D, ILE23E, ILE38D, ILE39D, ILE43D, ILE46D, ILE56E, ILE59E, ILE61E, ILE67D, ILE67E, ILE77E, ILE82E, LEU113D, LEU113E, LEU114D, LEU114E, LEU120D, LEU120E, LEU121D, LEU121E, LEU17D, LEU17E, LEU30D, LEU42D, LEU57E, LEU69D, LEU69E, LEU72E, LEU73E, LEU89D, LEU97E, LEU9D, LYS33D, LYS6D, PHE27D, PHE27E, PHE34D, PHE5D, PHE79E, PHE80E, PHE8D, PRO106D, PRO106E, PRO41D, PRO93E, SER37D, SER52D, SER52E, SER74E, THR109D, THR109E, THR115D, THR115E, THR124D, THR124E, THR25D, THR25E, THR28D, THR28E, THR32D, THR32E, THR35D, THR40D, THR66D, THR66E, TYR87E, TYR94E, VAL103E, VAL111D, VAL111E, VAL112D, VAL112E, VAL15D, VAL15E, VAL19D, VAL19E, VAL21D, VAL21E, VAL22D, VAL22E, VAL31D, VAL31E, VAL48D, VAL54E, VAL71E, VAL86E, VAL90E, VAL91E