2J9D

structure of glnk1 with bound effectors indicates regulatory mechanism for ammonia uptake

• Total interactions analyzed: 66
• Total true interactions: 36
• Strongest Interaction:
  • Chains: J-L
  • Int. Res.: 115
  • Norm. En. per Res.: -5.6537
• Hub Node: A(5)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-118.4799	-92.2919	-322.517	-533.2889	105	19	15	13998	10	56	60
A-C	-137.7432	-96.3487	-332.41	-566.502	107	24	14	14165	11	55	58
A-D	0.0	0.0	-0.011	-0.011	6	0	0	11	0	0	2
A-E	0.0	0.0	-0.1049	-0.1049	2	0	0	12	0	3	1
A-F	0.0	-2.3712	-51.1107	-53.4819	36	0	2	2344	2	23	15
B-C	-167.7069	-66.6353	-372.334	-606.6761	114	25	16	15527	10	55	57
B-D	0.0	0.0	-0.0081	-0.0081	2	0	0	1	0	1	1
B-E	-7.5585	3.5924	-78.6814	-82.6475	63	6	0	4344	4	38	32
B-F	0.0	0.3788	-5.7597	-5.3809	12	0	0	364	1	4	5
C-D	0.0	-20.0083	-51.2383	-71.2466	33	3	2	2227	0	21	15
C-E	-41.4923	-36.068	-75.1723	-152.7326	36	10	6	3150	2	15	15
D-E	-141.0801	-87.9668	-397.391	-626.4379	119	26	16	16485	13	62	66
D-F	-135.6051	-67.6844	-322.552	-525.8415	105	24	14	13967	9	51	56
D-G	0.0	6.2118	-0.331	5.8808	9	0	0	65	0	5	6
D-H	-12.7843	23.9738	-22.4744	-11.2849	22	2	0	1011	2	19	18
E-F	-167.1745	-86.7165	-349.76	-603.651	113	27	14	14849	11	56	60
E-G	-16.7162	15.3013	-19.3379	-20.7528	18	1	0	627	0	14	12
E-H	0.0	0.0	-0.0314	-0.0314	2	0	0	3	0	0	1
E-I	0.0	6.3252	-0.3185	6.0067	7	0	0	59	0	5	6
F-G	0.0	0.0	-0.0364	-0.0364	2	0	0	3	0	0	1
F-H	0.0	33.7919	-19.8407	13.9512	25	1	0	816	0	17	20
F-I	-11.5982	22.2104	-24.8392	-14.227	25	3	0	976	2	20	17
G-H	-162.1802	-83.4212	-341.641	-587.2424	110	36	15	14964	10	54	59
G-I	-128.995	-101.7908	-325.764	-556.5498	105	26	15	13773	10	55	56
G-J	0.0	2.2429	-75.3501	-73.1072	60	6	3	4384	0	37	34
G-K	0.0	0.0	-0.2573	-0.2573	3	0	0	60	0	4	3
G-L	0.0	12.9896	-0.5283	12.4613	4	0	0	30	0	2	2
H-I	-136.2091	-69.1822	-327.935	-533.3263	111	33	15	14533	10	53	57
H-J	0.0	0.0	-0.0007	-0.0007	2	0	0	2	0	1	2
H-K	0.0	17.5899	-0.8754	16.7145	5	0	0	35	0	4	2
H-L	0.0	8.4088	-58.2677	-49.8589	48	3	2	3010	1	24	22
I-J	0.0	20.9707	-1.534	19.4367	7	0	0	125	0	4	4
I-K	-19.5673	-11.057	-83.7343	-114.3587	60	8	2	4358	2	36	35
