2NNT

general structural motifs of amyloid protofilaments

• Total interactions analyzed: 6
• Total true interactions: 5
• Strongest Interaction:
  • Chains: C-D
  • Int. Res.: 62
  • Norm. En. per Res.: -10.1576
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-210.4362	52.4453	-407.085	-565.0759	62	27	10	13747	2	10	11
A-C	0.0	0.0	-2.0388	-2.0388	46	0	0	359	0	6	8
B-C	-184.4875	24.653	-444.151	-603.9855	62	25	12	14448	0	10	10
B-D	0.0	0.0	-0.7754	-0.7754	47	0	0	289	0	8	8
C-D	-221.2243	5.8607	-414.406	-629.7696	62	28	11	13568	4	10	10

Interface residues

• A-B: ALA202A, ALA204A, ALA214A, ALA302B, ALA304B, ALA314B, ARG224A, ARG324B, ASN222A, ASN223A, ASN322B, ASN323B, ASP215A, ASP315B, GLU207A, GLU210A, GLU227A, GLU307B, GLU310B, GLU327B, GLY201A, GLY216A, GLY301B, GLY316B, LEU226A, LEU326B, LYS212A, LYS217A, LYS312B, LYS317B, MET200A, MET300B, PHE219A, PHE319B, SER206A, SER228A, SER306B, SER328B, THR203A, THR209A, THR213A, THR218A, THR225A, THR229A, THR303B, THR309B, THR313B, THR318B, THR325B, THR329B, TRP208A, TRP230A, TRP308B, TRP330B, TYR211A, TYR220A, TYR221A, TYR311B, TYR320B, TYR321B, VAL205A, VAL305B
• A-C: ALA202A, ALA402C, ALA404C, ASN222A, ASN223A, ASN423C, GLU207A, GLU407C, GLU410C, GLU427C, GLY201A, GLY216A, GLY401C, LEU226A, LEU426C, LYS212A, LYS412C, MET200A, MET400C, PHE219A, PHE419C, SER206A, SER228A, SER406C, THR203A, THR209A, THR218A, THR225A, THR229A, THR403C, THR409C, THR418C, THR425C, THR429C, TRP208A, TRP230A, TRP408C, TRP430C, TYR211A, TYR220A, TYR221A, TYR411C, TYR420C, TYR421C, VAL205A, VAL405C
• B-C: ALA302B, ALA304B, ALA314B, ALA402C, ALA404C, ALA414C, ARG324B, ARG424C, ASN322B, ASN323B, ASN422C, ASN423C, ASP315B, ASP415C, GLU307B, GLU310B, GLU327B, GLU407C, GLU410C, GLU427C, GLY301B, GLY316B, GLY401C, GLY416C, LEU326B, LEU426C, LYS312B, LYS317B, LYS412C, LYS417C, MET300B, MET400C, PHE319B, PHE419C, SER306B, SER328B, SER406C, SER428C, THR303B, THR309B, THR313B, THR318B, THR325B, THR329B, THR403C, THR409C, THR413C, THR418C, THR425C, THR429C, TRP308B, TRP330B, TRP408C, TRP430C, TYR311B, TYR320B, TYR321B, TYR411C, TYR420C, TYR421C, VAL305B, VAL405C
• B-D: ALA302B, ALA314B, ALA502D, ALA504D, ALA514D, ARG324B, ARG524D, ASN322B, ASN522D, ASN523D, ASP515D, GLU307B, GLU510D, GLU527D, GLY301B, GLY316B, GLY501D, LEU326B, LYS312B, LYS317B, LYS512D, LYS517D, MET500D, PHE319B, PHE519D, SER328B, SER506D, THR303B, THR309B, THR313B, THR318B, THR325B, THR329B, THR503D, THR509D, THR513D, THR525D, THR529D, TRP330B, TRP508D, TYR311B, TYR320B, TYR321B, TYR511D, TYR520D, TYR521D, VAL305B
• C-D: ALA402C, ALA404C, ALA414C, ALA502D, ALA504D, ALA514D, ARG424C, ARG524D, ASN422C, ASN423C, ASN522D, ASN523D, ASP415C, ASP515D, GLU407C, GLU410C, GLU427C, GLU507D, GLU510D, GLU527D, GLY401C, GLY416C, GLY501D, GLY516D, LEU426C, LEU526D, LYS412C, LYS417C, LYS512D, LYS517D, MET400C, MET500D, PHE419C, PHE519D, SER406C, SER428C, SER506D, SER528D, THR403C, THR409C, THR413C, THR418C, THR425C, THR429C, THR503D, THR509D, THR513D, THR518D, THR525D, THR529D, TRP408C, TRP430C, TRP508D, TRP530D, TYR411C, TYR420C, TYR421C, TYR511D, TYR520D, TYR521D, VAL405C, VAL505D