2J0S

the crystal structure of the exon junction complex at 2.2 a resolution

• Total interactions analyzed: 10
• Total true interactions: 5
• Strongest Interaction:
  • Chains: A-T
  • Int. Res.: 145
  • Norm. En. per Res.: -5.2841
• Hub Node: A(3)

All Interactions

Chains	Hydro. Bond Ener. (kJ/mol)	Elec. Ener. (kJ/mol)	VDW. Ener. (kJ/mol)	Tot. Stab. Ener. (kJ/mol)	#int. res.	# Short cont.	#Hydr. int.	#VDW pairs	#salt bridges	#Pot. fav. elec. int	#Pot. unfav. elec. int
A-C	-113.9336	-115.8225	-447.526	-677.2821	154	23	5	16130	12	63	61
A-D	-8.0811	-42.862	-22.1024	-73.0455	39	2	0	941	2	18	13
A-T	-128.0486	-60.6771	-577.466	-766.1917	145	19	2	18285	15	86	87
C-D	-73.3319	-8.6202	-358.648	-440.6001	103	14	9	12803	1	34	33
C-T	-9.1226	12.2784	-89.6745	-86.5187	29	2	0	3110	3	14	18

Interface residues

• A-C: ALA257A, ALA35C, ALA63A, ARG243A, ARG339A, ARG358A, ARG370A, ARG373A, ARG387A, ARG390A, ARG47C, ARG67A, ARG82C, ARG85C, ASN111C, ASN194A, ASN356A, ASN357A, ASN36C, ASN37C, ASN383A, ASN39C, ASN42C, ASP109C, ASP128C, ASP190A, ASP244A, ASP384A, ASP391A, ASP401A, ASP43C, ASP81C, CYS131C, GLN127C, GLN394A, GLN399A, GLN65A, GLN66A, GLN83A, GLU191A, GLU20C, GLU21A, GLU224A, GLU227A, GLU23C, GLU245A, GLU249A, GLU259A, GLU27A, GLU29A, GLU359A, GLU393A, GLU402A, GLY105C, GLY12C, GLY138C, GLY15C, GLY250A, GLY369A, GLY372A, GLY84C, GLY85A, GLY87A, HIS13C, HIS19C, HIS223A, ILE104C, ILE108C, ILE137C, ILE143C, ILE146C, ILE225A, ILE239A, ILE386A, ILE388A, ILE392A, ILE400A, ILE46C, ILE64A, LEU107C, LEU125C, LEU129C, LEU132C, LEU139C, LEU221A, LEU226A, LEU22C, LEU240A, LEU246A, LEU248A, LEU360A, LEU389A, LYS103C, LYS130C, LYS142C, LYS144C, LYS16C, LYS242A, LYS252A, LYS25A, LYS382A, LYS41C, LYS48C, LYS60A, MET23A, MET403A, MET45C, PHE134C, PHE141C, PHE17C, PHE21C, PHE24C, PHE255A, PHE28A, PRO145C, PRO222A, PRO61A, SER102C, SER106C, SER135C, SER38C, SER397A, SER62A, SER82A, SER84A, THR220A, THR247A, THR24A, THR30A, THR398A, THR86A, TRP263A, TYR10C, TYR123C, TYR124C, TYR34C, TYR371A, TYR395A, TYR396A, TYR40C, TYR9C, VAL110C, VAL11C, VAL126C, VAL133C, VAL241A, VAL256A, VAL258A, VAL26A, VAL34A, VAL36A, VAL381A, VAL44C, VAL83C
• A-D: ALA63A, ARG108D, ARG109D, ARG390A, ARG67A, ASN101D, ASN105D, ASN406A, ASP401A, GLN253A, GLN399A, GLN66A, GLU245A, GLU249A, GLU393A, GLU402A, GLU71D, GLU86D, GLU87D, GLY111D, HIS103D, ILE102D, ILE400A, LEU104D, LEU106D, LEU410A, LYS100D, LYS252A, LYS374A, LYS60A, MET405A, PHE254A, PHE255A, PRO404A, THR110D, THR398A, THR85D, VAL36A, VAL70D