J-K	-158.2927	-87.8332	-311.576	-557.7019	103	29	16	13364	11	50	57
J-L	-187.3427	-99.472	-363.362	-650.1768	115	26	15	15088	11	51	55
K-L	-166.1568	-83.2298	-333.447	-582.8335	115	40	15	15320	12	55	58

Interface residues

• A-B: ALA111A, ALA6B, ALA81B, ARG101A, ARG103A, ARG36B, ARG82B, ARG98A, ARG9B, ASN72B, ASN80B, ASN85B, ASP54B, ASP69B, ASP71B, ASP75B, ASP88B, CYS78B, GLN39B, GLU106A, GLU107A, GLU110A, GLU114A, GLU14A, GLU32A, GLU32B, GLU5A, GLU5B, GLU62A, GLU62B, GLU67B, GLU68B, GLU79B, GLU97A, GLU97B, GLY108A, GLY27A, GLY35B, GLY37B, GLY84B, GLY87B, GLY89B, HIS115A, ILE56B, ILE61A, ILE74B, ILE76B, ILE77B, ILE7B, ILE8B, ILE91B, ILE94A, ILE94B, LEU112A, LEU113A, LEU13A, LEU55B, LEU63A, LYS105A, LYS12B, LYS17A, LYS18A, LYS2A, LYS2B, LYS34B, LYS3A, LYS3B, LYS58B, LYS60A, LYS60B, LYS90B, MET1A, MET1B, MET28A, PHE92B, PRO57B, PRO86B, PRO95A, PRO95B, SER0B, SER21A, SER31A, SER31B, THR104A, THR29A, THR83B, VAL100A, VAL102A, VAL16B, VAL26A, VAL30A, VAL33A, VAL33B, VAL38B, VAL4B, VAL53B, VAL59A, VAL59B, VAL64A, VAL65A, VAL70B, VAL93B, VAL96A, VAL96B, VAL99A
• A-C: ALA111C, ALA6A, ALA81A, ARG101C, ARG103C, ARG36A, ARG82A, ARG98C, ARG9A, ASN72A, ASN80A, ASN85A, ASP22C, ASP54A, ASP69A, ASP71A, ASP75A, ASP88A, CYS78A, GLU106C, GLU107C, GLU110C, GLU114C, GLU14C, GLU32A, GLU32C, GLU5A, GLU5C, GLU62A, GLU62C, GLU67A, GLU79A, GLU97A, GLU97C, GLY108C, GLY24C, GLY27C, GLY35A, GLY37A, GLY84A, GLY87A, GLY89A, ILE56A, ILE61C, ILE74A, ILE76A, ILE77A, ILE7A, ILE8A, ILE91A, ILE94A, ILE94C, LEU112C, LEU113C, LEU13C, LEU20C, LEU55A, LEU63C, LYS105C, LYS12A, LYS17C, LYS18C, LYS2A, LYS2C, LYS34A, LYS3A, LYS3C, LYS58A, LYS60A, LYS60C, LYS90A, MET1A, MET1C, MET28C, PHE92A, PRO57A, PRO86A, PRO95A, PRO95C, SER0A, SER21C, SER31A, SER31C, THR104C, THR29C, THR83A, TYR25C, VAL100C, VAL102C, VAL16A, VAL16C, VAL26C, VAL30C, VAL33A, VAL33C, VAL4A, VAL53A, VAL59A, VAL59C, VAL64C, VAL65C, VAL70A, VAL73A, VAL93A, VAL96A, VAL96C, VAL99C
• A-D: ASP54D, LYS34A, LYS34D, PRO57A, PRO57D, VAL53A
• A-E: GLU32A, GLU32E
