2JDQ

c-terminal domain of influenza a virus polymerase pb2 subunit in complex with human importin alpha5

• Total interactions analyzed: 6
• Total true interactions: 3
• Strongest Interaction:
  • Chains: B-D
  • Int. Res.: 182
  • Norm. En. per Res.: -3.7928
• Hub Node: A(2)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-11.166	28.7309	-165.498	-147.9331	97	5	3	7421	1	11	20
A-E	-137.4994	-29.2434	-471.954	-638.6969	175	34	0	17375	4	49	40
B-D	-124.1373	-83.1452	-483.0	-690.2825	182	32	0	17455	9	56	45

Interface residues

• A-B: ALA291A, ALA295A, ALA371A, ALA379B, ALA384B, ALA470B, ALA475B, ARG299A, ARG300A, ARG460B, ASN257A, ASN286A, ASN336A, ASN380B, ASN461B, ASN466B, ASP287A, ASP294A, ASP327A, ASP328A, ASP378B, ASP430B, CYS298A, CYS337A, CYS424B, CYS429B, CYS469B, GLN218A, GLN223A, GLN290A, GLN330A, GLN332A, GLN341A, GLN341B, GLN372A, GLN390B, GLU303A, GLU421B, GLU457B, GLU473B, GLU474B, GLU482B, GLY296A, GLY326A, GLY423B, GLY477B, HIS345B, ILE289A, ILE293A, ILE323A, ILE329A, ILE334A, ILE386B, ILE388B, ILE425B, ILE465B, ILE472B, ILE481B, LEU217A, LEU256A, LEU262A, LEU263A, LEU301A, LEU335A, LEU344B, LEU419B, LEU422B, LEU471B, LEU478B, LYS222A, LYS417B, LYS426B, PHE264A, PHE382B, PRO254A, PRO350B, PRO383B, PRO427B, PRO467B, SER221A, SER253A, SER260A, SER338A, SER348B, SER387B, THR331A, THR375A, THR391B, THR463B, TRP261A, TYR418B, TYR468B, TYR476B, VAL258A, VAL297A, VAL333A, VAL420B
• A-E: ALA148A, ALA155A, ALA192A, ALA197A, ALA232A, ALA235A, ALA272A, ALA319A, ALA367A, ALA371A, ALA400A, ALA401A, ALA403A, ALA407A, ALA443A, ALA717E, ALA750E, ALA757E, ARG107A, ARG163A, ARG225A, ARG230A, ARG241A, ARG318A, ARG370A, ARG452A, ARG692E, ARG703E, ARG737E, ARG739E, ARG753E, ARG755E, ASN115A, ASN153A, ASN158A, ASN195A, ASN231A, ASN238A, ASN286A, ASN322A, ASN364A, ASN369A, ASN406A, ASN445A, ASN449A, ASN715E, ASP184A, ASP199A, ASP273A, ASP283A, ASP287A, ASP327A, ASP328A, ASP701E, ASP740E, CYS203A, CYS359A, GLN161A, GLN188A, GLN330A, GLN332A, GLN372A, GLN415A, GLN441A, GLN490A, GLN494A, GLU113A, GLU146A, GLU187A, GLU357A, GLU399A, GLU448A, GLU501A, GLU507A, GLU720E, GLY157A, GLY194A, GLY198A, GLY284A, GLY321A, GLY326A, GLY368A, GLY410A, GLY411A, GLY446A, GLY505A, GLY693E, GLY698E, GLY719E, ILE118A, ILE154A, ILE196A, ILE289A, ILE323A, ILE362A, ILE365A, ILE373A, ILE404A, ILE439A, ILE696E, ILE754E, LEU109A, LEU110A, LEU160A, LEU317A, LEU444A, LEU691E, LEU695E, LEU697E, LEU716E, LEU733E, LYS108A, LYS112A, LYS243A, LYS288A, LYS311A, LYS356A, LYS398A, LYS438A, LYS699E, LYS718E, LYS721E, LYS736E, LYS738E, LYS752E, MET735E, MET756E, PHE145A, PHE694E, PRO114A, PRO116A, PRO117A, PRO285A, PRO315A, SER111A, SER156A, SER159A, SER200A, SER237A, SER244A, SER279A, SER282A, SER314A, SER363A, SER409A, SER412A, SER437A, SER714E, SER741E, THR152A, THR162A, THR227A, THR325A, THR331A, THR361A, THR366A, THR405A, THR408A, THR506A, THR749E, THR751E, TRP149A, TRP191A, TRP234A, TRP276A, TRP360A, TRP402A, TYR280A, TYR704E, VAL150A, VAL185A, VAL190A, VAL324A, VAL440A, VAL442A
• B-D: ALA148B, ALA155B, ALA192B, ALA197B, ALA232B, ALA235B, ALA272B, ALA319B, ALA367B, ALA371B, ALA400B, ALA401B, ALA403B, ALA407B, ALA443B, ALA717D, ALA750D, ARG107B, ARG163B, ARG225B, ARG230B, ARG241B, ARG318B, ARG370B, ARG395B, ARG452B, ARG692D, ARG703D, ARG737D, ARG739D, ARG753D, ARG755D, ASN115B, ASN153B, ASN158B, ASN195B, ASN231B, ASN238B, ASN286B, ASN322B, ASN364B, ASN369B, ASN406B, ASN445B, ASN449B, ASN715D, ASP184B, ASP199B, ASP269B, ASP273B, ASP283B, ASP287B, ASP327B, ASP328B, ASP498B, ASP508B, ASP701D, ASP740D, CYS203B, CYS359B, GLN161B, GLN188B, GLN290B, GLN330B, GLN332B, GLN372B, GLN374B, GLN415B, GLN441B, GLN494B, GLN748D, GLU113B, GLU146B, GLU183B, GLU187B, GLU357B, GLU399B, GLU448B, GLU501B, GLU507B, GLU509B, GLU720D, GLY157B, GLY194B, GLY198B, GLY242B, GLY284B, GLY321B, GLY326B, GLY368B, GLY410B, GLY411B, GLY446B, GLY505B, GLY693D, GLY698D, GLY719D, ILE118B, ILE154B, ILE166B, ILE196B, ILE289B, ILE323B, ILE329B, ILE362B, ILE365B, ILE373B, ILE404B, ILE439B, ILE696D, ILE754D, LEU110B, LEU160B, LEU335B, LEU444B, LEU691D, LEU695D, LEU697D, LEU716D, LEU733D, LYS108B, LYS112B, LYS243B, LYS288B, LYS311B, LYS356B, LYS398B, LYS438B, LYS699D, LYS718D, LYS721D, LYS736D, LYS738D, LYS752D, MET735D, MET756D, PHE145B, PHE694D, PRO114B, PRO116B, PRO285B, PRO315B, SER111B, SER156B, SER159B, SER200B, SER237B, SER279B, SER282B, SER314B, SER363B, SER409B, SER412B, SER437B, SER714D, SER741D, THR152B, THR162B, THR227B, THR325B, THR331B, THR361B, THR366B, THR405B, THR408B, THR506B, THR749D, THR751D, TRP149B, TRP191B, TRP234B, TRP276B, TRP360B, TRP402B, TYR280B, TYR704D, VAL150B, VAL185B, VAL190B, VAL324B, VAL440B, VAL442B