2J5T

glutamate 5-kinase from escherichia coli complexed with glutamate

• Total interactions analyzed: 28
• Total true interactions: 16
• Strongest Interaction:
  • Chains: G-H
  • Int. Res.: 220
  • Norm. En. per Res.: -3.0714
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-B	-68.4467	-37.8669	-541.207	-647.5206	218	25	21	23565	5	50	59
A-C	0.0	0.0	-0.0012	-0.0012	6	0	0	3	0	0	0
A-D	-3.166	-13.8268	-77.1041	-94.0969	40	1	7	3777	0	6	8
B-C	-6.5299	-4.3074	-77.0856	-87.9229	44	1	7	3733	0	7	8
B-D	0.0	0.0	-0.0013	-0.0013	7	0	0	4	0	0	0
C-D	-71.9696	-44.6446	-545.401	-662.0151	216	24	21	23396	6	51	59
C-G	0.0	0.0	-1.1521	-1.1521	9	0	0	145	0	0	2
C-H	-8.9623	-32.7879	-52.9079	-94.6581	39	1	3	2326	2	12	16
D-G	0.0	14.7919	-0.1657	14.6261	6	0	0	24	0	6	6
D-H	0.0	45.8654	-28.6059	17.2595	21	0	2	1070	0	7	4
E-F	-67.0451	-40.0204	-551.901	-658.9665	220	21	21	23712	6	51	57
E-G	-12.2381	-16.7607	-110.509	-139.5078	47	7	6	4528	2	5	9
E-H	0.0	0.0	-0.008	-0.008	8	0	0	9	0	0	0
F-G	0.0	0.0	-0.0146	-0.0146	8	0	0	14	0	0	0
F-H	-11.753	-14.3298	-106.466	-132.5488	50	8	6	4423	2	4	9
G-H	-70.2433	-43.9126	-561.554	-675.7099	220	33	21	24051	6	52	59

Interface residues

• A-B: ALA106A, ALA106B, ALA117A, ALA117B, ALA123A, ALA123B, ALA138A, ALA138B, ALA140A, ALA140B, ALA142A, ALA142B, ALA275A, ALA275B, ALA334A, ALA334B, ALA348A, ALA348B, ALA52A, ALA70A, ALA70B, ALA76A, ALA76B, ALA77A, ALA77B, ARG105A, ARG105B, ARG111A, ARG111B, ARG113A, ARG113B, ARG118A, ARG118B, ARG122A, ARG122B, ARG309A, ARG309B, ARG329A, ARG329B, ARG336A, ARG336B, ARG337A, ARG337B, ARG82A, ARG82B, ASN116A, ASN116B, ASN127A, ASN127B, ASN128A, ASN128B, ASN134A, ASN134B, ASN136A, ASN136B, ASN306A, ASN306B, ASN331A, ASN331B, ASP107A, ASP107B, ASP110A, ASP110B, ASP119A, ASP119B, ASP126A, ASP126B, ASP137A, ASP137B, ASP333A, ASP333B, ASP347A, ASP347B, GLN100A, GLN100B, GLN73A, GLN73B, GLN80A, GLN80B, GLN85A, GLN85B, GLN89A, GLN89B, GLU109A, GLU109B, GLU112A, GLU112B, GLU143A, GLU143B, GLU311A, GLU311B, GLU58A, GLU58B, GLU64A, GLU64B, GLU88A, GLU88B, GLY305A, GLY305B, GLY310A, GLY310B, GLY351A, GLY351B, GLY61A, GLY61B, GLY79A, GLY79B, GLY95B, GLY99A, GLY99B, HIS59A, HIS59B, HIS97A, HIS97B, ILE133A, ILE133B, ILE144A, ILE144B, ILE349A, ILE349B, ILE69A, ILE69B, ILE84