• A-F: ALA19A, ALA23A, ARG45F, ARG47F, ARG49F, ASN72A, ASN80A, ASP22A, ASP54F, ASP75A, GLU11A, GLU14A, GLU32A, GLU32F, GLU44F, GLU50F, GLU79A, ILE15A, ILE42F, ILE52F, ILE56F, ILE76A, LEU13A, LEU20A, LEU55F, LYS17A, LYS18A, LYS34F, PRO10A, PRO57A, PRO57F, SER21A, TYR46F, TYR51F, VAL16A, VAL53F
• B-C: ALA111B, ALA19B, ALA23B, ALA6C, ALA81C, ARG101B, ARG103B, ARG36C, ARG82C, ARG98B, ARG9C, ASN72C, ASN80C, ASN85C, ASP22B, ASP54C, ASP69C, ASP71C, ASP75C, ASP88C, CYS78C, GLN39C, GLU106B, GLU107B, GLU110B, GLU114B, GLU14B, GLU32B, GLU32C, GLU5B, GLU5C, GLU62B, GLU62C, GLU67C, GLU79C, GLU97B, GLU97C, GLY108B, GLY24B, GLY27B, GLY35C, GLY37C, GLY40C, GLY41C, GLY84C, GLY87C, GLY89C, ILE56C, ILE61B, ILE74C, ILE76C, ILE77C, ILE7C, ILE8C, ILE91C, ILE94B, ILE94C, LEU112B, LEU113B, LEU13B, LEU20B, LEU55C, LEU63B, LYS105B, LYS109B, LYS12C, LYS17B, LYS18B, LYS2B, LYS2C, LYS34C, LYS3B, LYS3C, LYS58C, LYS60B, LYS60C, LYS90C, MET1B, MET1C, MET28B, PHE92C, PRO57C, PRO86C, PRO95B, PRO95C, SER0C, SER21B, SER31B, SER31C, THR104B, THR29B, THR83C, TYR25B, VAL100B, VAL102B, VAL16B, VAL16C, VAL26B, VAL30B, VAL33B, VAL33C, VAL38C, VAL4C, VAL53C, VAL59B, VAL59C, VAL64B, VAL65B, VAL70C, VAL73C, VAL93C, VAL96B, VAL96C, VAL99B
• B-D: GLU32B, GLU32D
• B-E: ALA19B, ARG45E, ARG47E, ARG9B, ARG9E, ASN85B, ASN85E, ASP22B, ASP54B, ASP54E, GLN39B, GLN39E, GLU11B, GLU11E, GLU14B, GLU14E, GLU32B, GLU32E, GLU44E, GLY37B, GLY37E, GLY40E, GLY41E, GLY87B, GLY87E, ILE15B, ILE15E, ILE52E, ILE56B, ILE56E, LEU13B, LEU13E, LEU55B, LEU55E, LYS12B, LYS12E, LYS17B, LYS17E, LYS18B, LYS34B, LYS34E, LYS58B, LYS58E, PRO10B, PRO10E, PRO57B, PRO57E, PRO86E, SER21B, THR83E, TYR46E, TYR51E, VAL26B, VAL30B, VAL30E, VAL33B, VAL33E, VAL38B, VAL38E, VAL53B, VAL53E, VAL59B, VAL59E
• B-F: ASP54B, ASP54F, ILE52F, ILE56B, ILE56F, LEU55B, LEU55F, LYS34B, LYS34F, TYR51F, VAL53B, VAL53F
• C-D: ALA19D, ALA23D, ARG45C, ARG47C, ARG49C, ASN80D, ASP22D, GLU11D, GLU14D, GLU32C, GLU32D, GLU44C, GLU50C, GLU79D, ILE15D, ILE42C, ILE52C, ILE56C, ILE76D, LEU13D, LEU20D, LEU55C, LYS12D, LYS17D, LYS18D, LYS34C, PRO57C, PRO57D, SER21D, TYR46C, TYR51C, VAL16D, VAL53C
• C-E: ARG36C, ARG45C, ARG45E, ARG47C, ARG47E, ARG49C, ARG49E, ASP54C, ASP54E, GLN39C, GLU44C, GLU44E, GLU50C, GLU50E, GLY40C, GLY41C, GLY48E, ILE42C, ILE52C, ILE52E, ILE56C, ILE56E, LEU55C, LEU55E, LYS34C, LYS34E, PRO57C, PRO57E, TYR46C, TYR46E, TYR51C, TYR51E, VAL43C, VAL43E, VAL53C, VAL53E