• A-T: ALA180A, ALA180T, ALA211A, ALA229T, ARG105A, ARG172A, ARG174A, ARG176T, ARG177A, ARG179A, ARG184T, ARG194T, ARG206A, ARG217T, ARG224T, ARG260A, ARG288A, ARG358A, ARG364A, ARG387A, ARG390A, ASN178T, ASN194A, ASN230A, ASN285A, ASN356A, ASN357A, ASN383A, ASP154A, ASP171T, ASP172T, ASP173T, ASP175T, ASP192T, ASP203A, ASP221T, ASP226T, ASP235A, ASP291A, ASP353A, ASP384A, ASP385A, ASP391A, ASP77A, CYS284A, GLN157A, GLN196T, GLN200A, GLN213A, GLN228T, GLN394A, GLU106A, GLU174T, GLU190T, GLU199A, GLU215T, GLU219T, GLU224A, GLU225T, GLU227T, GLU259A, GLU261A, GLU262A, GLU359A, GLY156A, GLY186T, GLY195T, GLY216T, HIS169T, HIS191T, HIS220T, ILE171A, ILE181A, ILE182T, ILE201A, ILE386A, ILE388A, ILE392A, LEU112A, LEU153A, LEU170T, LEU176A, LEU184A, LEU186A, LEU187T, LEU193A, LEU193T, LEU208A, LEU216A, LEU293A, LEU354A, LEU360A, LEU389A, LYS177T, LYS185T, LYS195A, LYS198A, LYS222T, LYS231A, LYS264A, LYS287A, LYS289A, LYS296A, LYS382A, MET192A, MET228A, MET233A, PHE168A, PHE188T, PHE189T, PHE197A, PHE223T, PHE232A, PHE380A, PRO179T, PRO183T, PRO209A, PRO210A, PRO222A, PRO230T, PRO236A, PRO355A, SER175A, THR107A, THR178A, THR212A, THR229A, THR234A, THR286A, TRP218T, TRP263A, TRP292A, TYR181T, TYR202A, TYR205A, TYR207A, TYR352A, TYR361A, TYR396A, VAL104A, VAL204A, VAL214A, VAL258A, VAL290A, VAL381A
• C-D: ALA50C, ARG108D, ARG109D, ARG120C, ARG152D, ARG27C, ARG62C, ARG68D, ASN101D, ASN105D, ASP107D, ASP128C, ASP147D, ASP29C, ASP66C, CYS131C, CYS149D, GLN127C, GLN67D, GLU117C, GLU120D, GLU49C, GLU58C, GLU59C, GLU68C, GLU71D, GLY111D, GLY115D, GLY118C, GLY138C, GLY153D, GLY30C, GLY72D, GLY79D, HIS103D, HIS140C, HIS53C, ILE102D, ILE137C, ILE143C, ILE146C, ILE63C, ILE64C, ILE74D, ILE99D, LEU104D, LEU106D, LEU107C, LEU113D, LEU118D, LEU119C, LEU125C, LEU129C, LEU132C, LEU136C, LEU139C, LEU32C, LEU60C, LEU75D, LYS100D, LYS114D, LYS130C, LYS142C, LYS144C, LYS31C, LYS54C, MET131D, MET57C, PHE122C, PHE134C, PHE141C, PHE150D, PHE26C, PHE76D, PRO145C, PRO154D, PRO66D, SER135C, SER145D, SER55C, SER67C, SER69D, THR110D, THR117D, THR78D, TRP148D, TRP73D, TYR116D, TYR123C, TYR124C, TYR51C, VAL110C, VAL119D, VAL121C, VAL126C, VAL133C, VAL146D, VAL151D, VAL52C, VAL56C, VAL70D, VAL77D, VAL80D
• C-T: ARG194T, ARG82C, ARG85C, ASP192T, ASP81C, GLN196T, GLU190T, GLU20C, GLY12C, GLY15C, GLY186T, GLY18C, GLY195T, GLY84C, HIS13C, HIS191T, HIS19C, LEU187T, LEU193T, LYS103C, LYS14C, LYS16C, LYS41C, PHE17C, PHE188T, PHE189T, TYR40C, VAL11C, VAL83C