A, ILE84B, ILE96A, ILE96B, LEU102A, LEU102B, LEU103A, LEU103B, LEU115A, LEU115B, LEU121A, LEU121B, LEU124A, LEU124B, LEU125A, LEU125B, LEU159A, LEU159B, LEU335A, LEU335B, LEU350A, LEU350B, LEU60A, LEU60B, LEU65A, LEU65B, LEU74A, LEU74B, LEU75A, LEU75B, LEU83A, LEU83B, LEU86A, LEU86B, LEU90B, LYS145A, LYS145B, LYS72A, LYS72B, MET101A, MET101B, MET108A, MET108B, PHE114A, PHE114B, PHE307A, PHE307B, PHE91A, PHE91B, PRO131A, PRO131B, PRO273A, PRO273B, PRO63A, PRO63B, PRO66A, PRO66B, SER308A, SER308B, SER328B, SER332A, SER332B, SER71A, SER71B, SER81A, SER81B, SER92A, SER92B, THR104A, THR104B, THR120A, THR120B, THR141A, THR141B, THR68A, THR68B, TRP87A, TRP87B, TYR330A, TYR330B, TYR352A, TYR352B, TYR354A, TYR354B, VAL129A, VAL129B, VAL130A, VAL130B, VAL132A, VAL132B, VAL139A, VAL139B, VAL78A, VAL78B, VAL98A, VAL98B
• A-C: ARG25A, ARG25C, ARG82A, ARG82C, GLN89A, GLN89C
• A-D: ALA26A, ALA26D, ALA36A, ALA36D, ARG25A, ARG25D, ARG33A, ARG33D, ASN24A, ASN24D, GLN89A, GLN89D, GLU30A, GLU30D, GLU88A, GLU88D, GLY95A, GLY95D, HIS27A, HIS27D, ILE28A, ILE28D, ILE93A, ILE93D, ILE96A, ILE96D, LEU86A, LEU86D, LEU90A, LEU90D, PHE91A, PHE91D, PRO239D, SER92A, SER92D, TYR94A, TYR94D, VAL29A, VAL29D, VAL32A
• B-C: ALA26B, ALA26C, ALA36B, ALA36C, ARG25B, ARG25C, ARG33B, ARG33C, ASN24B, ASN24C, GLN37B, GLN89B, GLN89C, GLU30B, GLU30C, GLU88B, GLU88C, GLY95B, GLY95C, HIS27B, HIS27C, ILE28B, ILE28C, ILE93B, ILE93C, ILE96B, ILE96C, LEU23C, LEU86B, LEU86C, LEU90B, LEU90C, PHE91B, PHE91C, PRO239B, PRO239C, SER92B, SER92C, TYR94B, TYR94C, VAL29B, VAL29C, VAL32B, VAL32C
• B-D: ARG25B, ARG25D, ARG82B, ARG82D, GLN89B, GLN89D, HIS59B
• C-D: ALA106C, ALA106D, ALA117C, ALA117D, ALA123C, ALA123D, ALA138C, ALA138D, ALA140C, ALA140D, ALA142C, ALA142D, ALA275C, ALA275D, ALA334C, ALA334D, ALA348C, ALA348D, ALA52C, ALA70C, ALA70D, ALA76C, ALA76D, ALA77C, ALA77D, ARG105C, ARG105D, ARG111C, ARG111D, ARG113C, ARG113D, ARG118C, ARG118D, ARG122C, ARG122D, ARG309C, ARG309D, ARG329C, ARG329D, ARG336C, ARG336D, ARG337C, ARG337D, ARG82C, ARG82D, ASN116C, ASN116D, ASN127C, ASN127D, ASN128C, ASN128D, ASN134C, ASN134D, ASN136C, ASN136D, ASN306C, ASN306D, ASN331C, ASN331D, ASP107C, ASP107D, ASP110C, ASP110D, ASP119C, ASP119D, ASP126C, ASP126D, ASP137C, ASP137D, ASP333C, ASP333D, ASP347C, ASP347D, GLN100C, GLN100D, GLN73C, GLN73D, GLN80C, GLN80D, GLN85C, GLN85D, GLN89C, GLN89D, GLU109C, GLU109D, GLU112C, GLU112D, GLU143C, GLU143D, GLU311C, GLU311D, GLU58C, GLU58D, GLU64C, GLU64D, GLU88C, GLU88D, GLY305C, GLY305D, GLY310C, GLY310D, GLY351C, GLY351D, GLY61C, GLY61D, GLY79C, GLY79D, GLY99C, GLY99D, HIS59C, HIS59D, HIS97C, HIS97D, ILE133C, ILE133D, ILE144C, ILE144D, ILE349C, ILE349D, ILE69C, ILE69D, ILE84C, ILE84D, ILE96C, ILE96D, LEU102C, LEU102D, LEU103C, LEU103D, LEU115C, LEU115D, LEU121C, LEU121D, LEU124C, LEU124D, LEU125C, LEU125D, LEU159C, LEU159D, LEU350C, LEU350D, LEU60C, LEU60D, LEU65C, LEU65D, LEU74C, LEU74D, LEU75C, LEU75D, LEU83C, LEU83D, LEU86C, LEU86D, LEU90C, LEU90D, LYS145C, LYS145D, LYS72C, LYS72D, MET101C, MET101D, MET108C, MET108D, PHE114C, PHE114D, PHE307C, PHE307D, PHE91D, PRO131C, PRO131D, PRO273C, PRO273D, PRO63C, PRO63D, PRO66C, PRO66D, SER308C, SER308D, SER328C, SER328D, SER332C, SER332D, SER71C, SER71D, SER81C, SER81D, SER92C, SER92D, THR104C, THR104D, THR120C, THR120D, THR141C, THR141D, THR68C, THR68D, TRP87C, TRP87D, TYR330C, TYR330D, TYR352C, TYR352D, TYR354C, TYR354D, VAL129C, VAL129D, VAL130C, VAL130D, VAL132C, VAL132D, VAL139C, VAL139D, VAL78C, VAL78D, VAL98C, VAL98D
• C-G: GLU353G, GLU64C, GLY351G, LEU350G, LEU65C, PRO66C, THR68C, TYR352G, TYR354G
• C-H: ALA286H, ALA334H, ALA339H, ALA67C, ARG321H, ARG336H, ARG337H, ARG57C, ASP333H, GLU282H, GLU319C, GLU64C, GLY212C, GLY213C, GLY305H, GLY320C, GLY340H, HIS341H, ILE278H, ILE300H, ILE338H, ILE349H, ILE53C, ILE69C, LEU318H, LEU335H, LEU350H, LEU65C, LYS301H, LYS72C, PRO63C, PRO66C, SER302H, SER332H, SER71C, THR279H, THR304H, THR68C, VAL303H
• D-G: ARG44D, ASN127D, ASP126D, ASP347G, GLU353G, TYR352G
• D-H: ALA348D, ALA67H, ARG309D, ARG329D, ASP347D, GLN344D, GLU345D, GLU353D, GLU64H, GLY351D, GLY355D, ILE346D, LEU65H, PRO356D, PRO63H, PRO66H, SER343D, THR68H, TYR330D, TYR352D, TYR354D