• D-E: ALA111D, ALA19D, ALA6E, ALA81E, ARG101D, ARG103D, ARG36E, ARG45E, ARG82E, ARG98D, ARG9E, ASN72E, ASN80E, ASN85E, ASP22D, ASP54E, ASP69E, ASP71E, ASP75E, ASP88E, CYS78E, GLU106D, GLU107D, GLU114D, GLU14D, GLU32D, GLU32E, GLU44E, GLU50E, GLU5D, GLU5E, GLU62D, GLU62E, GLU67E, GLU79E, GLU97D, GLU97E, GLY108D, GLY24D, GLY27D, GLY35E, GLY37E, GLY40E, GLY41E, GLY84E, GLY87E, GLY89E, HIS115D, ILE15D, ILE42E, ILE52E, ILE56E, ILE61D, ILE74E, ILE76E, ILE77E, ILE7E, ILE8E, ILE91E, ILE94D, ILE94E, LEU112D, LEU113D, LEU13D, LEU20D, LEU55E, LEU63D, LYS105D, LYS12E, LYS17D, LYS18D, LYS2D, LYS2E, LYS34E, LYS3D, LYS3E, LYS58E, LYS60D, LYS60E, LYS90E, MET1D, MET1E, MET28D, PHE92E, PRO57E, PRO86E, PRO95D, PRO95E, SER0E, SER21D, SER31D, SER31E, THR104D, THR29D, THR83E, TYR25D, TYR51E, VAL100D, VAL102D, VAL16D, VAL16E, VAL26D, VAL30D, VAL33D, VAL33E, VAL38E, VAL43E, VAL4E, VAL53E, VAL59D, VAL59E, VAL64D, VAL65D, VAL70E, VAL73E, VAL93E, VAL96D, VAL96E, VAL99D
• D-F: ALA111F, ALA19F, ALA6D, ALA81D, ARG101F, ARG103F, ARG36D, ARG82D, ARG98F, ARG9D, ASN72D, ASN80D, ASN85D, ASP22F, ASP54D, ASP71D, ASP75D, ASP88D, CYS78D, GLU106F, GLU107F, GLU110F, GLU14F, GLU32D, GLU32F, GLU5D, GLU5F, GLU62D, GLU62F, GLU67D, GLU79D, GLU97D, GLU97F, GLY108F, GLY27F, GLY35D, GLY37D, GLY84D, GLY87D, GLY89D, ILE56D, ILE61F, ILE74D, ILE76D, ILE77D, ILE7D, ILE8D, ILE91D, ILE94D, ILE94F, LEU112F, LEU113F, LEU13F, LEU20F, LEU55D, LEU63F, LYS105F, LYS109F, LYS12D, LYS17F, LYS18F, LYS2D, LYS2F, LYS34D, LYS3D, LYS3F, LYS58D, LYS60D, LYS60F, LYS90D, MET1D, MET1F, MET28F, PHE92D, PRO57D, PRO86D, PRO95D, PRO95F, SER0D, SER21F, SER31D, SER31F, THR104F, THR29F, THR83D, TYR25F, VAL100F, VAL102F, VAL16D, VAL16F, VAL26F, VAL30F, VAL33D, VAL33F, VAL4D, VAL59D, VAL59F, VAL64F, VAL65F, VAL70D, VAL73D, VAL93D, VAL96D, VAL96F, VAL99F
• D-G: ARG98D, ARG98G, GLU97D, GLU97G, GLY-1D, GLY-1G, LYS2D, PRO95D, SER0D
• D-H: ASN72H, ASP69H, ASP71D, ASP71H, GLU67D, GLU67H, GLU68D, GLU68H, GLY-1D, GLY-1H, ILE74D, LYS109H, LYS2D, LYS2H, LYS66H, MET1D, PRO95D, SER0D, SER0H, VAL70D, VAL70H, VAL93D
• E-F: ALA111E, ALA19E, ALA23E, ALA6F, ALA81F, ARG101E, ARG103E, ARG36F, ARG82F, ARG98E, ARG9F, ASN72F, ASN80F, ASN85F, ASP22E, ASP54F, ASP69F, ASP71F, ASP75F, ASP88F, CYS78F, GLU106E, GLU107E, GLU110E, GLU113E, GLU114E, GLU14E, GLU32E, GLU32F, GLU5E, GLU5F, GLU62E, GLU62F, GLU67F, GLU79F, GLU97E, GLU97F, GLY108E, GLY24E, GLY27E, GLY35F, GLY37F, GLY41F, GLY84F, GLY87F, GLY89F, ILE52F, ILE56F, ILE61E, ILE74F, ILE76F, ILE77F, ILE7F, ILE8F, ILE91F, ILE94E, ILE94F, LEU112E, LEU13E, LEU20E, LEU55F, LEU63E, LYS105E, LYS109E, LYS12F, LYS17E, LYS18E, LYS2E, LYS2F, LYS34F, LYS3E, LYS3F, LYS58F, LYS60E, LYS60F, LYS90F, MET1E, MET1F, MET28E, PHE92F, PRO57F, PRO86F, PRO95E, PRO95F, SER0F, SER21E, SER31E, SER31F, THR104E, THR29E, THR83F, TYR25E, VAL100E, VAL102E, VAL16E, VAL16F, VAL26E, VAL30E, VAL33E, VAL33F, VAL38F, VAL4F, VAL53F, VAL59E, VAL59F, VAL64E, VAL65E, VAL70F, VAL73F, VAL93F, VAL96E, VAL96F, VAL99E
• E-G: GLU67E, GLU67G, GLU68E, GLU68G, GLU97E, GLU97G, GLY-1E, GLY-1G, LYS109E, LYS2E, LYS2G, MET1E, MET1G, PRO95E, PRO95G, SER0E, SER0G, VAL70E
• E-H: GLU97E, GLU97H
• E-I: ARG98E, GLU97E, GLU97I, GLY-1I, LYS2I, PRO95I, SER0I
• F-G: GLU97F, GLU97G
• F-H: ARG98F, ARG98H, GLU107F, GLU107H, GLU67F, GLU67H, GLU68F, GLU97F, GLU97H, GLY-1F, GLY-1H, LYS109F, LYS109H, LYS2F, LYS2H, LYS66F, MET1F, MET1H, PRO95F, PRO95H, SER0F, SER0H, VAL96F, VAL96H, VAL99H
• F-I: ASN72F, ASP69F, ASP71F, ASP71I, GLU67F, GLU67I, GLU68F, GLU68I, GLY-1F, GLY-1I, ILE74F, ILE74I, LYS109F, LYS109I, LYS2F, LYS2I, LYS66F, MET1I, PRO95I, SER0F, SER0I, VAL70F, VAL70I, VAL93I, VAL96I
• G-H: ALA111G, ALA19G, ALA23G, ALA6H, ALA81H, ARG101G, ARG103G, ARG36H, ARG82H, ARG98G, ARG9H, ASN72H, ASN80H, ASN85H, ASP22G, ASP54H, ASP69H, ASP71H, ASP75H, ASP88H, CYS78H, GLU106G, GLU107G, GLU110G, GLU114G, GLU14G, GLU32G, GLU32H, GLU5G, GLU5H, GLU62G, GLU62H, GLU67H, GLU79H, GLU97G, GLU97H, GLY108G, GLY24G, GLY27G, GLY35H, GLY37H, GLY84H, GLY87H, GLY89H, ILE15G, ILE56H, ILE61G, ILE74H, ILE76H, ILE77H, ILE7H, ILE8H, ILE91H, ILE94G, ILE94H, LEU112G, LEU113G, LEU13G, LEU20G, LEU55H, LEU63G, LYS105G, LYS12H, LYS17G, LYS18G, LYS2G, LYS2H, LYS34H, LYS3G, LYS3H, LYS58H, LYS60G, LYS60H, LYS90H, MET1G, MET1H, MET28G, PHE92H, PRO57H, PRO86H, PRO95G, PRO95H, SER0H, SER21G, SER31G, SER31H, THR104G, THR29G, THR83H, TYR25G, VAL100G, VAL102G, VAL16G, VAL16H, VAL26G, VAL30G, VAL33G, VAL33H, VAL38H, VAL4H, VAL53H, VAL59G, VAL59H, VAL64G, VAL65G, VAL70H, VAL93H, VAL96G, VAL96H, VAL99G
• G-I: ALA111I, ALA6G, ALA81G, ARG101I, ARG103I, ARG36G, ARG82G, ARG98I, ARG9G, ASN72G, ASN80G, ASN85G, ASP54G, ASP69G, ASP71G, ASP75G, ASP88G, CYS78G, GLU106I, GLU107I, GLU110I, GLU114I, GLU14I, GLU32G, GLU32I, GLU5G, GLU5I, GLU62G, GLU62I, GLU67G, GLU79G, GLU97G, GLU97I, GLY108I, GLY27I, GLY35G, GLY37G, GLY84G, GLY87G, GLY89G, ILE56G, ILE61I, ILE74G, ILE76G, ILE77G, ILE7G, ILE8G, ILE91G, ILE94G, ILE94I, LEU112I, LEU113I, LEU13I, LEU55G, LEU63I, LYS105I, LYS109I, LYS12G, LYS17I, LYS18I, LYS2G, LYS2I, LYS34G, LYS3G, LYS3I, LYS58G, LYS60G, LYS60I, LYS90G, MET1G, MET1I, MET28I, PHE92G, PRO57G, PRO86G, PRO95G, PRO95I, SER0G, SER21I, SER31G, SER31I, THR104I, THR29I, THR83G, TYR25I, VAL100I, VAL102I, VAL16G, VAL26I, VAL30I, VAL33G, VAL33I, VAL38G, VAL4G, VAL53G, VAL59G, VAL59I, VAL64I, VAL65I, VAL70G, VAL73G, VAL93G, VAL96G, VAL96I, VAL99I
• G-J: ALA19G, ALA23G, ARG45J, ARG47J, ARG49J, ARG9G, ARG9J, ASN80G, ASP22G, ASP54G, ASP54J, GLU11G, GLU11J, GLU14G, GLU14J, GLU32G, GLU32J, GLU44J, GLU50J, GLU79G, GLY24G, GLY37G, GLY48J, ILE15G, ILE15J, ILE42J, ILE52J, ILE56G, ILE56J, ILE76G, LEU13G, LEU13J, LEU20G, LEU55G, LEU55J, LYS12G, LYS12J, LYS17G, LYS18G, LYS34G, LYS34J, LYS58G, LYS58J, PRO10G, PRO10J, PRO57G, PRO57J, SER21G, TYR46J, TYR51J, VAL16G, VAL30J, VAL33G, VAL33J, VAL38G, VAL43J, VAL53G, VAL53J, VAL59G, VAL59J
• G-K: LEU55K, LYS34G, LYS34K
• G-L: GLU14G, GLU14L, GLU32G, GLU32L
• H-I: ALA111H, ALA19H, ALA23H, ALA6I, ALA81I, ARG101H, ARG103H, ARG36I, ARG82I, ARG98H, ARG9I, ASN72I, ASN80I, ASN85I, ASP22H, ASP54I, ASP69I, ASP71I, ASP75I, ASP88I, CYS78I, GLN39I, GLU106H, GLU107H, GLU110H, GLU14H, GLU32H, GLU32I, GLU5H, GLU5I, GLU62H, GLU62I, GLU67I, GLU68I, GLU79I, GLU97H, GLU97I, GLY108H, GLY24H, GLY27H, GLY35I, GLY37I, GLY84I, GLY87I, GLY89I, ILE15H, ILE52I, ILE56I, ILE61H, ILE74I, ILE76I, ILE77I, ILE7I, ILE8I, ILE91I, ILE94H, ILE94I, LEU112H, LEU13H, LEU20H, LEU55I, LEU63H, LYS105H, LYS12I, LYS17H, LYS18H, LYS2H, LYS2I, LYS34I, LYS3H, LYS3I, LYS58I, LYS60H, LYS60I, LYS90I, MET1H, MET1I, MET28H, PHE92I, PRO57I, PRO86I, PRO95H, PRO95I, SER0I, SER21H, SER31H, SER31I, THR104H, THR29H, THR83I, TYR25H, VAL100H, VAL102H, VAL16H, VAL16I, VAL26H, VAL30H, VAL33H, VAL33I, VAL38I, VAL4I, VAL53I, VAL59H, VAL59I, VAL64H, VAL65H, VAL70I, VAL93I, VAL96H, VAL96I, VAL99H
• H-J: LYS34H, LYS34J
• H-K: GLU14H, GLU14K, GLU32H, GLU32K, LYS17H
• H-L: ALA19H, ALA81H, ARG45L, ARG47L, ARG49L, ARG82H, ASN80H, ASP22H, CYS78H, GLU11H, GLU11L, GLU14H, GLU14L, GLU32H, GLU32L, GLU44L, GLU50L, GLU79H, ILE15H, ILE15L, ILE42L, ILE52H, ILE52L, ILE56H, ILE56L, ILE76H, LEU13H, LEU13L, LEU55H, LEU55L, LYS12H, LYS12L, LYS17H, LYS18H, LYS34H, LYS34L, PRO10H, PRO10L, PRO57H, PRO57L, THR83H, TYR46L, TYR51L, VAL16H, VAL43L, VAL53H, VAL53L, VAL59H
• I-J: GLU14I, GLU14J, GLU32I, GLU32J, LYS17I, LYS17J, LYS18I
• I-K: ALA19K, ALA23K, ALA81K, ARG36K, ARG45I, ARG47I, ARG82K, ARG9I, ARG9K, ASN80K, ASP22K, ASP54I, ASP54K, GLN39I, GLU11I, GLU11K, GLU14I, GLU14K, GLU32I, GLU32K, GLU44I, GLU50I, ILE15I, ILE15K, ILE42I, ILE52I, ILE56I, ILE56K, LEU13I, LEU13K, LEU20K, LEU55I, LEU55K, LYS12I, LYS12K, LYS17I, LYS17K, LYS18K, LYS34I, LYS34K, LYS58I, LYS58K, PRO10I, PRO10K, PRO57I, PRO57K, SER21K, SER31I, THR83K, TYR46I, TYR51I, VAL16K, VAL30I, VAL33I, VAL33K, VAL43I, VAL53I, VAL53K, VAL59I, VAL59K
• J-K: ALA111J, ALA6K, ALA81K, ARG101J, ARG103J, ARG36K, ARG82K, ARG98J, ARG9K, ASN72K, ASN80K, ASN85K, ASP54K, ASP69K, ASP71K, ASP75K, ASP88K, CYS78K, GLU106J, GLU107J, GLU110J, GLU14J, GLU32J, GLU32K, GLU5J, GLU5K, GLU62J, GLU62K, GLU67K, GLU79K, GLU97J, GLU97K, GLY108J, GLY24J, GLY27J, GLY35K, GLY37K, GLY84K, GLY87K, GLY89K, ILE56K, ILE61J, ILE74K, ILE76K, ILE77K, ILE7K, ILE8K, ILE91K, ILE94J, ILE94K, LEU112J, LEU113J, LEU13J, LEU55K, LEU63J, LYS105J, LYS12K, LYS17J, LYS2J, LYS2K, LYS34K, LYS3J, LYS3K, LYS58K, LYS60J, LYS60K, LYS90K, MET1J, MET1K, MET28J, PHE92K, PRO57K, PRO86K, PRO95J, PRO95K, SER0K, SER21J, SER31J, SER31K, THR104J, THR29J, THR83K, TYR25J, VAL100J, VAL102J, VAL16K, VAL26J, VAL30J, VAL33J, VAL33K, VAL38K, VAL4K, VAL53K, VAL59J, VAL59K, VAL64J, VAL65J, VAL70K, VAL73K, VAL93K, VAL96J, VAL96K, VAL99J