• E-F: ALA106E, ALA106F, ALA117E, ALA117F, ALA123E, ALA123F, ALA138E, ALA138F, ALA140E, ALA140F, ALA142E, ALA142F, ALA275E, ALA275F, ALA334E, ALA334F, ALA348E, ALA348F, ALA70E, ALA70F, ALA76E, ALA76F, ALA77E, ALA77F, ARG105E, ARG105F, ARG111E, ARG111F, ARG113E, ARG113F, ARG118E, ARG118F, ARG122E, ARG122F, ARG309E, ARG309F, ARG329E, ARG329F, ARG336E, ARG336F, ARG337E, ARG337F, ARG82E, ARG82F, ASN116E, ASN116F, ASN127E, ASN127F, ASN128E, ASN128F, ASN134E, ASN134F, ASN136E, ASN136F, ASN306E, ASN306F, ASN331E, ASN331F, ASP107E, ASP107F, ASP110E, ASP110F, ASP119E, ASP119F, ASP126E, ASP126F, ASP137E, ASP137F, ASP333E, ASP333F, ASP347E, ASP347F, GLN100E, GLN100F, GLN73E, GLN73F, GLN80E, GLN80F, GLN85E, GLN85F, GLN89E, GLN89F, GLU109E, GLU109F, GLU112E, GLU112F, GLU143E, GLU143F, GLU311E, GLU311F, GLU58E, GLU58F, GLU64E, GLU64F, GLU88E, GLU88F, GLY305E, GLY305F, GLY310E, GLY310F, GLY351E, GLY351F, GLY56E, GLY56F, GLY61E, GLY61F, GLY79E, GLY79F, GLY95E, GLY99E, GLY99F, HIS59E, HIS59F, HIS97E, HIS97F, ILE133E, ILE133F, ILE144E, ILE144F, ILE349E, ILE349F, ILE69E, ILE69F, ILE84E, ILE84F, ILE96E, ILE96F, LEU102E, LEU102F, LEU103E, LEU103F, LEU115E, LEU115F, LEU121E, LEU121F, LEU124E, LEU124F, LEU125E, LEU125F, LEU159E, LEU159F, LEU335F, LEU350E, LEU350F, LEU60E, LEU60F, LEU65E, LEU65F, LEU74E, LEU74F, LEU75E, LEU75F, LEU83E, LEU83F, LEU86E, LEU86F, LEU90E, LEU90F, LYS145E, LYS145F, LYS72E, LYS72F, MET101E, MET101F, MET108E, MET108F, PHE114E, PHE114F, PHE307E, PHE307F, PHE91E, PHE91F, PRO131E, PRO131F, PRO273E, PRO273F, PRO63E, PRO63F, PRO66E, PRO66F, SER308E, SER308F, SER328E, SER328F, SER332E, SER332F, SER71E, SER71F, SER81E, SER81F, SER92E, SER92F, THR104E, THR104F, THR120E, THR120F, THR141E, THR141F, THR68E, THR68F, TRP87E, TRP87F, TYR330E, TYR330F, TYR352E, TYR352F, TYR354E, TYR354F, VAL129E, VAL129F, VAL130E, VAL130F, VAL132E, VAL132F, VAL139E, VAL139F, VAL78E, VAL78F, VAL98E, VAL98F
• E-G: ALA26E, ALA26G, ALA36E, ALA36G, ARG25E, ARG25G, ARG33E, ARG33G, ASN24E, ASN24G, GLN34E, GLN34G, GLN37E, GLN37G, GLN89E, GLN89G, GLU30E, GLU30G, GLU88E, GLU88G, GLY240E, GLY240G, GLY95E, GLY95G, HIS27E, HIS27G, ILE28E, ILE28G, ILE93E, ILE93G, ILE96E, ILE96G, LEU86E, LEU86G, LEU90E, LEU90G, PHE91E, PHE91G, PRO239E, PRO239G, SER92E, SER92G, TYR94E, TYR94G, VAL29E, VAL29G, VAL32G
• E-H: ARG25E, ARG25H, ARG82E, ARG82H, GLN89E, GLN89H, HIS59E, HIS59H
• F-G: ARG25F, ARG25G, ARG82F, ARG82G, GLN89F, GLN89G, HIS59F, HIS59G