• J-L: ALA111L, ALA19L, ALA23L, ALA6J, ALA81J, ARG101L, ARG103L, ARG36J, ARG82J, ARG98L, ARG9J, ASN72J, ASN80J, ASN85J, ASP22L, ASP54J, ASP69J, ASP71J, ASP75J, ASP88J, CYS78J, GLN39J, GLU106L, GLU107L, GLU110L, GLU14L, GLU32J, GLU32L, GLU5J, GLU5L, GLU62J, GLU62L, GLU67J, GLU68J, GLU79J, GLU97J, GLU97L, GLY108L, GLY24L, GLY27L, GLY35J, GLY37J, GLY40J, GLY41J, GLY84J, GLY87J, GLY89J, ILE52J, ILE56J, ILE61L, ILE74J, ILE76J, ILE77J, ILE7J, ILE8J, ILE91J, ILE94J, ILE94L, LEU112L, LEU113L, LEU13L, LEU20L, LEU55J, LEU63L, LYS105L, LYS109L, LYS12J, LYS17L, LYS18L, LYS2J, LYS2L, LYS34J, LYS3J, LYS3L, LYS58J, LYS60J, LYS60L, LYS90J, MET1J, MET1L, MET28L, PHE92J, PRO57J, PRO86J, PRO95J, PRO95L, SER0J, SER21L, SER31J, SER31L, THR104L, THR29L, THR83J, TYR25L, VAL100L, VAL102L, VAL16J, VAL16L, VAL26L, VAL30L, VAL33J, VAL33L, VAL38J, VAL4J, VAL53J, VAL59J, VAL59L, VAL64L, VAL65L, VAL70J, VAL73J, VAL93J, VAL96J, VAL96L, VAL99L
• K-L: ALA111K, ALA19K, ALA23K, ALA6L, ALA81L, ARG101K, ARG103K, ARG36L, ARG82L, ARG98K, ARG9L, ASN72L, ASN80L, ASN85L, ASP22K, ASP54L, ASP69L, ASP71L, ASP75L, ASP88L, CYS78L, GLN39L, GLU106K, GLU107K, GLU110K, GLU114K, GLU14K, GLU32K, GLU32L, GLU5K, GLU5L, GLU62K, GLU62L, GLU67L, GLU68L, GLU79L, GLU97K, GLU97L, GLY108K, GLY24K, GLY27K, GLY35L, GLY37L, GLY40L, GLY84L, GLY87L, GLY89L, ILE52L, ILE56L, ILE61K, ILE74L, ILE76L, ILE77L, ILE7L, ILE8L, ILE91L, ILE94K, ILE94L, LEU112K, LEU113K, LEU13K, LEU20K, LEU55L, LEU63K, LYS105K, LYS109K, LYS12L, LYS17K, LYS18K, LYS2K, LYS2L, LYS34L, LYS3K, LYS3L, LYS58L, LYS60K, LYS60L, LYS90L, MET1K, MET1L, MET28K, PHE92L, PRO57L, PRO86L, PRO95K, PRO95L, SER0L, SER21K, SER31K, SER31L, THR104K, THR29K, THR83L, TYR25K, VAL100K, VAL102K, VAL16K, VAL16L, VAL26K, VAL30K, VAL33K, VAL33L, VAL38L, VAL4L, VAL53L, VAL59K, VAL59L, VAL64K, VAL65K, VAL70L, VAL73L, VAL93L, VAL96K, VAL96L, VAL99K