• F-H: ALA26F, ALA26H, ALA36F, ALA36H, ARG25F, ARG25H, ARG33F, ARG33H, ASN24F, ASN24H, GLN34F, GLN34H, GLN37F, GLN37H, GLN89F, GLN89H, GLU30F, GLU30H, GLU88F, GLU88H, GLY240F, GLY240H, GLY95F, GLY95H, HIS27F, HIS27H, ILE28F, ILE28H, ILE93F, ILE93H, ILE96F, ILE96H, LEU31F, LEU31H, LEU86F, LEU86H, LEU90F, LEU90H, PHE91F, PHE91H, PRO239F, PRO239H, SER92F, SER92H, TYR94F, TYR94H, VAL29F, VAL29H, VAL32F, VAL32H
• G-H: ALA106G, ALA106H, ALA117G, ALA117H, ALA123G, ALA123H, ALA138G, ALA138H, ALA140G, ALA140H, ALA142G, ALA142H, ALA275G, ALA275H, ALA334G, ALA334H, ALA348G, ALA348H, ALA52G, ALA52H, ALA70G, ALA70H, ALA76G, ALA76H, ALA77G, ALA77H, ARG105G, ARG105H, ARG111G, ARG111H, ARG113G, ARG113H, ARG118G, ARG118H, ARG122G, ARG122H, ARG309G, ARG309H, ARG329G, ARG329H, ARG336G, ARG336H, ARG337G, ARG337H, ARG82G, ARG82H, ASN116G, ASN116H, ASN127G, ASN127H, ASN128G, ASN128H, ASN134G, ASN134H, ASN136G, ASN136H, ASN306G, ASN306H, ASN331G, ASN331H, ASP107G, ASP107H, ASP110G, ASP110H, ASP119G, ASP119H, ASP126G, ASP126H, ASP137G, ASP137H, ASP333G, ASP333H, ASP347G, ASP347H, GLN100G, GLN100H, GLN73G, GLN73H, GLN80G, GLN80H, GLN85G, GLN85H, GLN89G, GLN89H, GLU109G, GLU109H, GLU112G, GLU112H, GLU143G, GLU143H, GLU311G, GLU311H, GLU58G, GLU58H, GLU64G, GLU64H, GLU88G, GLU88H, GLY305G, GLY305H, GLY310G, GLY310H, GLY351G, GLY351H, GLY56H, GLY61G, GLY61H, GLY79G, GLY79H, GLY95G, GLY99G, GLY99H, HIS59G, HIS59H, HIS97G, HIS97H, ILE133G, ILE133H, ILE144G, ILE144H, ILE349G, ILE349H, ILE69G, ILE69H, ILE84G, ILE84H, ILE96G, ILE96H, LEU102G, LEU102H, LEU103G, LEU103H, LEU115G, LEU115H, LEU121G, LEU121H, LEU124G, LEU124H, LEU125G, LEU125H, LEU159G, LEU159H, LEU335G, LEU335H, LEU350G, LEU350H, LEU60G, LEU60H, LEU65G, LEU65H, LEU74G, LEU74H, LEU75G, LEU75H, LEU83G, LEU83H, LEU86G, LEU86H, LEU90H, LYS145G, LYS145H, LYS72G, LYS72H, MET101G, MET101H, MET108G, MET108H, PHE114G, PHE114H, PHE307G, PHE307H, PHE91G, PHE91H, PRO131G, PRO131H, PRO273G, PRO273H, PRO63G, PRO63H, PRO66G, PRO66H, SER308G, SER308H, SER328H, SER332G, SER332H, SER71G, SER71H, SER81G, SER81H, SER92G, SER92H, THR104G, THR104H, THR120G, THR120H, THR141G, THR141H, THR68G, THR68H, TRP87G, TRP87H, TYR330G, TYR330H, TYR352G, TYR352H, TYR354G, TYR354H, VAL129G, VAL129H, VAL130G, VAL130H, VAL132G, VAL132H, VAL139G, VAL139H, VAL78G, VAL78H, VAL98G, VAL98H